Cdc6 (cell division cycle 6) - Rat Genome Database

Name: Cdc6
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: Cdc6 (cell division cycle 6) Rattus norvegicus

Analyze

Symbol:

Cdc6

Name:

cell division cycle 6

RGD ID:

1309157

Description:

Predicted to enable DNA replication origin binding activity; chromatin binding activity; and kinase binding activity. Involved in cellular response to angiotensin; cellular response to vasopressin; and positive regulation of fibroblast proliferation. Predicted to be located in several cellular components, including intercellular bridge; nucleoplasm; and spindle. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in Meier-Gorlin syndrome 5. Orthologous to human CDC6 (cell division cycle 6); PARTICIPATES IN cell cycle pathway, mitotic; INTERACTS WITH 17beta-estradiol; 2,2',5,5'-tetrachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

cell division control protein 6 homolog; cell division cycle 6 homolog; cell division cycle 6 homolog (S. cerevisiae); LOC360621

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	CDC6 (cell division cycle 6)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Cdc6 (cell division cycle 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Cdc6 (cell division cycle 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	CDC6 (cell division cycle 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	CDC6 (cell division cycle 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Cdc6 (cell division cycle 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	CDC6 (cell division cycle 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	CDC6 (cell division cycle 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Cdc6 (cell division cycle 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	CDC6 (cell division cycle 6)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Cdc6 (cell division cycle 6)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	cdc6 (cell division cycle 6 homolog (S. cerevisiae))	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	CDC6	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Cdc6	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	cdc-6	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	cdc6	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	10	83,864,189 - 83,878,011 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	83,864,638 - 83,878,011 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	10	88,808,558 - 88,821,905 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	88,306,636 - 88,320,009 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	83,699,232 - 83,712,599 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	86,819,477 - 86,833,301 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	86,819,472 - 86,833,402 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	10	86,614,443 - 86,628,265 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	10	87,684,493 - 87,697,865 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	10	87,699,352 - 87,711,435 (+)	NCBI
Celera	10	82,606,486 - 82,619,800 (+)	NCBI		Celera
Cytogenetic Map	10	q31	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

COVID-19 (ISO)

genetic disease (ISO)

hepatocellular carcinoma (ISO)

hypertrophic cardiomyopathy 25 (ISO)

Meier-Gorlin syndrome (ISO)

Meier-Gorlin syndrome 5 (ISO)

microcephaly (ISO)

polycystic ovary syndrome (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-citrinin (ISO)

(-)-demecolcine (ISO)

(S)-colchicine (ISO)

(S)-nicotine (ISO)

1,1-dichloroethene (ISO)

1-chloro-2,4-dinitrobenzene (ISO)

17alpha-ethynylestradiol (ISO)

17beta-estradiol (EXP,ISO)

17beta-hydroxy-17-methylestra-4,9,11-trien-3-one (ISO)

2,2',4,4',5,5'-hexachlorobiphenyl (ISO)

2,2',5,5'-tetrachlorobiphenyl (EXP,ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,3,7,8-Tetrachlorodibenzofuran (EXP)

2,4-diaminotoluene (ISO)

2-butoxyethanol (ISO)

3-methylcholanthrene (ISO)

4,4'-diaminodiphenylmethane (ISO)

4,4'-sulfonyldiphenol (ISO)

4-(ethoxymethylene)-2-phenyloxazol-5-one (ISO)

4-nitrophenol (ISO)

5-fluorouracil (ISO)

5-formyltetrahydrofolic acid (ISO)

6-propyl-2-thiouracil (EXP)

acetamide (EXP)

acrylamide (ISO)

adenine (ISO)

afimoxifene (ISO)

aflatoxin B1 (EXP,ISO)

all-trans-retinoic acid (ISO)

amitrole (EXP)

ammonium chloride (EXP)

antimycin A (ISO)

arsenous acid (ISO)

atrazine (EXP)

atropine (ISO)

azathioprine (ISO)

benzalkonium chloride (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

benzoates (ISO)

bicalutamide (ISO)

bisphenol A (EXP,ISO)

caffeine (ISO)

calcitriol (ISO)

cannabidiol (ISO)

carbamazepine (ISO)

carbon nanotube (ISO)

cefaloridine (EXP)

cetylpyridinium (ISO)

CGP 52608 (ISO)

chlorpyrifos (ISO)

choline (ISO)

cisplatin (ISO)

cobalt dichloride (ISO)

colforsin daropate hydrochloride (ISO)

copper atom (ISO)

copper(0) (ISO)

coumestrol (ISO)

cryptolepine (ISO)

cyclosporin A (ISO)

deguelin (ISO)

diarsenic trioxide (ISO)

diazinon (EXP)

dibutyl phthalate (ISO)

diclofenac (ISO)

dieldrin (EXP)

dioxygen (ISO)

disodium selenite (ISO)

diuron (ISO)

doxorubicin (ISO)

endosulfan (ISO)

Enterolactone (ISO)

ethyl methanesulfonate (ISO)

etoposide (ISO)

fluoranthene (ISO)

folic acid (ISO)

furan (EXP)

gamma-tocopherol (ISO)

genistein (ISO)

gentamycin (EXP)

glyphosate (ISO)

GW 4064 (ISO)

ketamine (EXP)

L-ascorbic acid (ISO)

L-methionine (ISO)

Lasiocarpine (ISO)

lead diacetate (ISO)

lidocaine (EXP)

lipopolysaccharide (ISO)

lithium chloride (ISO)

lucanthone (ISO)

LY294002 (ISO)

metacetamol (ISO)

methimazole (EXP)

methyl methanesulfonate (ISO)

methylseleninic acid (ISO)

mitomycin C (ISO)

N-(6-acetamidohexyl)acetamide (ISO)

N-methyl-4-phenylpyridinium (ISO)

N-nitrosodiethylamine (ISO)

N-nitrosodimethylamine (ISO)

niclosamide (ISO)

nicotine (ISO)

ochratoxin A (ISO)

ozone (ISO)

paracetamol (EXP,ISO)

parathion (ISO)

PCB138 (EXP,ISO)

phenethyl isothiocyanate (ISO)

phenobarbital (ISO)

phytoestrogen (ISO)

picoxystrobin (ISO)

pirinixic acid (ISO)

piroxicam (ISO)

pravastatin (EXP,ISO)

progesterone (ISO)

PX-866 (ISO)

quercetin (ISO)

quinolin-8-ol (ISO)

raloxifene (ISO)

resveratrol (ISO)

rotenone (ISO)

SB 203580 (ISO)

silicon dioxide (ISO)

silver(1+) nitrate (ISO)

simvastatin (ISO)

succimer (ISO)

sulfadimethoxine (EXP)

sunitinib (ISO)

tamibarotene (ISO)

tamoxifen (ISO)

tebufenpyrad (ISO)

testosterone (ISO)

tetrachloromethane (ISO)

thioacetamide (EXP)

tocopherol (ISO)

toluene 2,4-diisocyanate (ISO)

trichostatin A (ISO)

triclosan (ISO)

trimellitic anhydride (ISO)

troglitazone (ISO)

tropan-3alpha-yl 3-hydroxy-2-phenylpropanoate (ISO)

valproic acid (ISO)

vinclozolin (EXP)

vincristine (ISO)

zaragozic acid A (EXP,ISO)

zearalenone (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cell division (IEA)

cellular response to angiotensin (IEP)

cellular response to vasopressin (IEP)

DNA replication initiation (IEA)

mitotic DNA replication checkpoint signaling (IBA)

positive regulation of chromosome segregation (ISO)

positive regulation of cyclin-dependent protein serine/threonine kinase activity (IMP)

positive regulation of cytokinesis (ISO)

positive regulation of fibroblast proliferation (IDA)

regulation of mitotic metaphase/anaphase transition (ISO)

Cellular Component

cytoplasm (ISO)

cytosol (IEA,ISO)

intercellular bridge (IEA,ISO)

mitotic spindle (IEA,ISO)

nucleolus (ISO)

nucleoplasm (IEA,ISO)

nucleus (IBA,ISO)

spindle (ISO)

spindle midzone (ISO)

spindle pole (ISO)

Molecular Function

ATP hydrolysis activity (IEA)

chromatin binding (ISO)

kinase binding (ISO)

protein binding (IPI,ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

cell cycle pathway, mitotic (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Differences in E2F subunit expression in quiescent and proliferating vascular smooth muscle cells.	Fujita N, etal., Am J Physiol Heart Circ Physiol 2002 Jul;283(1):H204-12.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	ATP-dependent activation of p21WAF1/CIP1-associated Cdk2 by Cdc6.	Kan Q, etal., Proc Natl Acad Sci U S A. 2008 Mar 25;105(12):4757-62. doi: 10.1073/pnas.0706392105. Epub 2008 Mar 20.
4.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
5.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
6.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
7.	GOA pipeline	RGD automated data pipeline
8.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
10.	Comprehensive gene review and curation	RGD comprehensive gene curation
11.	Cdc6 protein activates p27KIP1-bound Cdk2 protein only after the bound p27 protein undergoes C-terminal phosphorylation.	Uranbileg B, etal., J Biol Chem. 2012 Feb 24;287(9):6275-83. doi: 10.1074/jbc.M111.318295. Epub 2012 Jan 5.

Additional References at PubMed

PMID:14667810	PMID:20466002	PMID:21041660	PMID:21383955	PMID:22581055	PMID:26899166

Genomics

Comparative Map Data

Cdc6
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	10	83,864,189 - 83,878,011 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	83,864,638 - 83,878,011 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	10	88,808,558 - 88,821,905 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	88,306,636 - 88,320,009 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	83,699,232 - 83,712,599 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	86,819,477 - 86,833,301 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	86,819,472 - 86,833,402 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	10	86,614,443 - 86,628,265 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	10	87,684,493 - 87,697,865 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	10	87,699,352 - 87,711,435 (+)	NCBI
Celera	10	82,606,486 - 82,619,800 (+)	NCBI		Celera
Cytogenetic Map	10	q31	NCBI

CDC6
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	17	40,287,879 - 40,304,657 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	17	40,287,879 - 40,304,657 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	17	38,444,131 - 38,460,909 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	17	35,697,672 - 35,712,939 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	17	35,697,671 - 35,712,939	NCBI
Celera	17	35,104,288 - 35,119,555 (+)	NCBI		Celera
Cytogenetic Map	17	q21.2	NCBI
HuRef	17	34,237,430 - 34,252,580 (+)	NCBI		HuRef
CHM1_1	17	38,679,451 - 38,694,721 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	17	41,151,103 - 41,168,161 (+)	NCBI		T2T-CHM13v2.0

Cdc6
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	98,798,627 - 98,814,768 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	11	98,798,627 - 98,814,766 (+)	Ensembl		GRCm39 Ensembl
GRCm38	11	98,907,709 - 98,923,942 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	98,907,801 - 98,923,940 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	11	98,769,203 - 98,785,256 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	11	98,723,979 - 98,740,032 (+)	NCBI		MGSCv36	mm8
Celera	11	108,572,996 - 108,589,050 (+)	NCBI		Celera
Cytogenetic Map	11	D	NCBI
cM Map	11	62.74	NCBI

Cdc6
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955451	14,860,309 - 14,871,494 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955451	14,857,174 - 14,871,324 (+)	NCBI	ChiLan1.0	ChiLan1.0

CDC6
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1	17	26,548,396 - 26,563,182 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	17	16,987,721 - 17,002,488 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	17	17,211,681 - 17,225,972 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	17	17,211,681 - 17,225,972 (-)	Ensembl	panpan1.1		panPan2

CDC6
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	9	22,303,549 - 22,317,046 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	9	22,226,719 - 22,316,963 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	9	21,775,702 - 21,789,360 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	9	23,095,961 - 23,109,590 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	9	23,096,449 - 23,109,464 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	9	21,870,059 - 21,883,679 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	9	22,128,778 - 22,142,399 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	9	22,253,668 - 22,267,326 (-)	NCBI		UU_Cfam_GSD_1.0

Cdc6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	21,704,070 - 21,715,635 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936490	15,360,504 - 15,370,008 (+)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936490	15,360,477 - 15,370,519 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CDC6
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	12	22,101,282 - 22,118,593 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	12	22,101,281 - 22,118,441 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	12	22,408,460 - 22,425,011 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

CDC6
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	16	65,873,341 - 65,888,180 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	16	65,871,627 - 65,888,217 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666077	36,774,514 - 36,789,637 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Cdc6
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624795	2,980,185 - 2,992,330 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624795	2,980,334 - 2,992,579 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Cdc6
62 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	84
Count of miRNA genes:	71
Interacting mature miRNAs:	79
Transcripts:	ENSRNOT00000038228
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
61427	Cia16	Collagen induced arthritis QTL 16	3.2		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	6357896	96121100	Rat
2303118	Mamtr7	Mammary tumor resistance QTL 7		0.003	mammary gland integrity trait (VT:0010552)	mammary tumor growth rate (CMO:0000344)	10	9658275	104670812	Rat
2301967	Cm73	Cardiac mass QTL 73	4.55		heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	10	14487011	89062041	Rat
631268	Cia21	Collagen induced arthritis QTL 21	3.1		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	14487011	104060283	Rat
2316949	Gluco60	Glucose level QTL 60	3.7		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	10	14487011	107057807	Rat
1554317	Bmd4	Bone mineral density QTL 4	9.4	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	10	19816042	99406971	Rat
724556	Pur2	Proteinuria QTL 2	5.5		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	10	22427500	90627625	Rat
61354	Pia10	Pristane induced arthritis QTL 10		0.01	joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	23444813	104060283	Rat
631267	Cia20	Collagen induced arthritis QTL 20	3.2		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	23444813	104060283	Rat
61325	Aia5	Adjuvant induced arthritis QTL 5		0.01	joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	23444813	104060283	Rat
1298069	Bp168	Blood pressure QTL 168	5.5		blood pressure trait (VT:0000183)	systolic blood pressure (CMO:0000004)	10	26521957	98003205	Rat
631542	Bp82	Blood pressure QTL 82	6.8		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	26521957	98952741	Rat
1331791	Cm31	Cardiac mass QTL 31	3.84606		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	10	29299504	107211142	Rat
1576308	Schws1	Schwannoma susceptibility QTL 1		0.0041	nervous system integrity trait (VT:0010566)	percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)	10	40035094	102359817	Rat
631269	Cia22	Collagen induced arthritis QTL 22	8.9		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	40035094	104060283	Rat
631270	Cia23	Collagen induced arthritis QTL 23	3.9		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	40035094	104060283	Rat
631552	Vetf2	Vascular elastic tissue fragility QTL 2	4.5	0.0002	aorta elastic tissue integrity trait (VT:0010556)	artery internal elastic lamina non-tumorous lesion count (CMO:0001913)	10	41142633	86142633	Rat
61463	Bp12	Blood pressure QTL 12	6.3	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	41333258	86333258	Rat
1298078	Stresp5	Stress response QTL 5	2.99	0.00025	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	10	42045676	104670812	Rat
70188	BpQTLcluster1	Blood pressure QTL cluster 1	4.864		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	1	42323132	87323132	Rat
70188	BpQTLcluster1	Blood pressure QTL cluster 1	4.864		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	42323132	87323132	Rat
70188	BpQTLcluster1	Blood pressure QTL cluster 1	4.864		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	42323132	87323132	Rat
70188	BpQTLcluster1	Blood pressure QTL cluster 1	4.864		arterial blood pressure trait (VT:2000000)	pulse pressure (CMO:0000292)	1	42323132	87323132	Rat
70198	BpQTLcluster9	Blood pressure QTL cluster 9	2.94		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	42323132	87323132	Rat
9589030	Epfw9	Epididymal fat weight QTL 9	19.24	0.001	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	10	44441699	89441699	Rat
7411614	Foco18	Food consumption QTL 18		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	10	44441699	89441699	Rat
8694173	Bw149	Body weight QTL 149	4.38	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	10	44441699	89441699	Rat
2300218	Hpcl2	Hepatic cholesterol level QTL 2			liver cholesterol amount (VT:0010498)	liver cholesterol level (CMO:0001597)	10	45029650	95600334	Rat
631547	Bp87	Blood pressure QTL 87	4.5		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	47369470	92369470	Rat
1549846	Scl47	Serum cholesterol level QTL 47	3.6		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	10	50574707	95574707	Rat
70364	Bp72	Blood pressure QTL 72			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	51121100	96121100	Rat
61387	Bp1	Blood pressure QTL 1	5.1		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	51770177	107211142	Rat
61387	Bp1	Blood pressure QTL 1	5.1		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	10	51770177	107211142	Rat
1359017	Hrtrt21	Heart rate QTL 21	2.4		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	10	51772940	96772940	Rat
631530	Tls3	T-lymphoma susceptibility QTL 3	0	0.0001	thymus integrity trait (VT:0010555)	percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)	10	51774612	95600334	Rat
631535	Cm51	Cardiac mass QTL 51	3		heart mass (VT:0007028)	calculated heart weight (CMO:0000073)	10	51786282	91669536	Rat
70171	Cari1	Carrageenan-induced inflammation QTL 1	4.9	0.0005	hypodermis integrity trait (VT:0010550)	inflammatory exudate volume (CMO:0001429)	10	53797385	107211142	Rat
70164	Bw21	Body weight QTL 21	4.36	0.00005	body mass (VT:0001259)	body weight (CMO:0000012)	10	53797494	98952626	Rat
1354608	Cm33	Cardiac mass QTL 33	2.8		heart left ventricle mass (VT:0007031)	heart left ventricle wet weight (CMO:0000071)	10	54809292	99809292	Rat
2312662	Slep8	Serum leptin concentration QTL 8		0.05	blood leptin amount (VT:0005667)	serum leptin level (CMO:0000780)	10	57134272	102134272	Rat
2312668	Scl65	Serum cholesterol level QTL 65		0.001	blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	10	57134272	102134272	Rat
2312672	Insul15	Insulin level QTL 15		0.01	blood insulin amount (VT:0001560)	serum insulin level (CMO:0000358)	10	57134272	102134272	Rat
1549831	Bss6	Bone structure and strength QTL 6	4		lumbar vertebra strength trait (VT:0010574)	vertebra ultimate force (CMO:0001678)	10	57576521	102576521	Rat
2293698	Bss43	Bone structure and strength QTL 43	5.33	0.0001	lumbar vertebra size trait (VT:0010518)	lumbar vertebra cross-sectional area (CMO:0001689)	10	59209888	104209888	Rat
2306970	Anxrr22	Anxiety related response QTL 22	5.95		fear/anxiety-related behavior trait (VT:1000241)	number of periods of voluntary immobility (CMO:0001045)	10	61345276	98211570	Rat
6893336	Cm75	Cardiac mass QTL 75	0.1	0.87	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	10	61345276	99703528	Rat
1558643	Cm44	Cardiac mass QTL 44	4.8	0.0000368	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	10	61345276	99703528	Rat
2313103	Bss80	Bone structure and strength QTL 80	2	0.0001	tibia strength trait (VT:1000284)	tibia midshaft endosteal cross-sectional area (CMO:0001716)	10	62057807	107057807	Rat
2313105	Bss79	Bone structure and strength QTL 79	1.8	0.0001	tibia size trait (VT:0100001)	tibia midshaft cross-sectional area (CMO:0001717)	10	62057807	107057807	Rat
61449	Ciaa2	CIA Autoantibody QTL 2	7.1		blood autoantibody amount (VT:0003725)	calculated serum anti-type 2 collagen antibody titer (CMO:0001279)	10	63221094	107211142	Rat
1357344	Bp249	Blood pressure QTL 249		0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	66743655	98003205	Rat
2317029	Aia19	Adjuvant induced arthritis QTL 19	2.98		joint integrity trait (VT:0010548)	left rear ankle joint diameter (CMO:0002149)	10	66978955	107211142	Rat
2317039	Aia6	Adjuvant induced arthritis QTL 6	4.31		joint integrity trait (VT:0010548)	right rear ankle joint diameter (CMO:0002150)	10	66978955	107211142	Rat
10450498	Bp384	Blood pressure QTL 384		0.002	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	67750049	107211142	Rat
1642980	Bp300	Blood pressure QTL 300			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	68383129	107211142	Rat
61396	Bp9	Blood pressure QTL 9	4.8	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	68420376	107211142	Rat
2300172	Bmd57	Bone mineral density QTL 57	9.8	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	10	69738412	107211142	Rat
2293646	Bss25	Bone structure and strength QTL 25	10.96	0.0001	femur morphology trait (VT:0000559)	femur cross-sectional area (CMO:0001661)	10	69738412	107211142	Rat
2293663	Bss33	Bone structure and strength QTL 33	9.34	0.0001	femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	10	69738412	107211142	Rat
6893366	Bw106	Body weight QTL 106	0.3	0.47	body mass (VT:0001259)	body weight (CMO:0000012)	10	70199100	107211142	Rat
70193	Mcs7	Mammary carcinoma susceptibility QTL 7	2.38		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	10	72224939	107211142	Rat
2298548	Neuinf7	Neuroinflammation QTL 7	3.4		nervous system integrity trait (VT:0010566)	spinal cord RT1-B protein level (CMO:0002132)	10	72224939	107211142	Rat
2306793	Ean5	Experimental allergic neuritis QTL 5	4.7		nervous system integrity trait (VT:0010566)	IFNG-secreting splenocyte count (CMO:0002122)	10	72552416	93995749	Rat
1358188	Ept9	Estrogen-induced pituitary tumorigenesis QTL 9	3.9		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	10	73453136	96120911	Rat
2292617	Ept18	Estrogen-induced pituitary tumorigenesis QTL 18	3.9		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	10	73453136	96120911	Rat
12880050	Am10	Aortic mass QTL 10		0.016	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	10	74372084	84007272	Rat
1579919	Bp281	Blood pressure QTL 281		0.01	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	74372084	94965338	Rat
631537	Oia4	Oil induced arthritis QTL 4			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	75631887	87055282	Rat
2325836	Bp346	Blood pressure QTL 346		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	76246085	84007272	Rat
10450495	Bp383	Blood pressure QTL 383		0.002	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	76246085	94965338	Rat
2292438	Bp311	Blood pressure QTL 311			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	76246085	107211142	Rat
1302404	Cia27	Collagen induced arthritis QTL 27	2.6	0.0045	joint integrity trait (VT:0010548)	experimental arthritis severity measurement (CMO:0001459)	10	76452683	107211142	Rat
4889492	Pancm2	Pancreatic morphology QTL 2	3.2		pancreatic beta cell morphology trait (VT:0005217)	ratio of insulin-positive cell area to total area of splenic region of pancreas (CMO:0001814)	10	76748906	107211142	Rat
724516	Uae17	Urinary albumin excretion QTL 17	3.6		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	10	78210622	85220348	Rat
1300107	Rf18	Renal function QTL 18	3.41		urine output (VT:0003620)	timed urine volume (CMO:0000260)	10	78775516	98279596	Rat
1358915	Stresp7	Stress response QTL 7	3.52		blood norepinephrine amount (VT:0005663)	plasma norepinephrine level (CMO:0001010)	10	78899655	87307728	Rat
634354	Rends3	Renal damage susceptibility QTL 3		0.05	kidney blood vessel morphology trait (VT:0000530)	organ lesion measurement (CMO:0000677)	10	79813789	85160854	Rat
631555	Bp134	Blood pressure QTL 134		0.001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	80515287	91230079	Rat
6893357	Bw102	Body weight QTL 102	0.5	0.36	body mass (VT:0001259)	body weight (CMO:0000012)	10	80515287	101325465	Rat
2303589	Bw87	Body weight QTL 87	2		body mass (VT:0001259)	body weight (CMO:0000012)	10	81285008	107211142	Rat
4889948	Bss91	Bone structure and strength QTL 91	4		tibia area (VT:1000281)	tibia midshaft total cross-sectional area (CMO:0001715)	10	82564856	92369470	Rat
2317754	Glom25	Glomerulus QTL 25	3.5		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	10	82685200	107211142	Rat

Markers in Region

RH143256

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	10	83,861,280 - 83,861,473 (+)	MAPPER	mRatBN7.2
Rnor_6.0	10	86,816,573 - 86,816,765	NCBI	Rnor6.0
Rnor_5.0	10	86,611,536 - 86,611,728	UniSTS	Rnor5.0
RGSC_v3.4	10	87,681,137 - 87,681,329	UniSTS	RGSC3.4
Celera	10	82,603,143 - 82,603,323	UniSTS
RH 3.4 Map	10	860.3	UniSTS
Cytogenetic Map	10	q31	UniSTS

BI286604

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	10	83,859,552 - 83,859,731 (+)	MAPPER	mRatBN7.2
Rnor_6.0	10	86,814,846 - 86,815,024	NCBI	Rnor6.0
Rnor_5.0	10	86,609,809 - 86,609,987	UniSTS	Rnor5.0
RGSC_v3.4	10	87,679,410 - 87,679,588	UniSTS	RGSC3.4
Celera	10	82,601,416 - 82,601,594	UniSTS
RH 3.4 Map	10	856.2	UniSTS
Cytogenetic Map	10	q31	UniSTS

AW529160

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	10	83,859,874 - 83,860,119 (+)	MAPPER	mRatBN7.2
Rnor_6.0	10	86,815,168 - 86,815,412	NCBI	Rnor6.0
Rnor_5.0	10	86,610,131 - 86,610,375	UniSTS	Rnor5.0
RGSC_v3.4	10	87,679,732 - 87,679,976	UniSTS	RGSC3.4
Celera	10	82,601,738 - 82,601,982	UniSTS
RH 3.4 Map	10	837.89	UniSTS
Cytogenetic Map	10	q31	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	2	24	28	22	13	22			20	16	26
Low	1	12	16	9	6	9	2	3	40	15	15	11	2
Below cutoff		7	13	10		10	6	8	14	4			6

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001108298	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006247354	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006247355	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC141969	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473948	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ233913	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000220	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000038228 ⟹ ENSRNOP00000032177

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	10	83,864,638 - 83,878,011 (+)	Ensembl
Rnor_6.0 Ensembl	10	86,819,929 - 86,833,301 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000081424 ⟹ ENSRNOP00000071363

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	10	86,819,472 - 86,833,402 (+)	Ensembl

RefSeq Acc Id:

NM_001108298 ⟹ NP_001101768

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	10	83,864,638 - 83,878,011 (+)	NCBI
Rnor_6.0	10	86,819,929 - 86,833,301 (+)	NCBI
Rnor_5.0	10	86,614,443 - 86,628,265 (+)	NCBI
RGSC_v3.4	10	87,684,493 - 87,697,865 (+)	RGD
Celera	10	82,606,486 - 82,619,800 (+)	RGD

Sequence:

show sequence

TGTGGAGTGCTGGCTAGTTCTGTGCAGGGGAGGACGGAGCTGCACTGCCTGGACTTGGGAGAGC
CTAAATGTCTGGAACTAAACTAGTGCTAAAGACGTCTCGCATGTCTGGAGTGAAGGAACTAGAA
GTATTATAGAAATTACTGGAGATAAACTTCTGGCATCGCTCAAGTTTGTGTGGCCATCATGCCT
CAAACCCGATCCCAGACACAAGCTACCATCGACTTTCCGAAAAAGAAGCAATCTAAGACCCTGA
GCAAGACAAACTCCCGTGACAGTGAAGTAAAACTTAGAAACGTCCAGCCTGTACCCACCACTCC
GTGTGCGGACATAAAAATTCTGCCTCTCAGTCCCCGAAAACGTTTGGGTGATGACAATCTGTGC
AACACTCCCCATTTATCTCCATGTTCTCCGCCCAAGCTGGGCAGGAAGGAAAACGGCCCCCCTC
GCTCACATACACGGAAGGGATGCAGATTAATATTCGATGATGAGCTGGCAGTTAAGGCTTCCGC
CCCAAAAGAACAAGACAGAGTTCCCCAGCACCAAATACTTTCCTCCGCTCAAAGAGGTCAAGAG
AGCGAAACAAATCCTGAGCAGAAATGCCCACCAGAGAAGGAATCCGCGTGTATGCGACTGTTCA
AGCAGGAAGGCACTTGCTATCAACAGGCAAAGCTTGTCCTGAATACAGCTGTCCCGGACCGGCT
GCCTGCCAGAGAACAGGAGATGGGTGTCATCAGGGATTTCCTGAAGGAGCACATCTGTGGGAAA
AAAGCTGGGAGTCTCTACCTTTCTGGCGCTCCTGGAACTGGGAAAACTGCCTGTTTAAGCCGGA
TTCTGCAGGACTTCAAGAAGGAAGTGAAAGGCTTTAAAACTATCGTGCTGAATTGCATGTCCCT
GAGGAACGCTCAGGCCGTGTTCCCAGCCATTGCTCAGGAGATTGGTCGGGAGGAACTCTGCAGA
CCCACCGGGAAGGACTTGATGAGAAAGCTGGAAAAGCACTTGACAGCCGAGAGGGGCCCCATGA
TTGTGTTGGTGTTGGACGAGATGGATCAGCTGGACAGCAAAGGGCAGGATGTGTTATACACCCT
GTTTGAGTGGCCGTGGTTAAGCAATTCCCGATTGGTGCTCATTGGTATTGCTAATACCCTGGAT
CTCACGGACAGAATTCTGCCGAGACTTGAAGCTAGAGAAGGCTGTAAGCCGAAGCTACTGAACT
TCCCACCTTACACCAGGAATCAGATAGCTGCGATCTTGCAGGATAGGCTTAGTCAGGTATCAAA
AGACCAGGTTCTGGACAGTGCTGCGATTCAGTTCTGTGCCCGCAAAGTATCTGCTGTCTCAGGG
GACATCCGGAAAGCGCTGGATGTTTGCAGGCGAGCTATTGAAATTGTGGAGTCGGATGTCAGGA
GCCAGACAGTCCTCAAACCACTCTCCGAATGTAAATCACCCTGCGAGTCGCTGGTTCCCAAGCG
TGTCGGTCTCGCTCACATATCCCAAGTCATTTCGGGAGTTGATGGTAACAGGGTGACTTTGAGC
CAAGAAAACACACAGGATTCCCTTCCTCTCCAGCAGAAGATCTTGGTTTGCTCTTTGCTGCTCT
TGACCAAGCGGCTAAAAATCAAAGAGGTCACCCTGGGGAAGTTATATGAAGCCTACAGTAGTGT
CTGTCGTAAACAGCAGGTGGCAGCCGTAGACCAGTCTGAGTGTTTGTCCCTTTCTGGACTCCTG
GAATCCAGGGGCATTGTGGGACTGAAGAAAAACAAGGAGAGCCGCCTCACCAAGGTGTCTCTGA
AGATTGAAGAAAAGGAGATAGAGCATGTCCTAAAAGGCAAAGCTTTCATTGGGAACATCCTCGC
TGCCGGGCTGCCCTGAACGGTTCTCTTCCTTAGGGCACCTGCAAGCGTCCTGCTGGCGTTTGCA
GCTCGGGGGAGTCTTCGTTTTAGTAAGGTCGTTCGGAAACAGTTAACGGCCTTTTTTACTCCGC
ACCAGTAAATTTTAGTGTATGAATTCCTGAGTGTTAGCACTGGCTAATGTCCTTGGCTCTTACT
GTTTTTACCCATAAAAATGACCGAGTGCTGGGTGTGATGGCGGATGCCTGTGCTCCCAGCACTT
GGGAAACAGAGTCAGGAGTTCAAGGCCATCCTTTGCTACACAGTGAGTTTGAGCTAGCCCGGAC
TACACAAGACTGTAAAAAGTAAAAGCAGGGCTGGGGATTTAGCTCAGTGGTAGAGCGCTTACCT
AGGAAGCGCAAGGCCCTGGGTTCGGTCCCCAGCTCCGAAAAAAAAAGAACCAAAAAAAAAAAAA
AAAAGTAAAAGCAATGACCCCTTTTAAAGCAACATTCAGTACTTTTCCCTTCCTGACCACGGTA
CCTGCAAGTGTGTACAGACTTGTGTTGAAGAATTCGTATGTATATTACCTCTGTCTACAAAGGG
TGTGTTTTGTAAAGAACTTTGAGGTTTAGAAAGATGAAACGGAATGATCCAGAAAAATACACAA
GCCTACATGGGAAACACAAAGGACATTTTGTGCAGAGGACGCTCCATACATGTGACAGGTGCTG
CCGCACCGGACTTTCTAAAGACGGGTGGACGATTCTCCAGCGCTCCCCACCAGTATGGGGGTGA
CAAGGAGAGTGTAACTACAGATTGTGAATATATTTATTTTCAAGTTTG

hide sequence

RefSeq Acc Id:

XM_006247354 ⟹ XP_006247416

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	10	83,864,190 - 83,878,011 (+)	NCBI
Rnor_6.0	10	86,819,478 - 86,833,301 (+)	NCBI
Rnor_5.0	10	86,614,443 - 86,628,265 (+)	NCBI

Sequence:

show sequence

TGGGTGTGACTTCGTGTTGGGCGCTGAGACCTGGGGCTGTCCCTATTGGCTGCCAACTGCCACC
GGCGAAGGCGTGGTGATTAGTGACAACTAATCAGAAGCCTGGCTGGGCTTTGGCGGGAGAGGAG
AACGCTGAGGTGGAGCGAATTTGGCGCGAGCTGACTTTGCAGCAGCTGTGGACCTTGTGGCCGG
AGAGTCCTTGCGGTTCTGATCGAGATCAGGGGAGCGTGCACTGAGCGACACATTCCTGAAGAGT
GCAAAGCTCCGTGAGTTGTGTGGCCATCATGCCTCAAACCCGATCCCAGACACAAGCTACCATC
GACTTTCCGAAAAAGAAGCAATCTAAGACCCTGAGCAAGACAAACTCCCGTGACAGTGAAGTAA
AACTTAGAAACGTCCAGCCTGTACCCACCACTCCGTGTGCGGACATAAAAATTCTGCCTCTCAG
TCCCCGAAAACGTTTGGGTGATGACAATCTGTGCAACACTCCCCATTTATCTCCATGTTCTCCG
CCCAAGCTGGGCAGGAAGGAAAACGGCCCCCCTCGCTCACATACACGGAAGGGATGCAGATTAA
TATTCGATGATGAGCTGGCAGTTAAGGCTTCCGCCCCAAAAGAACAAGACAGAGTTCCCCAGCA
CCAAATACTTTCCTCCGCTCAAAGAGGTCAAGAGAGCGAAACAAATCCTGAGCAGAAATGCCCA
CCAGAGAAGGAATCCGCGTGTATGCGACTGTTCAAGCAGGAAGGCACTTGCTATCAACAGGCAA
AGCTTGTCCTGAATACAGCTGTCCCGGACCGGCTGCCTGCCAGAGAACAGGAGATGGGTGTCAT
CAGGGATTTCCTGAAGGAGCACATCTGTGGGAAAAAAGCTGGGAGTCTCTACCTTTCTGGCGCT
CCTGGAACTGGGAAAACTGCCTGTTTAAGCCGGATTCTGCAGGACTTCAAGAAGGAAGTGAAAG
GCTTTAAAACTATCGTGCTGAATTGCATGTCCCTGAGGAACGCTCAGGCCGTGTTCCCAGCCAT
TGCTCAGGAGATTGGTCGGGAGGAACTCTGCAGACCCACCGGGAAGGACTTGATGAGAAAGCTG
GAAAAGCACTTGACAGCCGAGAGGGGCCCCATGATTGTGTTGGTGTTGGACGAGATGGATCAGC
TGGACAGCAAAGGGCAGGATGTGTTATACACACTGTTTGAGTGGCCGTGGTTAAGCAATTCCCG
ATTGGTGCTCATTGGTATTGCTAATACCCTGGATCTCACGGACAGAATTCTGCCGAGACTTGAA
GCTAGAGAAGGCTGTAAGCCGAAGCTACTGAACTTCCCACCTTACACCAGGAATCAGATAGCTG
CGATCTTGCAGGATAGGCTTAGTCAGGTATCAAAAGACCAGGTTCTGGACAGTGCTGCGATTCA
GTTCTGTGCCCGCAAAGTATCTGCTGTCTCAGGGGACATCCGGAAAGCGCTGGATGTTTGCAGG
CGAGCTATTGAAATTGTGGAGTCGGATGTCAGGAGCCAGACAGTCCTCAAACCACTCTCCGAAT
GTAAATCACCCTGCGAGTCGCTGGTTCCCAAGCGTGTCGGTCTCGCTCACATATCCCAAGTCAT
TTCGGGAGTTGATGGTAACAGGGTGACTTTGAGCCAAGAAAACACACAGGATTCCCTTCCTCTC
CAGCAGAAGATCTTGGTTTGCTCTTTGCTGCTCTTGACCAAGCGGCTAAAAATCAAAGAGGTCA
CCCTGGGGAAGTTATATGAAGCCTACAGTAGTGTCTGTCGTAAACAGCAGGTGGCAGCCGTAGA
CCAGTCTGAGTGTTTGTCCCTTTCTGGACTCCTGGAATCCAGGGGCATTGTGGGACTGAAGAAA
AACAAGGAGAGCCGCCTCACCAAGGTGTCTCTGAAGATTGAAGAAAAGGAGATAGAGCATGTCC
TAAAAGGCAAAGCTTTCATTGGGAACATCCTCGCTGCCGGGCTGCCCTGAACGGTTCTCTTCCT
TAGGGCACCTGCAAGCGTCCTGCTGGCGTTTGCAGCTCGGGGGAGTCTTCGTTTTAGTAAGGTC
GTTCGGAAACAGTTAACGGCCTTTTTTACTCCGCACCAGTAAATTTTAGTGTATGAATTCCTGA
GTGTTAGCACTGGCTAATGTCCTTGGCTCTTACTGTTTTTACCCATAAAAATGACCGAGTGCTG
GGTGTGATGGCGGATGCCTGTGCTCCCAGCACTTGGGAAACAGAGTCAGGAGTTCAAGGCCATC
CTTTGCTACACAGTGAGTTTGAGCTAGCCCGGACTACACAAGACTGTAAAAAGTAAAAGCAGGG
CTGGGGATTTAGCTCAGTGGTAGAGCGCTTACCTAGGAAGCGCAAGGCCCTGGGTTCGGTCCCC
AGCTCCGAAAAAAAAAGAACCAAAAAAAAAAAAAAAAAGTAAAAGCAATGACCCCTTTTAAAGC
AACATTCAGTACTTTTCCCTTCCTGACCACGGTACCTGCAAGTGTGTACAGACTTGTGTTGAAG
AATTCGTATGTATATTACCTCTGTCTACAAAGGGTGTGTTTTGTAAAGAACTTTGAGGTTTAGA
AAGATGAAACGGAATGATCCAGAAAAATACACAAGCCTACATGGGAAACACAAAGGACATTTTG
TGCAGAGGACGCTCCATACATGTGACAGGTGCTGCCGCACCGGACTTTCTAAAGACGGGTGGAC
GATTCTCCAGCGCTCCCCACCAGTATGGGGGTGACAAGGAGAGTGTAACTACAGATTGTGAATA
TATTTATTTTCAAGTTTG

hide sequence

RefSeq Acc Id:

XM_006247355 ⟹ XP_006247417

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	10	83,864,189 - 83,878,011 (+)	NCBI
Rnor_6.0	10	86,819,477 - 86,833,301 (+)	NCBI
Rnor_5.0	10	86,614,443 - 86,628,265 (+)	NCBI

Sequence:

show sequence

GTGGGTGTGACTTCGTGTTGGGCGCTGAGACCTGGGGCTGTCCCTATTGGCTGCCAACTGCCAC
CGGCGAAGGCGTGGTGATTAGTGACAACTAATCAGAAGCCTGGCTGGGCTTTGGCGGGAGAGGA
GAACGCTGAGGTGGAGCGAATTTGGCGCGAGCTGACTTTGCAGCAGCTGTGGACCTTGTGGCCG
GAGAGTCCTTGCGGTTCTGATCGAGATCAGGGGAGCGTGCACTGAGCGACACATTCCTGAAGAG
TGCAAAGCTCCGTGAGTTGTGTGGCCATCATGCCTCAAACCCGATCCCAGACACAAGCTACCAT
CGACTTTCCGAAAAAGAAGCAATCTAAGACCCTGAGCAAGACAAACTCCCGTGACAGTGAAGTA
AAACTTAGAAACGTCCAGCCTGTACCCACCACTCCGTGTGCGGACATAAAAATTCTGCCTCTCA
GTCCCCGAAAACGTTTGGGTGATGACAATCTGTGCAACACTCCCCATTTATCTCCATGTTCTCC
GCCCAAGCTGGGCAGGAAGGAAAACGGCCCCCCTCGCTCACATACACGGAAGGGATGCAGATTA
ATATTCGATGATGAGCTGGCAGTTAAGGCTTCCGCCCCAAAAGAACAAGACAGAGTTCCCCAGC
ACCAAATACTTTCCTCCGCTCAAAGAGGTCAAGAGAGCGAAACAAATCCTGAGCAGAAATGCCC
ACCAGAGAAGGAATCCGCGTGTATGCGACTGTTCAAGCAGGAAGGCACTTGCTATCAACAGGCA
AAGCTTGTCCTGAATACAGCTGTCCCGGACCGGCTGCCTGCCAGAGAACAGGAGATGGGTGTCA
TCAGGGATTTCCTGAAGGAGCACATCTGTGGGAAAAAAGCTGGGAGTCTCTACCTTTCTGGCGC
TCCTGGAACTGGGAAAACTGCCTGTTTAAGCCGGATTCTGCAGGACTTCAAGGAAGTGAAAGGC
TTTAAAACTATCGTGCTGAATTGCATGTCCCTGAGGAACGCTCAGGCCGTGTTCCCAGCCATTG
CTCAGGAGATTGGTCGGGAGGAACTCTGCAGACCCACCGGGAAGGACTTGATGAGAAAGCTGGA
AAAGCACTTGACAGCCGAGAGGGGCCCCATGATTGTGTTGGTGTTGGACGAGATGGATCAGCTG
GACAGCAAAGGGCAGGATGTGTTATACACACTGTTTGAGTGGCCGTGGTTAAGCAATTCCCGAT
TGGTGCTCATTGGTATTGCTAATACCCTGGATCTCACGGACAGAATTCTGCCGAGACTTGAAGC
TAGAGAAGGCTGTAAGCCGAAGCTACTGAACTTCCCACCTTACACCAGGAATCAGATAGCTGCG
ATCTTGCAGGATAGGCTTAGTCAGGTATCAAAAGACCAGGTTCTGGACAGTGCTGCGATTCAGT
TCTGTGCCCGCAAAGTATCTGCTGTCTCAGGGGACATCCGGAAAGCGCTGGATGTTTGCAGGCG
AGCTATTGAAATTGTGGAGTCGGATGTCAGGAGCCAGACAGTCCTCAAACCACTCTCCGAATGT
AAATCACCCTGCGAGTCGCTGGTTCCCAAGCGTGTCGGTCTCGCTCACATATCCCAAGTCATTT
CGGGAGTTGATGGTAACAGGGTGACTTTGAGCCAAGAAAACACACAGGATTCCCTTCCTCTCCA
GCAGAAGATCTTGGTTTGCTCTTTGCTGCTCTTGACCAAGCGGCTAAAAATCAAAGAGGTCACC
CTGGGGAAGTTATATGAAGCCTACAGTAGTGTCTGTCGTAAACAGCAGGTGGCAGCCGTAGACC
AGTCTGAGTGTTTGTCCCTTTCTGGACTCCTGGAATCCAGGGGCATTGTGGGACTGAAGAAAAA
CAAGGAGAGCCGCCTCACCAAGGTGTCTCTGAAGATTGAAGAAAAGGAGATAGAGCATGTCCTA
AAAGGCAAAGCTTTCATTGGGAACATCCTCGCTGCCGGGCTGCCCTGAACGGTTCTCTTCCTTA
GGGCACCTGCAAGCGTCCTGCTGGCGTTTGCAGCTCGGGGGAGTCTTCGTTTTAGTAAGGTCGT
TCGGAAACAGTTAACGGCCTTTTTTACTCCGCACCAGTAAATTTTAGTGTATGAATTCCTGAGT
GTTAGCACTGGCTAATGTCCTTGGCTCTTACTGTTTTTACCCATAAAAATGACCGAGTGCTGGG
TGTGATGGCGGATGCCTGTGCTCCCAGCACTTGGGAAACAGAGTCAGGAGTTCAAGGCCATCCT
TTGCTACACAGTGAGTTTGAGCTAGCCCGGACTACACAAGACTGTAAAAAGTAAAAGCAGGGCT
GGGGATTTAGCTCAGTGGTAGAGCGCTTACCTAGGAAGCGCAAGGCCCTGGGTTCGGTCCCCAG
CTCCGAAAAAAAAAGAACCAAAAAAAAAAAAAAAAAGTAAAAGCAATGACCCCTTTTAAAGCAA
CATTCAGTACTTTTCCCTTCCTGACCACGGTACCTGCAAGTGTGTACAGACTTGTGTTGAAGAA
TTCGTATGTATATTACCTCTGTCTACAAAGGGTGTGTTTTGTAAAGAACTTTGAGGTTTAGAAA
GATGAAACGGAATGATCCAGAAAAATACACAAGCCTACATGGGAAACACAAAGGACATTTTGTG
CAGAGGACGCTCCATACATGTGACAGGTGCTGCCGCACCGGACTTTCTAAAGACGGGTGGACGA
TTCTCCAGCGCTCCCCACCAGTATGGGGGTGACAAGGAGAGTGTAACTACAGATTGTGAATATA
TTTATTTTCAAGTTTG

hide sequence

Protein Sequences


Protein RefSeqs	NP_001101768	(Get FASTA)	NCBI Sequence Viewer
	XP_006247416	(Get FASTA)	NCBI Sequence Viewer
	XP_006247417	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDM05961	(Get FASTA)	NCBI Sequence Viewer
	EDM05962	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001101768 ⟸ NM_001108298

- UniProtKB:

D3ZRK7 (UniProtKB/TrEMBL), A6HIV7 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MPQTRSQTQATIDFPKKKQSKTLSKTNSRDSEVKLRNVQPVPTTPCADIKILPLSPRKRLGDDN
LCNTPHLSPCSPPKLGRKENGPPRSHTRKGCRLIFDDELAVKASAPKEQDRVPQHQILSSAQRG
QESETNPEQKCPPEKESACMRLFKQEGTCYQQAKLVLNTAVPDRLPAREQEMGVIRDFLKEHIC
GKKAGSLYLSGAPGTGKTACLSRILQDFKKEVKGFKTIVLNCMSLRNAQAVFPAIAQEIGREEL
CRPTGKDLMRKLEKHLTAERGPMIVLVLDEMDQLDSKGQDVLYTLFEWPWLSNSRLVLIGIANT
LDLTDRILPRLEAREGCKPKLLNFPPYTRNQIAAILQDRLSQVSKDQVLDSAAIQFCARKVSAV
SGDIRKALDVCRRAIEIVESDVRSQTVLKPLSECKSPCESLVPKRVGLAHISQVISGVDGNRVT
LSQENTQDSLPLQQKILVCSLLLLTKRLKIKEVTLGKLYEAYSSVCRKQQVAAVDQSECLSLSG
LLESRGIVGLKKNKESRLTKVSLKIEEKEIEHVLKGKAFIGNILAAGLP

hide sequence

RefSeq Acc Id:	XP_006247416 ⟸ XM_006247354
- Peptide Label:	isoform X1
- UniProtKB:	D3ZRK7 (UniProtKB/TrEMBL), A6HIV7 (UniProtKB/TrEMBL)
- Sequence:	show sequence MPQTRSQTQATIDFPKKKQSKTLSKTNSRDSEVKLRNVQPVPTTPCADIKILPLSPRKRLGDDN LCNTPHLSPCSPPKLGRKENGPPRSHTRKGCRLIFDDELAVKASAPKEQDRVPQHQILSSAQRG QESETNPEQKCPPEKESACMRLFKQEGTCYQQAKLVLNTAVPDRLPAREQEMGVIRDFLKEHIC GKKAGSLYLSGAPGTGKTACLSRILQDFKKEVKGFKTIVLNCMSLRNAQAVFPAIAQEIGREEL CRPTGKDLMRKLEKHLTAERGPMIVLVLDEMDQLDSKGQDVLYTLFEWPWLSNSRLVLIGIANT LDLTDRILPRLEAREGCKPKLLNFPPYTRNQIAAILQDRLSQVSKDQVLDSAAIQFCARKVSAV SGDIRKALDVCRRAIEIVESDVRSQTVLKPLSECKSPCESLVPKRVGLAHISQVISGVDGNRVT LSQENTQDSLPLQQKILVCSLLLLTKRLKIKEVTLGKLYEAYSSVCRKQQVAAVDQSECLSLSG LLESRGIVGLKKNKESRLTKVSLKIEEKEIEHVLKGKAFIGNILAAGLP hide sequence

RefSeq Acc Id:

XP_006247417 ⟸ XM_006247355

- Peptide Label:

isoform X2

- Sequence:

show sequence

MPQTRSQTQATIDFPKKKQSKTLSKTNSRDSEVKLRNVQPVPTTPCADIKILPLSPRKRLGDDN
LCNTPHLSPCSPPKLGRKENGPPRSHTRKGCRLIFDDELAVKASAPKEQDRVPQHQILSSAQRG
QESETNPEQKCPPEKESACMRLFKQEGTCYQQAKLVLNTAVPDRLPAREQEMGVIRDFLKEHIC
GKKAGSLYLSGAPGTGKTACLSRILQDFKEVKGFKTIVLNCMSLRNAQAVFPAIAQEIGREELC
RPTGKDLMRKLEKHLTAERGPMIVLVLDEMDQLDSKGQDVLYTLFEWPWLSNSRLVLIGIANTL
DLTDRILPRLEAREGCKPKLLNFPPYTRNQIAAILQDRLSQVSKDQVLDSAAIQFCARKVSAVS
GDIRKALDVCRRAIEIVESDVRSQTVLKPLSECKSPCESLVPKRVGLAHISQVISGVDGNRVTL
SQENTQDSLPLQQKILVCSLLLLTKRLKIKEVTLGKLYEAYSSVCRKQQVAAVDQSECLSLSGL
LESRGIVGLKKNKESRLTKVSLKIEEKEIEHVLKGKAFIGNILAAGLP

hide sequence

RefSeq Acc Id:

ENSRNOP00000032177 ⟸ ENSRNOT00000038228

RefSeq Acc Id:

ENSRNOP00000071363 ⟸ ENSRNOT00000081424

Protein Domains

AAA+ ATPase Cdc6 C-terminal

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZRK7-F1-model_v2	AlphaFold	D3ZRK7	1-561	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1309157	AgrOrtholog
BioCyc Gene	G2FUF-23335	BioCyc
Ensembl Genes	ENSRNOG00000027787	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000032177	ENTREZGENE
	ENSRNOP00000032177.4	UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000038228	ENTREZGENE
	ENSRNOT00000038228.5	UniProtKB/TrEMBL
Gene3D-CATH	1.10.10.10	UniProtKB/TrEMBL
	1.10.8.60	UniProtKB/TrEMBL
	3.40.50.300	UniProtKB/TrEMBL
InterPro	AAA_lid_10	UniProtKB/TrEMBL
	ATPase_AAA+_core	UniProtKB/TrEMBL
	Cdc6	UniProtKB/TrEMBL
	Cdc6_C	UniProtKB/TrEMBL
	P-loop_NTPase	UniProtKB/TrEMBL
	WH-like_DNA-bd_sf	UniProtKB/TrEMBL
	WH_DNA-bd_sf	UniProtKB/TrEMBL
KEGG Report	rno:360621	UniProtKB/TrEMBL
NCBI Gene	360621	ENTREZGENE
PANTHER	CELL DIVISION CONTROL PROTEIN 6 HOMOLOG	UniProtKB/TrEMBL
	CELL DIVISION CONTROL PROTEIN 6-RELATED	UniProtKB/TrEMBL
Pfam	AAA_22	UniProtKB/TrEMBL
	AAA_lid_10	UniProtKB/TrEMBL
	Cdc6_C	UniProtKB/TrEMBL
PhenoGen	Cdc6	PhenoGen
PIRSF	Cdc6	UniProtKB/TrEMBL
SMART	AAA	UniProtKB/TrEMBL
	Cdc6_C	UniProtKB/TrEMBL
Superfamily-SCOP	SSF46785	UniProtKB/TrEMBL
	SSF52540	UniProtKB/TrEMBL
UniProt	A6HIV7	ENTREZGENE, UniProtKB/TrEMBL
	D3ZRK7	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2013-01-23	Cdc6	cell division cycle 6	Cdc6	cell division cycle 6 homolog (S. cerevisiae)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	Cdc6	cell division cycle 6 homolog (S. cerevisiae)	Cdc6_predicted	cell division cycle 6 homolog (S. cerevisiae) (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Cdc6_predicted	cell division cycle 6 homolog (S. cerevisiae) (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

Imported Annotations - KEGG (archival)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

Imported Annotations - KEGG (archival)