Exhibits ATP binding activity; galactokinase activity; and galactose binding activity. Involved in carbohydrate phosphorylation and galactose metabolic process. Predicted to localize to cytosol. Human ortholog(s) of this gene implicated in cataract and galactokinase deficiency. Orthologous to human GALK1 (galactokinase 1); PARTICIPATES IN galactokinase deficiency pathway; galactose metabolic pathway; galactosemia pathway; INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; acetamide.
[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of GALK1 mRNA
[Enzyme Inhibitors binds to and results in decreased activity of GALK1 protein] which results in decreased abundance of galactose-1-phosphate, [GALK1 protein results in increased metabolism of Galactose] which results in increased abundance of galactose-1-phosphate
[Clofibrate co-treated with Acetaminophen] affects the expression of GALK1 mRNA, PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of GALK1 mRNA]
[Enzyme Inhibitors binds to and results in decreased activity of GALK1 protein] which results in decreased abundance of galactose-1-phosphate, [GALK1 protein results in increased metabolism of Galactose] which results in increased abundance of galactose-1-phosphate
[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of GALK1 mRNA
[Enzyme Inhibitors binds to and results in decreased activity of GALK1 protein] which results in decreased abundance of galactose-1-phosphate, Enzyme Inhibitors binds to and results in decreased activity of GALK1 protein
[Sodium Glutamate co-treated with High Fructose Corn Syrup] results in increased expression of GALK1 mRNA, [Sodium Glutamate co-treated with Trans Fatty Acids] results in increased expression of GALK1 mRNA
[Clofibrate co-treated with Acetaminophen] affects the expression of GALK1 mRNA, PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of GALK1 mRNA]
[pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of GALK1 mRNA, PPARA protein promotes the reaction [pirinixic acid results in increased expression of GALK1 mRNA]
Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Gene-Chemical Interaction Annotations
