Gene: Wnk4 (WNK lysine deficient protein kinase 4) Rattus norvegicus
Symbol: Wnk4
Name: WNK lysine deficient protein kinase 4
Description: ENCODES a protein that exhibits protein serine/threonine kinase activity; ATP binding (ortholog); chloride channel inhibitor activity (ortholog); INVOLVED IN negative regulation of sodium ion transport; protein phosphorylation; chloride transport (ortholog); ASSOCIATED WITH pseudohypoaldosteronism (ortholog); pseudohypoaldosteronism, type IIB (ortholog); Smith-Magenis syndrome (ortholog); FOUND IN cytosol; membrane; bicellular tight junction (ortholog); INTERACTS WITH 1,3-dinitrobenzene; 3,3',4,4',5-pentachlorobiphenyl; ammonium chloride
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Ac2-059; Prkwnk4; protein kinase lysine-deficient 4; protein kinase with no lysine 4; protein kinase, lysine deficient 4; protein kinase, lysine-deficient 4; serine/threonine-protein kinase WNK4; WNK4 Ser/Thr kinase
Homo sapiens (human) : WNK4 (WNK lysine deficient protein kinase 4)  HGNC  Alliance
Mus musculus (house mouse) : Wnk4 (WNK lysine deficient protein kinase 4)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Wnk4 (WNK lysine deficient protein kinase 4)
Pan paniscus (bonobo/pygmy chimpanzee) : WNK4 (WNK lysine deficient protein kinase 4)
Canis lupus familiaris (dog) : VPS25 (vacuolar protein sorting 25 homolog)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Wnk4 (WNK lysine deficient protein kinase 4)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01089,181,139 - 89,198,213 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01088,979,661 - 88,997,344 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41090,289,273 - 90,306,225 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11090,303,667 - 90,320,558 (+)NCBI
Celera1084,920,709 - 84,937,662 (+)NCBICelera
Cytogenetic Map10q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Wnk4
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 631401
Created: 2003-08-13
Species: Rattus norvegicus
Last Modified: 2018-04-10
Status: ACTIVE