GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | CCL2 | decreases expression | EXP | | 6480464 | CTD | Atorvastatin results in decreased expression of CCL2 mRNA | PMID:12117737 | CCL2 | multiple interactions | EXP | | 6480464 | CTD | Atorvastatin inhibits the reaction [TNF results in increased expression of CCL2 mRNA]; Atorvastatin results in decreased expression of and results in decreased secretion of CCL2 protein; Mevalonic Acid inhibits the reaction [Atorvastatin inhibits the reaction [TNF results in increased expression of CCL2 mRNA]]; Mevalonic Acid inhibits the reaction [Atorvastatin results in decreased expression of CCL2 mRNA] | PMID:12117737 | CCL2 | multiple interactions | ISO | Ccl2 (Rattus norvegicus) | 6480464 | CTD | [dapagliflozin co-treated with Atorvastatin] inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of CCL2 protein]; Atorvastatin inhibits the reaction [sodium arsenite results in increased expression of CCL2 protein] | PMID:25058445 PMID:34939712 | | ||||||||||||||||||||||
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