Mafg (MAF bZIP transcription factor G) - Rat Genome Database

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Gene: Mafg (MAF bZIP transcription factor G) Rattus norvegicus
Analyze
Symbol: Mafg
Name: MAF bZIP transcription factor G
RGD ID: 619953
Description: Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and identical protein binding activity. Involved in regulation of cellular pH. Predicted to be part of RNA polymerase II transcription regulator complex. Predicted to be active in nucleus. Orthologous to human MAFG (MAF bZIP transcription factor G); PARTICIPATES IN nuclear factor, erythroid 2 like 2 signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: transcription factor MafG; v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G; v-maf musculoaponeurotic fibrosarcoma (avian) oncogene family, protein G; v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G; v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian); v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr810106,401,633 - 106,410,159 (-)NCBIGRCr8
mRatBN7.210105,903,307 - 105,911,808 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl10105,903,237 - 105,912,026 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx10111,007,074 - 111,015,576 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.010110,470,111 - 110,478,613 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.010105,823,759 - 105,832,258 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.010109,802,877 - 109,811,476 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl10109,806,159 - 109,811,323 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.010109,395,929 - 109,404,465 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.410110,019,741 - 110,024,927 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.110110,034,252 - 110,039,431 (-)NCBI
Celera10104,449,965 - 104,455,151 (-)NCBICelera
Cytogenetic Map10q32.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
(E)-cinnamyl alcohol  (ISO)
1,2-dimethylhydrazine  (ISO)
1-chloro-2,4-dinitrobenzene  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,6-dinitrotoluene  (EXP)
2-hydroxypropanoic acid  (ISO)
2-tert-butylhydroquinone  (ISO)
3,4-methylenedioxymethamphetamine  (EXP)
4-amino-2,6-dinitrotoluene  (EXP)
4-hydroxynon-2-enal  (ISO)
acrolein  (ISO)
acrylamide  (ISO)
all-trans-retinoic acid  (ISO)
alpha-hexylcinnamaldehyde  (ISO)
alpha-pinene  (ISO)
amiodarone  (ISO)
ammonium chloride  (EXP)
andrographolide  (ISO)
aristolochic acid A  (ISO)
arotinoid acid  (ISO)
azoxystrobin  (ISO)
Bandrowski's base  (ISO)
Bardoxolone methyl  (ISO)
benzene  (ISO)
benzo[a]pyrene  (ISO)
benzoic acid  (ISO)
beta-naphthoflavone  (ISO)
bisphenol A  (EXP,ISO)
bortezomib  (ISO)
butan-1-ol  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
cadmium sulfate  (ISO)
cannabidiol  (ISO)
CGP 52608  (ISO)
chenodeoxycholic acid  (ISO)
CHIR 99021  (ISO)
chloroacetaldehyde  (ISO)
chloroprene  (ISO)
chlorpyrifos  (ISO)
cinnamyl alcohol  (ISO)
cisplatin  (ISO)
clodronic acid  (ISO)
clofibrate  (ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) chloride  (ISO)
copper(II) sulfate  (ISO)
cortisol  (ISO)
CU-O LINKAGE  (ISO)
cyclosporin A  (EXP,ISO)
DDE  (ISO)
deoxycholic acid  (ISO)
dibutyl phthalate  (ISO)
dicrotophos  (ISO)
diethyl malate  (ISO)
diethyl maleate  (ISO)
dioxygen  (ISO)
disodium selenite  (ISO)
disulfiram  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
eugenol  (ISO)
fenofibrate  (EXP,ISO)
fenthion  (ISO)
flutamide  (EXP)
folic acid  (ISO)
gentamycin  (EXP)
geraniol  (ISO)
glycochenodeoxycholic acid  (ISO)
glycocholic acid  (ISO)
glycodeoxycholic acid  (ISO)
hexane  (ISO)
hydrogen peroxide  (ISO)
hypochlorous acid  (ISO)
ibuprofen  (EXP)
ifosfamide  (ISO)
iron dichloride  (ISO)
isoeugenol  (ISO)
L-ascorbic acid  (ISO)
L-ascorbic acid 2-phosphate  (ISO)
lead diacetate  (ISO)
lead(0)  (ISO)
leflunomide  (ISO)
lithocholic acid  (ISO)
menadione  (ISO)
mercury dibromide  (ISO)
metformin  (EXP)
methidathion  (ISO)
methyl methanesulfonate  (ISO)
methyl salicylate  (ISO)
methylmercury chloride  (ISO)
methylparaben  (ISO)
nefazodone  (ISO)
nickel sulfate  (ISO)
ochratoxin A  (ISO)
organoselenium compound  (ISO)
ozone  (ISO)
p-chloromercuribenzoic acid  (ISO)
paracetamol  (EXP)
paraquat  (ISO)
pentachlorophenol  (ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
phlorizin  (ISO)
phorone  (EXP)
picoxystrobin  (ISO)
potassium chromate  (ISO)
propan-2-ol  (ISO)
propiconazole  (ISO)
quercetin  (ISO)
rac-lactic acid  (ISO)
reactive oxygen species  (ISO)
rotenone  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
S-adenosyl-L-methioninate  (ISO)
S-adenosyl-L-methionine  (ISO)
SB 431542  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (ISO)
sodium dodecyl sulfate  (ISO)
sulforaphane  (ISO)
sunitinib  (ISO)
tert-butyl hydroperoxide  (ISO)
thiram  (ISO)
titanium dioxide  (ISO)
trans-isoeugenol  (ISO)
Tributyltin oxide  (ISO)
trichloroethene  (EXP)
triclosan  (ISO)
troglitazone  (EXP)
tunicamycin  (ISO)
urethane  (ISO)
ursodeoxycholic acid  (ISO)
valproic acid  (ISO)
XAV939  (ISO)
zinc atom  (ISO)
zinc dichloride  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. The Nrf2 regulatory network provides an interface between redox and intermediary metabolism. Hayes JD and Dinkova-Kostova AT, Trends Biochem Sci. 2014 Apr;39(4):199-218. doi: 10.1016/j.tibs.2014.02.002. Epub 2014 Mar 16.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. GOA pipeline RGD automated data pipeline
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. MafG-2 is a novel Maf protein that is expressed by stimulation of extracellular H(+). Shimokawa N, etal., Cell Signal 2001 Nov;13(11):835-9.
8. Cloning of MafG homologue from the rat brain by differential display and its expression after hypercapnic stimulation. Shimokawa N, etal., Mol Cell Biochem 2000 Jan;203(1-2):135-41.
9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:9679061   PMID:12220541   PMID:14517290   PMID:14978030   PMID:15087497   PMID:15574414   PMID:15828020   PMID:17928287  


Genomics

Comparative Map Data
Mafg
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr810106,401,633 - 106,410,159 (-)NCBIGRCr8
mRatBN7.210105,903,307 - 105,911,808 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl10105,903,237 - 105,912,026 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx10111,007,074 - 111,015,576 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.010110,470,111 - 110,478,613 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.010105,823,759 - 105,832,258 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.010109,802,877 - 109,811,476 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl10109,806,159 - 109,811,323 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.010109,395,929 - 109,404,465 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.410110,019,741 - 110,024,927 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.110110,034,252 - 110,039,431 (-)NCBI
Celera10104,449,965 - 104,455,151 (-)NCBICelera
Cytogenetic Map10q32.3NCBI
MAFG
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381781,918,270 - 81,931,244 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1781,918,270 - 81,927,735 (-)EnsemblGRCh38hg38GRCh38
GRCh371779,876,146 - 79,885,611 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361777,469,438 - 77,478,879 (-)NCBINCBI36Build 36hg18NCBI36
Celera1776,480,214 - 76,489,629 (-)NCBICelera
Cytogenetic Map17q25.3NCBI
HuRef1775,277,766 - 75,297,553 (-)NCBIHuRef
CHM1_11779,962,349 - 79,971,791 (-)NCBICHM1_1
T2T-CHM13v2.01782,785,430 - 82,798,403 (-)NCBIT2T-CHM13v2.0
Mafg
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911120,515,943 - 120,525,771 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl11120,515,943 - 120,524,426 (-)EnsemblGRCm39 Ensembl
GRCm3811120,625,117 - 120,634,955 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11120,625,117 - 120,633,600 (-)EnsemblGRCm38mm10GRCm38
MGSCv3711120,489,662 - 120,494,861 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3611120,444,438 - 120,449,637 (-)NCBIMGSCv36mm8
Celera11132,363,642 - 132,365,175 (-)NCBICelera
Cytogenetic Map11E2NCBI
cM Map1184.35NCBI
Mafg
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555061,247,293 - 1,252,167 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555061,247,294 - 1,252,167 (+)NCBIChiLan1.0ChiLan1.0
MAFG
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21998,454,393 - 98,463,741 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan117103,355,168 - 103,364,469 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01776,323,874 - 76,333,300 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11782,026,365 - 82,035,036 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1782,030,699 - 82,031,278 (-)Ensemblpanpan1.1panPan2
MAFG
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.19368,102 - 373,825 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl9372,216 - 372,797 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha9970,324 - 975,925 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.09961,543 - 967,144 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl9965,535 - 966,116 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.19986,697 - 992,297 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.091,113,317 - 1,118,910 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.091,191,956 - 1,200,828 (+)NCBIUU_Cfam_GSD_1.0
Mafg
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602978,486 - 986,842 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365945,424,940 - 5,430,097 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365945,425,117 - 5,430,057 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MAFG
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl121,071,632 - 1,074,688 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1121,069,074 - 1,078,081 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
MAFG
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11673,793,362 - 73,801,185 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1673,796,453 - 73,797,034 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607745,244,171 - 45,253,347 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mafg
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462480110,764,186 - 10,769,454 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462480110,760,599 - 10,769,578 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Mafg
20 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:591
Count of miRNA genes:288
Interacting mature miRNAs:364
Transcripts:ENSRNOT00000054970
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
12880384Cm107Cardiac mass QTL 1070.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)90404397107211142Rat
12880385Cm108Cardiac mass QTL 1080.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)90404397107211142Rat
1354641Bvd2Brain ventricular dilatation QTL 26.360.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)1093223816107057807Rat
2317029Aia19Adjuvant induced arthritis QTL 192.98joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)1066978955107211142Rat
2303589Bw87Body weight QTL 872body mass (VT:0001259)body weight (CMO:0000012)1081285008107211142Rat
12880396Am13Aortic mass QTL 130.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)1090404397107211142Rat
61449Ciaa2CIA Autoantibody QTL 27.1blood autoantibody amount (VT:0003725)calculated serum anti-type 2 collagen antibody titer (CMO:0001279)1063221094107211142Rat
12880398Kidm67Kidney mass QTL 670.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)1090404397107211142Rat
61387Bp1Blood pressure QTL 15.1arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)1051770177107211142Rat
2317039Aia6Adjuvant induced arthritis QTL 64.31joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)1066978955107211142Rat
12880395Cm109Cardiac mass QTL 1090.001heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)1090404397107211142Rat
1579915Bp280Blood pressure QTL 2800.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1090404397107211142Rat
61396Bp9Blood pressure QTL 94.80.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1068420376107211142Rat
2298548Neuinf7Neuroinflammation QTL 73.4nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)1072224939107211142Rat
1302404Cia27Collagen induced arthritis QTL 272.60.0045joint integrity trait (VT:0010548)experimental arthritis severity measurement (CMO:0001459)1076452683107211142Rat
2317754Glom25Glomerulus QTL 253.5urine protein amount (VT:0005160)urine protein level (CMO:0000591)1082685200107211142Rat
634320Niddm49Non-insulin dependent diabetes mellitus QTL 494.41blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)1088539139107211142Rat
70171Cari1Carrageenan-induced inflammation QTL 14.90.0005hypodermis integrity trait (VT:0010550)inflammatory exudate volume (CMO:0001429)1053797385107211142Rat
1331791Cm31Cardiac mass QTL 313.84606heart mass (VT:0007028)heart wet weight (CMO:0000069)1029299504107211142Rat
10450498Bp384Blood pressure QTL 3840.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1067750049107211142Rat
4889492Pancm2Pancreatic morphology QTL 23.2pancreatic beta cell morphology trait (VT:0005217)ratio of insulin-positive cell area to total area of splenic region of pancreas (CMO:0001814)1076748906107211142Rat
6893366Bw106Body weight QTL 1060.30.47body mass (VT:0001259)body weight (CMO:0000012)1070199100107211142Rat
10450493Bp382Blood pressure QTL 3820.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1094759759107211142Rat
1578672Bmd16Bone mineral density QTL 166.2femur mineral mass (VT:0010011)compact volumetric bone mineral density (CMO:0001730)1096703043107057807Rat
2313103Bss80Bone structure and strength QTL 8020.0001tibia strength trait (VT:1000284)tibia midshaft endosteal cross-sectional area (CMO:0001716)1062057807107057807Rat
2293646Bss25Bone structure and strength QTL 2510.960.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1069738412107211142Rat
2300172Bmd57Bone mineral density QTL 579.80.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)1069738412107211142Rat
70193Mcs7Mammary carcinoma susceptibility QTL 72.38mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1072224939107211142Rat
2313105Bss79Bone structure and strength QTL 791.80.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)1062057807107057807Rat
61363Oia3Oil induced arthritis QTL 30.001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1087307617107211142Rat
2292438Bp311Blood pressure QTL 311arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1076246085107211142Rat
2316949Gluco60Glucose level QTL 603.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1014487011107057807Rat
2292436Bp310Blood pressure QTL 310arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1094759759107211142Rat
724530Bp149Blood pressure QTL 1490.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1090627439107211142Rat
1300137Bp186Blood pressure QTL 1863.57arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)1090627439107057807Rat
631538Oia5Oil induced arthritis QTL 5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1087055121107211142Rat
1642980Bp300Blood pressure QTL 300arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1068383129107211142Rat
2293663Bss33Bone structure and strength QTL 339.340.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1069738412107211142Rat
1578663Bss18Bone structure and strength QTL 183.6femur width (VT:1000666)femoral neck width (CMO:0001695)1096703043107057807Rat

Markers in Region
Mafg  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.210105,907,895 - 105,908,072 (+)MAPPERmRatBN7.2
Rnor_6.010109,807,464 - 109,807,640NCBIRnor6.0
Rnor_5.010109,400,516 - 109,400,692UniSTSRnor5.0
RGSC_v3.410110,021,068 - 110,021,244UniSTSRGSC3.4
Celera10104,451,292 - 104,451,468UniSTS
Cytogenetic Map10q32.3UniSTS
Mafg  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.210105,906,636 - 105,907,531 (+)MAPPERmRatBN7.2
Rnor_6.010109,806,205 - 109,807,099NCBIRnor6.0
Rnor_5.010109,399,257 - 109,400,151UniSTSRnor5.0
Celera10104,450,033 - 104,450,927UniSTS
Cytogenetic Map10q32.3UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_022386 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006247912 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006247913 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006247921 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006247922 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008768482 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017597521 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039086787 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039086788 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063269807 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063269808 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063269809 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063269810 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063269811 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB026487 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB050011 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC131537 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC078828 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473948 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ212343 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000054970   ⟹   ENSRNOP00000051853
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl10105,906,591 - 105,912,026 (-)Ensembl
Rnor_6.0 Ensembl10109,806,159 - 109,811,323 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000104193   ⟹   ENSRNOP00000091294
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl10105,903,237 - 105,911,010 (-)Ensembl
RefSeq Acc Id: NM_022386   ⟹   NP_071781
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr810106,401,633 - 106,410,132 (-)NCBI
mRatBN7.210105,903,307 - 105,911,808 (-)NCBI
Rnor_6.010109,806,137 - 109,811,323 (-)NCBI
Rnor_5.010109,395,929 - 109,404,465 (-)NCBI
RGSC_v3.410110,019,741 - 110,024,927 (-)RGD
Celera10104,449,965 - 104,455,151 (-)RGD
Sequence:
RefSeq Acc Id: XM_006247913   ⟹   XP_006247975
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr810106,401,633 - 106,409,912 (-)NCBI
mRatBN7.210105,903,307 - 105,911,588 (-)NCBI
Rnor_6.010109,802,877 - 109,811,156 (-)NCBI
Rnor_5.010109,395,929 - 109,404,465 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006247921   ⟹   XP_006247983
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr810106,401,633 - 106,409,912 (-)NCBI
mRatBN7.210105,903,307 - 105,911,588 (-)NCBI
Rnor_6.010109,802,877 - 109,811,156 (-)NCBI
Rnor_5.010109,395,929 - 109,404,465 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006247922   ⟹   XP_006247984
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr810106,401,633 - 106,409,912 (-)NCBI
mRatBN7.210105,903,307 - 105,911,588 (-)NCBI
Rnor_6.010109,802,877 - 109,811,156 (-)NCBI
Rnor_5.010109,395,929 - 109,404,465 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008768482   ⟹   XP_008766704
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr810106,401,633 - 106,407,008 (-)NCBI
mRatBN7.210105,903,307 - 105,908,680 (-)NCBI
Rnor_6.010109,802,877 - 109,811,156 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039086787   ⟹   XP_038942715
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr810106,401,633 - 106,409,912 (-)NCBI
mRatBN7.210105,903,307 - 105,911,588 (-)NCBI
RefSeq Acc Id: XM_039086788   ⟹   XP_038942716
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr810106,401,633 - 106,409,912 (-)NCBI
mRatBN7.210105,903,307 - 105,911,588 (-)NCBI
RefSeq Acc Id: XM_063269807   ⟹   XP_063125877
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr810106,401,633 - 106,409,912 (-)NCBI
RefSeq Acc Id: XM_063269808   ⟹   XP_063125878
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr810106,401,633 - 106,410,159 (-)NCBI
RefSeq Acc Id: XM_063269809   ⟹   XP_063125879
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr810106,401,633 - 106,409,912 (-)NCBI
RefSeq Acc Id: XM_063269810   ⟹   XP_063125880
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr810106,401,633 - 106,409,912 (-)NCBI
RefSeq Acc Id: XM_063269811   ⟹   XP_063125881
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr810106,401,633 - 106,410,152 (-)NCBI
RefSeq Acc Id: NP_071781   ⟸   NM_022386
- Sequence:
RefSeq Acc Id: XP_006247983   ⟸   XM_006247921
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_006247975   ⟸   XM_006247913
- Peptide Label: isoform X1
- UniProtKB: A0A8L2QQP9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006247984   ⟸   XM_006247922
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_008766704   ⟸   XM_008768482
- Peptide Label: isoform X3
- Sequence:
Ensembl Acc Id: ENSRNOP00000051853   ⟸   ENSRNOT00000054970
RefSeq Acc Id: XP_038942716   ⟸   XM_039086788
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038942715   ⟸   XM_039086787
- Peptide Label: isoform X3
Ensembl Acc Id: ENSRNOP00000091294   ⟸   ENSRNOT00000104193
RefSeq Acc Id: XP_063125878   ⟸   XM_063269808
- Peptide Label: isoform X2
- UniProtKB: Q99N83 (UniProtKB/Swiss-Prot),   Q76MX4 (UniProtKB/Swiss-Prot),   A6HLH1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063125881   ⟸   XM_063269811
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063125880   ⟸   XM_063269810
- Peptide Label: isoform X2
- UniProtKB: Q99N83 (UniProtKB/Swiss-Prot),   Q76MX4 (UniProtKB/Swiss-Prot),   A6HLH1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063125879   ⟸   XM_063269809
- Peptide Label: isoform X2
- UniProtKB: Q99N83 (UniProtKB/Swiss-Prot),   Q76MX4 (UniProtKB/Swiss-Prot),   A6HLH1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063125877   ⟸   XM_063269807
- Peptide Label: isoform X2
- UniProtKB: Q99N83 (UniProtKB/Swiss-Prot),   Q76MX4 (UniProtKB/Swiss-Prot),   A6HLH1 (UniProtKB/TrEMBL)
Protein Domains
bZIP

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q76MX4-F1-model_v2 AlphaFold Q76MX4 1-189 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13697971
Promoter ID:EPDNEW_R8495
Type:multiple initiation site
Name:Mafg_1
Description:MAF bZIP transcription factor G
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.010109,811,376 - 109,811,436EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:619953 AgrOrtholog
BioCyc Gene G2FUF-22401 BioCyc
Ensembl Genes ENSRNOG00000036697 Ensembl, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00055030545 UniProtKB/Swiss-Prot
  ENSRNOG00060021339 UniProtKB/Swiss-Prot
  ENSRNOG00065004235 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000054970.3 UniProtKB/TrEMBL
  ENSRNOT00000104193.1 UniProtKB/Swiss-Prot
  ENSRNOT00055052990 UniProtKB/Swiss-Prot
  ENSRNOT00055052999 UniProtKB/Swiss-Prot
  ENSRNOT00060037006 UniProtKB/Swiss-Prot
  ENSRNOT00060037018 UniProtKB/Swiss-Prot
  ENSRNOT00065006187 UniProtKB/Swiss-Prot
  ENSRNOT00065006188 UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.5.170 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7127046 IMAGE-MGC_LOAD
InterPro bZIP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  bZIP_Maf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  bZIP_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TF_DNA-bd_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Transciption_factor_Maf_fam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:64188 UniProtKB/Swiss-Prot
MGC_CLONE MGC:93443 IMAGE-MGC_LOAD
NCBI Gene 64188 ENTREZGENE
PANTHER PTHR10129 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR10129:SF15 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam bZIP_Maf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Mafg PhenoGen
PROSITE BZIP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000036697 RatGTEx
  ENSRNOG00055030545 RatGTEx
  ENSRNOG00060021339 RatGTEx
  ENSRNOG00065004235 RatGTEx
SMART BRLZ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF47454 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF57959 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8L2QQP9 ENTREZGENE, UniProtKB/TrEMBL
  A6HLH1 ENTREZGENE, UniProtKB/TrEMBL
  MAFG_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q99N83 ENTREZGENE
UniProt Secondary Q99N83 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-05-18 Mafg  MAF bZIP transcription factor G  Mafg  v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-07-18 Mafg  v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G  Mafg  v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-10-30 Mafg  v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)  Mafg  v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 Mafg  v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian)    v-maf musculoaponeurotic fibrosarcoma (avian) oncogene family, protein G  Name updated 1299863 APPROVED
2002-08-07 Mafg  v-maf musculoaponeurotic fibrosarcoma (avian) oncogene family, protein G      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_transcript splice variant MafG-2 contains an insertion of 27 amino acids 633304