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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3645
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ccl2
Name: C-C motif chemokine ligand 2
Acc ID: CHEBI:177406
Term: Bardoxolone methyl
Definition: null
Chemical ID: MESH:C445068
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ccl2increases expressionISOCCL2 (Homo sapiens)6480464CTDbardoxolone methyl results in increased expression of CCL2 mRNAPMID:35724838
Ccl2multiple interactionsISOCcl2 (Mus musculus)6480464CTDbardoxolone methyl inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased secretion of CCL2 protein]PMID:26918785
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