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Gene: Nog (noggin) Rattus norvegicus
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Symbol: Nog
Name: noggin
Description: Predicted to have cytokine binding activity and protein homodimerization activity. Involved in several processes, including hippocampus development; learning or memory; and regulation of gliogenesis. Localizes to the axon; extracellular space; and protein-containing complex. Biomarker of acute kidney tubular necrosis and type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in several diseases, including Huntington's disease; cleft lip; dysostosis (multiple); proximal symphalangism; and tarsal-carpal coalition syndrome. Orthologous to human NOG (noggin); PARTICIPATES IN Bone morphogenetic proteins signaling pathway; transforming growth factor-beta superfamily mediated signaling pathway; INTERACTS WITH (20S)-ginsenoside Rg3; 17beta-estradiol; amitriptyline.
Type: protein-coding
RefSeq Status: VALIDATED
Orthologs:
Homo sapiens (human) : NOG (noggin)  HGNC  Alliance
Mus musculus (house mouse) : Nog (noggin)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nog (noggin)
Pan paniscus (bonobo/pygmy chimpanzee) : NOG (noggin)
Canis lupus familiaris (dog) : NOG (noggin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nog (noggin)
Sus scrofa (pig) : NOG (noggin)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01076,811,759 - 76,813,386 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01076,677,612 - 76,679,239 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41077,689,244 - 77,690,871 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11077,703,801 - 77,704,728 (-)NCBI
Celera1073,029,127 - 73,030,754 (-)NCBICelera
Cytogenetic Map10q26NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Nog
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3183
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.