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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3645
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ccl2
Name: C-C motif chemokine ligand 2
Acc ID: CHEBI:16995
Term: oxalic acid
Definition: An alpha,omega-dicarboxylic acid that is ethane substituted by carboxyl groups at positions 1 and 2.
Chemical ID: MESH:D019815
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ccl2increases expressionISOCCL2 (Homo sapiens)6480464CTDOxalic Acid results in increased expression of CCL2 mRNAPMID:24145091 PMID:37414240
Ccl2multiple interactionsISOCCL2 (Homo sapiens)6480464CTD[Butyric Acid co-treated with Sulfaphenazole] inhibits the reaction [Oxalic Acid results in increased expression of CCL2 mRNA]; Resveratrol inhibits the reaction [Oxalic Acid results in increased expression of CCL2 mRNA]; Sulfaphenazole inhibits the reaction [Oxalic Acid results in increased expression of CCL2 mRNA]PMID:24145091 PMID:37414240
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