Col1a1 (collagen type I alpha 1 chain) - Rat Genome Database
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Gene: Col1a1 (collagen type I alpha 1 chain) Rattus norvegicus
Symbol: Col1a1
Name: collagen type I alpha 1 chain
RGD ID: 61817
Description: Predicted to have several functions, including identical protein binding activity; platelet-derived growth factor binding activity; and protease binding activity. Involved in several processes, including cellular response to growth factor stimulus; cellular response to mechanical stimulus; and cellular response to retinoic acid. Localizes to several cellular components, including Golgi apparatus; endoplasmic reticulum; and secretory granule. Used to study cholestasis and non-alcoholic fatty liver disease. Biomarker of several diseases, including artery disease (multiple); bladder neck obstruction; liver disease (multiple); pulmonary fibrosis; and ureteral obstruction. Human ortholog(s) of this gene implicated in several diseases, including Ehlers-Danlos syndrome arthrochalasia type 1; bone disease (multiple); cutaneous leishmaniasis; dermatofibrosarcoma protuberans; and tooth disease (multiple). Orthologous to human COL1A1 (collagen type I alpha 1 chain); PARTICIPATES IN acenocoumarol pharmacodynamics pathway; alteplase pharmacodynamics pathway; aminocaproic acid pharmacodynamics pathway; INTERACTS WITH (+)-schisandrin B; (R)-carnitine; (R)-lipoic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: alpha-1 type I collagen; COLIA1; collagen alpha-1(I) chain; collagen, type 1, alpha 1; collagen, type I, alpha 1; procollagen type I alpha 1; procollagen type I, alpha 1; procollagen, type 1, alpha 1; procollagen, type I, alpha 1 ; type I-alpha 1 collagen
RGD Orthologs
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01082,745,801 - 82,762,790 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1082,745,801 - 82,762,789 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01082,563,434 - 82,580,364 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41083,622,438 - 83,639,368 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11083,636,918 - 83,653,733 (+)NCBI
Celera1078,658,450 - 78,675,438 (+)NCBICelera
Cytogenetic Map10q26NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations     Click to see Annotation Detail View
aggressive periodontitis  (ISO)
alcoholic hepatitis  (ISO)
aortic valve insufficiency  (ISO)
Arteriovenous Fistula  (IEP)
autoimmune disease  (ISO)
beta thalassemia  (ISO)
Bisphosphonate-Associated Osteonecrosis of the Jaw  (ISO)
bladder neck obstruction  (IEP)
Bone Fractures  (ISO)
Caffey disease  (ISO)
calcinosis  (ISO)
Cardiac Fibrosis  (IDA,IEP)
cholangitis  (ISO)
cholestasis  (IDA,IEP,ISO)
chronic obstructive pulmonary disease  (ISO)
Chronic Pancreatitis  (IDA)
Combined Osteogenesis Imperfecta and Ehlers-Danlos Syndrome 1  (ISO)
connective tissue disease  (ISO)
Contracture  (IEP)
cutaneous leishmaniasis  (ISO)
degenerative disc disease  (ISO)
dentinogenesis imperfecta  (ISO)
dermatofibrosarcoma protuberans  (ISO)
Diabetic Nephropathies  (IEP)
Dissecting Aneurysm  (ISO)
Ehlers-Danlos syndrome  (ISO,ISS)
Ehlers-Danlos syndrome arthrochalasia type 1  (ISO)
Ehlers-Danlos syndrome arthrochalasia type 2  (ISO)
Ehlers-Danlos syndrome cardiac valvular type  (ISO)
Ehlers-Danlos syndrome classic type 1  (ISO)
Ehlers-Danlos syndrome classic type 2  (ISO)
Ehlers-Danlos Syndrome Type 7  (ISO)
end stage renal disease  (ISO)
Experimental Liver Cirrhosis  (IDA,IEP,IMP,ISO)
extrahepatic cholestasis  (ISO)
Femoral Fractures  (IDA)
Fibrosis  (ISO)
Fractures, Multiple  (ISO)
genetic disease  (ISO)
heart valve disease  (ISO)
hemorrhagic disease  (ISO)
Hernia, Ventral  (IDA)
High Myopia  (ISO)
Human Viral Hepatitis  (ISO)
Hypertelorism  (ISO)
hypertension  (ISO)
Hypertensive Nephropathy  (IEP)
Intervertebral Disc Disease  (ISO)
Joint Instability  (ISO)
Keloid  (ISO)
Left Ventricular Hypertrophy  (ISO)
Lipodermatosclerosis  (ISO)
liver benign neoplasm  (IEP)
liver cirrhosis  (ISO)
lupus nephritis  (ISO)
Metabolic Bone Diseases  (ISO)
multiple sclerosis  (ISO)
myocardial infarction  (IEP)
myocarditis  (ISO)
myopia  (ISO)
Nephrogenic Fibrosing Dermopathy  (ISO)
nephrosclerosis  (ISO)
nephrotic syndrome  (ISO)
non-alcoholic fatty liver disease  (IDA,ISO)
ocular hypertension  (ISO)
open-angle glaucoma  (ISO)
oral submucous fibrosis  (ISO)
osteoarthritis  (ISO)
Osteoarthritis, Experimental  (IEP)
Osteoarthritis, Hip  (ISO)
osteogenesis imperfecta  (ISO)
osteogenesis imperfecta type 1  (ISO)
osteogenesis imperfecta type 2  (ISO)
osteogenesis imperfecta type 2C  (ISO)
osteogenesis imperfecta type 3  (ISO)
osteogenesis imperfecta type 4  (ISO)
osteoporosis  (ISO)
otosclerosis  (ISO)
Postmenopausal Osteoporosis  (ISO)
primary biliary cholangitis  (IEP)
prostate cancer  (ISO)
pulmonary fibrosis  (IEP,ISO)
pulmonary hypertension  (IEP)
Spontaneous Abortions  (ISO)
systemic scleroderma  (ISO)
Tendon Injuries  (IDA)
thoracic aortic aneurysm  (ISO)
Trachomatous Trichiasis  (ISO)
ulcerative colitis  (ISO)
ureteral obstruction  (IEP)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP,ISO)
(+)-Tetrandrine  (ISO)
(-)-epigallocatechin 3-gallate  (ISO)
(2R,4R)-1-[(2S)-5-(diaminomethylideneamino)-2-[(3-methyl-1,2,3,4-tetrahydroquinolin-8-yl)sulfonylamino]-1-oxopentyl]-4-methyl-2-piperidinecarboxylic acid  (ISO)
(R)-carnitine  (EXP)
(R)-lipoic acid  (EXP)
(R)-mevalonic acid  (ISO)
(R)-noradrenaline  (EXP)
(S)-nicotine  (ISO)
1,2-dimethylhydrazine  (ISO)
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine  (ISO)
1-naphthyl isothiocyanate  (EXP,ISO)
1-stearoyl-2-arachidonoyl-sn-glycerol  (ISO)
15-deoxy-Delta(12,14)-prostaglandin J2  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
2,4,6-trinitrobenzenesulfonic acid  (ISO)
2-(3,4-dimethoxyphenyl)-5-\{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino\}-2-(propan-2-yl)pentanenitrile  (ISO)
2-amino-2-deoxy-D-galactopyranose  (EXP)
2-amino-2-deoxy-D-glucopyranose  (ISO)
2-butoxyethanol  (ISO)
2-hydroxyethyl methacrylate  (ISO)
2-trans,6-trans,10-trans-geranylgeranyl diphosphate  (ISO)
24,25-Dihydroxyvitamin D  (ISO)
3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine  (EXP)
3,3',4,4',5-pentachlorobiphenyl  (EXP,ISO)
3,3',5-triiodo-L-thyronine  (EXP)
3,4-methylenedioxymethamphetamine  (ISO)
3,7-dihydropurine-6-thione  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (EXP,ISO)
3H-1,2-dithiole-3-thione  (EXP)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxynon-2-enal  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5'-S-methyl-5'-thioadenosine  (ISO)
5-(1,4-diazepane-1-sulfonyl)isoquinoline  (ISO)
5-aza-2'-deoxycytidine  (EXP,ISO)
5-azacytidine  (ISO)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (EXP)
6alpha-methylprednisolone  (EXP,ISO)
8'-apo-beta,psi-caroten-8'-al  (ISO)
9-cis-retinoic acid  (ISO)
acetaldehyde  (EXP,ISO)
acetic acid  (ISO)
acrolein  (ISO)
acrylamide  (EXP)
actinomycin D  (ISO)
adenine  (EXP)
AICA ribonucleotide  (ISO)
aldehydo-D-glucosamine  (ISO)
aldehydo-D-glucose  (EXP,ISO)
aldosterone  (EXP)
all-trans-4-oxoretinoic acid  (ISO)
all-trans-4-oxoretinol  (ISO)
all-trans-retinoic acid  (EXP,ISO)
all-trans-retinol  (ISO)
allyl isothiocyanate  (ISO)
alpha-pinene  (ISO)
aluminium oxide  (ISO)
AM-251  (ISO)
ambroxol  (EXP)
aminoguanidine  (EXP)
amlodipine  (EXP)
amosite asbestos  (EXP)
amphetamine  (EXP)
amphibole asbestos  (ISO)
andrographolide  (EXP,ISO)
anthocyanin  (EXP)
arsenous acid  (ISO)
atorvastatin calcium  (ISO)
atrazine  (ISO)
azathioprine  (ISO)
azelastine  (ISO)
baicalein  (ISO)
benzene  (EXP)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[b]fluoranthene  (ISO)
Benzo[ghi]perylene  (ISO)
berberine  (ISO)
beta-carotene  (ISO)
beta-D-glucosamine  (ISO)
beta-naphthoflavone  (EXP,ISO)
bezafibrate  (EXP,ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
bleomycin A2  (EXP,ISO)
boron atom  (ISO)
boron nitride  (ISO)
BQ 123  (ISO)
bromochloroacetic acid  (ISO)
bucladesine  (ISO)
butanal  (ISO)
cadmium atom  (EXP,ISO)
cadmium dichloride  (EXP,ISO)
caffeine  (EXP,ISO)
calcitriol  (EXP,ISO)
calcium dichloride  (ISO)
calcium dihydroxide  (ISO)
camostat  (EXP)
capsaicin  (EXP)
carbamazepine  (ISO)
carbon nanotube  (ISO)
carmustine  (ISO)
carvedilol  (EXP)
casticin  (ISO)
celecoxib  (EXP)
ceruletide  (EXP,ISO)
chenodeoxycholic acid  (EXP,ISO)
chloramphenicol  (ISO)
chlorogenic acid  (EXP,ISO)
cholate  (EXP)
choline  (EXP,ISO)
chromium(6+)  (ISO)
chrysene  (ISO)
ciglitazone  (ISO)
cisplatin  (ISO)
clodronic acid  (ISO)
clofibrate  (ISO)
clofibric acid  (EXP)
Clofop  (EXP)
clothianidin  (ISO)
cocaine  (EXP)
coenzyme Q10  (EXP)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
cortisol  (EXP)
crocidolite asbestos  (ISO)
cucurbitacin B  (ISO)
cucurbitacin E  (EXP)
curcumin  (EXP,ISO)
cycloheximide  (ISO)
cyclosporin A  (ISO)
cystamine  (EXP)
cytarabine  (ISO)
cytochalasin D  (ISO)
D-glucose  (EXP,ISO)
desferrioxamine B  (EXP)
dexamethasone  (EXP,ISO)
dextran sulfate  (ISO)
diarsenic trioxide  (ISO)
diazepam  (ISO)
diethyl maleate  (EXP)
diethylstilbestrol  (ISO)
diiodine  (ISO)
diltiazem  (ISO)
dimethyl sulfoxide  (EXP)
dimethylarsinous acid  (ISO)
diminazene diaceturate  (ISO)
dioxygen  (EXP,ISO)
dipyridamole  (EXP,ISO)
disodium selenite  (ISO)
diuron  (EXP)
divanadium pentaoxide  (ISO)
dorsomorphin  (ISO)
doxazosin  (EXP)
doxorubicin  (EXP,ISO)
EC (peptidyl-dipeptidase A) inhibitor  (EXP)
elemental boron  (ISO)
elemental selenium  (ISO)
emodin  (EXP)
enalapril  (ISO)
endosulfan  (ISO)
entinostat  (ISO)
enzacamene  (EXP)
epalrestat  (ISO)
eplerenone  (EXP)
eprosartan  (EXP)
ethanol  (EXP,ISO)
ethyl methanesulfonate  (ISO)
ethylisopropylamiloride  (EXP)
excitatory amino acid agonist  (ISO)
fasudil hydrochloride  (ISO)
fenofibrate  (ISO)
fenvalerate  (ISO)
ferric ammonium citrate  (ISO)
fingolimod hydrochloride  (ISO)
folic acid  (ISO)
folpet  (ISO)
fomepizole  (EXP)
fonofos  (ISO)
fulvestrant  (EXP)
fumonisin B1  (ISO)
furan  (EXP)
genistein  (EXP,ISO)
geraniol  (EXP)
glucagon  (ISO)
glucose  (EXP,ISO)
glycerol 2-phosphate  (ISO)
glycyrrhetinate  (ISO)
glycyrrhetinic acid  (ISO)
glyoxal  (ISO)
gold atom  (ISO)
gold(0)  (ISO)
griseofulvin  (ISO)
guaiazulene  (ISO)
GW 4064  (EXP)
heptachlor  (ISO)
hesperetin  (EXP)
Hexachloro-1,3-butadiene  (EXP)
hexadecanoic acid  (ISO)
Honokiol  (EXP)
hydralazine  (ISO)
hydrogen peroxide  (EXP,ISO)
hydroquinone  (ISO)
indole-3-methanol  (EXP)
indometacin  (ISO)
iron atom  (EXP)
iron dextran  (ISO)
iron(0)  (EXP)
iron(III) nitrilotriacetate  (EXP)
isoflavones  (ISO)
isoprenaline  (EXP,ISO)
isorhamnetin  (ISO)
isotretinoin  (EXP)
kainic acid  (ISO)
L-ascorbic acid  (ISO)
L-cysteine  (EXP)
L-methionine  (EXP,ISO)
lead diacetate  (EXP)
lead(0)  (ISO)
lead(2+)  (ISO)
leukotriene B4  (ISO)
levonorgestrel  (ISO)
linoleic acid  (ISO)
lipoic acid  (EXP)
lipopolysaccharide  (EXP,ISO)
lithocholic acid  (ISO)
losartan  (EXP,ISO)
LY 364947  (ISO)
LY-2157299  (ISO)
magnesium atom  (ISO)
malonaldehyde  (ISO)
mangiferin  (EXP)
manidipine  (EXP)
maraviroc  (ISO)
marinobufagenin  (EXP)
menadione  (ISO)
menaquinone  (ISO)
mercaptopurine  (EXP)
mercury dibromide  (ISO)
mercury dichloride  (EXP)
methotrexate  (ISO)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
methylmercury(1+)  (EXP)
methylparaben  (ISO)
metoprolol  (EXP,ISO)
miconazole  (ISO)
mifepristone  (EXP)
monocrotaline  (EXP)
monosodium L-glutamate  (EXP)
myricitrin  (ISO)
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine  (ISO)
N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide  (ISO)
N-acetyl-1,4-benzoquinone imine  (ISO)
N-acetyl-L-cysteine  (EXP,ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (EXP)
N-methyl-4-phenylpyridinium  (EXP)
N-nitrosodiethylamine  (EXP)
N-nitrosodimethylamine  (EXP)
N-nitrosomorpholine  (EXP)
N-oleoyldopamine  (ISO)
N-palmitoyl dopamine  (ISO)
N-tosyl-L-phenylalanyl chloromethyl ketone  (EXP)
naphthalene  (ISO)
naringin  (ISO)
neoeriocitrin  (ISO)
nickel atom  (ISO)
nickel sulfate  (ISO)
Niclosamide  (ISO)
nicotinamide  (EXP,ISO)
nicotine  (ISO)
nimodipine  (ISO)
nitrofen  (EXP)
obeticholic acid  (EXP,ISO)
okadaic acid  (EXP)
olanzapine  (ISO)
olaparib  (ISO)
oleamide  (ISO)
oleanolic acid  (EXP)
oleic acid  (ISO)
Olmesartan medoxomil  (EXP)
Osajin  (ISO)
ouabain  (EXP)
oxaliplatin  (EXP)
ozone  (EXP,ISO)
paclitaxel  (ISO)
pamidronate  (ISO)
panobinostat  (ISO)
paracetamol  (ISO)
paraquat  (EXP,ISO)
parathion  (ISO)
paricalcitol  (ISO)
pentanal  (ISO)
Pentoxifylline  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (EXP)
perfluorooctanoic acid  (ISO)
phenobarbital  (EXP)
phenol  (ISO)
phenylmercury acetate  (ISO)
phenytoin  (ISO)
phosphatidylcholine  (EXP)
phosphorus atom  (ISO)
phosphorus(.)  (ISO)
pirfenidone  (EXP,ISO)
pirinixic acid  (EXP,ISO)
piroxicam  (ISO)
Plantamajoside  (ISO)
poly(ethylene)  (ISO)
poly(guanylic acid)  (EXP)
Pomiferin  (ISO)
potassium dichromate  (ISO)
prednisolone  (ISO)
Pristimerin  (EXP)
progesterone  (ISO)
propanal  (ISO)
prostaglandin E2  (ISO)
Ptaquiloside  (ISO)
puerarin  (ISO)
purine-6-thiol  (EXP)
pyrazinecarboxamide  (EXP)
pyrogallol  (ISO)
pyrrolidine dithiocarbamate  (EXP)
quartz  (ISO)
quercetin  (EXP,ISO)
ramipril  (EXP)
Rebamipide  (EXP)
resveratrol  (EXP,ISO)
rifaximin  (ISO)
rosmarinic acid  (EXP,ISO)
rotenone  (EXP)
rottlerin  (ISO)
S-adenosyl-L-homocysteine  (ISO)
S-adenosyl-L-methioninate  (ISO)
S-adenosyl-L-methionine  (ISO)
S-butyl-DL-homocysteine (S,R)-sulfoximine  (EXP)
saralasin  (ISO)
SB 203580  (EXP,ISO)
SB 431542  (ISO)
Se-methyl-L-selenocysteine  (ISO)
Se-methylselenocysteine  (ISO)
selenium atom  (ISO)
serpentine asbestos  (ISO)
Shikonin  (ISO)
sildenafil citrate  (ISO)
silibinin  (EXP)
silicon dioxide  (EXP,ISO)
simvastatin  (ISO)
sirolimus  (EXP)
sirtinol  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (EXP,ISO)
sodium aurothiomalate  (ISO)
sodium chloride  (ISO)
sodium dichromate  (EXP)
sodium fluoride  (EXP)
sorafenib  (EXP,ISO)
stattic  (ISO)
streptozocin  (ISO)
sulfasalazine  (EXP)
sulforaphane  (ISO)
sunitinib  (EXP,ISO)
T-2 toxin  (ISO)
tacrolimus hydrate  (ISO)
tamoxifen  (ISO)
temozolomide  (ISO)
terbufos  (ISO)
testosterone  (EXP,ISO)
testosterone enanthate  (ISO)
testosterone undecanoate  (ISO)
tetrachloromethane  (EXP,ISO)
tetramethylpyrazine  (EXP,ISO)
tetraphene  (ISO)
thalidomide  (EXP)
theophylline  (ISO)
thioacetamide  (EXP,ISO)
thymoquinone  (ISO)
titanium atom  (EXP,ISO)
titanium dioxide  (ISO)
toluene  (EXP)
topotecan  (EXP)
tranexamic acid  (ISO)
tributylstannane  (EXP)
trichloroethene  (EXP,ISO)
trichostatin A  (ISO)
triclosan  (ISO)
trimellitic anhydride  (ISO)
troglitazone  (EXP,ISO)
uranium atom  (ISO)
valproic acid  (ISO)
valsartan  (ISO)
vanadium atom  (ISO)
vanadium(0)  (ISO)
verapamil  (ISO)
vitamin E  (EXP)
vitamin K  (EXP)
warfarin  (EXP,ISO)
Y-27632  (ISO)
zinc atom  (EXP,ISO)
zinc dichloride  (ISO)
zinc sulfate  (ISO)
zinc(0)  (EXP,ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
blood vessel development  (IBA,ISO)
bone trabecula formation  (ISO)
cartilage development involved in endochondral bone morphogenesis  (ISO)
cellular response to amino acid stimulus  (ISO)
cellular response to epidermal growth factor stimulus  (IEP)
cellular response to fibroblast growth factor stimulus  (IEP)
cellular response to fluoride  (IEP)
cellular response to mechanical stimulus  (IEP,ISO)
cellular response to retinoic acid  (IEP)
cellular response to transforming growth factor beta stimulus  (IEP)
cellular response to tumor necrosis factor  (IEP)
cellular response to vitamin E  (IEP)
collagen biosynthetic process  (ISO)
collagen fibril organization  (ISO)
collagen-activated tyrosine kinase receptor signaling pathway  (IBA,IDA)
embryonic skeletal system development  (ISO)
endochondral ossification  (ISO)
extracellular matrix organization  (IBA)
face morphogenesis  (ISO)
intramembranous ossification  (ISO)
negative regulation of cell-substrate adhesion  (ISO)
ossification  (IBA,IEP)
osteoblast differentiation  (ISO)
positive regulation of canonical Wnt signaling pathway  (ISO)
positive regulation of cell migration  (ISO)
positive regulation of epithelial to mesenchymal transition  (ISO)
positive regulation of transcription, DNA-templated  (ISO)
protein localization to nucleus  (ISO)
protein transport  (ISO)
response to cAMP  (IEP)
response to corticosteroid  (IEP)
response to drug  (IEP)
response to estradiol  (IEP)
response to fluoride  (IEP)
response to hydrogen peroxide  (IEP)
response to hyperoxia  (IEP)
response to mechanical stimulus  (IBA,IEP)
response to nutrient  (IEP)
response to nutrient levels  (IEP)
response to peptide hormone  (IEP)
response to steroid hormone  (IEP)
sensory perception of sound  (ISO)
skeletal system development  (IBA,ISO)
skeletal system morphogenesis  (ISO)
skin development  (IBA,ISO)
skin morphogenesis  (ISO)
tooth eruption  (IEP)
tooth mineralization  (ISO)
visual perception  (ISO)
wound healing  (IMP)

Cellular Component

Molecular Function


References - curated
1. Abrahamsen CT, etal., J Pharmacol Exp Ther. 2002 Apr;301(1):21-8. doi: 10.1124/jpet.301.1.21.
2. Aerssens J, etal., Arthritis Rheum. 1998 Nov;41(11):1946-50.
3. Ahmed MR, etal., Osteoarthritis Cartilage. 2014 Nov;22(11):1894-901. doi: 10.1016/j.joca.2014.07.028. Epub 2014 Aug 13.
4. Almeida L, etal., Infect Genet Evol. 2015 Mar;30:225-9. doi: 10.1016/j.meegid.2014.12.034. Epub 2015 Jan 3.
5. Annoni G, etal., Boll Ist Sieroter Milan. 1991-1992;70(1-2):391-7.
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Additional References at PubMed
PMID:1874719   PMID:2209468   PMID:2779548   PMID:4126850   PMID:4290711   PMID:4327399   PMID:4335087   PMID:4342027   PMID:4366532   PMID:4636751   PMID:5337886   PMID:5411206  
PMID:5777344   PMID:6395893   PMID:7573384   PMID:7589890   PMID:7629088   PMID:7704020   PMID:7790374   PMID:8018053   PMID:8097422   PMID:8130375   PMID:8163675   PMID:8686743  
PMID:8889548   PMID:8900172   PMID:8906420   PMID:8984825   PMID:9213002   PMID:10065941   PMID:10608859   PMID:10878613   PMID:12199527   PMID:12477932   PMID:12647294   PMID:14630726  
PMID:14749390   PMID:14976317   PMID:15095409   PMID:15383546   PMID:15647278   PMID:15677443   PMID:15703183   PMID:16306131   PMID:16311053   PMID:16751282   PMID:16938497   PMID:16971509  
PMID:17018525   PMID:17029294   PMID:17118335   PMID:17156988   PMID:17206378   PMID:17211858   PMID:17440987   PMID:17485851   PMID:17576241   PMID:17616939   PMID:17662583   PMID:17924680  
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PMID:29286102   PMID:29733741   PMID:30053369   PMID:31186140  


Comparative Map Data
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01082,745,801 - 82,762,790 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1082,745,801 - 82,762,789 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01082,563,434 - 82,580,364 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41083,622,438 - 83,639,368 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11083,636,918 - 83,653,733 (+)NCBI
Celera1078,658,450 - 78,675,438 (+)NCBICelera
Cytogenetic Map10q26NCBI
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl1750,183,289 - 50,201,632 (-)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl1750,184,101 - 50,201,632 (-)EnsemblGRCh38hg38GRCh38
GRCh381750,184,096 - 50,201,649 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371748,261,457 - 48,279,003 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361745,616,456 - 45,633,999 (-)NCBINCBI36hg18NCBI36
Build 341745,616,455 - 45,633,992NCBI
Celera1744,722,303 - 44,739,829 (-)NCBI
Cytogenetic Map17q21.33NCBI
HuRef1743,630,129 - 43,647,463 (-)NCBIHuRef
CHM1_11748,325,754 - 48,343,284 (-)NCBICHM1_1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm391194,827,050 - 94,843,868 (+)NCBIGRCm39mm39
GRCm381194,936,224 - 94,953,042 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1194,936,224 - 94,953,042 (+)EnsemblGRCm38mm10