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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731046
Species: Homo sapiens
RGD Object: Gene
Symbol: CCL2
Name: C-C motif chemokine ligand 2
Acc ID: CHEBI:7931
Term: paricalcitol
Definition: A seco-cholestane that has formula C27H44O3.
Chemical ID: MESH:C084656
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CCL2decreases expressionISOCcl2 (Mus musculus)6480464CTDparicalcitol results in decreased expression of CCL2 proteinPMID:20720404
CCL2increases expressionISOCcl2 (Mus musculus)6480464CTDparicalcitol results in increased expression of CCL2 mRNAPMID:25037058
CCL2multiple interactionsISOCcl2 (Mus musculus)6480464CTD[paricalcitol co-treated with Enalapril] results in decreased expression of CCL2 proteinPMID:20720404
CCL2multiple interactionsISOCcl2 (Rattus norvegicus)6480464CTD[paricalcitol co-treated with Enalapril] results in decreased expression of CCL2 proteinPMID:17513326
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