(+)-pilocarpine increases expression EXP 6480464 Pilocarpine results in increased expression of ITGB4 protein CTD PMID:12851778 (-)-epigallocatechin 3-gallate multiple interactions ISO RGD:733257 6480464 [Sulindac co-treated with epigallocatechin gallate] results in decreased expression of ITGB4 mRNA CTD PMID:12628509 (-)-epigallocatechin 3-gallate decreases expression ISO RGD:733257 6480464 epigallocatechin gallate results in decreased expression of ITGB4 protein CTD PMID:31195006 (E)-roxithromycin decreases expression ISO RGD:733257 6480464 Roxithromycin results in decreased expression of ITGB4 protein CTD PMID:14687228 1,2-dimethylhydrazine multiple interactions ISO RGD:733258 6480464 [1, 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ITGB4 mRNA CTD PMID:22206623 1-nitropyrene decreases expression ISO RGD:733257 6480464 1-nitropyrene results in decreased expression of ITGB4 mRNA CTD PMID:19041380 17beta-estradiol multiple interactions ISO RGD:733257 6480464 [Estradiol co-treated with TGFB1 protein] results in increased expression of ITGB4 mRNA more ... CTD PMID:20226447 , PMID:30165855 2,2',4,4',5,5'-hexachlorobiphenyl affects expression ISO RGD:733257 6480464 2 more ... CTD PMID:20638727 2,2',4,4'-Tetrabromodiphenyl ether increases expression ISO RGD:733257 6480464 2 more ... CTD PMID:31675489 2,3',4,4',5-Pentachlorobiphenyl increases expression ISO RGD:733258 6480464 2 more ... CTD PMID:31388691 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of ITGB4 mRNA CTD PMID:22298810 more ... 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of ITGB4 mRNA CTD PMID:33387578 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:733258 6480464 Tetrachlorodibenzodioxin affects the expression of ITGB4 mRNA CTD PMID:21570461 2,3,7,8-Tetrachlorodibenzofuran decreases expression EXP 6480464 2 more ... CTD PMID:32109520 2,4,6-tribromophenol increases expression ISO RGD:733257 6480464 2 more ... CTD PMID:31675489 2-acetamidofluorene increases expression ISO RGD:733258 6480464 2-Acetylaminofluorene results in increased expression of ITGB4 mRNA CTD PMID:17317680 2-hydroxypropanoic acid decreases expression ISO RGD:733257 6480464 Lactic Acid results in decreased expression of ITGB4 mRNA CTD PMID:30851411 3,3',5,5'-tetrabromobisphenol A increases expression ISO RGD:733257 6480464 tetrabromobisphenol A results in increased expression of ITGB4 protein CTD PMID:31675489 4,4'-sulfonyldiphenol multiple interactions ISO RGD:733258 6480464 [bis(4-hydroxyphenyl)sulfone co-treated with Tretinoin] results in decreased expression of ITGB4 mRNA CTD PMID:30951980 4,4'-sulfonyldiphenol affects methylation ISO RGD:733258 6480464 bis(4-hydroxyphenyl)sulfone affects the methylation of ITGB4 exon, bis(4-hydroxyphenyl)sulfone affects the methylation of ITGB4 gene CTD PMID:31683443 , PMID:33297965 5-fluorouracil decreases expression ISO RGD:733257 6480464 Fluorouracil results in decreased expression of ITGB4 mRNA CTD PMID:15205334 6-propyl-2-thiouracil increases expression EXP 6480464 Propylthiouracil results in increased expression of ITGB4 mRNA CTD PMID:24780913 8'-apo-beta,psi-caroten-8'-al decreases expression ISO RGD:733257 6480464 apocarotenal results in decreased expression of ITGB4 mRNA CTD PMID:17034753 acetamide increases expression EXP 6480464 acetamide results in increased expression of ITGB4 mRNA CTD PMID:31881176 acetylsalicylic acid decreases expression ISO RGD:733257 6480464 Aspirin results in decreased expression of ITGB4 mRNA CTD PMID:14976132 acrolein multiple interactions ISO RGD:733257 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of ITGB4 mRNA, [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of ITGB4 mRNA CTD PMID:32699268 all-trans-retinoic acid multiple interactions ISO RGD:733258 6480464 [bis(4-hydroxyphenyl)sulfone co-treated with Tretinoin] results in decreased expression of ITGB4 mRNA more ... CTD PMID:10748128 , PMID:30951980 all-trans-retinoic acid decreases expression ISO RGD:733258 6480464 Tretinoin results in decreased expression of ITGB4 mRNA CTD PMID:10748128 alpha-pinene multiple interactions ISO RGD:733257 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of ITGB4 mRNA, [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of ITGB4 mRNA CTD PMID:32699268 aristolochic acids increases expression EXP 6480464 Aristolochic Acids results in increased expression of ITGB4 mRNA CTD PMID:19717638 arsenous acid decreases response to substance ISO RGD:733257 6480464 ITGB4 protein results in decreased susceptibility to Arsenic Trioxide CTD PMID:20707922 benzo[a]pyrene multiple interactions ISO RGD:733258 6480464 Benzo(a)pyrene promotes the reaction [AHR protein binds to ITGB4 promoter] CTD PMID:19654925 benzo[a]pyrene increases expression ISO RGD:733257 6480464 Benzo(a)pyrene results in increased expression of ITGB4 mRNA CTD PMID:32234424 benzo[a]pyrene decreases methylation ISO RGD:733257 6480464 Benzo(a)pyrene results in decreased methylation of ITGB4 5' UTR CTD PMID:27901495 benzo[a]pyrene affects methylation ISO RGD:733257 6480464 Benzo(a)pyrene affects the methylation of ITGB4 promoter CTD PMID:27901495 benzo[a]pyrene decreases expression ISO RGD:733257 6480464 Benzo(a)pyrene results in decreased expression of ITGB4 protein CTD PMID:32717239 benzo[b]fluoranthene increases expression ISO RGD:733258 6480464 benzo(b)fluoranthene results in increased expression of ITGB4 mRNA CTD PMID:26377693 berberine increases expression ISO RGD:733257 152995489 berberine increases expression of ITGB4 protein in colon epithelial cells RGD beta-carotene decreases expression ISO RGD:733257 6480464 beta Carotene results in decreased expression of ITGB4 mRNA CTD PMID:17034753 bis(2-chloroethyl) sulfide multiple interactions ISO RGD:733257 6480464 Mustard Gas affects the expression of [ITGA6 protein binds to ITGB4 protein] CTD PMID:12880345 bis(2-chloroethyl) sulfide decreases expression ISO RGD:733257 6480464 Mustard Gas results in decreased expression of ITGB4 protein CTD PMID:11428621 , PMID:12880345 bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of ITGB4 mRNA CTD PMID:25181051 bisphenol A decreases expression ISO RGD:733257 6480464 bisphenol A results in decreased expression of ITGB4 protein CTD PMID:31675489 bisphenol A increases expression ISO RGD:733258 6480464 bisphenol A results in increased expression of ITGB4 mRNA CTD PMID:32156529 , PMID:34585602 bisphenol A increases expression ISO RGD:733257 6480464 bisphenol A results in increased expression of ITGB4 mRNA CTD PMID:31715268 bisphenol A multiple interactions ISO RGD:733258 6480464 [bisphenol A co-treated with Tretinoin] results in decreased expression of ITGB4 mRNA CTD PMID:30951980 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of ITGB4 mRNA CTD PMID:30816183 , PMID:33296240 bisphenol A decreases methylation ISO RGD:733258 6480464 bisphenol A results in decreased methylation of ITGB4 promoter CTD PMID:27312807 bisphenol F increases expression ISO RGD:733258 6480464 bisphenol F results in increased expression of ITGB4 mRNA CTD PMID:30951980 bisphenol F multiple interactions ISO RGD:733258 6480464 [bisphenol F co-treated with Tretinoin] results in decreased expression of ITGB4 mRNA CTD PMID:30951980 butan-1-ol multiple interactions ISO RGD:733257 6480464 [[Gasoline co-treated with 1-Butanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in increased expression of ITGB4 mRNA CTD PMID:29432896 butane-2,3-dione decreases expression ISO RGD:733257 6480464 Diacetyl results in decreased expression of ITGB4 protein CTD PMID:34031698 cadmium atom increases expression ISO RGD:733258 6480464 Cadmium results in increased expression of ITGB4 mRNA CTD PMID:23358150 cadmium atom multiple interactions ISO RGD:733257 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of ITGB4 mRNA CTD PMID:35301059 cadmium dichloride multiple interactions ISO RGD:733257 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of ITGB4 mRNA, [sodium arsenite co-treated with Cadmium Chloride co-treated with chromic oxide co-treated with chromous chloride co-treated with lead acetate] results in increased expression of ITGB4 mRNA CTD PMID:12634122 , PMID:35301059 cadmium nitrate decreases expression ISO RGD:733257 6480464 cadmium nitrate results in decreased expression of ITGB4 protein CTD PMID:19061949 caffeine affects phosphorylation ISO RGD:733257 6480464 Caffeine affects the phosphorylation of ITGB4 protein CTD PMID:35688186 calcitriol increases expression ISO RGD:733257 6480464 Calcitriol results in increased expression of ITGB4 mRNA CTD PMID:26485663 chloropicrin decreases expression ISO RGD:733257 6480464 chloropicrin results in decreased expression of ITGB4 mRNA CTD PMID:26352163 , PMID:28476498 chloroprene increases expression ISO RGD:733258 6480464 Chloroprene results in increased expression of ITGB4 mRNA CTD PMID:23125180 choline multiple interactions ISO RGD:733258 6480464 [Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc] results in decreased expression of ITGB4 mRNA more ... CTD PMID:20938992 , PMID:33549593 chromium(6+) decreases expression ISO RGD:733257 6480464 chromium hexavalent ion results in decreased expression of ITGB4 mRNA CTD PMID:30690063 cisplatin increases expression ISO RGD:733257 6480464 Cisplatin results in increased expression of ITGB4 mRNA CTD PMID:12066199 cisplatin multiple interactions ISO RGD:733257 6480464 [Cisplatin co-treated with jinfukang] results in increased expression of ITGB4 mRNA CTD PMID:27392435 clarithromycin decreases expression ISO RGD:733257 6480464 Clarithromycin results in decreased expression of ITGB4 protein CTD PMID:14687228 copper atom multiple interactions ISO RGD:733257 6480464 [Chelating Agents binds to Copper] which results in increased expression of ITGB4 mRNA CTD PMID:30911355 copper(0) multiple interactions ISO RGD:733257 6480464 [Chelating Agents binds to Copper] which results in increased expression of ITGB4 mRNA CTD PMID:30911355 cyanocob(III)alamin multiple interactions ISO RGD:733258 6480464 [Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc] results in decreased expression of ITGB4 mRNA CTD PMID:33549593 cyclosporin A increases expression ISO RGD:733257 6480464 Cyclosporine results in increased expression of ITGB4 mRNA CTD PMID:22147139 decabromodiphenyl ether increases expression ISO RGD:733257 6480464 decabromobiphenyl ether results in increased expression of ITGB4 protein CTD PMID:31675489 diallyl trisulfide decreases expression ISO RGD:733257 6480464 diallyl trisulfide results in decreased expression of ITGB4 protein CTD PMID:28741790 diarsenic trioxide decreases response to substance ISO RGD:733257 6480464 ITGB4 protein results in decreased susceptibility to Arsenic Trioxide CTD PMID:20707922 dibenz[a,h]anthracene increases expression ISO RGD:733258 6480464 1 more ... CTD PMID:26377693 dichromium trioxide multiple interactions ISO RGD:733257 6480464 [sodium arsenite co-treated with Cadmium Chloride co-treated with chromic oxide co-treated with chromous chloride co-treated with lead acetate] results in increased expression of ITGB4 mRNA CTD PMID:12634122 doxorubicin decreases expression ISO RGD:733257 6480464 Doxorubicin results in decreased expression of ITGB4 mRNA CTD PMID:15205334 , PMID:29803840 doxorubicin increases oxidation EXP 6480464 Doxorubicin results in increased oxidation of ITGB4 protein CTD PMID:28818578 endosulfan decreases expression EXP 6480464 Endosulfan results in decreased expression of ITGB4 mRNA CTD PMID:29391264 ethanol multiple interactions ISO RGD:733257 6480464 [[Gasoline co-treated with Ethanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in increased expression of ITGB4 mRNA CTD PMID:29432896 fipronil decreases expression EXP 6480464 fipronil results in decreased expression of ITGB4 mRNA CTD PMID:23962444 folic acid multiple interactions ISO RGD:733258 6480464 [1 more ... CTD PMID:20938992 more ... furan increases expression EXP 6480464 furan results in increased expression of ITGB4 mRNA CTD PMID:27387713 gentamycin decreases expression EXP 6480464 Gentamicins results in decreased expression of ITGB4 mRNA CTD PMID:33387578 glycidol increases expression EXP 6480464 glycidol results in increased expression of ITGB4 mRNA CTD PMID:24395379 glycine betaine multiple interactions ISO RGD:733258 6480464 [Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc] results in decreased expression of ITGB4 mRNA CTD PMID:33549593 hydrogen peroxide decreases expression ISO RGD:733257 6480464 Hydrogen Peroxide results in decreased expression of ITGB4 mRNA CTD PMID:12419474 inulin multiple interactions ISO RGD:733258 6480464 [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of ITGB4 mRNA CTD PMID:36331819 isobutanol multiple interactions ISO RGD:733257 6480464 [[Gasoline co-treated with isobutyl alcohol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in increased expression of ITGB4 mRNA CTD PMID:29432896 ivermectin decreases expression ISO RGD:733257 6480464 Ivermectin results in decreased expression of ITGB4 protein CTD PMID:32959892 L-methionine multiple interactions ISO RGD:733258 6480464 [Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc] results in decreased expression of ITGB4 mRNA more ... CTD PMID:20938992 , PMID:33549593 lead diacetate multiple interactions ISO RGD:733257 6480464 [sodium arsenite co-treated with Cadmium Chloride co-treated with chromic oxide co-treated with chromous chloride co-treated with lead acetate] results in increased expression of ITGB4 mRNA CTD PMID:12634122 lead(0) affects expression ISO RGD:733257 6480464 Lead affects the expression of ITGB4 mRNA CTD PMID:28903495 lead(2+) affects expression ISO RGD:733257 6480464 Lead affects the expression of ITGB4 mRNA CTD PMID:28903495 lipopolysaccharide multiple interactions ISO RGD:733257 6480464 [NAT10 protein affects the susceptibility to Lipopolysaccharides] which affects the expression of ITGB4 mRNA CTD PMID:35877022 methotrexate increases expression ISO RGD:733257 6480464 Methotrexate results in increased expression of ITGB4 mRNA CTD PMID:21678067 methylseleninic acid decreases expression ISO RGD:733257 6480464 methylselenic acid results in decreased expression of ITGB4 mRNA CTD PMID:12517777 ML-7 multiple interactions ISO RGD:733257 6480464 ML 7 affects the localization of [ITGA6 protein binds to ITGB4 protein] CTD PMID:14691950 mono(2-ethylhexyl) phthalate decreases expression ISO RGD:733258 6480464 mono-(2-ethylhexyl)phthalate results in decreased expression of ITGB4 mRNA CTD PMID:22401849 N-methyl-N'-nitro-N-nitrosoguanidine decreases expression ISO RGD:733257 6480464 Methylnitronitrosoguanidine results in decreased expression of ITGB4 mRNA CTD PMID:12634122 , PMID:12773770 nickel subsulfide decreases expression ISO RGD:733257 6480464 nickel subsulfide results in decreased expression of ITGB4 mRNA CTD PMID:12760830 nickel sulfate increases expression ISO RGD:733257 6480464 nickel sulfate results in increased expression of ITGB4 mRNA CTD PMID:18651567 , PMID:22714537 nitrofen decreases expression EXP 6480464 nitrofen results in decreased expression of ITGB4 mRNA CTD PMID:33484710 ochratoxin A increases expression EXP 6480464 ochratoxin A results in increased expression of ITGB4 mRNA CTD PMID:19717638 ofloxacin decreases expression ISO RGD:733257 6480464 Ofloxacin results in decreased expression of ITGB4 protein CTD PMID:14687228 omega-6 fatty acid increases expression ISO RGD:733257 6480464 Fatty Acids, Omega-6 results in increased expression of ITGB4 mRNA CTD PMID:16823509 ozone multiple interactions ISO RGD:733257 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of ITGB4 mRNA more ... CTD PMID:32699268 paracetamol decreases expression EXP 6480464 Acetaminophen results in decreased expression of ITGB4 mRNA CTD PMID:33387578 perfluorooctane-1-sulfonic acid multiple interactions ISO RGD:733258 6480464 [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of ITGB4 mRNA CTD PMID:36331819 potassium chromate decreases expression ISO RGD:733257 6480464 potassium chromate(VI) results in decreased expression of ITGB4 mRNA CTD PMID:22714537 potassium dichromate decreases expression ISO RGD:733258 6480464 Potassium Dichromate results in decreased expression of ITGB4 mRNA CTD PMID:23608068 progesterone multiple interactions ISO RGD:733257 6480464 [Progesterone affects the activity of PGR protein alternative form] which affects the expression of ITGB4 mRNA more ... CTD PMID:15866122 , PMID:20226447 progesterone increases expression ISO RGD:733257 6480464 Progesterone results in increased expression of ITGB4 mRNA CTD PMID:20226447 propanal increases expression ISO RGD:733257 6480464 propionaldehyde results in increased expression of ITGB4 mRNA CTD PMID:26079696 rac-lactic acid decreases expression ISO RGD:733257 6480464 Lactic Acid results in decreased expression of ITGB4 mRNA CTD PMID:30851411 simvastatin affects expression ISO RGD:733257 6480464 Simvastatin affects the expression of ITGB4 mRNA, Simvastatin affects the expression of ITGB4 protein CTD PMID:19110722 simvastatin increases expression ISO RGD:733257 6480464 Simvastatin results in increased expression of ITGB4 mRNA, Simvastatin results in increased expression of ITGB4 protein CTD PMID:14630613 sodium arsenite multiple interactions ISO RGD:733257 6480464 [sodium arsenite co-treated with Cadmium Chloride co-treated with chromic oxide co-treated with chromous chloride co-treated with lead acetate] results in increased expression of ITGB4 mRNA more ... CTD PMID:12634122 more ... sodium arsenite increases expression ISO RGD:733257 6480464 sodium arsenite results in increased expression of ITGB4 mRNA CTD PMID:29301061 sodium arsenite decreases expression ISO RGD:733257 6480464 sodium arsenite results in decreased expression of ITGB4 mRNA CTD PMID:12377979 sodium dichromate decreases expression ISO RGD:733257 6480464 sodium bichromate results in decreased expression of ITGB4 mRNA CTD PMID:12760830 sotorasib multiple interactions ISO RGD:733257 6480464 [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ITGB4 mRNA CTD PMID:36139627 sulindac multiple interactions ISO RGD:733257 6480464 [Sulindac co-treated with epigallocatechin gallate] results in decreased expression of ITGB4 mRNA CTD PMID:12628509 tert-butyl hydroperoxide decreases expression ISO RGD:733257 6480464 tert-Butylhydroperoxide results in decreased expression of ITGB4 mRNA CTD PMID:12419474 , PMID:15336504 testosterone decreases expression ISO RGD:733257 6480464 Testosterone results in decreased expression of ITGB4 mRNA CTD PMID:33359661 tetrachloromethane affects expression EXP 6480464 Carbon Tetrachloride affects the expression of ITGB4 mRNA CTD PMID:12734012 tetrathiomolybdate(2-) decreases expression ISO RGD:733257 6480464 tetrathiomolybdate analog results in decreased expression of ITGB4 mRNA CTD PMID:19323979 thioacetamide increases expression EXP 6480464 Thioacetamide results in increased expression of ITGB4 mRNA CTD PMID:23411599 titanium dioxide decreases expression ISO RGD:733258 6480464 titanium dioxide results in decreased expression of ITGB4 mRNA CTD PMID:23557971 trametinib multiple interactions ISO RGD:733257 6480464 [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ITGB4 mRNA CTD PMID:36139627 tributylstannane increases expression ISO RGD:733258 6480464 tributyltin results in increased expression of ITGB4 mRNA CTD PMID:31939706 trichloroethene increases expression EXP 6480464 Trichloroethylene results in increased expression of ITGB4 mRNA CTD PMID:33387578 triptonide increases expression ISO RGD:733258 6480464 triptonide results in increased expression of ITGB4 mRNA CTD PMID:33045310 valproic acid increases methylation ISO RGD:733257 6480464 Valproic Acid results in increased methylation of ITGB4 gene CTD PMID:29154799 valproic acid increases expression EXP 6480464 Valproic Acid results in increased expression of ITGB4 mRNA CTD PMID:29427782 vinclozolin decreases expression EXP 6480464 vinclozolin results in decreased expression of ITGB4 mRNA CTD PMID:23034163 vorinostat increases expression EXP 6480464 vorinostat results in increased expression of ITGB4 mRNA CTD PMID:20060208 Y-27632 multiple interactions ISO RGD:733257 6480464 Y 27632 affects the localization of [ITGA6 protein binds to ITGB4 protein] CTD PMID:14691950 zinc atom multiple interactions ISO RGD:733258 6480464 [Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc] results in decreased expression of ITGB4 mRNA CTD PMID:33549593 zinc(0) multiple interactions ISO RGD:733258 6480464 [Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc] results in decreased expression of ITGB4 mRNA CTD PMID:33549593