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Gene: Itga3 (integrin subunit alpha 3) Rattus norvegicus
Symbol: Itga3
Name: integrin subunit alpha 3
RGD ID: 1310333
Description: Exhibits several functions, including fibronectin binding activity; integrin binding activity; and laminin binding activity. Involved in several processes, including maternal process involved in female pregnancy; positive regulation of epithelial cell migration; and regulation of cell projection organization. Localizes to several cellular components, including growth cone filopodium; integrin alpha3-beta1 complex; and perinuclear region of cytoplasm. Biomarker of glomerulonephritis and myocardial infarction. Orthologous to human ITGA3 (integrin subunit alpha 3); PARTICIPATES IN altered Reelin signaling pathway; integrin mediated signaling pathway; interleukin-23 signaling pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine; all-trans-retinoic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: integrin alpha 3 ; integrin alpha-3; integrin, alpha 3; LOC360606
Homo sapiens (human) : ITGA3 (integrin subunit alpha 3)  HGNC  Alliance
Mus musculus (house mouse) : Itga3 (integrin alpha 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Itga3 (integrin subunit alpha 3)
Pan paniscus (bonobo/pygmy chimpanzee) : ITGA3 (integrin subunit alpha 3)
Canis lupus familiaris (dog) : ITGA3 (integrin subunit alpha 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Itga3 (integrin subunit alpha 3)
Sus scrofa (pig) : ITGA3 (integrin subunit alpha 3)
Chlorocebus sabaeus (African green monkey) : ITGA3 (integrin subunit alpha 3)
Heterocephalus glaber (naked mole-rat) : Itga3 (integrin subunit alpha 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01082,855,841 - 82,887,755 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1082,855,613 - 82,887,497 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01082,666,856 - 82,698,319 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41083,728,710 - 83,759,576 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11083,744,399 - 83,774,825 (-)NCBI
Celera1078,763,866 - 78,796,174 (-)NCBICelera
Cytogenetic Map10q26NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Itga3
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1310333
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-09-15
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.