Slc25a10 (solute carrier family 25 member 10)

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Gene: Slc25a10 (solute carrier family 25 member 10) Rattus norvegicus

Analyze

Symbol:

Slc25a10

Name:

solute carrier family 25 member 10

RGD ID:

621430

Description:

Enables several functions, including C4-dicarboxylate transmembrane transporter activity; phosphate ion transmembrane transporter activity; and sulfur compound transmembrane transporter activity. Involved in several processes, including C4-dicarboxylate transport; sulfate transport; and thiosulfate transport. Predicted to be located in mitochondrion and nucleoplasm. Predicted to be active in mitochondrial inner membrane. Human ortholog(s) of this gene implicated in mitochondrial DNA depletion syndrome 19. Orthologous to human SLC25A10 (solute carrier family 25 member 10); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,2,2-tetramine.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

Dic; dicarboxylate transporter), member 10; MGC93224; mitochondrial dicarboxylate carrier; solute carrier family 25 (mitochondrial carrier; solute carrier family 25 (mitochondrial carrier, dicarboxylate transporter), member 10; solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	SLC25A10 (solute carrier family 25 member 10)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Slc25a10 (solute carrier family 25 (mitochondrial carrier, dicarboxylate transporter), member 10)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Slc25a10 (solute carrier family 25 member 10)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	SLC25A10 (solute carrier family 25 member 10)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	SLC25A10 (solute carrier family 25 member 10)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Slc25a10 (solute carrier family 25 member 10)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	SLC25A10 (solute carrier family 25 member 10)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	SLC25A10 (solute carrier family 25 member 10)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Slc25a10 (solute carrier family 25 member 10)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	PI4KA (phosphatidylinositol 4-kinase alpha)	HGNC	OMA
Alliance orthologs ³
Mus musculus (house mouse):	Slc25a10 (solute carrier family 25 (mitochondrial carrier, dicarboxylate transporter), member 10)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	SLC25A10 (solute carrier family 25 member 10)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	si:ch1073-100f3.2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)
Danio rerio (zebrafish):	slc25a10 (solute carrier family 25 member 10)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	DIC1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Dic1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Dic2	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER\|PhylomeDB)
Drosophila melanogaster (fruit fly):	Dic3	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER)
Drosophila melanogaster (fruit fly):	Dic4	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER)
Caenorhabditis elegans (roundworm):	slc-25A10	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	slc25a10	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	10	105,765,598 - 105,775,159 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	105,765,372 - 105,773,556 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	10	110,870,210 - 110,877,669 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	110,333,241 - 110,340,700 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	105,686,517 - 105,693,978 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	109,665,682 - 109,674,782 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	109,665,682 - 109,673,143 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	10	109,258,950 - 109,268,049 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	10	109,877,811 - 109,885,272 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	10	109,892,314 - 109,899,776 (+)	NCBI
Celera	10	104,309,989 - 104,317,450 (+)	NCBI		Celera
Cytogenetic Map	10	q32.3	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Animal Mammary Neoplasms (ISO)

carcinoma (ISO)

Experimental Mammary Neoplasms (ISO)

genetic disease (ISO)

mitochondrial complex I deficiency (ISO)

mitochondrial DNA depletion syndrome 19 (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

(1->4)-beta-D-glucan (ISO)

1,1-dichloroethene (ISO)

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (ISO)

17beta-estradiol (EXP,ISO)

2,2,2-tetramine (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

3,3',4,4',5-pentachlorobiphenyl (EXP)

3-isobutyl-1-methyl-7H-xanthine (ISO)

3H-1,2-dithiole-3-thione (EXP)

4,4'-diaminodiphenylmethane (ISO)

4,4'-sulfonyldiphenol (EXP,ISO)

4-hydroxyphenyl retinamide (ISO)

6-propyl-2-thiouracil (EXP)

7,12-dimethyltetraphene (EXP)

acrylamide (ISO)

aflatoxin B1 (EXP,ISO)

aldehydo-D-glucose (EXP)

all-trans-retinoic acid (ISO)

amitrole (EXP)

ammonium chloride (EXP)

amphetamine (EXP)

aristolochic acid A (ISO)

atrazine (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

bisphenol F (EXP)

cadmium atom (ISO)

cadmium dichloride (ISO)

chlordecone (ISO)

chlorpyrifos (ISO)

ciguatoxin CTX1B (ISO)

cisplatin (EXP,ISO)

clofibrate (ISO)

clofibric acid (EXP)

copper atom (ISO)

copper(0) (ISO)

cyclosporin A (ISO)

D-glucose (EXP)

dexamethasone (ISO)

dextran sulfate (ISO)

dibutyl phthalate (ISO)

dichloroacetic acid (ISO)

dioxygen (ISO)

dorsomorphin (ISO)

endosulfan (EXP)

enzyme inhibitor (ISO)

epoxiconazole (ISO)

ethanol (ISO)

formaldehyde (ISO)

glucose (EXP)

glutathione (EXP)

indometacin (ISO)

inulin (ISO)

isoprenaline (ISO)

malonic acid (EXP)

methimazole (EXP)

monosodium L-glutamate (ISO)

N,N-diethyl-m-toluamide (EXP)

N-nitrosodiethylamine (EXP)

N-Nitrosopyrrolidine (ISO)

obeticholic acid (ISO)

paracetamol (EXP,ISO)

perfluorooctane-1-sulfonic acid (EXP,ISO)

permethrin (EXP)

PhIP (EXP)

pirinixic acid (ISO)

pregnenolone 16alpha-carbonitrile (EXP)

progesterone (ISO)

propiconazole (EXP)

Pyridostigmine bromide (EXP)

raloxifene (EXP)

resveratrol (EXP)

S-(1,2-dichlorovinyl)-L-cysteine (EXP)

SB 431542 (ISO)

sodium arsenite (ISO)

sodium fluoride (ISO)

streptozocin (EXP)

sulfadimethoxine (EXP)

temozolomide (ISO)

tert-butyl hydroperoxide (EXP,ISO)

tetrachloromethane (EXP,ISO)

tetrahydropalmatine (ISO)

thapsigargin (ISO)

thioacetamide (EXP)

titanium dioxide (EXP,ISO)

triphenyl phosphate (EXP)

troglitazone (ISO)

trovafloxacin (ISO)

tunicamycin (ISO)

urethane (ISO)

valproic acid (ISO)

vancomycin (ISO)

vinclozolin (EXP)

zidovudine (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

glyceraldehyde-3-phosphate biosynthetic process (IEA,ISO)

lipid transport (IEA)

malate transmembrane transport (IBA)

malate transport (IDA)

mitochondrial transport (IEA)

oxaloacetate transport (IBA)

oxaloacetate(2-) transmembrane transport (IEA)

phosphate ion transmembrane transport (IBA)

phosphate ion transport (IDA)

succinate transmembrane transport (IBA)

succinate transport (IDA)

sulfate transmembrane transport (IEA)

sulfate transport (IBA,IDA)

thiosulfate transport (IBA,IDA)

Cellular Component

membrane (IEA)

mitochondrial inner membrane (IEA,ISO)

mitochondrion (ISO)

nucleoplasm (IEA,ISO)

Molecular Function

antiporter activity (IBA,IDA)

dicarboxylic acid transmembrane transporter activity (ISO)

malate transmembrane transporter activity (IBA,IDA,ISO)

oxaloacetate transmembrane transporter activity (IBA)

phosphate ion transmembrane transporter activity (IDA)

protein binding (ISO)

secondary active transmembrane transporter activity (ISO)

succinate transmembrane transporter activity (IBA,IDA)

sulfate transmembrane transporter activity (IBA,IDA)

thiosulfate transmembrane transporter activity (IBA,IDA)

References

References - curated

#	Reference Title	Reference Citation
1.	The sequence, bacterial expression, and functional reconstitution of the rat mitochondrial dicarboxylate transporter cloned via distant homologs in yeast and Caenorhabditis elegans.	Fiermonte G, etal., J Biol Chem 1998 Sep 18;273(38):24754-9.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
4.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
5.	Identification by bacterial expression and functional reconstitution of the yeast genomic sequence encoding the mitochondrial dicarboxylate carrier protein.	Palmieri L, etal., FEBS Lett 1996 Dec 16;399(3):299-302.
6.	GOA pipeline	RGD automated data pipeline
7.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
8.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Additional References at PubMed

PMID:10567211	PMID:12865426	PMID:14651853	PMID:18614015	PMID:20538765	PMID:20949348	PMID:21630459	PMID:24625528

Genomics

Comparative Map Data

Slc25a10
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	10	105,765,598 - 105,775,159 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	105,765,372 - 105,773,556 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	10	110,870,210 - 110,877,669 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	110,333,241 - 110,340,700 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	105,686,517 - 105,693,978 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	109,665,682 - 109,674,782 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	109,665,682 - 109,673,143 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	10	109,258,950 - 109,268,049 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	10	109,877,811 - 109,885,272 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	10	109,892,314 - 109,899,776 (+)	NCBI
Celera	10	104,309,989 - 104,317,450 (+)	NCBI		Celera
Cytogenetic Map	10	q32.3	NCBI

SLC25A10
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	17	81,712,284 - 81,721,012 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	17	81,712,236 - 81,721,016 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	17	79,679,314 - 79,688,042 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	17	77,289,776 - 77,298,447 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	17	77,289,775 - 77,298,446	NCBI
Celera	17	76,324,691 - 76,333,300 (+)	NCBI		Celera
Cytogenetic Map	17	q25.3	NCBI
HuRef	17	75,125,159 - 75,133,942 (+)	NCBI		HuRef
CHM1_1	17	79,765,485 - 79,774,259 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	17	82,629,200 - 82,637,941 (+)	NCBI		T2T-CHM13v2.0

Slc25a10
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	120,382,663 - 120,391,987 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	11	120,382,666 - 120,390,013 (+)	Ensembl		GRCm39 Ensembl
GRCm38	11	120,491,837 - 120,501,161 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	120,491,840 - 120,499,187 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	11	120,353,151 - 120,362,475 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	11	120,307,962 - 120,315,256 (+)	NCBI		MGSCv36	mm8
Celera	11	132,227,169 - 132,236,494 (+)	NCBI		Celera
Cytogenetic Map	11	E2	NCBI
cM Map	11	84.19	NCBI

Slc25a10
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955506	1,385,788 - 1,397,015 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955506	1,389,798 - 1,396,670 (-)	NCBI	ChiLan1.0	ChiLan1.0

SLC25A10
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1	17	103,202,842 - 103,211,573 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	17	76,171,759 - 76,180,484 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	17	81,874,036 - 81,882,607 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	17	81,875,710 - 81,882,106 (+)	Ensembl	panpan1.1		panPan2

SLC25A10
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	9	483,864 - 491,613 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	9	1,086,046 - 1,093,795 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	9	1,077,336 - 1,085,083 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	9	1,077,341 - 1,084,351 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	9	1,102,327 - 1,110,046 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	9	1,228,913 - 1,236,632 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	9	1,307,913 - 1,315,661 (-)	NCBI		UU_Cfam_GSD_1.0

Slc25a10
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	1,097,004 - 1,103,454 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936594	5,308,464 - 5,317,239 (+)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936594	5,308,623 - 5,314,955 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SLC25A10
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	12	1,189,903 - 1,197,301 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	12	1,191,242 - 1,197,439 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

SLC25A10
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	16	73,643,633 - 73,652,746 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	16	73,643,814 - 73,655,591 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666077	45,051,567 - 45,060,751 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Slc25a10
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624801	10,643,123 - 10,649,651 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624801	10,643,198 - 10,649,651 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Slc25a10
55 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	340
Count of miRNA genes:	179
Interacting mature miRNAs:	200
Transcripts:	ENSRNOT00000054963
Prediction methods:	Microtar, Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2316949	Gluco60	Glucose level QTL 60	3.7		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	10	14487011	107057807	Rat
1331791	Cm31	Cardiac mass QTL 31	3.84606		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	10	29299504	107211142	Rat
61387	Bp1	Blood pressure QTL 1	5.1		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	51770177	107211142	Rat
61387	Bp1	Blood pressure QTL 1	5.1		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	10	51770177	107211142	Rat
70171	Cari1	Carrageenan-induced inflammation QTL 1	4.9	0.0005	hypodermis integrity trait (VT:0010550)	inflammatory exudate volume (CMO:0001429)	10	53797385	107211142	Rat
2313103	Bss80	Bone structure and strength QTL 80	2	0.0001	tibia strength trait (VT:1000284)	tibia midshaft endosteal cross-sectional area (CMO:0001716)	10	62057807	107057807	Rat
2313105	Bss79	Bone structure and strength QTL 79	1.8	0.0001	tibia size trait (VT:0100001)	tibia midshaft cross-sectional area (CMO:0001717)	10	62057807	107057807	Rat
61449	Ciaa2	CIA Autoantibody QTL 2	7.1		blood autoantibody amount (VT:0003725)	calculated serum anti-type 2 collagen antibody titer (CMO:0001279)	10	63221094	107211142	Rat
2317029	Aia19	Adjuvant induced arthritis QTL 19	2.98		joint integrity trait (VT:0010548)	left rear ankle joint diameter (CMO:0002149)	10	66978955	107211142	Rat
2317039	Aia6	Adjuvant induced arthritis QTL 6	4.31		joint integrity trait (VT:0010548)	right rear ankle joint diameter (CMO:0002150)	10	66978955	107211142	Rat
10450498	Bp384	Blood pressure QTL 384		0.002	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	67750049	107211142	Rat
1642980	Bp300	Blood pressure QTL 300			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	68383129	107211142	Rat
61396	Bp9	Blood pressure QTL 9	4.8	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	68420376	107211142	Rat
2300172	Bmd57	Bone mineral density QTL 57	9.8	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	10	69738412	107211142	Rat
2293646	Bss25	Bone structure and strength QTL 25	10.96	0.0001	femur morphology trait (VT:0000559)	femur cross-sectional area (CMO:0001661)	10	69738412	107211142	Rat
2293663	Bss33	Bone structure and strength QTL 33	9.34	0.0001	femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	10	69738412	107211142	Rat
6893366	Bw106	Body weight QTL 106	0.3	0.47	body mass (VT:0001259)	body weight (CMO:0000012)	10	70199100	107211142	Rat
70193	Mcs7	Mammary carcinoma susceptibility QTL 7	2.38		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	10	72224939	107211142	Rat
2298548	Neuinf7	Neuroinflammation QTL 7	3.4		nervous system integrity trait (VT:0010566)	spinal cord RT1-B protein level (CMO:0002132)	10	72224939	107211142	Rat
2292438	Bp311	Blood pressure QTL 311			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	76246085	107211142	Rat
1302404	Cia27	Collagen induced arthritis QTL 27	2.6	0.0045	joint integrity trait (VT:0010548)	experimental arthritis severity measurement (CMO:0001459)	10	76452683	107211142	Rat
4889492	Pancm2	Pancreatic morphology QTL 2	3.2		pancreatic beta cell morphology trait (VT:0005217)	ratio of insulin-positive cell area to total area of splenic region of pancreas (CMO:0001814)	10	76748906	107211142	Rat
2303589	Bw87	Body weight QTL 87	2		body mass (VT:0001259)	body weight (CMO:0000012)	10	81285008	107211142	Rat
2317754	Glom25	Glomerulus QTL 25	3.5		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	10	82685200	107211142	Rat
631538	Oia5	Oil induced arthritis QTL 5			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	87055121	107211142	Rat
61363	Oia3	Oil induced arthritis QTL 3		0.001	joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	87307617	107211142	Rat
634320	Niddm49	Non-insulin dependent diabetes mellitus QTL 49	4.41		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	10	88539139	107211142	Rat
12880395	Cm109	Cardiac mass QTL 109		0.001	heart right ventricle mass (VT:0007033)	heart right ventricle weight to body weight ratio (CMO:0000914)	10	90404397	107211142	Rat
12880396	Am13	Aortic mass QTL 13		0.001	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	10	90404397	107211142	Rat
12880398	Kidm67	Kidney mass QTL 67		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	10	90404397	107211142	Rat
12880384	Cm107	Cardiac mass QTL 107		0.001	heart mass (VT:0007028)	heart wet weight to body weight ratio (CMO:0002408)		90404397	107211142	Rat
12880385	Cm108	Cardiac mass QTL 108		0.001	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)		90404397	107211142	Rat
1579915	Bp280	Blood pressure QTL 280		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	90404397	107211142	Rat
1300137	Bp186	Blood pressure QTL 186	3.57		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	10	90627439	107057807	Rat
724530	Bp149	Blood pressure QTL 149		0.0001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	90627439	107211142	Rat
1558652	Bw57	Body weight QTL 57	4.2	0.0008	body mass (VT:0001259)	body weight (CMO:0000012)	10	90910316	107211142	Rat
1354641	Bvd2	Brain ventricular dilatation QTL 2	6.36	0.001	brain ventricle morphology trait (VT:0000822)	hydrocephalus severity score (CMO:0001881)	10	93223816	107057807	Rat
10450493	Bp382	Blood pressure QTL 382		0.002	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	94759759	107211142	Rat
2292436	Bp310	Blood pressure QTL 310			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	94759759	107211142	Rat
1578663	Bss18	Bone structure and strength QTL 18	3.6		femur width (VT:1000666)	femoral neck width (CMO:0001695)	10	96703043	107057807	Rat
1578672	Bmd16	Bone mineral density QTL 16	6.2		femur mineral mass (VT:0010011)	compact volumetric bone mineral density (CMO:0001730)	10	96703043	107057807	Rat

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	3	32	52	41	12	41			66	35	39	9
Low		11	5		7		8	11	8		2	2	8
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_133418	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017596977	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039085120	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC131537	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AJ223355	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC081734	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473948	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000220	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000054963 ⟹ ENSRNOP00000051846

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	10	105,765,979 - 105,773,556 (+)	Ensembl
Rnor_6.0 Ensembl	10	109,665,682 - 109,673,143 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000103059 ⟹ ENSRNOP00000087842

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	10	105,765,979 - 105,772,499 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000106118 ⟹ ENSRNOP00000078001

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	10	105,765,372 - 105,773,556 (+)	Ensembl

RefSeq Acc Id:

NM_133418 ⟹ NP_596909

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	10	105,766,060 - 105,773,521 (+)	NCBI
Rnor_6.0	10	109,665,682 - 109,673,143 (+)	NCBI
Rnor_5.0	10	109,258,950 - 109,268,049 (+)	NCBI
RGSC_v3.4	10	109,877,811 - 109,885,272 (+)	RGD
Celera	10	104,309,989 - 104,317,450 (+)	RGD

Sequence:

show sequence

CCGGGGTCGGGCCAGGTCGCTGCTGCTCTGGCCATGGCTGAGGCACGCACGTCTCGCTGGTACT
TTGGAGGGCTGGCTTCCTGCGGAGCTGCCTGCTGCACGCACCCTCTAGACCTGCTCAAGGTGCA
TTTGCAGACCCAACAGGAGGTGAAGCTTCGAATGACTGGAATGGCACTGCAGGTGGTGCGAACC
GATGGCTTCCTGGCACTCTACAATGGCCTGAGTGCCTCGCTGTGCAGGCAGATGACCTACTCCC
TGACCCGGTTCGCTATCTACGAGACCATGCGGGACTACATGACCAAGGACAGCCAGGGGCCTCT
CCCCTTCTACAGCAAGGTGTTGCTGGGCGGCATCAGTGGTTTAACTGGAGGCTTCGTGGGGACC
CCAGCAGATTTGGTCAATGTCAGGATGCAGAATGACATGAAGCTGCCTCTGAGCCAGCGCCGCA
ACTACTCTCACGCCCTGGATGGTCTGTACCGTGTAGCCCGTGAAGAAGGCCTGAAGAAGCTCTT
CTCTGGAGCAACTATGGCATCCAGCCGTGGGGCCCTCGTCACTGTGGGCCAGCTGTCCTGCTAC
GACCAGGCCAAGCAGCTGGTTCTCAGTACTGGGTACCTGAGTGACAACATTTTCACCCACTTCC
TCTCCAGTTTCATTGCGGGCGGATGTGCCACATTTCTCTGCCAGCCCCTGGACGTGCTGAAGAC
TCGCTTGATGAACTCCAAGGGCGAGTATCAGGGTGTTTTCCATTGTGCCGTGGAGACAGCAAAG
CTTGGACCACAGGCCTTTTTCAAGGGTCTCGTTCCTGCGGGCGTCCGTCTCGTCCCCCACACCG
TGCTTACCTTCATGTTCCTGGAGCAGCTGCGGAAGCACTTCGGTATCAAAGTGGCAACCTGACA
CCGCCAGGGACACCTGGGCTGCGCTCAGTCGCTGTGCTGAGCCCCTTGGAAGAGTAGGAAGGGA
GTGGGCTCCCTTCCTCCTTGGCCTGGGCCCGTGCTGATCCCCAGAAGATTCCTGTTCTTCCCAC
CCTTGGGCTGCTGGCTACGCCTTCCGACCCTGCCTTGGCCCCACTGAAGTGGCACCTCTGCCCT
ACTGGCTCCCAGGCTCTCCCCACTGGGACGTCCCATCTTCCTACCCGATGATTCACTCAGAAGA
GGTCTGGCCTGGCTGGTGTCACTGTCCCCACCTCCCTGGCTGCTACCCTGCCCTGCCTGTCAAG
CCCGGAGAAGCTGAGTACACTTCCTGCTCTTGCTGGCCCACTGAACAGCTTCCACCCAGGACTT
GGGTAGTGTGGCAGGGTACAGCCCCTGGCAGCTTCTGCTTACCAAATGACTAGAGCACGCACGC
ACACACATACACACATGCACTTACGTCACAAGAGGGACCACCGTGCAGTGTTCTGGAAGGTAGT
GCCTTCAGGAGAGGGAACAGGGCAGCAGCACAGATCACCAGCAAACGCCATGACCGCGGAGTCC
GGAGAAAGTACCTGGGGTTCCCTGTGCACCTCCCGTGCTCAGCCTTGGCTGCTTTAAGAGTCAG
TTTTTGCGGAACCCTCCTACTCAGCAGCCACTACCATCATCAGGAACTGGCTGTGTCCCTCATA
CACCTGTGCCCTCCCTTGCCTGGCTTCCCCCAGGGCCAGGGGCTCATGCTGGAGCTGGGGCTAT
GATGGATTCATTTTATGTGTCCTCCTAGGACCTGTTTTCCCGTATGGCAGGGGTCACCCCTCAC
CATCCCTCAGGGTTCAAAGCAGCCTGTTTTCCCTCAAATTGGGGTTGTGTGTATATCAACGTGA
GGTTGGGCCCTGTGCCCGTTTGCCTCCCCTCAGCACCAGGCCCTCACCCAGGAGGTGCGGGAGG
TGGCAGTGGGCCCAGGGGCACTGCCTACATCTCTCTTCAGGATCTAATAAACCAAGTGGCCAAA
AAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_017596977 ⟹ XP_017452466

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	10	105,766,327 - 105,775,159 (+)	NCBI
Rnor_6.0	10	109,665,923 - 109,674,782 (+)	NCBI

Sequence:

show sequence

ACCGCCGGTGACGCCCACGACGGCCTGAGCCCCGGCTGCCCCGCTCTGCGCTGCTGGCCTTGGC
CCTGAGGGCGCCACTACGCTTACTTCCCGGTAGACAGCGGTGGAAAAATCCCCGGGGACCCTCT
GCAGCTGGCGTCCGCAGGTGACAGACAGCTAAGCCTCAGAGGGGACATCCGGTTCCTCAGTTTA
CCTGTTAGGTCCCCTCTCTCCCACTCCCGCCCCCGGTCCCCGTCTTAACAGATGGCTGTTAAGC
TTCAGCTCTGCGCTATAATACTTGTGTGAACTCGGCCACTCTGAGCCTTTCCTTGGCCACAAAC
ATCGGACAACTCTGGTTAAAGTTGTGCATATGCGCAGGTGTTGAGACCCAAAGACCAGCCTGGT
CGCTGCACACCAGAGCACTTCCACTGCCGGGTGCTTAACACCACCTACTGTGGGGGTTGGGGGA
TGGAAATCAAGGCAACAGGCCGGGTGGTGGTGTGACCTCGGTCATCTGCTTCTGTTTGATTCGT
TGCTATATTGGGATCAGCACCGTCCCTCGTGAACTAGGAGATCCTCAATTCATAGGGCTCTGAC
CAGTAAGATTGACCACCTCACCCCGAGAAACAAATGAGACTCGTGGTTTTGTGTAGTTTTGTTT
TGTTTTTTCCTTAAAATACTTTTAGTGCAAACTAAGACAGTTTCTTCCTGTTCCCCAGGGACAT
TCTCGGGGAATTTATTCCTGATTCTGTCTTACCACAGAGAACAAAGAACTTAACCCACTCTGCC
CAAGGGGTTCTGGCTGTTACTTCAGCCTGTGGGCGAGCATTCACCCTGGCTGCCACCTCCCTCA
TACACACACACACACACACACACACACACACACACACACACACACACACGATTGGCCCCTGAGG
TCTGAGCTGGTGGTCCAGCCTCAAGCAGTTTCTACTAGCTCAAGCGTCTAAACTAGTCTCTGAC
TCCTCTCAGGGACTGAATTTCCTAAGAAAGGTAATCACTTTTCTTTCTTTATCATTTATTTGTA
GCCCAGGCTTACCTTGAACTTGTCCTGTGCATAATGCTGGCTTTGGACTCCTGCTTCTGCCCTC
CATGTGCAGAGATTTCAGGCACCCATTATCCCTCCCAGATAGCTTTTCGAATTACTGGCCATTG
GGTACACGTGAGGACTGAAACCTCACGTTTCCTGGGAGCAGAACAACCAGGTCCAACCCCTGGG
CATTGCCTCTGTCATGTATTATATCAGGAAGAGGAAGGTACTGATTGTTCTAGGAGGAACTTCT
TGACTGTATTTTCCTTTCCTAAATGTACCTGCAGCCTTCTCCGTCATGGGGATCGATCGGGCTA
GCTCGCTAACCCAGGCGTGGGCCCTGGAGACTCATTCACTTCACTCCTAGACAGTCCTTTTGGG
TGTTGATAGACTGTGACGTGAAAGTCCCAGGTGGTCATTCACTGTTCAAGTGCCCTCTGGGTTT
CACTGCTTCTCAGCCCCACCCCCACTCGGATGTTCTCTCGCTGCCCCGAGGAATGAGAAAGACT
GCTGTGAACGCGTGACCACTGGGACGGGTGCCAGTCGACAGTGGGCAGGGTATCCCAGTGAAGA
CTGCTCACGGAGACCATTCGAAAACTTGTATGATTTTGTTTTAAGAAGACAGGATCTTACTCTG
CCTCAGACTGACCTCAAACTCATGATCCTCCTGACTCCACCTGGGTGTTAGCATCATGTGCCTG
AGCTACTTGGTCAGCTCTGAAAAGGTGCATTTGCAGACCCAACAGGAGGTGAAGCTTCGAATGA
CTGGAATGGCACTGCAGGTGGTGCGAACCGATGGCTTCCTGGCACTCTACAATGGCCTGAGTGC
CTCGCTGTGCAGGCAGATGACCTACTCCCTGACCCGGTTCGCTATCTACGAGACCATGCGGGAC
TACATGACCAAGGACAGCCAGGGGCCTCTCCCCTTCTACAGCAAGGTGTTGCTGGGCGGCATCA
GTGGTTTAACTGGAGGCTTCGTGGGGACCCCAGCAGATTTGGTCAATGTCAGGATGCAGAATGA
CATGAAGCTGCCCCTGAGCCAGCGCCGCAACTACTCTCACGCCCTGGATGGTCTGTACCGTGTA
GCCCGTGAAGAAGGCCTGAAGAAGCTCTTCTCTGGAGCAACCATGGCATCCAGCCGTGGGGCCC
TCGTCACTGTGGGCCAGCTGTCCTGCTACGACCAGGCCAAGCAGCTGGTTCTCAGTACTGGGTA
CCTGAGTGACAACATTTTCACCCACTTCCTCTCCAGTTTCATTGCGGGCGGATGTGCCACATTT
CTCTGCCAGCCCCTGGACGTGCTGAAGACTCGCTTGATGAACTCCAAGGGCGAGTATCAGGGTG
TTTTCCATTGTGCCGTGGAGACAGCAAAGCTTGGACCACAGGCCTTTTTCAAGGGTCTCGTTCC
TGCGGGCGTCCGTCTCGTCCCCCACACCGTGCTTACCTTCATGTTCCTGGAGCAGCTGCGGAAG
CACTTCGGTATCAAAGTGGCAACCTGACACCGCCAGGGACACCTGGGCTGCGCTCAGTCGCTGT
GCTGAGCCCCTTGGAAGAGTAGGAAGGGAGTGGGCTCCCTTCCTCCTTGGCCTGGGCCCGTGCT
GATCCCTAGCAGATTCCTGTTCTTCCCACCCTTGGGCTGCTGGCTACGCCTTCCGACCCTGCCT
TGGCCCCACTGAAGTGGCACCTCTGCCCTACTGGCTCCCAGGCTCTCCCCACTGGGACGTCCCA
TCTTCCTACCCGATGATTCACTCAGAAGAGGTCTGGCCTGGCTGGTGTCACTGTCCCCACCTCC
CTGGCTGCTACCCTGCCCTGCCTGTCAAGCCCGGAGAAGCTGAGTACACTTCCTGCTCCTGCTG
GCCCACTGAACAGCTTCCACCCAGGACTTGGGTAGTGTGGCAGGGTACAGCCCCTGGCAGCTTC
TGCTTACCAAATGACTAGAGCACGCACGCACACACATACACGCATGCACTTACGTCACAAGAGG
GACCACCGTGCAGTGTTCTGGAAGGTAGTGCCTTCAGGAGAGGGAACAGGGCAGCAGCACAGAT
CACCAGCAAACGCCATGACCGCGGAGTCCGGAGAAAGTACCTGGGGTTCCCTGTGCACCTCCCG
TGCTCAGCGTTGGCTGCTTTAAGAGTCAGTTTTGCGGAACCCTCCTACTCAGCAGCCACTACCA
TCATCAGGAACTGGCTGTGTCCCTCATACACCTGTGCCCTCCCTTGCCTGGCTTCCCCCAGGGC
CAGGGGCTCATGCTGGAGCTGGGGCTATGATGGATTCATTCTATGTGTCCTCCTAGGACCTGTC
TTCCCGTATGGCAGGGGTCACCCCTCACCATCCCTCAGGCTTCAAAGCAGCCTGTTTTCCCTCA
AATTGGGGTTGTGTGTATATCAACGTGAGGTTGGGCCCTGTGCCCGTTTGCCTCCCCTCAGCAC
CAGGCCCTCACCCAGGAGGTGCAGGAGGTGGCAGTGGGCCCAGGGGCACTGCCTACATCTCTCT
TCAGGATCTAATAAACCAAGTGGCCTGGGAGGCTTCTCTCTTCCCTGCACACTCCTCACCCACT
CCGGGGCTGGCAGTTCTTTGAGCTTCTTCACCACTAAGGACAATGCTGTCTTGTCACTTTGAAT
CCACAAAATCAGAACCACTTGCATGGTAGAACCTATGGGGAGAATTCTTAGACAGTGGGCGGGA
GGAAAGGGAAATACCAACAGCAGCAGGTCTCTCTAGAGCCAGTCCCATGCAGTTGGTCGCTGGC
CAGCCAGCATAGAATTGAGGATGCCCTGGGGTCTATAATGAATGCCAACAGACTGAGAGGCCCA
GGCTATGGCAGTTGTACTGGCCTAGGCTGGGCCTAGGAGTATTCCAAGTATGTAAACAGAAGCA
GGATGTCAGCTAGGGGTACCAGGACCACAGCTCTGAATAAAACTTTACGCTTGGGTCAGAAGAA
ACCCAACTTCAGGAACCACAGCCCAGGTGCTATCGTGTCATAGGTAAACTCCAGAATACCTAAT
GACTAGACCTTGTGGGTACCAGGCTCTACGGTGTTGGGCCAAACCCTGGGCTTGGCCCTTGGTA
AACATGCACTGTGGCAGCCACATGGCCAGCCTCTCCTGTATACCTCACATGTGATACTCTGCCT
CCCCCTTCCCATTATAACTGTGGGCTAGCTCATCTAGATAGCAAGTTCCAGGCTAGCCAAGGCT
GTGTACGTTTTGTGGAACCTCGGTAGACTAGACTTGCACTCAAACATTGTCTCAAGGAAACAGA
AGTTTGTTCTGTGTGCAGTGGCTCATACCTACAATCCCTGCACATGAGAGGCAGATCACGTGTC
CAAGGCCAGCATTAGGTATTGAACAAGGTCCTGACTCAAGGGGGCAGGTGGGGTGCAGTTGTAA
GGTGTAACCCTAAAGCCCGTGGAGAAAATTAGACTGGCATTCCACCTGTTGGCCCACAAAACCA
GATTGCAACTTGGGTAAGCATTCTGGTTGGGATAGTGCAGGGGAGACACAGATGGAGCTGCTTC
TCCAGACCCCAGCCAACTTCCAAGAACTTGTCCCTAAACCAGAAACCACTAGCTGGTCAAACTT
ACAGAGCAGCTTTGGTTTGGAGCCTGGAGCAGGTCTTATCTGTGGCACCAGGGCTACTGGGGAA
ACTAATACTACACATGACTTTCCAAAATCTCCCTGGAGGTGAGAAAGTACCCAGTCTGGTTTGG
TGGGGTCAGGCCTGGCAACAGGCCCTGCAGGGCAAGGTGCATAAGCTAAGGTAGGCACCATGGT
CTCCCTACCACAGGGGAGGGCAGCTGGAAAAGCTTCCTACCCCTGCATGGAGAGCTACTGAGGG
GAAGGGGAAACAACTAGGGCAGGTCAGAGGACAGGCAGAGAGGGGTGCCATCCTAGGGGCCGTC
ACTCTTCACAGAGAGAGGAGAGCAGTGGGCTAGCCTCACTCCCATTGTTGTGTTGTAGGCTAAG
AGCTAATTTCCACTTGGACCCTGGGCACAGCTCCAAGGCCTGAGCCGTCAGCACTTTTCTGTCA
ACCTTAGGTCTTTTTTTCCTAAAGAATGACTTTATAGTTCACCAAAAAGTGAAAAGTTACTTTT
TACTGCCAGCAGAGGTGTCAGGACATGTGTACAAAGAAAAAAAAATAAAAAAACACTTCAAGTG

hide sequence

RefSeq Acc Id:

XM_039085120 ⟹ XP_038941048

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	10	105,765,598 - 105,770,686 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_596909	(Get FASTA)	NCBI Sequence Viewer
	XP_017452466	(Get FASTA)	NCBI Sequence Viewer
	XP_038941048	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH81734	(Get FASTA)	NCBI Sequence Viewer
	CAA11278	(Get FASTA)	NCBI Sequence Viewer
	EDM06844	(Get FASTA)	NCBI Sequence Viewer
	EDM06845	(Get FASTA)	NCBI Sequence Viewer
	EDM06846	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000051846
	ENSRNOP00000078001
	ENSRNOP00000078001.1
	ENSRNOP00000087842.1
GenBank Protein	O89035	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_596909 ⟸ NM_133418

- UniProtKB:

O89035 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAEARTSRWYFGGLASCGAACCTHPLDLLKVHLQTQQEVKLRMTGMALQVVRTDGFLALYNGLS
ASLCRQMTYSLTRFAIYETMRDYMTKDSQGPLPFYSKVLLGGISGLTGGFVGTPADLVNVRMQN
DMKLPLSQRRNYSHALDGLYRVAREEGLKKLFSGATMASSRGALVTVGQLSCYDQAKQLVLSTG
YLSDNIFTHFLSSFIAGGCATFLCQPLDVLKTRLMNSKGEYQGVFHCAVETAKLGPQAFFKGLV
PAGVRLVPHTVLTFMFLEQLRKHFGIKVAT

hide sequence

RefSeq Acc Id:	XP_017452466 ⟸ XM_017596977
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I5Y824 (UniProtKB/TrEMBL)
- Sequence:	show sequence MCLSYLVSSEKVHLQTQQEVKLRMTGMALQVVRTDGFLALYNGLSASLCRQMTYSLTRFAIYET MRDYMTKDSQGPLPFYSKVLLGGISGLTGGFVGTPADLVNVRMQNDMKLPLSQRRNYSHALDGL YRVAREEGLKKLFSGATMASSRGALVTVGQLSCYDQAKQLVLSTGYLSDNIFTHFLSSFIAGGC ATFLCQPLDVLKTRLMNSKGEYQGVFHCAVETAKLGPQAFFKGLVPAGVRLVPHTVLTFMFLEQ LRKHFGIKVAT hide sequence

RefSeq Acc Id:

ENSRNOP00000051846 ⟸ ENSRNOT00000054963

RefSeq Acc Id:	XP_038941048 ⟸ XM_039085120
- Peptide Label:	isoform X2
- UniProtKB:	A6HLE1 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSRNOP00000087842 ⟸ ENSRNOT00000103059

RefSeq Acc Id:

ENSRNOP00000078001 ⟸ ENSRNOT00000106118

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-O89035-F1-model_v2	AlphaFold	O89035	1-286	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13697960

Promoter ID:

EPDNEW_R8484

Type:

initiation region

Name:

Slc25a10_1

Description:

solute carrier family 25 member 10

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	10	109,665,601 - 109,665,661	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:621430	AgrOrtholog
BioCyc Gene	G2FUF-22425	BioCyc
Ensembl Genes	ENSRNOG00000036693	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000054963	ENTREZGENE, UniProtKB/Swiss-Prot
	ENSRNOT00000103059.1	UniProtKB/TrEMBL
	ENSRNOT00000106118	ENTREZGENE
	ENSRNOT00000106118.1	UniProtKB/TrEMBL
Gene3D-CATH	1.50.40.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7108552	IMAGE-MGC_LOAD
InterPro	Mit_uncoupling	UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
	Mitochondrial_sb/sol_carrier	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Mt_carrier_dom	UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
KEGG Report	rno:170943	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:93224	IMAGE-MGC_LOAD
NCBI Gene	170943	ENTREZGENE
PANTHER	MITOCHONDRIAL DICARBOXYLATE CARRIER	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	Mito_carr	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Slc25a10	PhenoGen
PRINTS	MTUNCOUPLING	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE	SOLCAR	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000036693	RatGTEx
Superfamily-SCOP	Mitoch_carrier	UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
UniProt	A0A8I5Y824	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6GFJ0_RAT	UniProtKB/TrEMBL
	A6HLE0_RAT	UniProtKB/TrEMBL
	A6HLE1	ENTREZGENE, UniProtKB/TrEMBL
	DIC_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-03-09	Slc25a10	solute carrier family 25 member 10	Slc25a10	solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-03-30	Slc25a10	solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10			Symbol and Name status set to approved	1299863	APPROVED
2002-08-07	Slc25a10	solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10			Symbol and Name status set to provisional	70820	PROVISIONAL

RGD Curation Notes

Note Type	Note	Reference
gene_process	participates in gluconeogenesis and ureogenesis,possibly acts as a substrate to the Krebs cycle	634162

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM