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Gene: Col1a1 (collagen, type I, alpha 1) Mus musculus
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Symbol: Col1a1
Name: collagen, type I, alpha 1
Description: Exhibits extracellular matrix structural constituent and identical protein binding activity. Involved in several processes, including cellular response to mechanical stimulus; face morphogenesis; and skeletal system morphogenesis. Localizes to the collagen type I trimer and cytoplasm. Used to study Ehlers-Danlos syndrome and osteogenesis imperfecta (multiple). Human ortholog(s) of this gene implicated in several diseases, including beta thalassemia; bone disease (multiple); cutaneous leishmaniasis; dermatofibrosarcoma protuberans; and tooth disease (multiple). Is expressed in several structures, including alimentary system; embryo mesenchyme; eye; heart and pericardium; and skeleton. Orthologous to human COL1A1 (collagen type I alpha 1 chain).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: alpha-1 type 1 collagen; alpha-1 type I collagen; Col1a-1; Cola-1; Cola1; collagen alpha-1(I) chain; Mov-13; Mov13; procollagen, type I, alpha 1
Orthologs:
Homo sapiens (human) : COL1A1 (collagen type I alpha 1 chain)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Col1a1 (collagen type I alpha 1 chain)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Col1a1 (collagen type I alpha 1 chain)
Pan paniscus (bonobo/pygmy chimpanzee) : COL1A1 (collagen type I alpha 1 chain)
Canis lupus familiaris (dog) : COL1A1 (collagen type I alpha 1 chain)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Col1a1 (collagen type I alpha 1 chain)
Sus scrofa (pig) : COL1A1 (collagen type I alpha 1 chain)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm381194,936,224 - 94,953,042 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371194,797,584 - 94,813,181 (+)NCBIGRCm37mm9NCBIm37
MGSCv361194,752,360 - 94,767,957 (+)NCBImm8
Celera11104,549,617 - 104,565,301 (+)NCBICelera
Cytogenetic Map11 DNCBI
cM Map1159.01NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences