Tmsb10l2 (thymosin, beta 10 like 2) - Rat Genome Database

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Gene: Tmsb10l2 (thymosin, beta 10 like 2) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Tmsb10l2 (Ensembl: Tmsb10-ps6)
Name: thymosin, beta 10 like 2 (Ensembl:thymosin, beta 10, pseudogene 6)
RGD ID: 9417566
Description: Predicted to enable actin monomer binding activity. Predicted to be involved in regulation of cell migration. Predicted to be located in cytoskeleton. Predicted to be active in cytoplasm.
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC103693420; thymosin beta-10 pseudogene; thymosin beta-10-like
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81079,208,594 - 79,209,080 (+)NCBIGRCr8
mRatBN7.21078,711,666 - 78,711,911 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1078,711,745 - 78,711,879 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01081,450,792 - 81,451,039 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Celera1077,509,559 - 77,509,806 (+)NCBICelera
Cytogenetic Map10q26NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Tmsb10l2Ratactin filament organization involved_inIEAUniRule:UR0009547541600115GO_REF:0000104UniProtGO_REF:0000104
Tmsb10l2Ratactin filament organization involved_inIEAInterPro:IPR0011521600115GO_REF:0000002InterProGO_REF:0000002
Tmsb10l2Ratregulation of cell migration involved_inIBAMGI:99510 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Tmsb10l2Ratcytoplasm is_active_inIBAMGI:99510 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Tmsb10l2Ratcytoplasm located_inIEAUniProtKB-KW:KW-09631600115GO_REF:0000043UniProtGO_REF:0000043
Tmsb10l2Ratcytoskeleton located_inIEAUniRule:UR0009547541600115GO_REF:0000104UniProtGO_REF:0000104
Tmsb10l2Ratcytoskeleton located_inIEAUniProtKB-KW:KW-02061600115GO_REF:0000043UniProtGO_REF:0000043
Tmsb10l2Ratcytoskeleton located_inIEAUniProtKB-SubCell:SL-00901600115GO_REF:0000044UniProtGO_REF:0000044

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Tmsb10l2Ratactin binding enablesIEAUniProtKB-KW:KW-00091600115GO_REF:0000043UniProtGO_REF:0000043
Tmsb10l2Ratactin monomer binding enablesIEAInterPro:IPR0011521600115GO_REF:0000002InterProGO_REF:0000002
Tmsb10l2Ratactin monomer binding enablesIEAUniRule:UR0009547541600115GO_REF:0000104UniProtGO_REF:0000104
Tmsb10l2Ratactin monomer binding enablesIBAMGI:3843061 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033



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Variants in Tmsb10l2
1 total Variants

1 to 10 of 85 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1549846Scl47Serum cholesterol level QTL 473.6blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)105057470795574707Rat
1298069Bp168Blood pressure QTL 1685.5blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)102652195798003205Rat
2293669Bmd33Bone mineral density QTL 334.50.0001femur strength trait (VT:0010010)femoral neck polar moment of inertia (CMO:0001670)104944455181709989Rat
631552Vetf2Vascular elastic tissue fragility QTL 24.50.0002aorta elastic tissue integrity trait (VT:0010556)artery internal elastic lamina non-tumorous lesion count (CMO:0001913)104114263386142633Rat
61449Ciaa2CIA Autoantibody QTL 27.1blood autoantibody amount (VT:0003725)calculated serum anti-type 2 collagen antibody titer (CMO:0001279)1063221094107211142Rat
61325Aia5Adjuvant induced arthritis QTL 50.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023444813104060283Rat
1298078Stresp5Stress response QTL 52.990.00025blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)1042045676104670812Rat
2293679Bmd30Bone mineral density QTL 303.50.0001femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)104944455181709989Rat
1549831Bss6Bone structure and strength QTL 64lumbar vertebra strength trait (VT:0010574)vertebra ultimate force (CMO:0001678)1057576521102576521Rat
70164Bw21Body weight QTL 214.360.00005body mass (VT:0001259)body weight (CMO:0000012)105379749498952626Rat

1 to 10 of 85 rows





RefSeq Transcripts XM_039087713 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAXUCZ010000010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000055447   ⟹   ENSRNOP00000052313
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1078,711,745 - 78,711,879 (+)Ensembl
RefSeq Acc Id: XM_039087713   ⟹   XP_038943641
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81079,208,594 - 79,209,080 (+)NCBI
mRatBN7.21078,711,666 - 78,711,911 (+)NCBI
Protein RefSeqs XP_038943641 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000052313
  ENSRNOP00000052313.3
RefSeq Acc Id: XP_038943641   ⟸   XM_039087713
- UniProtKB: A0A8L2QPJ1 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000052313   ⟸   ENSRNOT00000055447


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 17 of 17 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-23643 BioCyc
Ensembl Genes ENSRNOG00000036921 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000055447 ENTREZGENE
  ENSRNOT00000055447.3 UniProtKB/TrEMBL
Gene3D-CATH 1.20.5.520 UniProtKB/TrEMBL
InterPro Beta-thymosin UniProtKB/TrEMBL
  Beta-thymosin_sf UniProtKB/TrEMBL
NCBI Gene LOC103693420 ENTREZGENE
PANTHER PTHR12021 UniProtKB/TrEMBL
  THYMOSIN BETA-10 UniProtKB/TrEMBL
Pfam Thymosin UniProtKB/TrEMBL
PhenoGen Tmsb10l2 PhenoGen
PIRSF Thymosin_beta UniProtKB/TrEMBL
PROSITE THYMOSIN_B4 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000036921 RatGTEx
SMART THY UniProtKB/TrEMBL
UniProt A0A8L2QPJ1 ENTREZGENE, UniProtKB/TrEMBL
1 to 17 of 17 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-09-19 Tmsb10l2  thymosin, beta 10 like 2  LOC103693420  thymosin beta-10 pseudogene  Symbol and Name Changed 1299863 APPROVED
2014-08-25 LOC103693420  thymosin beta-10 pseudogene      Symbol and Name status set to provisional 70820 PROVISIONAL