Afmid (arylformamidase) - Rat Genome Database

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Gene: Afmid (arylformamidase) Rattus norvegicus
Analyze
Symbol: Afmid
Name: arylformamidase
RGD ID: 1591143
Description: Predicted to enable arylformamidase activity. Predicted to be involved in L-tryptophan catabolic process to kynurenine. Predicted to be located in cytosol and nucleus. Predicted to be active in cytoplasm. Orthologous to human AFMID (arylformamidase); PARTICIPATES IN kynurenine metabolic pathway; tryptophan metabolic pathway; glyoxylate and dicarboxylate metabolic pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol; 4,4'-sulfonyldiphenol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: kynurenine formamidase; LOC688283; similar to kynurenine formamidase
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr810103,544,822 - 103,560,408 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl10103,544,841 - 103,560,408 (+)EnsemblGRCr8
mRatBN7.210103,046,129 - 103,061,718 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl10103,046,180 - 103,061,718 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx10108,147,221 - 108,162,738 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.010107,610,332 - 107,625,849 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.010102,966,966 - 102,982,504 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.010106,828,963 - 106,844,314 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl10106,828,981 - 106,844,314 (+)Ensemblrn6Rnor6.0
Rnor_5.010106,468,192 - 106,483,539 (+)NCBIRnor_5.0Rnor_5.0rn5
Celera10101,606,154 - 101,621,688 (+)NCBICelera
Cytogenetic Map10q32.2NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1-dichloroethene  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-methylcholine  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3-chloropropane-1,2-diol  (EXP)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
amitrole  (EXP)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
benzo[a]pyrene  (ISO)
beta-lapachone  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
butanal  (ISO)
cadmium dichloride  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
cobalt dichloride  (EXP)
cocaine  (EXP)
copper atom  (ISO)
copper(0)  (ISO)
Cuprizon  (EXP)
cyclosporin A  (ISO)
dibutyl phthalate  (EXP)
doxorubicin  (ISO)
epoxiconazole  (ISO)
fenthion  (ISO)
flutamide  (EXP)
gallic acid  (ISO)
glafenine  (EXP)
indometacin  (EXP)
inulin  (ISO)
leflunomide  (ISO)
Licochalcone B  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (EXP,ISO)
methapyrilene  (EXP)
methimazole  (EXP)
N-methyl-4-phenylpyridinium  (EXP)
N-Nitrosopyrrolidine  (ISO)
nitrofen  (EXP)
paracetamol  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenformin  (EXP)
phenobarbital  (ISO)
potassium dichromate  (ISO)
rotenone  (EXP)
silicon dioxide  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
streptozocin  (EXP)
sunitinib  (ISO)
tetrachloromethane  (ISO)
thioacetamide  (EXP)
triphenyl phosphate  (EXP)
Triptolide  (ISO)
triptonide  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IBA,IEA,ISO)
cytosol  (IEA)
nucleus  (IEA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. The kynurenine pathway and neurodegenerative disease. Maddison DC and Giorgini F, Semin Cell Dev Biol. 2015 Apr;40:134-41. doi: 10.1016/j.semcdb.2015.03.002. Epub 2015 Mar 12.
3. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
4. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12411446   PMID:15632090   PMID:15866519  


Genomics

Comparative Map Data
Afmid
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr810103,544,822 - 103,560,408 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl10103,544,841 - 103,560,408 (+)EnsemblGRCr8
mRatBN7.210103,046,129 - 103,061,718 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl10103,046,180 - 103,061,718 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx10108,147,221 - 108,162,738 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.010107,610,332 - 107,625,849 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.010102,966,966 - 102,982,504 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.010106,828,963 - 106,844,314 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl10106,828,981 - 106,844,314 (+)Ensemblrn6Rnor6.0
Rnor_5.010106,468,192 - 106,483,539 (+)NCBIRnor_5.0Rnor_5.0rn5
Celera10101,606,154 - 101,621,688 (+)NCBICelera
Cytogenetic Map10q32.2NCBI
AFMID
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381778,187,362 - 78,207,702 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1778,187,330 - 78,207,703 (+)Ensemblhg38GRCh38
GRCh371776,183,443 - 76,203,783 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361773,695,038 - 73,715,377 (+)NCBIBuild 36Build 36hg18NCBI36
Celera1772,779,839 - 72,799,987 (+)NCBICelera
Cytogenetic Map17q25.3NCBI
HuRef1771,607,490 - 71,627,902 (+)NCBIHuRef
CHM1_11776,247,936 - 76,268,306 (+)NCBICHM1_1
T2T-CHM13v2.01779,081,456 - 79,101,795 (+)NCBIT2T-CHM13v2.0
Afmid
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911117,716,329 - 117,730,734 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl11117,716,750 - 117,730,734 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm3811117,825,503 - 117,839,908 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11117,825,924 - 117,839,908 (+)Ensemblmm10GRCm38
MGSCv3711117,687,233 - 117,701,222 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv3611117,642,014 - 117,655,995 (+)NCBIMGSCv36mm8
Celera11129,570,944 - 129,584,931 (+)NCBICelera
Cytogenetic Map11E2NCBI
cM Map1182.96NCBI
Afmid
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555064,365,926 - 4,379,447 (-)Ensembl
ChiLan1.0NW_0049555064,351,623 - 4,379,528 (-)NCBIChiLan1.0ChiLan1.0
AFMID
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21994,238,074 - 94,258,492 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11799,067,531 - 99,087,942 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01772,265,365 - 72,285,764 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11777,831,451 - 77,836,671 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1777,816,908 - 77,835,905 (+)EnsemblpanPan2panpan1.1
AFMID
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Dog10K_Boxer_Tasha93,623,404 - 3,642,846 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.093,617,752 - 3,637,159 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl93,606,546 - 3,637,375 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.193,640,828 - 3,660,237 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.093,765,021 - 3,784,444 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.093,846,437 - 3,865,874 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Afmid
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244056023,599,706 - 3,618,352 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365942,794,894 - 2,808,100 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365942,794,927 - 2,805,689 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AFMID
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl123,759,708 - 3,785,835 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1123,759,688 - 3,785,829 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
AFMID
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11670,200,453 - 70,224,190 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236678021,136 - 6,968 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Afmid
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248017,693,022 - 7,715,242 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248017,692,928 - 7,715,902 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Afmid
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1966,225,041 - 66,239,986 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Afmid
82 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:445
Count of miRNA genes:217
Interacting mature miRNAs:260
Transcripts:ENSRNOT00000073809
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
7387312Bw125Body weight QTL 12530.0047retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight (CMO:0000356)1065390777107713808Rat
1354641Bvd2Brain ventricular dilatation QTL 26.360.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)1093723381107556066Rat
8657410Bp374Blood pressure QTL 374heart left ventricle size trait (VT:0002753)heart left ventricle end-diastolic diameter (CMO:0000982)1067476608107713808Rat
61449Ciaa2CIA Autoantibody QTL 27.1blood autoantibody amount (VT:0003725)calculated serum anti-type 2 collagen antibody titer (CMO:0001279)1063719161107713808Rat
61387Bp1Blood pressure QTL 15.1arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)1052269185107713808Rat
61325Aia5Adjuvant induced arthritis QTL 50.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023948641107713808Rat
1298078Stresp5Stress response QTL 52.990.00025blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)1042546145107713808Rat
12903252Cm113Cardiac mass QTL 1130.047heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)1066817119107713808Rat
61396Bp9Blood pressure QTL 94.80.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1068920187107713808Rat
2298548Neuinf7Neuroinflammation QTL 73.4nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)1064939013107713808Rat
1358915Stresp7Stress response QTL 73.52blood norepinephrine amount (VT:0005663)plasma norepinephrine level (CMO:0001010)1065307813107713808Rat
1302404Cia27Collagen induced arthritis QTL 272.60.0045joint integrity trait (VT:0010548)experimental arthritis severity measurement (CMO:0001459)1076951790107713808Rat
70168Eae12Experimental allergic encephalomyelitis QTL 120.0009nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)1073599825107713808Rat
634320Niddm49Non-insulin dependent diabetes mellitus QTL 494.41blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)1089039175107713808Rat
70171Cari1Carrageenan-induced inflammation QTL 14.90.0005hypodermis integrity trait (VT:0010550)inflammatory exudate volume (CMO:0001429)1054296227107713808Rat
70363Bp71Blood pressure QTL 710.04arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1061843496106843496Rat
6893366Bw106Body weight QTL 1060.30.47body mass (VT:0001259)body weight (CMO:0000012)1070698731107713808Rat
12903269Am15Aortic mass QTL 150.042aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)1066817119107713808Rat
1576313Pia25Pristane induced arthritis QTL 25joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1096620293107713808Rat
12903266Cm114Cardiac mass QTL 1140.02heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)1066817119107713808Rat
1578672Bmd16Bone mineral density QTL 166.2femur mineral mass (VT:0010011)compact volumetric bone mineral density (CMO:0001730)1097202388107556066Rat
61354Pia10Pristane induced arthritis QTL 100.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023948641107713808Rat
631267Cia20Collagen induced arthritis QTL 203.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023948641107713808Rat
1576307Cia28Collagen induced arthritis QTL 28joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1096620293107713808Rat
631269Cia22Collagen induced arthritis QTL 228.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1040535708107713808Rat
1576308Schws1Schwannoma susceptibility QTL 10.0041nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)1040535708107713808Rat
2313103Bss80Bone structure and strength QTL 8020.0001tibia strength trait (VT:1000284)tibia midshaft endosteal cross-sectional area (CMO:0001716)1062556066107556066Rat
631268Cia21Collagen induced arthritis QTL 213.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1014991535107713808Rat
631270Cia23Collagen induced arthritis QTL 233.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1040535708107713808Rat
1581559Eae18Experimental allergic encephalomyelitis QTL 180.00002nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)1066108888107555881Rat
12880372Am12Aortic mass QTL 120.003aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)1066817119107713808Rat
70193Mcs7Mammary carcinoma susceptibility QTL 72.38mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1072724423107713808Rat
2313105Bss79Bone structure and strength QTL 791.80.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)1062556066107556066Rat
12880375Kidm66Kidney mass QTL 660.009kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)1066817119107713808Rat
61363Oia3Oil induced arthritis QTL 30.001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1087807758107713808Rat
2316949Gluco60Glucose level QTL 603.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1014991535107556066Rat
12880370Cm105Cardiac mass QTL 1050.008heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)1066817119107713808Rat
12880371Cm106Cardiac mass QTL 1060.007heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)1066817119107713808Rat
1600367Mcs15Mammary carcinoma susceptibility QTL 154.5mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1072724423107713808Rat
631537Oia4Oil induced arthritis QTL 4joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1076128947107713808Rat
1300137Bp186Blood pressure QTL 1863.57arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)1091127270107556066Rat
634354Rends3Renal damage susceptibility QTL 30.05kidney blood vessel morphology trait (VT:0000530)organ lesion measurement (CMO:0000677)1061997479106997479Rat
61436Cia5Collagen induced arthritis QTL 54.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1091727883107713808Rat
11565453Kidm58Kidney mass QTL 580.002kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)1066817119107713808Rat
2301405Cm69Cardiac mass QTL 690.031heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)1066817119107713808Rat
1578663Bss18Bone structure and strength QTL 183.6femur width (VT:1000666)femoral neck width (CMO:0001695)1097202388107556066Rat

Markers in Region
RH132297  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.210103,055,929 - 103,057,382 (+)MAPPERmRatBN7.2
Rnor_6.010106,838,731 - 106,840,183NCBIRnor6.0
Rnor_5.010106,477,956 - 106,479,408UniSTSRnor5.0
Celera10101,615,901 - 101,617,353UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 163 91 90 59 92 59 6 356 192 11 142 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000073809   ⟹   ENSRNOP00000067187
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl10103,544,874 - 103,560,408 (+)Ensembl
mRatBN7.2 Ensembl10103,046,180 - 103,061,718 (+)Ensembl
Rnor_6.0 Ensembl10106,828,981 - 106,844,314 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000097429   ⟹   ENSRNOP00000088380
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl10103,544,841 - 103,557,683 (+)Ensembl
mRatBN7.2 Ensembl10103,046,180 - 103,058,992 (+)Ensembl
RefSeq Acc Id: NM_001111366   ⟹   NP_001104836
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr810103,544,874 - 103,560,408 (+)NCBI
mRatBN7.210103,046,180 - 103,061,718 (+)NCBI
Rnor_6.010106,828,981 - 106,844,314 (+)NCBI
Rnor_5.010106,468,192 - 106,483,539 (+)NCBI
Celera10101,606,154 - 101,621,688 (+)RGD
Sequence:
RefSeq Acc Id: XM_006247823   ⟹   XP_006247885
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr810103,544,823 - 103,559,898 (+)NCBI
mRatBN7.210103,046,131 - 103,061,205 (+)NCBI
Rnor_6.010106,828,966 - 106,843,801 (+)NCBI
Rnor_5.010106,468,192 - 106,483,539 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017597530   ⟹   XP_017453019
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr810103,544,822 - 103,556,693 (+)NCBI
mRatBN7.210103,046,129 - 103,057,692 (+)NCBI
Rnor_6.010106,828,963 - 106,840,424 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063269865   ⟹   XP_063125935
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr810103,544,823 - 103,557,476 (+)NCBI
RefSeq Acc Id: XM_063269866   ⟹   XP_063125936
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr810103,547,343 - 103,557,476 (+)NCBI
RefSeq Acc Id: XM_063269867   ⟹   XP_063125937
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr810103,544,836 - 103,557,476 (+)NCBI
RefSeq Acc Id: XM_063269868   ⟹   XP_063125938
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr810103,547,343 - 103,559,898 (+)NCBI
RefSeq Acc Id: XM_063269870   ⟹   XP_063125940
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr810103,547,343 - 103,559,898 (+)NCBI
RefSeq Acc Id: NP_001104836   ⟸   NM_001111366
- UniProtKB: M0RC77 (UniProtKB/TrEMBL),   A6HL34 (UniProtKB/TrEMBL),   A0A8I6GH15 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006247885   ⟸   XM_006247823
- Peptide Label: isoform X3
- UniProtKB: A0A8I6GH15 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017453019   ⟸   XM_017597530
- Peptide Label: isoform X2
- UniProtKB: A0A8I6GH15 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000067187   ⟸   ENSRNOT00000073809
Ensembl Acc Id: ENSRNOP00000088380   ⟸   ENSRNOT00000097429
RefSeq Acc Id: XP_063125935   ⟸   XM_063269865
- Peptide Label: isoform X1
- UniProtKB: A0A8I6GH15 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063125937   ⟸   XM_063269867
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063125938   ⟸   XM_063269868
- Peptide Label: isoform X5
RefSeq Acc Id: XP_063125940   ⟸   XM_063269870
- Peptide Label: isoform X6
RefSeq Acc Id: XP_063125936   ⟸   XM_063269866
- Peptide Label: isoform X4
Protein Domains
BD-FAE-like

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-M0RC77-F1-model_v2 AlphaFold M0RC77 1-306 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13697933
Promoter ID:EPDNEW_R8458
Type:multiple initiation site
Name:Afmid_1
Description:arylformamidase
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.010106,829,001 - 106,829,061EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1591143 AgrOrtholog
BioCyc Gene G2FUF-22537 BioCyc
BioCyc Pathway PWY-5651 [L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde] BioCyc
BioCyc Pathway Image PWY-5651 BioCyc
Ensembl Genes ENSRNOG00000050205 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000073809 ENTREZGENE
  ENSRNOT00000073809.3 UniProtKB/TrEMBL
  ENSRNOT00000097429 ENTREZGENE
  ENSRNOT00000097429.2 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.1820 UniProtKB/TrEMBL
InterPro AB_hydrolase UniProtKB/TrEMBL
  BD-FAE-like_dom UniProtKB/TrEMBL
  GDXG_lipolytic_enzyme UniProtKB/TrEMBL
  KFase UniProtKB/TrEMBL
KEGG Report rno:688283 UniProtKB/TrEMBL
NCBI Gene 688283 ENTREZGENE
PANTHER AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C UniProtKB/TrEMBL
  KYNURENINE FORMAMIDASE UniProtKB/TrEMBL
Pfam BD-FAE UniProtKB/TrEMBL
PhenoGen Afmid PhenoGen
RatGTEx ENSRNOG00000050205 RatGTEx
Superfamily-SCOP SSF53474 UniProtKB/TrEMBL
UniProt A0A8I6GH15 ENTREZGENE, UniProtKB/TrEMBL
  A6HL34 ENTREZGENE, UniProtKB/TrEMBL
  M0RC77 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-09-23 Afmid  arylformamidase  LOC688283  similar to kynurenine formamidase  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-20 LOC688283  similar to kynurenine formamidase      Symbol and Name status set to provisional 70820 PROVISIONAL