Gene: Itgb4 (integrin subunit beta 4) Rattus norvegicus
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Symbol: Itgb4
Name: integrin subunit beta 4
Description: ENCODES a protein that exhibits G protein-coupled receptor binding (ortholog); insulin-like growth factor I binding (ortholog); neuregulin binding (ortholog); INVOLVED IN amelogenesis (ortholog); autophagy (ortholog); cell adhesion (ortholog); PARTICIPATES IN integrin mediated signaling pathway; arrhythmogenic right ventricular cardiomyopathy pathway; cell-extracellular matrix signaling pathway; ASSOCIATED WITH Abortion, Spontaneous (ortholog); adenoid cystic carcinoma (ortholog); ectodermal dysplasia (ortholog); FOUND IN cell cortex; cytoplasm; membrane; INTERACTS WITH (+)-pilocarpine; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: GP150; integrin beta 4; integrin beta-4; integrin, beta 4
Orthologs:
Homo sapiens (human) : ITGB4 (integrin subunit beta 4)  HGNC  Alliance
Mus musculus (house mouse) : Itgb4 (integrin beta 4)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Itgb4 (integrin subunit beta 4)
Pan paniscus (bonobo/pygmy chimpanzee) : ITGB4 (integrin subunit beta 4)
Canis lupus familiaris (dog) : ITGB4 (integrin subunit beta 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Itgb4 (integrin subunit beta 4)
Sus scrofa (pig) : ITGB4 (integrin subunit beta 4)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.010104,524,000 - 104,560,180 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.010103,725,179 - 103,761,358 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.410106,080,452 - 106,116,632 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.110106,094,955 - 106,131,136 (+)NCBI
Celera1099,781,746 - 99,817,137 (+)NCBICelera
Cytogenetic Map10q32.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model

Annotation    (Toggle Annotation Detail/Summary View)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
  
More on Itgb4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2928
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-01-30
Status: ACTIVE



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