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Gene: Srsf1 (serine and arginine rich splicing factor 1) Rattus norvegicus
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Symbol: Srsf1
Name: serine and arginine rich splicing factor 1
Description: Exhibits protein kinase B binding activity. Involved in several processes, including alternative mRNA splicing, via spliceosome; liver regeneration; and positive regulation of RNA splicing. Localizes to the cytoplasm and nucleus. Predicted to colocalize with the exon-exon junction complex. Biomarker of hepatocellular carcinoma. Orthologous to human SRSF1 (serine and arginine rich splicing factor 1); PARTICIPATES IN spliceosome pathway; INTERACTS WITH 6-propyl-2-thiouracil; all-trans-retinoic acid; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: LOC689890; serine/arginine-rich splicing factor 1; Sfrs1; similar to splicing factor, arginine/serine-rich 1 (ASF/SF2); splicing factor, arginine/serine-rich 1; splicing factor, arginine/serine-rich 1B
Orthologs:
Homo sapiens (human) : SRSF1 (serine and arginine rich splicing factor 1)  HGNC  Alliance
Mus musculus (house mouse) : Srsf1 (serine and arginine-rich splicing factor 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Srsf1 (serine and arginine rich splicing factor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SRSF1 (serine and arginine rich splicing factor 1)
Canis lupus familiaris (dog) : SRSF1 (serine and arginine rich splicing factor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Srsf1 (serine and arginine rich splicing factor 1)
Sus scrofa (pig) : SRSF1 (serine and arginine rich splicing factor 1)
Chlorocebus sabaeus (green monkey) : SRSF1 (serine and arginine rich splicing factor 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01075,334,200 - 75,341,197 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1075,335,146 - 75,341,197 (+)Ensembl
Rnor_5.01074,759,412 - 74,765,821 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41076,339,824 - 76,344,552 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1071,749,406 - 71,755,457 (+)NCBICelera
Cytogenetic Map10q26NCBI
JBrowse: View Region in Genome Browser (JBrowse)
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Genomics

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RNA-SEQ Expression

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Strain Sequence Variants (Rnor 6.0)

Additional Information

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Nomenclature History
  
More on Srsf1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1587490
Created: 2006-11-19
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE



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