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Gene: Sp2 (Sp2 transcription factor) Rattus norvegicus

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Symbol:

Sp2

Name:

Sp2 transcription factor

RGD ID:

1592078

Description:

Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and histone deacetylase binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to act upstream of or within several processes, including embryonic organ development; fibroblast proliferation; and in utero embryonic development. Predicted to be located in nucleoplasm. Orthologous to human SP2 (Sp2 transcription factor); INTERACTS WITH 6-propyl-2-thiouracil; acrylamide; amitrole.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

Sp2 transcription factor (mapped); Sp2_mapped; Trans-acting transcription factor 2; transcription factor Sp2

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	SP2 (Sp2 transcription factor)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther
Mus musculus (house mouse):	Sp2 (Sp2 transcription factor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Sp2 (Sp2 transcription factor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	SP2 (Sp2 transcription factor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	SP2 (Sp2 transcription factor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Sp2 (Sp2 transcription factor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	SP2 (Sp2 transcription factor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	SP2 (Sp2 transcription factor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	SP2 (Sp2 transcription factor)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Sp2 (Sp2 transcription factor)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	sp2 (sp2 transcription factor)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	sptf-2	Alliance	DIOPT (PANTHER\|PhylomeDB)
Drosophila melanogaster (fruit fly):	Spps	Alliance	DIOPT (Ensembl Compara\|InParanoid\|PANTHER)
Xenopus tropicalis (tropical clawed frog):	sp2	Alliance	DIOPT (Ensembl Compara\|OMA\|PANTHER\|PhylomeDB)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	82,437,024 - 82,467,583 (-)	NCBI		GRCr8
mRatBN7.2	10	81,940,580 - 81,970,040 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	81,940,587 - 81,970,548 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	10	86,888,604 - 86,913,243 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	86,386,649 - 86,411,284 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	81,779,242 - 81,803,869 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	84,890,930 - 84,920,886 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	84,890,932 - 84,920,886 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	10	84,682,708 - 84,712,592 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	10	85,676,978 - 85,706,042 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	10	80,703,358 - 80,732,335 (-)	NCBI		Celera
Cytogenetic Map	10	q31	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Sp2	Rat	hereditary breast ovarian cancer syndrome		ISO	SP2 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Breast-ovarian cancer more ...	ClinVar	PMID:38922859

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Sp2	Rat	2-methylcholine	affects expression	ISO	SP2 (Homo sapiens)	6480464	beta-methylcholine affects the expression of SP2 mRNA	CTD	PMID:21179406
Sp2	Rat	3,4-methylenedioxymethamphetamine	increases expression	ISO	Sp2 (Mus musculus)	6480464	N-Methyl-3 and 4-methylenedioxyamphetamine results in increased expression of SP2 mRNA	CTD	PMID:20188158
Sp2	Rat	4,4'-diaminodiphenylmethane	decreases expression	ISO	Sp2 (Mus musculus)	6480464	4 and 4'-diaminodiphenylmethane results in decreased expression of SP2 mRNA	CTD	PMID:18648102
Sp2	Rat	4,4'-sulfonyldiphenol	decreases expression	ISO	Sp2 (Mus musculus)	6480464	bisphenol S results in decreased expression of SP2 mRNA	CTD	PMID:39298647
Sp2	Rat	4-hydroxynon-2-enal	decreases expression	ISO	SP2 (Homo sapiens)	6480464	4-hydroxy-2-nonenal results in decreased expression of SP2 mRNA	CTD	PMID:12419474
Sp2	Rat	4-hydroxyphenyl retinamide	decreases expression	ISO	Sp2 (Mus musculus)	6480464	Fenretinide results in decreased expression of SP2 mRNA	CTD	PMID:28973697
Sp2	Rat	6-propyl-2-thiouracil	decreases expression	EXP		6480464	Propylthiouracil results in decreased expression of SP2 mRNA	CTD	PMID:24780913 and PMID:30047161
Sp2	Rat	acrylamide	increases expression	EXP		6480464	Acrylamide results in increased expression of SP2 mRNA	CTD	PMID:28959563
Sp2	Rat	amitrole	decreases expression	EXP		6480464	Amitrole results in decreased expression of SP2 mRNA	CTD	PMID:30047161
Sp2	Rat	aristolochic acid A	decreases expression	ISO	SP2 (Homo sapiens)	6480464	aristolochic acid I results in decreased expression of SP2 mRNA	CTD	PMID:33212167
Sp2	Rat	Aroclor 1254	increases expression	ISO	SP2 (Homo sapiens)	6480464	Chlorodiphenyl (54% Chlorine) results in increased expression of SP2 mRNA	CTD	PMID:16934159
Sp2	Rat	benzo[a]pyrene	decreases methylation	ISO	SP2 (Homo sapiens)	6480464	Benzo(a)pyrene results in decreased methylation of SP2 promoter	CTD	PMID:27901495
Sp2	Rat	bisphenol A	affects expression	EXP		6480464	bisphenol A affects the expression of SP2 mRNA	CTD	PMID:25181051
Sp2	Rat	bisphenol A	increases expression	EXP		6480464	bisphenol A results in increased expression of SP2 mRNA	CTD	PMID:34947998
Sp2	Rat	bisphenol A	decreases expression	EXP		6480464	bisphenol A results in decreased expression of SP2 mRNA	CTD	PMID:30816183 and PMID:32528016
Sp2	Rat	buta-1,3-diene	decreases expression	ISO	Sp2 (Mus musculus)	6480464	1 and 3-butadiene results in decreased expression of SP2 mRNA	CTD	PMID:29038090
Sp2	Rat	butanal	decreases expression	ISO	SP2 (Homo sapiens)	6480464	butyraldehyde results in decreased expression of SP2 mRNA	CTD	PMID:26079696
Sp2	Rat	cadmium atom	multiple interactions	ISO	SP2 (Homo sapiens)	6480464	[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of SP2 mRNA	CTD	PMID:35301059
Sp2	Rat	cadmium dichloride	decreases expression	EXP		6480464	Cadmium Chloride results in decreased expression of SP2 mRNA	CTD	PMID:33453195
Sp2	Rat	cadmium dichloride	multiple interactions	ISO	SP2 (Homo sapiens)	6480464	[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of SP2 mRNA	CTD	PMID:35301059
Sp2	Rat	caffeine	decreases phosphorylation	ISO	SP2 (Homo sapiens)	6480464	Caffeine results in decreased phosphorylation of SP2 protein	CTD	PMID:35688186
Sp2	Rat	calciol	increases expression	ISO	Sp2 (Mus musculus)	6480464	Cholecalciferol results in increased expression of SP2 mRNA	CTD	PMID:17170073
Sp2	Rat	CGP 52608	multiple interactions	ISO	SP2 (Homo sapiens)	6480464	CGP 52608 promotes the reaction [RORA protein binds to SP2 gene]	CTD	PMID:28238834
Sp2	Rat	cisplatin	multiple interactions	ISO	SP2 (Homo sapiens)	6480464	[Cisplatin co-treated with jinfukang] results in decreased expression of SP2 mRNA	CTD	PMID:27392435
Sp2	Rat	cyclophosphamide	decreases expression	EXP		6480464	Cyclophosphamide results in decreased expression of SP2 mRNA	CTD	PMID:27281708
Sp2	Rat	dicrotophos	increases expression	ISO	SP2 (Homo sapiens)	6480464	dicrotophos results in increased expression of SP2 mRNA	CTD	PMID:28302478
Sp2	Rat	doxorubicin	decreases expression	ISO	SP2 (Homo sapiens)	6480464	Doxorubicin results in decreased expression of SP2 mRNA	CTD	PMID:29803840
Sp2	Rat	folic acid	decreases expression	ISO	Sp2 (Mus musculus)	6480464	Folic Acid results in decreased expression of SP2 mRNA	CTD	PMID:25629700
Sp2	Rat	folic acid	decreases expression	ISO	SP2 (Homo sapiens)	6480464	Folic Acid results in decreased expression of SP2 mRNA	CTD	PMID:21867686
Sp2	Rat	FR900359	affects phosphorylation	ISO	SP2 (Homo sapiens)	6480464	FR900359 affects the phosphorylation of SP2 protein	CTD	PMID:37730182
Sp2	Rat	furan	decreases expression	EXP		6480464	furan results in decreased expression of SP2 mRNA	CTD	PMID:25539665
Sp2	Rat	gentamycin	increases expression	EXP		6480464	Gentamicins results in increased expression of SP2 mRNA	CTD	PMID:33387578
Sp2	Rat	lead diacetate	increases expression	ISO	Sp2 (Mus musculus)	6480464	lead acetate results in increased expression of SP2 mRNA	CTD	PMID:20542052
Sp2	Rat	methimazole	decreases expression	EXP		6480464	Methimazole results in decreased expression of SP2 mRNA	CTD	PMID:30047161
Sp2	Rat	paracetamol	decreases expression	EXP		6480464	Acetaminophen results in decreased expression of SP2 mRNA	CTD	PMID:33387578
Sp2	Rat	phenobarbital	decreases expression	EXP		6480464	Phenobarbital results in decreased expression of SP2 mRNA	CTD	PMID:30047161
Sp2	Rat	silicon dioxide	increases expression	ISO	SP2 (Homo sapiens)	6480464	Silicon Dioxide results in increased expression of SP2 mRNA	CTD	PMID:25351596
Sp2	Rat	sodium arsenite	increases expression	ISO	SP2 (Homo sapiens)	6480464	sodium arsenite results in increased expression of SP2 mRNA	CTD	PMID:38568856
Sp2	Rat	Soman	increases expression	EXP		6480464	Soman results in increased expression of SP2 mRNA	CTD	PMID:19281266
Sp2	Rat	sulfadimethoxine	decreases expression	EXP		6480464	Sulfadimethoxine results in decreased expression of SP2 mRNA	CTD	PMID:30047161
Sp2	Rat	Tanshinone I	decreases expression	ISO	SP2 (Homo sapiens)	6480464	tanshinone results in decreased expression of SP2 mRNA	CTD	PMID:15849732
Sp2	Rat	tert-butyl hydroperoxide	decreases expression	ISO	SP2 (Homo sapiens)	6480464	tert-Butylhydroperoxide results in decreased expression of SP2 mRNA	CTD	PMID:12419474
Sp2	Rat	titanium dioxide	decreases methylation	ISO	Sp2 (Mus musculus)	6480464	titanium dioxide results in decreased methylation of SP2 promoter	CTD	PMID:35295148
Sp2	Rat	triphenyl phosphate	affects expression	ISO	SP2 (Homo sapiens)	6480464	triphenyl phosphate affects the expression of SP2 mRNA	CTD	PMID:37042841
Sp2	Rat	triptonide	decreases expression	ISO	Sp2 (Mus musculus)	6480464	triptonide results in decreased expression of SP2 mRNA	CTD	PMID:33045310
Sp2	Rat	tungsten	decreases expression	ISO	Sp2 (Mus musculus)	6480464	Tungsten results in decreased expression of SP2 mRNA	CTD	PMID:30912803
Sp2	Rat	urethane	increases expression	ISO	SP2 (Homo sapiens)	6480464	Urethane results in increased expression of SP2 mRNA	CTD	PMID:28818685
Sp2	Rat	valproic acid	decreases expression	ISO	SP2 (Homo sapiens)	6480464	Valproic Acid results in decreased expression of SP2 mRNA	CTD	PMID:22083351

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Sp2	Rat	circulatory system development	acts_upstream_of_or_within	ISO	Sp2 (Mus musculus)	1624291	MGI:4441277 PMID:20221402	RGD	PMID:20221402
Sp2	Rat	embryonic organ development	acts_upstream_of_or_within	ISO	Sp2 (Mus musculus)	1624291	MGI:4441280 PMID:20221402	RGD	PMID:20221402
Sp2	Rat	fibroblast proliferation	acts_upstream_of_or_within	ISO	Sp2 (Mus musculus)	1624291	MGI:4441280 PMID:20221402	RGD	PMID:20221402
Sp2	Rat	in utero embryonic development	acts_upstream_of_or_within	ISO	Sp2 (Mus musculus)	1624291	MGI:4441277 PMID:20221402	RGD	PMID:20221402
Sp2	Rat	multicellular organism growth	acts_upstream_of_or_within	ISO	Sp2 (Mus musculus)	1624291	MGI:4441277 more ...	RGD	PMID:20221402
Sp2	Rat	negative regulation of transcription by RNA polymerase II	involved_in	ISO	SP2 (Homo sapiens)	1624291	PMID:10744779	RGD	PMID:10744779
Sp2	Rat	regulation of transcription by RNA polymerase II	involved_in	IBA	CGD:CAL0000177853 more ...	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Sp2	Rat	nucleoplasm	located_in	ISO	SP2 (Homo sapiens) and UniProtKB:Q02086-1	1624291		RGD	GO_REF:0000052
Sp2	Rat	nucleus	located_in	IEA	UniProtKB-SubCell:SL-0191	1600115	GO_REF:0000044	UniProt	GO_REF:0000044

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Sp2	Rat	DNA-binding transcription factor activity, RNA polymerase II-specific	enables	IBA	FB:FBgn0000233 more ...	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Sp2	Rat	DNA-binding transcription repressor activity, RNA polymerase II-specific	enables	ISO	SP2 (Homo sapiens)	1624291	PMID:10744779	RGD	PMID:10744779
Sp2	Rat	histone deacetylase binding	enables	ISO	SP2 (Homo sapiens)	1624291	UniProtKB:Q92769 and PMID:17827154	RGD	PMID:17827154
Sp2	Rat	protein binding	enables	ISO	SP2 (Homo sapiens)	1624291	UniProtKB:P17252 more ...	RGD	PMID:21516116 more ...
Sp2	Rat	protein binding	enables	ISO	SP2 (Homo sapiens) and UniProtKB:Q02086-2	1624291	UniProtKB:P06396 more ...	RGD	PMID:32296183 and PMID:32814053
Sp2	Rat	RNA polymerase II cis-regulatory region sequence-specific DNA binding	enables	ISO	SP2 (Homo sapiens)	1624291	PMID:10744779	RGD	PMID:10744779
Sp2	Rat	RNA polymerase II cis-regulatory region sequence-specific DNA binding	enables	IBA	MGI:1277166 more ...	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Sp2	Rat	sequence-specific double-stranded DNA binding	enables	ISO	SP2 (Homo sapiens)	1624291	PMID:28473536	RGD	PMID:28473536
Sp2	Rat	zinc ion binding	enables	IEA	UniProtKB-KW:KW-0863	1600115	GO_REF:0000043	UniProt	GO_REF:0000043

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	GOA pipeline	RGD automated data pipeline
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

PMID:10744779	PMID:12477932	PMID:14576192	PMID:17827154	PMID:20221402	PMID:27889927

Sp2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	82,437,024 - 82,467,583 (-)	NCBI		GRCr8
mRatBN7.2	10	81,940,580 - 81,970,040 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	81,940,587 - 81,970,548 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	10	86,888,604 - 86,913,243 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	86,386,649 - 86,411,284 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	81,779,242 - 81,803,869 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	84,890,930 - 84,920,886 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	84,890,932 - 84,920,886 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	10	84,682,708 - 84,712,592 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	10	85,676,978 - 85,706,042 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	10	80,703,358 - 80,732,335 (-)	NCBI		Celera
Cytogenetic Map	10	q31	NCBI

SP2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	17	47,896,236 - 47,931,731 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	17	47,896,150 - 47,928,957 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	17	45,973,602 - 46,006,323 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	17	43,328,515 - 43,361,322 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	17	43,328,637 - 43,361,320	NCBI
Celera	17	42,426,326 - 42,459,131 (+)	NCBI		Celera
Cytogenetic Map	17	q21.32	NCBI
HuRef	17	41,342,083 - 41,374,897 (+)	NCBI		HuRef
CHM1_1	17	46,038,477 - 46,071,292 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	17	48,758,002 - 48,793,527 (+)	NCBI		T2T-CHM13v2.0

Sp2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	96,844,158 - 96,873,785 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	11	96,844,167 - 96,873,785 (-)	Ensembl		GRCm39 Ensembl
GRCm38	11	96,953,332 - 96,982,959 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	96,953,341 - 96,982,959 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	11	96,814,651 - 96,839,002 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	11	96,770,309 - 96,799,049 (-)	NCBI		MGSCv36	mm8
Celera	11	106,602,740 - 106,627,485 (-)	NCBI		Celera
Cytogenetic Map	11	D	NCBI
cM Map	11	60.17	NCBI

Sp2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955451	13,205,463 - 13,227,775 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955451	13,205,463 - 13,231,181 (-)	NCBI	ChiLan1.0	ChiLan1.0

SP2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	19	17,167,680 - 17,206,971 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	17	19,133,266 - 19,172,588 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	17	9,608,320 - 9,641,114 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	17	9,787,517 - 9,823,061 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	17	9,790,212 - 9,823,062 (-)	Ensembl	panpan1.1		panPan2

SP2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	9	24,229,883 - 24,244,911 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	9	24,215,549 - 24,243,795 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	9	23,687,526 - 23,712,710 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	9	25,014,570 - 25,039,748 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	9	25,015,031 - 25,039,745 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	9	23,784,663 - 23,809,841 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	9	24,045,471 - 24,070,672 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	9	24,172,235 - 24,197,444 (+)	NCBI		UU_Cfam_GSD_1.0

Sp2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	23,654,052 - 23,683,057 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936490	13,391,844 - 13,421,159 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936490	13,392,082 - 13,421,159 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SP2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	12	24,154,136 - 24,185,894 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	12	24,154,087 - 24,185,898 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	12	23,984,976 - 23,988,072 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SP2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	16	68,297,250 - 68,328,887 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	16	68,297,169 - 68,327,753 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666077	39,348,518 - 39,380,089 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Variants in Sp2
113 total Variants

Predicted Target Of

	Summary Value
Count of predictions:	149
Count of miRNA genes:	102
Interacting mature miRNAs:	110
Transcripts:	ENSRNOT00000068083
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1549846	Scl47	Serum cholesterol level QTL 47	3.6		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	10	50574707	95574707	Rat
1298069	Bp168	Blood pressure QTL 168	5.5		blood pressure trait (VT:0000183)	systolic blood pressure (CMO:0000004)	10	26521957	98003205	Rat
631552	Vetf2	Vascular elastic tissue fragility QTL 2	4.5	0.0002	aorta elastic tissue integrity trait (VT:0010556)	artery internal elastic lamina non-tumorous lesion count (CMO:0001913)	10	41142633	86142633	Rat
61449	Ciaa2	CIA Autoantibody QTL 2	7.1		blood autoantibody amount (VT:0003725)	calculated serum anti-type 2 collagen antibody titer (CMO:0001279)	10	63221094	107211142	Rat
631555	Bp134	Blood pressure QTL 134		0.001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	80515287	91230079	Rat
61325	Aia5	Adjuvant induced arthritis QTL 5		0.01	joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	23444813	104060283	Rat
1298078	Stresp5	Stress response QTL 5	2.99	0.00025	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	10	42045676	104670812	Rat
1549831	Bss6	Bone structure and strength QTL 6	4		lumbar vertebra strength trait (VT:0010574)	vertebra ultimate force (CMO:0001678)	10	57576521	102576521	Rat
70164	Bw21	Body weight QTL 21	4.36	0.00005	body mass (VT:0001259)	body weight (CMO:0000012)	10	53797494	98952626	Rat
61463	Bp12	Blood pressure QTL 12	6.3	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	41333258	86333258	Rat
2298548	Neuinf7	Neuroinflammation QTL 7	3.4		nervous system integrity trait (VT:0010566)	spinal cord RT1-B protein level (CMO:0002132)	10	72224939	107211142	Rat
1579919	Bp281	Blood pressure QTL 281		0.01	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	74372084	94965338	Rat
1302404	Cia27	Collagen induced arthritis QTL 27	2.6	0.0045	joint integrity trait (VT:0010548)	experimental arthritis severity measurement (CMO:0001459)	10	76452683	107211142	Rat
1300107	Rf18	Renal function QTL 18	3.41		urine output (VT:0003620)	timed urine volume (CMO:0000260)	10	78775516	98279596	Rat
8694173	Bw149	Body weight QTL 149	4.38	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	10	44441699	89441699	Rat
2300218	Hpcl2	Hepatic cholesterol level QTL 2			liver cholesterol amount (VT:0010498)	liver cholesterol level (CMO:0001597)	10	45029650	95600334	Rat
1554317	Bmd4	Bone mineral density QTL 4	9.4	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	10	19816042	99406971	Rat
70171	Cari1	Carrageenan-induced inflammation QTL 1	4.9	0.0005	hypodermis integrity trait (VT:0010550)	inflammatory exudate volume (CMO:0001429)	10	53797385	107211142	Rat
10450495	Bp383	Blood pressure QTL 383		0.002	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	76246085	94965338	Rat
61354	Pia10	Pristane induced arthritis QTL 10		0.01	joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	23444813	104060283	Rat
2292617	Ept18	Estrogen-induced pituitary tumorigenesis QTL 18	3.9		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	10	73453136	96120911	Rat
2301967	Cm73	Cardiac mass QTL 73	4.55		heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	10	14487011	89062041	Rat
2313103	Bss80	Bone structure and strength QTL 80	2	0.0001	tibia strength trait (VT:1000284)	tibia midshaft endosteal cross-sectional area (CMO:0001716)	10	62057807	107057807	Rat
2293646	Bss25	Bone structure and strength QTL 25	10.96	0.0001	femur morphology trait (VT:0000559)	femur cross-sectional area (CMO:0001661)	10	69738412	107211142	Rat
2303118	Mamtr7	Mammary tumor resistance QTL 7		0.003	mammary gland integrity trait (VT:0010552)	mammary tumor growth rate (CMO:0000344)	10	9658275	104670812	Rat
70188	BpQTLcluster1	Blood pressure QTL cluster 1	4.864		arterial blood pressure trait (VT:2000000)	pulse pressure (CMO:0000292)	1	42323132	87323132	Rat
2300172	Bmd57	Bone mineral density QTL 57	9.8	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	10	69738412	107211142	Rat
724516	Uae17	Urinary albumin excretion QTL 17	3.6		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	10	78210622	85220348	Rat
70193	Mcs7	Mammary carcinoma susceptibility QTL 7	2.38		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	10	72224939	107211142	Rat
2313105	Bss79	Bone structure and strength QTL 79	1.8	0.0001	tibia size trait (VT:0100001)	tibia midshaft cross-sectional area (CMO:0001717)	10	62057807	107057807	Rat
9589030	Epfw9	Epididymal fat weight QTL 9	19.24	0.001	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	10	44441699	89441699	Rat
1357344	Bp249	Blood pressure QTL 249		0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	66743655	98003205	Rat
2316949	Gluco60	Glucose level QTL 60	3.7		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	10	14487011	107057807	Rat
70198	BpQTLcluster9	Blood pressure QTL cluster 9	2.94		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	42323132	87323132	Rat
2306970	Anxrr22	Anxiety related response QTL 22	5.95		fear/anxiety-related behavior trait (VT:1000241)	number of periods of voluntary immobility (CMO:0001045)	10	61345276	98211570	Rat
1359017	Hrtrt21	Heart rate QTL 21	2.4		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	10	51772940	96772940	Rat
2293663	Bss33	Bone structure and strength QTL 33	9.34	0.0001	femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	10	69738412	107211142	Rat
7387312	Bw125	Body weight QTL 125	3	0.0047	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight (CMO:0000356)	10	64890616	107211142	Rat
2312672	Insul15	Insulin level QTL 15		0.01	blood insulin amount (VT:0001560)	serum insulin level (CMO:0000358)	10	57134272	102134272	Rat
6893357	Bw102	Body weight QTL 102	0.5	0.36	body mass (VT:0001259)	body weight (CMO:0000012)	10	80515287	101325465	Rat
2317029	Aia19	Adjuvant induced arthritis QTL 19	2.98		joint integrity trait (VT:0010548)	left rear ankle joint diameter (CMO:0002149)	10	66978955	107211142	Rat
2303589	Bw87	Body weight QTL 87	2		body mass (VT:0001259)	body weight (CMO:0000012)	10	81285008	107211142	Rat
724556	Pur2	Proteinuria QTL 2	5.5		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	10	22427500	90627625	Rat
2306793	Ean5	Experimental allergic neuritis QTL 5	4.7		nervous system integrity trait (VT:0010566)	IFNG-secreting splenocyte count (CMO:0002122)	10	72552416	93995749	Rat
61387	Bp1	Blood pressure QTL 1	5.1		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	10	51770177	107211142	Rat
2317039	Aia6	Adjuvant induced arthritis QTL 6	4.31		joint integrity trait (VT:0010548)	right rear ankle joint diameter (CMO:0002150)	10	66978955	107211142	Rat
2317043	Aia7	Adjuvant induced arthritis QTL 7	3.82		joint integrity trait (VT:0010548)	left rear ankle joint diameter (CMO:0002149)	10	37565079	82565079	Rat
2317042	Aia20	Adjuvant induced arthritis QTL 20	3.38		joint integrity trait (VT:0010548)	right rear ankle joint diameter (CMO:0002150)	10	37565079	82565079	Rat
2298481	Eau9	Experimental allergic uveoretinitis QTL 9		0.0169	uvea integrity trait (VT:0010551)	experimental autoimmune uveitis score (CMO:0001504)	10	65927233	82565079	Rat
61396	Bp9	Blood pressure QTL 9	4.8	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	68420376	107211142	Rat
1358915	Stresp7	Stress response QTL 7	3.52		blood norepinephrine amount (VT:0005663)	plasma norepinephrine level (CMO:0001010)	10	78899655	87307728	Rat
61402	Niddm3	Non-insulin dependent diabetes mellitus QTL 3	4.58		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	10	61345413	82564856	Rat
1331791	Cm31	Cardiac mass QTL 31	3.84606		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	10	29299504	107211142	Rat
70364	Bp72	Blood pressure QTL 72			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	51121100	96121100	Rat
10450498	Bp384	Blood pressure QTL 384		0.002	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	67750049	107211142	Rat
4889492	Pancm2	Pancreatic morphology QTL 2	3.2		pancreatic beta cell morphology trait (VT:0005217)	ratio of insulin-positive cell area to total area of splenic region of pancreas (CMO:0001814)	10	76748906	107211142	Rat
6893366	Bw106	Body weight QTL 106	0.3	0.47	body mass (VT:0001259)	body weight (CMO:0000012)	10	70199100	107211142	Rat
2293698	Bss43	Bone structure and strength QTL 43	5.33	0.0001	lumbar vertebra size trait (VT:0010518)	lumbar vertebra cross-sectional area (CMO:0001689)	10	59209888	104209888	Rat
631530	Tls3	T-lymphoma susceptibility QTL 3	0	0.0001	thymus integrity trait (VT:0010555)	percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)	10	51774612	95600334	Rat
1354608	Cm33	Cardiac mass QTL 33	2.8		heart left ventricle mass (VT:0007031)	heart left ventricle wet weight (CMO:0000071)	10	54809292	99809292	Rat
1558643	Cm44	Cardiac mass QTL 44	4.8	0.0000368	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	10	61345276	99703528	Rat
631535	Cm51	Cardiac mass QTL 51	3		heart mass (VT:0007028)	calculated heart weight (CMO:0000073)	10	51786282	91669536	Rat
631267	Cia20	Collagen induced arthritis QTL 20	3.2		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	23444813	104060283	Rat
1576308	Schws1	Schwannoma susceptibility QTL 1		0.0041	nervous system integrity trait (VT:0010566)	percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)	10	40035094	102359817	Rat
631269	Cia22	Collagen induced arthritis QTL 22	8.9		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	40035094	104060283	Rat
631268	Cia21	Collagen induced arthritis QTL 21	3.1		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	14487011	104060283	Rat
631270	Cia23	Collagen induced arthritis QTL 23	3.9		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	40035094	104060283	Rat
7411614	Foco18	Food consumption QTL 18		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	10	44441699	89441699	Rat
2325836	Bp346	Blood pressure QTL 346		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	76246085	84007272	Rat
6893336	Cm75	Cardiac mass QTL 75	0.1	0.87	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	10	61345276	99703528	Rat
12880053	Cm104	Cardiac mass QTL 104		0.009	heart right ventricle mass (VT:0007033)	heart right ventricle weight to body weight ratio (CMO:0000914)	10	73452992	83463334	Rat
631547	Bp87	Blood pressure QTL 87	4.5		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	47369470	92369470	Rat
61427	Cia16	Collagen induced arthritis QTL 16	3.2		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	6357896	96121100	Rat
2292438	Bp311	Blood pressure QTL 311			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	76246085	107211142	Rat
2312662	Slep8	Serum leptin concentration QTL 8		0.05	blood leptin amount (VT:0005667)	serum leptin level (CMO:0000780)	10	57134272	102134272	Rat
12880050	Am10	Aortic mass QTL 10		0.016	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	10	74372084	84007272	Rat
1358188	Ept9	Estrogen-induced pituitary tumorigenesis QTL 9	3.9		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	10	73453136	96120911	Rat
631537	Oia4	Oil induced arthritis QTL 4			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	75631887	87055282	Rat
634354	Rends3	Renal damage susceptibility QTL 3		0.05	kidney blood vessel morphology trait (VT:0000530)	organ lesion measurement (CMO:0000677)	10	79813789	85160854	Rat
1642980	Bp300	Blood pressure QTL 300			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	68383129	107211142	Rat
631542	Bp82	Blood pressure QTL 82	6.8		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	26521957	98952741	Rat
2312668	Scl65	Serum cholesterol level QTL 65		0.001	blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	10	57134272	102134272	Rat

RH144028

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	10	82,449,529 - 82,449,639 (+)	Marker Load Pipeline
mRatBN7.2	10	81,953,084 - 81,953,195 (+)	MAPPER	mRatBN7.2
Rnor_6.0	10	84,903,425 - 84,903,535	NCBI	Rnor6.0
Rnor_5.0	10	84,694,387 - 84,694,497	UniSTS	Rnor5.0
RGSC_v3.4	10	85,688,581 - 85,688,691	UniSTS	RGSC3.4
Celera	10	80,714,874 - 80,714,984	UniSTS
RH 3.4 Map	10	792.0	UniSTS
Cytogenetic Map	10	q31	UniSTS

RH131238

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	10	82,437,257 - 82,437,443 (+)	Marker Load Pipeline
mRatBN7.2	10	81,940,813 - 81,940,999 (+)	MAPPER	mRatBN7.2
Rnor_6.0	10	84,891,159 - 84,891,344	NCBI	Rnor6.0
Rnor_5.0	10	84,682,068 - 84,682,253	UniSTS	Rnor5.0
RGSC_v3.4	10	85,676,252 - 85,676,437	UniSTS	RGSC3.4
Celera	10	80,702,663 - 80,702,848	UniSTS
RH 3.4 Map	10	781.9	UniSTS
Cytogenetic Map	10	q31	UniSTS

AW533789

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	10	81,957,856 - 81,958,030 (+)	MAPPER	mRatBN7.2
Rnor_6.0	10	84,908,197 - 84,908,370	NCBI	Rnor6.0
Rnor_5.0	10	84,699,159 - 84,699,332	UniSTS	Rnor5.0
RGSC_v3.4	10	85,693,353 - 85,693,526	UniSTS	RGSC3.4
Celera	10	80,719,646 - 80,719,819	UniSTS
RH 3.4 Map	10	782.2	UniSTS
Cytogenetic Map	10	q31	UniSTS

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	60	31


RefSeq Transcripts	NM_001399622	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039086078	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039086079	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039086080	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063269117	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC168669	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473948	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000010	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000068083 ⟹ ENSRNOP00000059769

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	10	81,941,482 - 81,970,548 (-)	Ensembl
Rnor_6.0 Ensembl	10	84,891,821 - 84,920,886 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000087322 ⟹ ENSRNOP00000072347

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	10	81,940,587 - 81,965,132 (-)	Ensembl
Rnor_6.0 Ensembl	10	84,890,932 - 84,915,471 (-)	Ensembl

RefSeq Acc Id:

NM_001399622 ⟹ NP_001386551

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	82,437,029 - 82,461,597 (-)	NCBI
mRatBN7.2	10	81,940,585 - 81,965,154 (-)	NCBI

RefSeq Acc Id:

XM_039086078 ⟹ XP_038942006

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	82,437,024 - 82,465,798 (-)	NCBI
mRatBN7.2	10	81,940,580 - 81,970,040 (-)	NCBI

RefSeq Acc Id:

XM_039086079 ⟹ XP_038942007

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	82,437,024 - 82,452,512 (-)	NCBI
mRatBN7.2	10	81,940,580 - 81,956,068 (-)	NCBI

RefSeq Acc Id:

XM_039086080 ⟹ XP_038942008

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	82,437,024 - 82,453,458 (-)	NCBI
mRatBN7.2	10	81,940,580 - 81,957,014 (-)	NCBI

RefSeq Acc Id:

XM_063269117 ⟹ XP_063125187

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	82,437,024 - 82,467,583 (-)	NCBI


Protein RefSeqs	NP_001386551	(Get FASTA)	NCBI Sequence Viewer
	XP_038942006	(Get FASTA)	NCBI Sequence Viewer
	XP_038942007	(Get FASTA)	NCBI Sequence Viewer
	XP_038942008	(Get FASTA)	NCBI Sequence Viewer
	XP_063125187	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI68669	(Get FASTA)	NCBI Sequence Viewer
	EDM05834	(Get FASTA)	NCBI Sequence Viewer
	EDM05835	(Get FASTA)	NCBI Sequence Viewer
	EDM05836	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000059769
	ENSRNOP00000059769.2
	ENSRNOP00000072347
	ENSRNOP00000072347.1
	ENSRNOP00000110364

Ensembl Acc Id:

ENSRNOP00000072347 ⟸ ENSRNOT00000087322

Ensembl Acc Id:

ENSRNOP00000059769 ⟸ ENSRNOT00000068083

RefSeq Acc Id:	XP_038942006 ⟸ XM_039086078
- Peptide Label:	isoform X1
- UniProtKB:	D3ZSM5 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038942008 ⟸ XM_039086080
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038942007 ⟸ XM_039086079
- Peptide Label:	isoform X2

Protein Domains

C2H2-type

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-B5DEH3-F1-model_v2	AlphaFold	B5DEH3	1-612	view protein structure

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

RGD ID:

13697654

Promoter ID:

EPDNEW_R8162

Type:

single initiation site

Name:

Sp2_1

Description:

Sp2 transcription factor

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	10	84,915,493 - 84,915,553	EPDNEW

Database	Acc Id	Source(s)
BioCyc Gene	G2FUF-23444	BioCyc
Ensembl Genes	ENSRNOG00000010492	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000068083	ENTREZGENE
	ENSRNOT00000068083.2	UniProtKB/TrEMBL
	ENSRNOT00000087322	ENTREZGENE
	ENSRNOT00000087322.2	UniProtKB/TrEMBL
	ENSRNOT00000155912	ENTREZGENE
Gene3D-CATH	Classic Zinc Finger	UniProtKB/TrEMBL
InterPro	Znf_C2H2/integrase_DNA-bd	UniProtKB/TrEMBL
	Znf_C2H2_sf	UniProtKB/TrEMBL
NCBI Gene	303499	ENTREZGENE
PANTHER	KRUEPPEL-LIKE TRANSCRIPTION FACTOR	UniProtKB/TrEMBL
	PTHR23235:SF1	UniProtKB/TrEMBL
Pfam	zf-C2H2	UniProtKB/TrEMBL
PhenoGen	Sp2	PhenoGen
PROSITE	ZINC_FINGER_C2H2_1	UniProtKB/TrEMBL
	ZINC_FINGER_C2H2_2	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000010492	RatGTEx
SMART	ZnF_C2H2	UniProtKB/TrEMBL
Superfamily-SCOP	SSF57667	UniProtKB/TrEMBL
UniProt	A6HIH9_RAT	UniProtKB/TrEMBL
	B5DEH3	ENTREZGENE, UniProtKB/TrEMBL
	D3ZSM5	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2007-04-13		Sp2 transcription factor	Sp2	Sp2 transcription factor (mapped)	Name updated	737654	APPROVED
2007-04-12	Sp2	Sp2 transcription factor (mapped)	Sp2_mapped	Sp2 transcription factor (mapped)	Data merged from RGD:3739	737654	APPROVED
2006-11-20	Sp2	Sp2 transcription factor (mapped)			Symbol and Name status set to provisional	70820	PROVISIONAL
2005-11-17	Sp2_mapped	Sp2 transcription factor (mapped)	Sp2	Sp2 transcription factor	Symbol and Name updated	1556543	APPROVED
2003-04-09	Sp2	Sp2 transcription factor		Trans-acting transcription factor 2	Name updated	629478	APPROVED
2002-06-10	Sp2	Trans-acting transcription factor 2			Symbol and Name status set to approved	70586	APPROVED

Note Type	Note	Reference
gene_expression	expressed in nervous system during embryonic development	1300423
gene_process	may play a role in activation of P450scc transcription in nervous system	1300423

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable

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Imported Disease Annotations - ClinVar