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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731046
Species: Homo sapiens
RGD Object: Gene
Symbol: CCL2
Name: C-C motif chemokine ligand 2
Acc ID: CHEBI:91222
Term: neocuproine
Definition: A member of the class of phenanthrolines that is 1,10-phenanthroline bearing two methyl substituents at positions 2 and 9.
Chemical ID: MESH:C002701
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CCL2multiple interactionsISOCcl2 (Mus musculus)6480464CTDneocuproine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of CCL2 protein]; neocuproine promotes the reaction [ATP7A protein mutant form inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of CCL2 protein]]PMID:23604539
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