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Gene: Hdac5 (histone deacetylase 5) Rattus norvegicus
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Symbol: Hdac5
Name: histone deacetylase 5
Description: Exhibits chromatin binding activity and transcription factor binding activity. Predicted to contribute to transcription regulatory region DNA binding activity. Involved in several processes, including cellular response to lipopolysaccharide; response to activity; and response to cocaine. Localizes to the cytoplasm; nucleus; and protein-containing complex. Biomarker of acute kidney failure; attention deficit hyperactivity disorder; mental depression; middle cerebral artery infarction; and pulmonary hypertension. Orthologous to human HDAC5 (histone deacetylase 5); PARTICIPATES IN calcium/calmodulin dependent kinase 2 signaling pathway; histone modification pathway; INTERACTS WITH (+)-schisandrin B; 4-aminopyridine; acrylamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Orthologs:
Homo sapiens (human) : HDAC5 (histone deacetylase 5)  HGNC  Alliance
Mus musculus (house mouse) : Hdac5 (histone deacetylase 5)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hdac5 (histone deacetylase 5)
Pan paniscus (bonobo/pygmy chimpanzee) : HDAC5 (histone deacetylase 5)
Canis lupus familiaris (dog) : HDAC5 (histone deacetylase 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hdac5 (histone deacetylase 5)
Sus scrofa (pig) : HDAC5 (histone deacetylase 5)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01090,140,183 - 90,169,853 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01089,927,486 - 89,956,390 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41091,266,512 - 91,277,705 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11091,290,701 - 91,292,062 (-)NCBI
Celera1085,868,901 - 85,904,236 (-)NCBICelera
Cytogenetic Map10q32.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Hdac5
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 619980
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.