Gene: Aoc3 (amine oxidase, copper containing 3) Rattus norvegicus
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Symbol: Aoc3
Name: amine oxidase, copper containing 3
Description: ENCODES a protein that exhibits primary amine oxidase activity; protein homodimerization activity; calcium ion binding (ortholog); INVOLVED IN aging; eating behavior; leukocyte migration involved in inflammatory response; PARTICIPATES IN beta-alanine metabolic pathway; carnosinemia pathway; GABA aminotransferase deficiency pathway; ASSOCIATED WITH aortic aneurysm; Choroidal Neovascularization; Diabetes Mellitus, Experimental ; FOUND IN extracellular space; intracellular membrane-bounded organelle; cell surface (ortholog); INTERACTS WITH 1,2-dimethylhydrazine; 2,2',4,4'-Tetrabromodiphenyl ether; 2,6-dinitrotoluene
AGR Description: Exhibits primary amine oxidase activity and protein homodimerization activity; involved in several processes, including aging, eating behavior, and leukocyte migration involved in inflammatory response; localizes to the extracellular space and intracellular membrane-bounded organelle; used to study aortic aneurysm, obesity, type 2 diabetes mellitus, and uveitis; biomarker of intracranial aneurysm; orthologous to human AOC3 (amine oxidase copper containing 3).
Merged Description: Exhibits primary amine oxidase activity and protein homodimerization activity; involved in several processes, including aging, eating behavior, and leukocyte migration involved in inflammatory response; localizes to the extracellular space and intracellular membrane-bounded organelle; used to study aortic aneurysm, obesity, type 2 diabetes mellitus, and uveitis; biomarker of intracranial aneurysm; orthologous to human AOC3 (amine oxidase copper containing 3); PARTICIPATES IN beta-alanine metabolic pathway; carnosinemia pathway; GABA aminotransferase deficiency pathway; INTERACTS WITH 1,2-dimethylhydrazine; 2,2',4,4'-Tetrabromodiphenyl ether; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: amine oxidase, copper containing 3 (vascular adhesion protein 1); copper amine oxidase; membrane primary amine oxidase; semicarbazide-sensitive amine oxidase; SSAO; VAP-1; vascular adhesion protein 1; VP97
Orthologs:
Homo sapiens (human) : AOC3 (amine oxidase copper containing 3)  HGNC  Alliance
Mus musculus (house mouse) : Aoc3 (amine oxidase, copper containing 3)  MGI  Alliance
Canis lupus familiaris (dog) : AOC3 (amine oxidase copper containing 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Aoc3 (amine oxidase copper containing 3)
Sus scrofa (pig) : LOC110256000 (membrane primary amine oxidase-like)
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Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01089,251,370 - 89,259,313 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01089,049,333 - 89,057,276 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41090,357,094 - 90,365,040 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11090,371,458 - 90,372,508 (+)NCBI
Celera1084,990,891 - 84,998,741 (+)NCBICelera
Cytogenetic Map10q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
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QTLs in Region (Rnor_6.0)

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Strain Sequence Variants (Rnor 5.0)
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Nomenclature History
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More on Aoc3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
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RGD Object Information
RGD ID: 62058
Created: 2001-04-11
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.