Gene: Gast (gastrin) Rattus norvegicus
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Symbol: Gast
Name: gastrin
Description: ENCODES a protein that exhibits hormone activity; INVOLVED IN G protein-coupled receptor signaling pathway; signal transduction; PARTICIPATES IN cimetidine pharmacodynamics pathway; esomeprazole pharmacodynamics pathway; famotidine pharmacodynamics pathway; ASSOCIATED WITH adenocarcinoma (ortholog); Barrett's esophagus (ortholog); Colonic Neoplasms (ortholog); INTERACTS WITH 3-isobutyl-1-methyl-7H-xanthine; 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole; 6-propyl-2-thiouracil
AGR Description: Exhibits hormone activity; involved in G protein-coupled receptor signaling pathway; predicted to localize to the extracellular space; orthologous to human GAST (gastrin).
Merged Description: Exhibits hormone activity; involved in G protein-coupled receptor signaling pathway; predicted to localize to the extracellular space; orthologous to human GAST (gastrin); PARTICIPATES IN cimetidine pharmacodynamics pathway; esomeprazole pharmacodynamics pathway; famotidine pharmacodynamics pathway; INTERACTS WITH 3-isobutyl-1-methyl-7H-xanthine; 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Gas; PPG34
Orthologs:
Homo sapiens (human) : GAST (gastrin)  HGNC  Alliance
Mus musculus (house mouse) : Gast (gastrin)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gast (gastrin)
Pan paniscus (bonobo/pygmy chimpanzee) : GAST (gastrin)
Canis lupus familiaris (dog) : GAST (gastrin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gast (gastrin)
Sus scrofa (pig) : GAST (gastrin)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01088,245,532 - 88,248,485 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01088,038,779 - 88,041,731 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41089,273,628 - 89,276,192 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11089,287,997 - 89,290,562 (+)NCBI
Celera1083,982,177 - 83,985,941 (+)NCBICelera
Cytogenetic Map10q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Gast
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2662
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.