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Gene: Dhx58 (DEXH-box helicase 58) Rattus norvegicus
Symbol: Dhx58
Name: DEXH-box helicase 58
RGD ID: 1310093
Description: Predicted to have double-stranded RNA binding activity; single-stranded RNA binding activity; and zinc ion binding activity. Predicted to be involved in several processes, including negative regulation of innate immune response; regulation of cytokine production; and response to virus. Predicted to localize to cytoplasm. Orthologous to human DHX58 (DExH-box helicase 58); PARTICIPATES IN Retinoic acid-inducible gene (RIG) I-like receptor signaling pathway; INTERACTS WITH (+)-schisandrin B; 6-propyl-2-thiouracil; acetamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: DEXH (Asp-Glu-X-His) box polypeptide 58; Lgp2; LOC303538; probable ATP-dependent RNA helicase DHX58; RGD1310093; RNA helicase LGP2; similar to hypothetical protein FLJ11354
Homo sapiens (human) : DHX58 (DExH-box helicase 58)  HGNC  Alliance
Mus musculus (house mouse) : Dhx58 (DEXH (Asp-Glu-X-His) box polypeptide 58)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dhx58 (DExH-box helicase 58)
Pan paniscus (bonobo/pygmy chimpanzee) : DHX58 (DExH-box helicase 58)
Canis lupus familiaris (dog) : DHX58 (DExH-box helicase 58)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dhx58 (DExH-box helicase 58)
Sus scrofa (pig) : DHX58 (DExH-box helicase 58)
Chlorocebus sabaeus (African green monkey) : DHX58 (DExH-box helicase 58)
Heterocephalus glaber (naked mole-rat) : Dhx58 (DExH-box helicase 58)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01088,599,722 - 88,611,562 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1088,599,680 - 88,611,105 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01088,393,935 - 88,405,328 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41089,630,145 - 89,641,311 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11089,644,843 - 89,655,680 (-)NCBI
Celera1084,336,054 - 84,347,209 (-)NCBICelera
Cytogenetic Map10q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Dhx58
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1310093
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.