Galr2 (galanin receptor 2) - Rat Genome Database

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Gene: Galr2 (galanin receptor 2) Rattus norvegicus
Analyze
Symbol: Galr2
Name: galanin receptor 2
RGD ID: 2657
Description: Enables galanin receptor activity and neuropeptide binding activity. Involved in several processes, including adenylate cyclase-activating G protein-coupled receptor signaling pathway; inositol phosphate metabolic process; and phosphatidylinositol metabolic process. Located in plasma membrane. Orthologous to human GALR2 (galanin receptor 2); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: GAL2-R; galanin receptor type 2; GALR-2; LOC103690156
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
NCBI Annotation Information: Note: In Rnor_6.0 (AR 105), the loci 29234 and 103690156 are placed twice on chromosome 10. This is likely an assembly error and not a true gene duplication. [28 May 2015]
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.210101,513,689 - 101,517,176 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl10101,514,471 - 101,517,176 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx10106,571,364 - 106,573,793 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.010106,034,454 - 106,036,883 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.010101,435,666 - 101,438,094 (+)NCBIRnor_WKY
Rnor_6.010105,156,793 - 105,159,221 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl10105,156,632 - 105,237,611 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.010104,900,150 - 104,902,315 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.410106,394,006 - 106,396,171 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.110106,408,502 - 106,410,685 (+)NCBI
Celera10100,087,566 - 100,089,731 (+)NCBICelera
Cytogenetic Map10q32.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

References

References - curated
# Reference Title Reference Citation
1. Galanin enhances corticosterone secretion from dispersed rat adrenocortical cells through the activation of GAL-R1 and GAL-R2 receptors coupled to the adenylate cyclase-dependent signaling cascade. Andreis PG, etal., Int J Mol Med. 2007 Jan;19(1):149-55.
2. Two genes in the rat homologous to human NKG2. Berg SF, etal., Eur J Immunol 1998 Feb;28(2):444-50
3. Expression of GalR1 and GalR2 galanin receptor messenger ribonucleic acid in proopiomelanocortin neurons of the rat arcuate nucleus: effect of testosterone. Bouret S, etal., Endocrinology 2000 May;141(5):1780-94
4. Cloning, pharmacological characterization and distribution of a novel galanin receptor. Fathi Z, etal., Brain Res Mol Brain Res 1997 Nov;51(1-2):49-59.
5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
6. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
7. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
8. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
9. Medical College of Ohio's SSLP Data file transfer Rapp J, Dene H,Direct Electronic Data transfer Feb.(5)2001 . Medical College of Ohio Department of Physiology and Molecular Medicine.
10. GOA pipeline RGD automated data pipeline
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
12. Expression cloning of a rat hypothalamic galanin receptor coupled to phosphoinositide turnover. Smith KE, etal., J Biol Chem 1997 Sep 26;272(39):24612-6.
13. Differential intracellular signaling of the GalR1 and GalR2 galanin receptor subtypes. Wang S, etal., Biochemistry. 1998 May 12;37(19):6711-7.
14. Molecular cloning and pharmacological characterization of a new galanin receptor subtype. Wang S, etal., Mol Pharmacol 1997 Sep;52(3):337-43.
15. Visualization of a functionally enhanced GFP-tagged galanin R2 receptor in PC12 cells: constitutive and ligand-induced internalization. Xia S, etal., Proc Natl Acad Sci U S A. 2004 Oct 19;101(42):15207-12. Epub 2004 Oct 7.
Additional References at PubMed
PMID:9108306   PMID:9473722   PMID:9832121   PMID:12533601   PMID:15885774   PMID:15944003   PMID:15944004   PMID:16248891   PMID:16626647   PMID:17287581   PMID:17993248   PMID:18172432  
PMID:18272487   PMID:20974494   PMID:21496293   PMID:21894515   PMID:24517231   PMID:24602615   PMID:26666529   PMID:27349435   PMID:28062253   PMID:28154160   PMID:28378856   PMID:29928003  


Genomics

Comparative Map Data
Galr2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.210101,513,689 - 101,517,176 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl10101,514,471 - 101,517,176 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx10106,571,364 - 106,573,793 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.010106,034,454 - 106,036,883 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.010101,435,666 - 101,438,094 (+)NCBIRnor_WKY
Rnor_6.010105,156,793 - 105,159,221 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl10105,156,632 - 105,237,611 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.010104,900,150 - 104,902,315 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.410106,394,006 - 106,396,171 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.110106,408,502 - 106,410,685 (+)NCBI
Celera10100,087,566 - 100,089,731 (+)NCBICelera
Cytogenetic Map10q32.1NCBI
GALR2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381776,071,962 - 76,077,537 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1776,074,781 - 76,077,537 (+)EnsemblGRCh38hg38GRCh38
GRCh371774,070,862 - 74,073,618 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361771,582,487 - 71,585,168 (+)NCBINCBI36Build 36hg18NCBI36
Build 341771,582,486 - 71,585,168NCBI
Celera1770,664,718 - 70,667,399 (+)NCBICelera
Cytogenetic Map17q25.1NCBI
HuRef1769,499,823 - 69,502,494 (+)NCBIHuRef
CHM1_11774,135,817 - 74,138,498 (+)NCBICHM1_1
T2T-CHM13v2.01776,971,346 - 76,974,102 (+)NCBIT2T-CHM13v2.0
Galr2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911116,170,520 - 116,174,776 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl11116,171,765 - 116,174,764 (+)EnsemblGRCm39 Ensembl
GRCm3811116,280,106 - 116,283,950 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11116,280,939 - 116,283,938 (+)EnsemblGRCm38mm10GRCm38
MGSCv3711116,142,253 - 116,145,252 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3611116,097,029 - 116,100,005 (+)NCBIMGSCv36mm8
Celera11128,045,589 - 128,048,587 (+)NCBICelera
Cytogenetic Map11E2NCBI
cM Map1181.1NCBI
Galr2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555066,172,366 - 6,176,084 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555066,172,366 - 6,178,061 (-)NCBIChiLan1.0ChiLan1.0
GALR2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11775,578,072 - 75,580,806 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1775,578,072 - 75,580,806 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01770,019,383 - 70,028,689 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
GALR2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.194,559,710 - 4,562,474 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl94,560,067 - 4,562,463 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha95,240,420 - 5,242,990 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.095,230,227 - 5,232,798 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl95,230,403 - 5,232,798 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.195,270,157 - 5,272,724 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.095,379,443 - 5,382,005 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.095,440,143 - 5,442,711 (-)NCBIUU_Cfam_GSD_1.0
Galr2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244056025,172,746 - 5,175,859 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365941,236,061 - 1,239,113 (+)EnsemblSpeTri2.0
SpeTri2.0NW_0049365941,236,281 - 1,239,213 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GALR2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl125,359,582 - 5,363,095 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1125,360,232 - 5,364,396 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2125,262,826 - 5,267,911 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GALR2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11645,599,934 - 45,603,207 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1645,600,038 - 45,602,561 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607716,346,223 - 16,349,480 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Galr2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248015,983,254 - 5,985,596 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248015,982,870 - 5,987,756 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Galr2
10 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:195
Count of miRNA genes:119
Interacting mature miRNAs:128
Transcripts:ENSRNOT00000012523, ENSRNOT00000075548
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2303118Mamtr7Mammary tumor resistance QTL 70.003mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)109658275104670812Rat
631268Cia21Collagen induced arthritis QTL 213.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1014487011104060283Rat
2316949Gluco60Glucose level QTL 603.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1014487011107057807Rat
61354Pia10Pristane induced arthritis QTL 100.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023444813104060283Rat
631267Cia20Collagen induced arthritis QTL 203.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023444813104060283Rat
61325Aia5Adjuvant induced arthritis QTL 50.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023444813104060283Rat
1331791Cm31Cardiac mass QTL 313.84606heart mass (VT:0007028)heart wet weight (CMO:0000069)1029299504107211142Rat
1576308Schws1Schwannoma susceptibility QTL 10.0041nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)1040035094102359817Rat
631269Cia22Collagen induced arthritis QTL 228.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1040035094104060283Rat
631270Cia23Collagen induced arthritis QTL 233.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1040035094104060283Rat
1298078Stresp5Stress response QTL 52.990.00025blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)1042045676104670812Rat
61387Bp1Blood pressure QTL 15.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1051770177107211142Rat
61387Bp1Blood pressure QTL 15.1arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)1051770177107211142Rat
70171Cari1Carrageenan-induced inflammation QTL 14.90.0005hypodermis integrity trait (VT:0010550)inflammatory exudate volume (CMO:0001429)1053797385107211142Rat
2312662Slep8Serum leptin concentration QTL 80.05blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)1057134272102134272Rat
2312668Scl65Serum cholesterol level QTL 650.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)1057134272102134272Rat
2312672Insul15Insulin level QTL 150.01blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1057134272102134272Rat
1549831Bss6Bone structure and strength QTL 64lumbar vertebra strength trait (VT:0010574)vertebra ultimate force (CMO:0001678)1057576521102576521Rat
2293698Bss43Bone structure and strength QTL 435.330.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra cross-sectional area (CMO:0001689)1059209888104209888Rat
2313103Bss80Bone structure and strength QTL 8020.0001tibia strength trait (VT:1000284)tibia midshaft endosteal cross-sectional area (CMO:0001716)1062057807107057807Rat
2313105Bss79Bone structure and strength QTL 791.80.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)1062057807107057807Rat
61449Ciaa2CIA Autoantibody QTL 27.1blood autoantibody amount (VT:0003725)calculated serum anti-type 2 collagen antibody titer (CMO:0001279)1063221094107211142Rat
2317029Aia19Adjuvant induced arthritis QTL 192.98joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)1066978955107211142Rat
2317039Aia6Adjuvant induced arthritis QTL 64.31joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)1066978955107211142Rat
10450498Bp384Blood pressure QTL 3840.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1067750049107211142Rat
1642980Bp300Blood pressure QTL 300arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1068383129107211142Rat
61396Bp9Blood pressure QTL 94.80.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1068420376107211142Rat
2300172Bmd57Bone mineral density QTL 579.80.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)1069738412107211142Rat
2293646Bss25Bone structure and strength QTL 2510.960.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1069738412107211142Rat
2293663Bss33Bone structure and strength QTL 339.340.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1069738412107211142Rat
6893366Bw106Body weight QTL 1060.30.47body mass (VT:0001259)body weight (CMO:0000012)1070199100107211142Rat
70193Mcs7Mammary carcinoma susceptibility QTL 72.38mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1072224939107211142Rat
2298548Neuinf7Neuroinflammation QTL 73.4nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)1072224939107211142Rat
2292438Bp311Blood pressure QTL 311arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1076246085107211142Rat
1302404Cia27Collagen induced arthritis QTL 272.60.0045joint integrity trait (VT:0010548)experimental arthritis severity measurement (CMO:0001459)1076452683107211142Rat
4889492Pancm2Pancreatic morphology QTL 23.2pancreatic beta cell morphology trait (VT:0005217)ratio of insulin-positive cell area to total area of splenic region of pancreas (CMO:0001814)1076748906107211142Rat
2303589Bw87Body weight QTL 872body mass (VT:0001259)body weight (CMO:0000012)1081285008107211142Rat
2317754Glom25Glomerulus QTL 253.5urine protein amount (VT:0005160)urine protein level (CMO:0000591)1082685200107211142Rat
1600367Mcs15Mammary carcinoma susceptibility QTL 154.5mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1085565469103884409Rat
631538Oia5Oil induced arthritis QTL 5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1087055121107211142Rat
61363Oia3Oil induced arthritis QTL 30.001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1087307617107211142Rat
634320Niddm49Non-insulin dependent diabetes mellitus QTL 494.41blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)1088539139107211142Rat
12880395Cm109Cardiac mass QTL 1090.001heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)1090404397107211142Rat
12880396Am13Aortic mass QTL 130.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)1090404397107211142Rat
12880398Kidm67Kidney mass QTL 670.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)1090404397107211142Rat
12880384Cm107Cardiac mass QTL 1070.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)90404397107211142Rat
12880385Cm108Cardiac mass QTL 1080.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)90404397107211142Rat
1579915Bp280Blood pressure QTL 2800.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1090404397107211142Rat
1300137Bp186Blood pressure QTL 1863.57arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)1090627439107057807Rat
724530Bp149Blood pressure QTL 1490.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1090627439107211142Rat
1558652Bw57Body weight QTL 574.20.0008body mass (VT:0001259)body weight (CMO:0000012)1090910316107211142Rat
61436Cia5Collagen induced arthritis QTL 54.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1091228102104060283Rat
1354641Bvd2Brain ventricular dilatation QTL 26.360.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)1093223816107057807Rat
10450493Bp382Blood pressure QTL 3820.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1094759759107211142Rat
2292436Bp310Blood pressure QTL 310arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1094759759107211142Rat
1576307Cia28Collagen induced arthritis QTL 28joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1096120911104060283Rat
1576313Pia25Pristane induced arthritis QTL 25joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1096120911104060283Rat
1578663Bss18Bone structure and strength QTL 183.6femur width (VT:1000666)femoral neck width (CMO:0001695)1096703043107057807Rat
1578672Bmd16Bone mineral density QTL 166.2femur mineral mass (VT:0010011)cortical volumetric bone mineral density (CMO:0001730)1096703043107057807Rat
631539Oia6Oil induced arthritis QTL 6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1097010147104670812Rat

Markers in Region
Galr2  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.210101,514,753 - 101,514,983 (+)MAPPERmRatBN7.2
Rnor_6.010105,235,266 - 105,235,495NCBIRnor6.0
Rnor_6.010105,156,799 - 105,157,028NCBIRnor6.0
Rnor_5.010104,825,387 - 104,825,616UniSTSRnor5.0
Rnor_5.010104,900,147 - 104,900,376UniSTSRnor5.0
RGSC_v3.410106,394,003 - 106,394,232UniSTSRGSC3.4
Celera10100,087,563 - 100,087,792UniSTS
Cytogenetic Map10q32.3UniSTS
RH131561  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.210101,516,894 - 101,517,074 (+)MAPPERmRatBN7.2
Rnor_6.010105,237,407 - 105,237,586NCBIRnor6.0
Rnor_6.010105,158,940 - 105,159,119NCBIRnor6.0
Rnor_5.010104,827,528 - 104,827,707UniSTSRnor5.0
Rnor_5.010104,902,288 - 104,902,467UniSTSRnor5.0
RGSC_v3.410106,396,144 - 106,396,323UniSTSRGSC3.4
Celera10100,089,704 - 100,089,883UniSTS
Cytogenetic Map10q32.3UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium
Low 3 14 10 30 3 17 9
Below cutoff 25 19 17 9 17 8 11 38 32 19 2 8

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000012523   ⟹   ENSRNOP00000012523
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl10105,156,822 - 105,158,947 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000075548   ⟹   ENSRNOP00000067445
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl10105,235,289 - 105,237,414 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000086288   ⟹   ENSRNOP00000073780
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl10101,514,471 - 101,517,176 (+)Ensembl
Rnor_6.0 Ensembl10105,156,632 - 105,237,611 (+)Ensembl
RefSeq Acc Id: NM_019172   ⟹   NP_062045
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.210101,514,748 - 101,517,176 (+)NCBI
Rnor_6.010105,156,793 - 105,159,221 (+)NCBI
Rnor_5.010104,900,150 - 104,902,315 (+)NCBI
RGSC_v3.410106,394,006 - 106,396,171 (+)RGD
Celera10100,087,566 - 100,089,731 (+)RGD
Sequence:
RefSeq Acc Id: XM_039085710   ⟹   XP_038941638
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.210101,515,008 - 101,517,176 (+)NCBI
RefSeq Acc Id: XM_039085711   ⟹   XP_038941639
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.210101,513,689 - 101,517,176 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_062045   ⟸   NM_019172
- UniProtKB: O08726 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_038941639   ⟸   XM_039085711
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038941638   ⟸   XM_039085710
- Peptide Label: isoform X1
RefSeq Acc Id: ENSRNOP00000073780   ⟸   ENSRNOT00000086288
RefSeq Acc Id: ENSRNOP00000012523   ⟸   ENSRNOT00000012523
RefSeq Acc Id: ENSRNOP00000067445   ⟸   ENSRNOT00000075548

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O08726-F1-model_v2 AlphaFold O08726 1-372 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2657 AgrOrtholog
BioCyc Gene G2FUF-22615 BioCyc
Ensembl Genes ENSRNOG00000061733 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSRNOP00000073780 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000086288 ENTREZGENE, UniProtKB/Swiss-Prot
InterPro GAL2_rcpt UniProtKB/Swiss-Prot
  Galanin_rcpt UniProtKB/Swiss-Prot
  GPCR_Rhodpsn UniProtKB/Swiss-Prot
  GPCR_Rhodpsn_7TM UniProtKB/Swiss-Prot
KEGG Report rno:29234 UniProtKB/Swiss-Prot
NCBI Gene 29234 ENTREZGENE
Pfam 7tm_1 UniProtKB/Swiss-Prot
PhenoGen Galr2 PhenoGen
PRINTS GALANIN2R UniProtKB/Swiss-Prot
  GALANINR UniProtKB/Swiss-Prot
  GPCRRHODOPSN UniProtKB/Swiss-Prot
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/Swiss-Prot
  G_PROTEIN_RECEP_F1_2 UniProtKB/Swiss-Prot
SMART 7TM_GPCR_Srsx UniProtKB/Swiss-Prot
UniProt GALR2_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Galr2  galanin receptor 2  LOC103690156  galanin receptor type 2  Data Merged 737654 PROVISIONAL
2014-08-25 LOC103690156  galanin receptor type 2      Symbol and Name status set to provisional 70820 PROVISIONAL
2002-06-10 Galr2  galanin receptor 2      Symbol and Name status set to approved 70586 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_expression expressed in the brain 69841
gene_expression expressed by POMC (precursor molecule for the opioid peptide beta-endorphin) neurons in the rostral parts of the nucleus 61034
gene_function receptor for neuropeptide galanin 69841
gene_process involved in the control of pituitary functions and feeding behavior and in modulating POMC neuron activity 69841
gene_regulation expression modulated by testosterone 61034