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Gene: Ube2z (ubiquitin-conjugating enzyme E2Z) Rattus norvegicus
Symbol: Ube2z
Name: ubiquitin-conjugating enzyme E2Z
Description: Predicted to have cysteine-type endopeptidase inhibitor activity and ubiquitin conjugating enzyme activity. Predicted to be involved in negative regulation of apoptotic process; positive regulation of apoptotic process; and ubiquitin-dependent protein catabolic process. Predicted to localize to cytosol and nucleoplasm. Orthologous to human UBE2Z (ubiquitin conjugating enzyme E2 Z); PARTICIPATES IN ubiquitin/proteasome degradation pathway; INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,4-dinitrotoluene; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: E2 ubiquitin-conjugating enzyme Z; LOC303478; MGC124852; RGD1308347; similar to hypothetical protein FLJ13855; uba6-specific E2 conjugating enzyme 1; ubiquitin carrier protein Z; ubiquitin-conjugating enzyme E2 Z; ubiquitin-conjugating enzyme E2Z (putative); ubiquitin-protein ligase Z; use1
Homo sapiens (human) : UBE2Z (ubiquitin conjugating enzyme E2 Z)  HGNC  Alliance
Mus musculus (house mouse) : Ube2z (ubiquitin-conjugating enzyme E2Z)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ube2z (ubiquitin conjugating enzyme E2 Z)
Pan paniscus (bonobo/pygmy chimpanzee) : UBE2Z (ubiquitin conjugating enzyme E2 Z)
Canis lupus familiaris (dog) : UBE2Z (ubiquitin conjugating enzyme E2 Z)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ube2z (ubiquitin conjugating enzyme E2 Z)
Sus scrofa (pig) : UBE2Z (ubiquitin conjugating enzyme E2 Z)
Chlorocebus sabaeus (African green monkey) : UBE2Z (ubiquitin conjugating enzyme E2 Z)
Heterocephalus glaber (naked mole-rat) : Ube2z (ubiquitin conjugating enzyme E2 Z)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01083,869,703 - 83,888,823 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1083,869,704 - 83,888,823 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01083,674,572 - 83,693,693 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41084,762,405 - 84,781,526 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11084,778,519 - 84,796,326 (-)NCBI
Celera1079,765,580 - 79,784,755 (-)NCBICelera
Cytogenetic Map10q26NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Ube2z
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1308347
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.