Symbol:
Fdxr
Name:
ferredoxin reductase
RGD ID:
621648
Description:
Enables NADPH binding activity and NADPH-adrenodoxin reductase activity. Involved in NADPH oxidation. Located in mitochondrion. Orthologous to human FDXR (ferredoxin reductase); PARTICIPATES IN aldosterone biosynthetic pathway; cortisol biosynthetic pathway; estradiol biosynthetic pathway; INTERACTS WITH (+)-schisandrin B; 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 17alpha-ethynylestradiol.
Type:
protein-coding
RefSeq Status:
PROVISIONAL
Previously known as:
adrenodoxin reductase; AR; ferredoxin--NADP(+) reductase; NADPH:adrenodoxin oxidoreductase, mitochondrial
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
FDXR (ferredoxin reductase) HGNC
Ensembl, HomoloGene, Inparanoid, NCBI, Panther, PhylomeDB
Mus musculus (house mouse):
Fdxr (ferredoxin reductase) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):
Fdxr (ferredoxin reductase) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
FDXR (ferredoxin reductase) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
FDXR (ferredoxin reductase) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Fdxr (ferredoxin reductase) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
FDXR (ferredoxin reductase) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):
FDXR (ferredoxin reductase) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):
Fdxr (ferredoxin reductase) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Alliance orthologs 3
Homo sapiens (human):
FDXR (ferredoxin reductase)
Alliance
DIOPT (HGNC|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Mus musculus (house mouse):
Fdxr (ferredoxin reductase)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Danio rerio (zebrafish):
fdxr (ferredoxin reductase)
Alliance
DIOPT (Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):
ARH1
Alliance
DIOPT (Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Caenorhabditis elegans (roundworm):
Y62E10A.6
Alliance
DIOPT (Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Drosophila melanogaster (fruit fly):
dare
Alliance
DIOPT (Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):
fdxr
Alliance
DIOPT (Ensembl Compara|OMA|OrthoFinder|PANTHER|PhylomeDB)
Latest Assembly:
GRCr8 - GRCr8 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 10 101,006,845 - 101,015,582 (-) NCBI GRCr8 mRatBN7.2 10 100,507,863 - 100,516,649 (-) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 10 100,507,865 - 100,516,658 (-) Ensembl mRatBN7.2 Ensembl UTH_Rnor_SHR_Utx 10 105,568,049 - 105,576,738 (-) NCBI Rnor_SHR UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 10 105,031,109 - 105,039,798 (-) NCBI Rnor_SHRSP UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 10 100,428,857 - 100,437,546 (-) NCBI Rnor_WKY UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 10 103,817,724 - 103,826,413 (-) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 10 103,817,704 - 103,826,448 (-) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 10 104,468,590 - 104,477,279 (+) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 10 105,342,684 - 105,351,374 (-) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 RGSC_v3.1 10 105,357,187 - 105,365,878 (-) NCBI Celera 10 99,084,255 - 99,092,947 (-) NCBI Celera Cytogenetic Map 10 q32.1 NCBI
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Only show annotations with direct experimental evidence (0 objects hidden)
Fdxr Rat (+)-schisandrin B multiple interactions EXP 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of FDXR mRNA] CTD PMID:31150632 Fdxr Rat (-)-demecolcine increases expression ISO FDXR (Homo sapiens) 6480464 Demecolcine results in increased expression of FDXR mRNA CTD PMID:23649840 Fdxr Rat (1->4)-beta-D-glucan multiple interactions ISO Fdxr (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of FDXR mRNA CTD PMID:36331819 Fdxr Rat (S)-colchicine decreases expression ISO FDXR (Homo sapiens) 6480464 Colchicine results in decreased expression of FDXR mRNA CTD PMID:24211769 Fdxr Rat 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane multiple interactions EXP 6480464 2 more ... CTD PMID:19414516 Fdxr Rat 1,2-dimethylhydrazine multiple interactions ISO Fdxr (Mus musculus) 6480464 [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of FDXR mRNA CTD PMID:22206623 Fdxr Rat 17alpha-ethynylestradiol multiple interactions ISO Fdxr (Mus musculus) 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of FDXR mRNA CTD PMID:17942748 Fdxr Rat 17alpha-ethynylestradiol decreases expression EXP 6480464 Ethinyl Estradiol results in decreased expression of FDXR mRNA CTD PMID:12655037 and PMID:17557909 Fdxr Rat 17beta-estradiol multiple interactions ISO FDXR (Homo sapiens) 6480464 [Estradiol co-treated with TGFB1 protein] results in decreased expression of FDXR mRNA CTD PMID:30165855 Fdxr Rat 2,2',4,4'-Tetrabromodiphenyl ether affects expression ISO Fdxr (Mus musculus) 6480464 2 more ... CTD PMID:30294300 Fdxr Rat 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO Fdxr (Mus musculus) 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of FDXR mRNA CTD PMID:17942748 Fdxr Rat 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Fdxr (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of FDXR mRNA CTD PMID:21570461 Fdxr Rat 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of FDXR mRNA CTD PMID:21215274 and PMID:32109520 Fdxr Rat 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO FDXR (Homo sapiens) 6480464 pifithrin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of FDXR mRNA] CTD PMID:20064835 Fdxr Rat 2,4-dinitrotoluene affects expression EXP 6480464 2 and 4-dinitrotoluene affects the expression of FDXR mRNA CTD PMID:21346803 Fdxr Rat 2,6-dimethoxyphenol multiple interactions ISO FDXR (Homo sapiens) 6480464 [Sodium Chloride co-treated with pyrogallol 1 and 3-dimethyl ether] results in increased expression of FDXR protein CTD PMID:38598786 Fdxr Rat 3,3',4,4',5-pentachlorobiphenyl decreases expression EXP 6480464 3 more ... CTD PMID:23196670 Fdxr Rat 3-chloropropane-1,2-diol decreases expression EXP 6480464 alpha-Chlorohydrin results in decreased expression of FDXR protein CTD PMID:26072098 Fdxr Rat 3-methylcholanthrene increases expression ISO FDXR (Homo sapiens) 6480464 Methylcholanthrene results in increased expression of FDXR mRNA CTD PMID:22100608 Fdxr Rat 4,4'-diaminodiphenylmethane decreases expression ISO Fdxr (Mus musculus) 6480464 4 and 4'-diaminodiphenylmethane results in decreased expression of FDXR mRNA CTD PMID:18648102 Fdxr Rat 4,4'-sulfonyldiphenol increases expression ISO FDXR (Homo sapiens) 6480464 bisphenol S results in increased expression of FDXR protein CTD PMID:34186270 Fdxr Rat 4-amino-2,6-dinitrotoluene affects expression EXP 6480464 4-amino-2 and 6-dinitrotoluene affects the expression of FDXR mRNA CTD PMID:21346803 Fdxr Rat 5-fluorouracil multiple interactions ISO FDXR (Homo sapiens) 6480464 TP53 protein affects the reaction [Fluorouracil results in increased expression of FDXR mRNA] more ... CTD PMID:15016801 more ... Fdxr Rat 5-fluorouracil increases expression ISO FDXR (Homo sapiens) 6480464 Fluorouracil results in increased expression of FDXR mRNA more ... CTD PMID:14665630 more ... Fdxr Rat 8-Br-cAMP increases expression ISO Fdxr (Mus musculus) 6480464 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of FDXR protein CTD PMID:24740604 Fdxr Rat 8-Br-cAMP multiple interactions ISO Fdxr (Mus musculus) 6480464 Hydrocarbons and Chlorinated inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of FDXR protein] CTD PMID:24740604 Fdxr Rat acetamide decreases expression EXP 6480464 acetamide results in decreased expression of FDXR mRNA CTD PMID:31881176 Fdxr Rat actinomycin D multiple interactions ISO FDXR (Homo sapiens) 6480464 [Dactinomycin co-treated with nutlin 3] results in increased expression of and results in increased secretion of FDXR protein CTD PMID:38460933 Fdxr Rat adenine decreases expression ISO FDXR (Homo sapiens) 6480464 Adenine results in decreased expression of FDXR mRNA CTD PMID:24211769 Fdxr Rat aflatoxin B1 affects expression ISO FDXR (Homo sapiens) 6480464 Aflatoxin B1 affects the expression of FDXR protein CTD PMID:20106945 Fdxr Rat aflatoxin B1 increases expression ISO FDXR (Homo sapiens) 6480464 Aflatoxin B1 results in increased expression of FDXR mRNA CTD PMID:21632981 more ... Fdxr Rat aflatoxin B1 multiple interactions ISO FDXR (Homo sapiens) 6480464 TP53 protein affects the reaction [Aflatoxin B1 results in increased expression of FDXR mRNA] CTD PMID:22100608 Fdxr Rat alpha-Zearalanol multiple interactions EXP 6480464 [Zeranol co-treated with perfluorooctanoic acid] results in increased expression of FDXR mRNA CTD PMID:35163327 Fdxr Rat ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of FDXR mRNA CTD PMID:16483693 Fdxr Rat aristolochic acid A increases expression ISO FDXR (Homo sapiens) 6480464 aristolochic acid I results in increased expression of FDXR mRNA CTD PMID:33212167 Fdxr Rat arsane affects methylation ISO FDXR (Homo sapiens) 6480464 Arsenic affects the methylation of FDXR gene CTD PMID:25304211 Fdxr Rat arsane multiple interactions ISO FDXR (Homo sapiens) 6480464 [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in decreased expression of FDXR mRNA CTD PMID:39836092 Fdxr Rat arsenic atom affects methylation ISO FDXR (Homo sapiens) 6480464 Arsenic affects the methylation of FDXR gene CTD PMID:25304211 Fdxr Rat arsenic atom multiple interactions ISO FDXR (Homo sapiens) 6480464 [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in decreased expression of FDXR mRNA CTD PMID:39836092 Fdxr Rat atrazine increases expression ISO FDXR (Homo sapiens) 6480464 Atrazine results in increased expression of FDXR mRNA CTD PMID:22378314 Fdxr Rat benzene-1,2,4-triol increases expression ISO FDXR (Homo sapiens) 6480464 hydroxyhydroquinone results in increased expression of FDXR mRNA CTD PMID:17572062 Fdxr Rat benzo[a]pyrene increases expression ISO Fdxr (Mus musculus) 6480464 Benzo(a)pyrene results in increased expression of FDXR mRNA CTD PMID:22228805 Fdxr Rat benzo[a]pyrene increases expression ISO FDXR (Homo sapiens) 6480464 Benzo(a)pyrene results in increased expression of FDXR mRNA CTD PMID:20064835 more ... Fdxr Rat benzo[a]pyrene diol epoxide I increases expression ISO FDXR (Homo sapiens) 6480464 7 more ... CTD PMID:20382639 and PMID:26238291 Fdxr Rat beta-lapachone decreases expression ISO FDXR (Homo sapiens) 6480464 beta-lapachone results in decreased expression of FDXR mRNA CTD PMID:38218311 Fdxr Rat bis(2-chloroethyl) sulfide increases expression ISO Fdxr (Mus musculus) 6480464 Mustard Gas results in increased expression of FDXR mRNA CTD PMID:15674844 Fdxr Rat bis(2-ethylhexyl) phthalate increases expression ISO Fdxr (Mus musculus) 6480464 Diethylhexyl Phthalate results in increased expression of FDXR mRNA CTD PMID:33162236 Fdxr Rat bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of FDXR mRNA CTD PMID:25181051 more ... Fdxr Rat bisphenol A decreases expression ISO Fdxr (Mus musculus) 6480464 bisphenol A results in decreased expression of FDXR mRNA CTD PMID:32156529 and PMID:35598803 Fdxr Rat bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of FDXR mRNA CTD PMID:34947998 Fdxr Rat bisphenol A increases expression ISO Fdxr (Mus musculus) 6480464 bisphenol A results in increased expression of FDXR mRNA CTD PMID:33221593 Fdxr Rat bisphenol A decreases expression ISO FDXR (Homo sapiens) 6480464 bisphenol A results in decreased expression of FDXR mRNA and bisphenol A results in decreased expression of FDXR protein CTD PMID:33258555 and PMID:34186270 Fdxr Rat bisphenol A increases expression ISO FDXR (Homo sapiens) 6480464 bisphenol A results in increased expression of FDXR mRNA and bisphenol A results in increased expression of FDXR protein CTD PMID:29275510 and PMID:33024228 Fdxr Rat bisphenol A affects expression ISO FDXR (Homo sapiens) 6480464 bisphenol A affects the expression of FDXR mRNA CTD PMID:30903817 Fdxr Rat bisphenol A decreases methylation ISO Fdxr (Mus musculus) 6480464 bisphenol A results in decreased methylation of FDXR promoter CTD PMID:27312807 Fdxr Rat Bisphenol B increases expression ISO FDXR (Homo sapiens) 6480464 bisphenol B results in increased expression of FDXR protein CTD PMID:34186270 Fdxr Rat bisphenol F decreases expression ISO Fdxr (Mus musculus) 6480464 bisphenol F results in decreased expression of FDXR mRNA CTD PMID:38685157 Fdxr Rat bisphenol F increases expression ISO FDXR (Homo sapiens) 6480464 bisphenol F results in increased expression of FDXR protein CTD PMID:34186270 Fdxr Rat Brodifacoum increases expression EXP 6480464 bromfenacoum results in increased expression of FDXR protein CTD PMID:28903499 Fdxr Rat cadmium dichloride increases expression ISO FDXR (Homo sapiens) 6480464 Cadmium Chloride results in increased expression of FDXR protein CTD PMID:24527689 Fdxr Rat cadmium dichloride decreases expression ISO FDXR (Homo sapiens) 6480464 Cadmium Chloride results in decreased expression of FDXR mRNA CTD PMID:38568856 Fdxr Rat camptothecin increases expression ISO FDXR (Homo sapiens) 6480464 Camptothecin results in increased expression of FDXR mRNA CTD PMID:17374387 Fdxr Rat carbamazepine affects expression ISO FDXR (Homo sapiens) 6480464 Carbamazepine affects the expression of FDXR mRNA CTD PMID:25979313 Fdxr Rat carbon nanotube decreases expression ISO Fdxr (Mus musculus) 6480464 Nanotubes more ... CTD PMID:25620056 Fdxr Rat chlorohydrocarbon multiple interactions ISO Fdxr (Mus musculus) 6480464 Hydrocarbons and Chlorinated inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of FDXR protein] CTD PMID:24740604 Fdxr Rat chromium(6+) multiple interactions ISO FDXR (Homo sapiens) 6480464 [zinc chromate results in increased abundance of chromium hexavalent ion] which results in increased expression of FDXR mRNA CTD PMID:38479592 Fdxr Rat cisplatin multiple interactions ISO FDXR (Homo sapiens) 6480464 [Cisplatin co-treated with jinfukang] results in increased expression of FDXR mRNA and [Piroxicam co-treated with Cisplatin] results in decreased expression of FDXR mRNA CTD PMID:21858171 and PMID:27392435 Fdxr Rat cisplatin increases expression ISO FDXR (Homo sapiens) 6480464 Cisplatin results in increased expression of FDXR mRNA CTD PMID:19561079 more ... Fdxr Rat clofibrate decreases expression ISO Fdxr (Mus musculus) 6480464 Clofibrate results in decreased expression of FDXR mRNA CTD PMID:23811191 Fdxr Rat cobalt atom multiple interactions ISO FDXR (Homo sapiens) 6480464 [tungsten carbide co-treated with Cobalt] results in increased expression of FDXR mRNA CTD PMID:18078969 and PMID:23052192 Fdxr Rat cobalt dichloride increases expression ISO FDXR (Homo sapiens) 6480464 cobaltous chloride results in increased expression of FDXR mRNA CTD PMID:19376846 Fdxr Rat cyclosporin A decreases expression ISO FDXR (Homo sapiens) 6480464 Cyclosporine results in decreased expression of FDXR mRNA CTD PMID:20106945 more ... Fdxr Rat daunorubicin increases expression ISO FDXR (Homo sapiens) 6480464 Daunorubicin results in increased expression of FDXR mRNA CTD PMID:17374387 Fdxr Rat DDE increases expression ISO FDXR (Homo sapiens) 6480464 Dichlorodiphenyl Dichloroethylene results in increased expression of FDXR mRNA CTD PMID:38568856 Fdxr Rat dextran sulfate decreases expression ISO Fdxr (Mus musculus) 6480464 Dextran Sulfate results in decreased expression of FDXR mRNA CTD PMID:35093514 Fdxr Rat Dibutyl phosphate affects expression ISO FDXR (Homo sapiens) 6480464 di-n-butylphosphoric acid affects the expression of FDXR mRNA CTD PMID:37042841 Fdxr Rat dibutyl phthalate decreases expression ISO Fdxr (Mus musculus) 6480464 Dibutyl Phthalate results in decreased expression of FDXR mRNA CTD PMID:21266533 Fdxr Rat dibutyl phthalate decreases expression EXP 6480464 Dibutyl Phthalate results in decreased expression of FDXR mRNA CTD PMID:17379624 more ... Fdxr Rat disodium selenite increases expression ISO FDXR (Homo sapiens) 6480464 Sodium Selenite results in increased expression of FDXR mRNA CTD PMID:24383545 Fdxr Rat dorsomorphin multiple interactions ISO FDXR (Homo sapiens) 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of FDXR mRNA CTD PMID:27188386 Fdxr Rat doxorubicin increases expression ISO FDXR (Homo sapiens) 6480464 Doxorubicin results in increased expression of FDXR mRNA CTD PMID:15205334 more ... Fdxr Rat entinostat increases expression ISO FDXR (Homo sapiens) 6480464 entinostat results in increased expression of FDXR mRNA CTD PMID:26272509 Fdxr Rat entinostat multiple interactions ISO FDXR (Homo sapiens) 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of FDXR mRNA CTD PMID:27188386 Fdxr Rat ethyl methanesulfonate increases expression ISO FDXR (Homo sapiens) 6480464 Ethyl Methanesulfonate results in increased expression of FDXR mRNA CTD PMID:23649840 Fdxr Rat etoposide increases expression ISO FDXR (Homo sapiens) 6480464 Etoposide results in increased expression of FDXR mRNA CTD PMID:17374387 Fdxr Rat flavonoids increases expression EXP 6480464 Flavonoids results in increased expression of FDXR mRNA CTD PMID:18035473 Fdxr Rat flutamide increases expression EXP 6480464 Flutamide results in increased expression of FDXR mRNA CTD PMID:19299419 Fdxr Rat folic acid multiple interactions ISO Fdxr (Mus musculus) 6480464 [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of FDXR mRNA CTD PMID:22206623 Fdxr Rat formaldehyde increases expression ISO FDXR (Homo sapiens) 6480464 Formaldehyde results in increased expression of FDXR mRNA CTD PMID:23649840 Fdxr Rat FR900359 increases phosphorylation ISO FDXR (Homo sapiens) 6480464 FR900359 results in increased phosphorylation of FDXR protein CTD PMID:37730182 Fdxr Rat furfural multiple interactions ISO FDXR (Homo sapiens) 6480464 [Sodium Chloride co-treated with Furaldehyde] results in decreased expression of FDXR protein CTD PMID:38598786 Fdxr Rat glafenine decreases expression EXP 6480464 Glafenine results in decreased expression of FDXR mRNA CTD PMID:24136188 Fdxr Rat hydrogen peroxide increases expression ISO FDXR (Homo sapiens) 6480464 Hydrogen Peroxide results in increased expression of FDXR mRNA CTD PMID:12414654 Fdxr Rat hydrogen peroxide decreases expression ISO FDXR (Homo sapiens) 6480464 Hydrogen Peroxide results in decreased expression of FDXR protein CTD PMID:34581912 Fdxr Rat hydrogen peroxide multiple interactions ISO FDXR (Homo sapiens) 6480464 [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of FDXR protein CTD PMID:18951874 Fdxr Rat indometacin increases expression EXP 6480464 Indomethacin results in increased expression of FDXR mRNA CTD PMID:18299717 Fdxr Rat ivermectin decreases expression ISO FDXR (Homo sapiens) 6480464 Ivermectin results in decreased expression of FDXR protein CTD PMID:32959892 Fdxr Rat L-ascorbic acid increases expression EXP 6480464 Ascorbic Acid results in increased expression of FDXR mRNA CTD PMID:15372504 Fdxr Rat lamivudine multiple interactions ISO Fdxr (Mus musculus) 6480464 [Zidovudine co-treated with Lamivudine] results in increased expression of FDXR mRNA CTD PMID:18313992 Fdxr Rat lipopolysaccharide decreases expression ISO FDXR (Homo sapiens) 6480464 Lipopolysaccharides results in decreased expression of FDXR mRNA CTD PMID:31059760 Fdxr Rat manganese atom multiple interactions ISO FDXR (Homo sapiens) 6480464 [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in decreased expression of FDXR mRNA CTD PMID:39836092 Fdxr Rat manganese(0) multiple interactions ISO FDXR (Homo sapiens) 6480464 [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in decreased expression of FDXR mRNA CTD PMID:39836092 Fdxr Rat manganese(II) chloride multiple interactions ISO FDXR (Homo sapiens) 6480464 [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in decreased expression of FDXR mRNA CTD PMID:39836092 Fdxr Rat menadione affects expression ISO FDXR (Homo sapiens) 6480464 Vitamin K 3 affects the expression of FDXR mRNA CTD PMID:20044591 Fdxr Rat menadione increases expression ISO FDXR (Homo sapiens) 6480464 Vitamin K 3 results in increased expression of FDXR mRNA CTD PMID:12414654 Fdxr Rat methyl methanesulfonate increases expression ISO FDXR (Homo sapiens) 6480464 Methyl Methanesulfonate results in increased expression of FDXR mRNA CTD PMID:22100608 and PMID:23649840 Fdxr Rat mono(2-ethylhexyl) phthalate decreases expression ISO Fdxr (Mus musculus) 6480464 mono-(2-ethylhexyl)phthalate results in decreased expression of FDXR mRNA CTD PMID:22401849 Fdxr Rat N-methyl-4-phenylpyridinium increases expression ISO Fdxr (Mus musculus) 6480464 1-Methyl-4-phenylpyridinium results in increased expression of FDXR mRNA CTD PMID:22776087 Fdxr Rat Nutlin-3 multiple interactions ISO FDXR (Homo sapiens) 6480464 [Dactinomycin co-treated with nutlin 3] results in increased expression of and results in increased secretion of FDXR protein CTD PMID:38460933 Fdxr Rat ozone decreases expression EXP 6480464 Ozone results in decreased expression of FDXR mRNA CTD PMID:28623178 Fdxr Rat paracetamol affects expression ISO Fdxr (Mus musculus) 6480464 Acetaminophen affects the expression of FDXR mRNA CTD PMID:17562736 Fdxr Rat paracetamol increases expression ISO FDXR (Homo sapiens) 6480464 Acetaminophen results in increased expression of FDXR mRNA CTD PMID:22230336 and PMID:25704631 Fdxr Rat perfluorooctane-1-sulfonic acid multiple interactions ISO Fdxr (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of FDXR mRNA CTD PMID:36331819 Fdxr Rat perfluorooctanoic acid multiple interactions EXP 6480464 [Zeranol co-treated with perfluorooctanoic acid] results in increased expression of FDXR mRNA CTD PMID:35163327 Fdxr Rat pifithrin-alpha hydrobromide multiple interactions ISO FDXR (Homo sapiens) 6480464 pifithrin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of FDXR mRNA] CTD PMID:20064835 Fdxr Rat piroxicam multiple interactions ISO FDXR (Homo sapiens) 6480464 [Piroxicam co-treated with Cisplatin] results in decreased expression of FDXR mRNA CTD PMID:21858171 Fdxr Rat potassium dichromate increases expression ISO FDXR (Homo sapiens) 6480464 Potassium Dichromate results in increased expression of FDXR protein CTD PMID:23718831 Fdxr Rat propanal increases expression ISO FDXR (Homo sapiens) 6480464 propionaldehyde results in increased expression of FDXR mRNA CTD PMID:26079696 Fdxr Rat quercetin increases expression ISO FDXR (Homo sapiens) 6480464 Quercetin results in increased expression of FDXR mRNA CTD PMID:21632981 Fdxr Rat resveratrol increases expression ISO FDXR (Homo sapiens) 6480464 resveratrol results in increased expression of FDXR mRNA CTD PMID:25888808 Fdxr Rat SB 431542 multiple interactions ISO FDXR (Homo sapiens) 6480464 [LDN 193189 co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 and PMID:37664457 Fdxr Rat sodium arsenite increases expression EXP 6480464 sodium arsenite results in increased expression of FDXR protein CTD PMID:29459688 Fdxr Rat sodium arsenite multiple interactions ISO FDXR (Homo sapiens) 6480464 [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in decreased expression of FDXR mRNA CTD PMID:39836092 Fdxr Rat sodium arsenite increases expression ISO FDXR (Homo sapiens) 6480464 sodium arsenite results in increased expression of FDXR mRNA CTD PMID:34032870 Fdxr Rat sodium arsenite decreases expression ISO FDXR (Homo sapiens) 6480464 sodium arsenite results in decreased expression of FDXR mRNA CTD PMID:38568856 Fdxr Rat sodium chloride multiple interactions ISO FDXR (Homo sapiens) 6480464 [Sodium Chloride co-treated with Furaldehyde] results in decreased expression of FDXR protein more ... CTD PMID:38598786 Fdxr Rat sodium fluoride increases expression ISO Fdxr (Mus musculus) 6480464 Sodium Fluoride results in increased expression of FDXR mRNA CTD PMID:21340527 Fdxr Rat sotorasib multiple interactions ISO FDXR (Homo sapiens) 6480464 [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of FDXR mRNA CTD PMID:36139627 Fdxr Rat tert-butyl hydroperoxide increases expression ISO FDXR (Homo sapiens) 6480464 tert-Butylhydroperoxide results in increased expression of FDXR mRNA CTD PMID:12414654 and PMID:27509014 Fdxr Rat tetrachloroethene decreases expression ISO Fdxr (Mus musculus) 6480464 Tetrachloroethylene results in decreased expression of FDXR mRNA CTD PMID:28973375 Fdxr Rat tetrachloromethane multiple interactions EXP 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of FDXR mRNA] CTD PMID:31150632 Fdxr Rat tetrachloromethane decreases expression ISO Fdxr (Mus musculus) 6480464 Carbon Tetrachloride results in decreased expression of FDXR mRNA CTD PMID:31919559 Fdxr Rat tetrachloromethane decreases expression EXP 6480464 Carbon Tetrachloride results in decreased expression of FDXR mRNA CTD PMID:31150632 Fdxr Rat thapsigargin increases expression ISO FDXR (Homo sapiens) 6480464 Thapsigargin results in increased expression of FDXR mRNA CTD PMID:22378314 Fdxr Rat theophylline multiple interactions ISO FDXR (Homo sapiens) 6480464 [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of FDXR protein CTD PMID:18951874 Fdxr Rat trametinib multiple interactions ISO FDXR (Homo sapiens) 6480464 [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of FDXR mRNA CTD PMID:36139627 Fdxr Rat trichloroethene increases methylation EXP 6480464 Trichloroethylene results in increased methylation of FDXR gene CTD PMID:27618143 Fdxr Rat triptonide decreases expression ISO Fdxr (Mus musculus) 6480464 triptonide results in decreased expression of FDXR mRNA CTD PMID:33045310 Fdxr Rat trovafloxacin decreases expression ISO Fdxr (Mus musculus) 6480464 trovafloxacin results in decreased expression of FDXR mRNA CTD PMID:35537566 Fdxr Rat Tungsten carbide multiple interactions ISO FDXR (Homo sapiens) 6480464 [tungsten carbide co-treated with Cobalt] results in increased expression of FDXR mRNA CTD PMID:18078969 and PMID:23052192 Fdxr Rat tunicamycin increases expression ISO FDXR (Homo sapiens) 6480464 Tunicamycin results in increased expression of FDXR mRNA CTD PMID:22378314 Fdxr Rat urethane decreases expression ISO FDXR (Homo sapiens) 6480464 Urethane results in decreased expression of FDXR mRNA CTD PMID:28818685 Fdxr Rat valproic acid increases methylation ISO FDXR (Homo sapiens) 6480464 Valproic Acid results in increased methylation of FDXR gene CTD PMID:29154799 Fdxr Rat vinclozolin increases expression EXP 6480464 vinclozolin results in increased expression of FDXR mRNA CTD PMID:22570695 Fdxr Rat vorinostat increases expression ISO FDXR (Homo sapiens) 6480464 vorinostat results in increased expression of FDXR mRNA CTD PMID:27188386 Fdxr Rat zidovudine multiple interactions ISO Fdxr (Mus musculus) 6480464 [Zidovudine co-treated with Lamivudine] results in increased expression of FDXR mRNA CTD PMID:18313992
(+)-schisandrin B (EXP) (-)-demecolcine (ISO) (1->4)-beta-D-glucan (ISO) (S)-colchicine (ISO) 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane (EXP) 1,2-dimethylhydrazine (ISO) 17alpha-ethynylestradiol (EXP,ISO) 17beta-estradiol (ISO) 2,2',4,4'-Tetrabromodiphenyl ether (ISO) 2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO) 2,4-dinitrotoluene (EXP) 2,6-dimethoxyphenol (ISO) 3,3',4,4',5-pentachlorobiphenyl (EXP) 3-chloropropane-1,2-diol (EXP) 3-methylcholanthrene (ISO) 4,4'-diaminodiphenylmethane (ISO) 4,4'-sulfonyldiphenol (ISO) 4-amino-2,6-dinitrotoluene (EXP) 5-fluorouracil (ISO) 8-Br-cAMP (ISO) acetamide (EXP) actinomycin D (ISO) adenine (ISO) aflatoxin B1 (ISO) alpha-Zearalanol (EXP) ammonium chloride (EXP) aristolochic acid A (ISO) arsane (ISO) arsenic atom (ISO) atrazine (ISO) benzene-1,2,4-triol (ISO) benzo[a]pyrene (ISO) benzo[a]pyrene diol epoxide I (ISO) beta-lapachone (ISO) bis(2-chloroethyl) sulfide (ISO) bis(2-ethylhexyl) phthalate (ISO) bisphenol A (EXP,ISO) Bisphenol B (ISO) bisphenol F (ISO) Brodifacoum (EXP) cadmium dichloride (ISO) camptothecin (ISO) carbamazepine (ISO) carbon nanotube (ISO) chlorohydrocarbon (ISO) chromium(6+) (ISO) cisplatin (ISO) clofibrate (ISO) cobalt atom (ISO) cobalt dichloride (ISO) cyclosporin A (ISO) daunorubicin (ISO) DDE (ISO) dextran sulfate (ISO) Dibutyl phosphate (ISO) dibutyl phthalate (EXP,ISO) disodium selenite (ISO) dorsomorphin (ISO) doxorubicin (ISO) entinostat (ISO) ethyl methanesulfonate (ISO) etoposide (ISO) flavonoids (EXP) flutamide (EXP) folic acid (ISO) formaldehyde (ISO) FR900359 (ISO) furfural (ISO) glafenine (EXP) hydrogen peroxide (ISO) indometacin (EXP) ivermectin (ISO) L-ascorbic acid (EXP) lamivudine (ISO) lipopolysaccharide (ISO) manganese atom (ISO) manganese(0) (ISO) manganese(II) chloride (ISO) menadione (ISO) methyl methanesulfonate (ISO) mono(2-ethylhexyl) phthalate (ISO) N-methyl-4-phenylpyridinium (ISO) Nutlin-3 (ISO) ozone (EXP) paracetamol (ISO) perfluorooctane-1-sulfonic acid (ISO) perfluorooctanoic acid (EXP) pifithrin-alpha hydrobromide (ISO) piroxicam (ISO) potassium dichromate (ISO) propanal (ISO) quercetin (ISO) resveratrol (ISO) SB 431542 (ISO) sodium arsenite (EXP,ISO) sodium chloride (ISO) sodium fluoride (ISO) sotorasib (ISO) tert-butyl hydroperoxide (ISO) tetrachloroethene (ISO) tetrachloromethane (EXP,ISO) thapsigargin (ISO) theophylline (ISO) trametinib (ISO) trichloroethene (EXP) triptonide (ISO) trovafloxacin (ISO) Tungsten carbide (ISO) tunicamycin (ISO) urethane (ISO) valproic acid (ISO) vinclozolin (EXP) vorinostat (ISO) zidovudine (ISO)
1.
Assessment of gene expression profiles in peripheral occlusive arterial disease.
Bubenek S, etal., Can J Cardiol. 2012 Nov-Dec;28(6):712-20. doi: 10.1016/j.cjca.2012.03.013. Epub 2012 Jun 19.
2.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.
Rat ISS GO annotations from GOA human gene data--August 2006
GOA data from the GO Consortium
4.
Induction and mitochondrial localization of cytochrome P450scc system enzymes in normal and transformed ovarian granulosa cells.
Hanukoglu I, etal., J Cell Biol. 1990 Oct;111(4):1373-81.
5.
Iron-sulfur cluster biogenesis in mammalian cells: New insights into the molecular mechanisms of cluster delivery.
Maio N and Rouault TA, Biochim Biophys Acta. 2015 Jun;1853(6):1493-512. doi: 10.1016/j.bbamcr.2014.09.009. Epub 2014 Sep 19.
6.
Differential capacity for cholesterol transport and processing in large and small rat luteal cells.
McLean MP, etal., Endocrinology. 1992 Nov;131(5):2203-12.
7.
Rat ISS GO annotations from MGI mouse gene data--August 2006
MGD data from the GO Consortium
8.
Androgen synthesis in adrenarche.
Miller WL Rev Endocr Metab Disord. 2009 Mar;10(1):3-17.
9.
Electronic Transfer of LocusLink and RefSeq Data
NCBI rat LocusLink and RefSeq merged data July 26, 2002
10.
GOA pipeline
RGD automated data pipeline
11.
Data Import for Chemical-Gene Interactions
RGD automated import pipeline for gene-chemical interactions
12.
cDNA cloning, overproduction and characterization of rat adrenodoxin reductase.
Sagara Y, etal., Biochim Biophys Acta 1999 Oct 12;1434(2):284-95.
Fdxr Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 10 101,006,845 - 101,015,582 (-) NCBI GRCr8 mRatBN7.2 10 100,507,863 - 100,516,649 (-) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 10 100,507,865 - 100,516,658 (-) Ensembl mRatBN7.2 Ensembl UTH_Rnor_SHR_Utx 10 105,568,049 - 105,576,738 (-) NCBI Rnor_SHR UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 10 105,031,109 - 105,039,798 (-) NCBI Rnor_SHRSP UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 10 100,428,857 - 100,437,546 (-) NCBI Rnor_WKY UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 10 103,817,724 - 103,826,413 (-) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 10 103,817,704 - 103,826,448 (-) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 10 104,468,590 - 104,477,279 (+) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 10 105,342,684 - 105,351,374 (-) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 RGSC_v3.1 10 105,357,187 - 105,365,878 (-) NCBI Celera 10 99,084,255 - 99,092,947 (-) NCBI Celera Cytogenetic Map 10 q32.1 NCBI
FDXR Human Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCh38 17 74,862,497 - 74,872,994 (-) NCBI GRCh38 GRCh38 hg38 GRCh38 GRCh38.p14 Ensembl 17 74,862,497 - 74,873,031 (-) Ensembl GRCh38 hg38 GRCh38 GRCh37 17 72,858,619 - 72,869,119 (-) NCBI GRCh37 GRCh37 hg19 GRCh37 Build 36 17 70,370,214 - 70,380,751 (-) NCBI NCBI36 Build 36 hg18 NCBI36 Build 34 17 70,370,220 - 70,380,692 NCBI Celera 17 69,451,871 - 69,462,405 (-) NCBI Celera Cytogenetic Map 17 q25.1 NCBI HuRef 17 68,269,147 - 68,279,670 (-) NCBI HuRef CHM1_1 17 72,923,450 - 72,933,984 (-) NCBI CHM1_1 T2T-CHM13v2.0 17 75,754,283 - 75,764,782 (-) NCBI T2T-CHM13v2.0
Fdxr Mouse Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCm39 11 115,158,850 - 115,167,925 (-) NCBI GRCm39 GRCm39 mm39 GRCm39 Ensembl 11 115,158,850 - 115,167,876 (-) Ensembl GRCm39 Ensembl GRCm38 11 115,268,024 - 115,277,101 (-) NCBI GRCm38 GRCm38 mm10 GRCm38 GRCm38.p6 Ensembl 11 115,268,024 - 115,277,050 (-) Ensembl GRCm38 mm10 GRCm38 MGSCv37 11 115,129,339 - 115,138,283 (-) NCBI GRCm37 MGSCv37 mm9 NCBIm37 MGSCv36 11 115,084,115 - 115,093,059 (-) NCBI MGSCv36 mm8 Celera 11 127,033,656 - 127,042,608 (-) NCBI Celera Cytogenetic Map 11 E2 NCBI cM Map 11 80.84 NCBI
Fdxr Chinchilla Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChiLan1.0 Ensembl NW_004955553 1,746,670 - 1,755,315 (-) Ensembl ChiLan1.0 ChiLan1.0 NW_004955553 1,746,759 - 1,755,316 (-) NCBI ChiLan1.0 ChiLan1.0
FDXR Bonobo Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl NHGRI_mPanPan1-v2 19 90,899,791 - 90,910,451 (-) NCBI NHGRI_mPanPan1-v2 NHGRI_mPanPan1 17 95,722,695 - 95,733,347 (-) NCBI NHGRI_mPanPan1 Mhudiblu_PPA_v0 17 68,808,123 - 68,818,642 (-) NCBI Mhudiblu_PPA_v0 Mhudiblu_PPA_v0 panPan3 PanPan1.1 17 74,364,343 - 74,374,852 (-) NCBI panpan1.1 PanPan1.1 panPan2 PanPan1.1 Ensembl 17 74,364,343 - 74,374,852 (-) Ensembl panpan1.1 panPan2
FDXR Dog Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl CanFam3.1 9 5,567,411 - 5,577,427 (+) NCBI CanFam3.1 CanFam3.1 canFam3 CanFam3.1 CanFam3.1 Ensembl 9 5,567,328 - 5,577,277 (+) Ensembl CanFam3.1 canFam3 CanFam3.1 Dog10K_Boxer_Tasha 9 6,246,975 - 6,256,975 (+) NCBI Dog10K_Boxer_Tasha ROS_Cfam_1.0 9 6,239,485 - 6,249,477 (+) NCBI ROS_Cfam_1.0 ROS_Cfam_1.0 Ensembl 9 6,239,458 - 6,249,473 (+) Ensembl ROS_Cfam_1.0 Ensembl UMICH_Zoey_3.1 9 6,276,453 - 6,286,449 (+) NCBI UMICH_Zoey_3.1 UNSW_CanFamBas_1.0 9 6,387,040 - 6,397,024 (+) NCBI UNSW_CanFamBas_1.0 UU_Cfam_GSD_1.0 9 6,447,362 - 6,457,354 (+) NCBI UU_Cfam_GSD_1.0
Fdxr
FDXR Pig Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl Sscrofa11.1 Ensembl 12 6,372,009 - 6,382,769 (+) Ensembl Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa11.1 12 6,372,224 - 6,382,769 (+) NCBI Sscrofa11.1 Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa10.2 12 6,362,701 - 6,373,244 (+) NCBI Sscrofa10.2 Sscrofa10.2 susScr3 Pig Cytomap 12 p NCBI
FDXR Green Monkey Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChlSab1.1 16 46,785,669 - 46,796,154 (+) NCBI ChlSab1.1 ChlSab1.1 chlSab2 ChlSab1.1 Ensembl 16 46,785,591 - 46,796,187 (+) Ensembl ChlSab1.1 ChlSab1.1 Ensembl chlSab2 Vero_WHO_p1.0 NW_023666077 17,571,055 - 17,581,546 (+) NCBI Vero_WHO_p1.0 Vero_WHO_p1.0
Fdxr
.
Predicted Target Of
Count of predictions: 138 Count of miRNA genes: 106 Interacting mature miRNAs: 112 Transcripts: ENSRNOT00000004592 Prediction methods: Microtar, Miranda, Rnahybrid Result types: miRGate_prediction
1354641 Bvd2 Brain ventricular dilatation QTL 2 6.36 0.001 brain ventricle morphology trait (VT:0000822) hydrocephalus severity score (CMO:0001881) 10 93223816 107057807 Rat 61449 Ciaa2 CIA Autoantibody QTL 2 7.1 blood autoantibody amount (VT:0003725) calculated serum anti-type 2 collagen antibody titer (CMO:0001279) 10 63221094 107211142 Rat 61325 Aia5 Adjuvant induced arthritis QTL 5 0.01 joint integrity trait (VT:0010548) joint inflammation composite score (CMO:0000919) 10 23444813 104060283 Rat 1298078 Stresp5 Stress response QTL 5 2.99 0.00025 blood corticosterone amount (VT:0005345) plasma corticosterone level (CMO:0001173) 10 42045676 104670812 Rat 1549831 Bss6 Bone structure and strength QTL 6 4 lumbar vertebra strength trait (VT:0010574) vertebra ultimate force (CMO:0001678) 10 57576521 102576521 Rat 1579915 Bp280 Blood pressure QTL 280 0.001 arterial blood pressure trait (VT:2000000) mean arterial blood pressure (CMO:0000009) 10 90404397 107211142 Rat 2298548 Neuinf7 Neuroinflammation QTL 7 3.4 nervous system integrity trait (VT:0010566) spinal cord RT1-B protein level (CMO:0002132) 10 72224939 107211142 Rat 1302404 Cia27 Collagen induced arthritis QTL 27 2.6 0.0045 joint integrity trait (VT:0010548) experimental arthritis severity measurement (CMO:0001459) 10 76452683 107211142 Rat 2317754 Glom25 Glomerulus QTL 25 3.5 urine protein amount (VT:0005160) urine protein level (CMO:0000591) 10 82685200 107211142 Rat 70168 Eae12 Experimental allergic encephalomyelitis QTL 12 0.0009 nervous system integrity trait (VT:0010566) experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046) 10 92238497 101012337 Rat 70171 Cari1 Carrageenan-induced inflammation QTL 1 4.9 0.0005 hypodermis integrity trait (VT:0010550) inflammatory exudate volume (CMO:0001429) 10 53797385 107211142 Rat 10450493 Bp382 Blood pressure QTL 382 0.002 arterial blood pressure trait (VT:2000000) mean arterial blood pressure (CMO:0000009) 10 94759759 107211142 Rat 1578672 Bmd16 Bone mineral density QTL 16 6.2 femur mineral mass (VT:0010011) compact volumetric bone mineral density (CMO:0001730) 10 96703043 107057807 Rat 61354 Pia10 Pristane induced arthritis QTL 10 0.01 joint integrity trait (VT:0010548) joint inflammation composite score (CMO:0000919) 10 23444813 104060283 Rat 2313103 Bss80 Bone structure and strength QTL 80 2 0.0001 tibia strength trait (VT:1000284) tibia midshaft endosteal cross-sectional area (CMO:0001716) 10 62057807 107057807 Rat 2293646 Bss25 Bone structure and strength QTL 25 10.96 0.0001 femur morphology trait (VT:0000559) femur cross-sectional area (CMO:0001661) 10 69738412 107211142 Rat 2303118 Mamtr7 Mammary tumor resistance QTL 7 0.003 mammary gland integrity trait (VT:0010552) mammary tumor growth rate (CMO:0000344) 10 9658275 104670812 Rat 2300172 Bmd57 Bone mineral density QTL 57 9.8 0.0001 femur mineral mass (VT:0010011) volumetric bone mineral density (CMO:0001553) 10 69738412 107211142 Rat 70193 Mcs7 Mammary carcinoma susceptibility QTL 7 2.38 mammary gland integrity trait (VT:0010552) mammary tumor number (CMO:0000343) 10 72224939 107211142 Rat 2313105 Bss79 Bone structure and strength QTL 79 1.8 0.0001 tibia size trait (VT:0100001) tibia midshaft cross-sectional area (CMO:0001717) 10 62057807 107057807 Rat 61363 Oia3 Oil induced arthritis QTL 3 0.001 joint integrity trait (VT:0010548) joint inflammation composite score (CMO:0000919) 10 87307617 107211142 Rat 2316949 Gluco60 Glucose level QTL 60 3.7 blood glucose amount (VT:0000188) blood glucose level (CMO:0000046) 10 14487011 107057807 Rat 724530 Bp149 Blood pressure QTL 149 0.0001 arterial blood pressure trait (VT:2000000) mean arterial blood pressure (CMO:0000009) 10 90627439 107211142 Rat 1300137 Bp186 Blood pressure QTL 186 3.57 arterial blood pressure trait (VT:2000000) blood pressure time series experimental set point of the baroreceptor response (CMO:0002593) 10 90627439 107057807 Rat 2293663 Bss33 Bone structure and strength QTL 33 9.34 0.0001 femur strength trait (VT:0010010) femur midshaft polar moment of inertia (CMO:0001669) 10 69738412 107211142 Rat 1578663 Bss18 Bone structure and strength QTL 18 3.6 femur width (VT:1000666) femoral neck width (CMO:0001695) 10 96703043 107057807 Rat 7387312 Bw125 Body weight QTL 125 3 0.0047 retroperitoneal fat pad mass (VT:0010430) retroperitoneal fat pad weight (CMO:0000356) 10 64890616 107211142 Rat 2312672 Insul15 Insulin level QTL 15 0.01 blood insulin amount (VT:0001560) serum insulin level (CMO:0000358) 10 57134272 102134272 Rat 6893357 Bw102 Body weight QTL 102 0.5 0.36 body mass (VT:0001259) body weight (CMO:0000012) 10 80515287 101325465 Rat 12880384 Cm107 Cardiac mass QTL 107 0.001 heart mass (VT:0007028) heart wet weight to body weight ratio (CMO:0002408) 90404397 107211142 Rat 12880385 Cm108 Cardiac mass QTL 108 0.001 heart left ventricle mass (VT:0007031) heart left ventricle weight to body weight ratio (CMO:0000530) 90404397 107211142 Rat 2317029 Aia19 Adjuvant induced arthritis QTL 19 2.98 joint integrity trait (VT:0010548) left rear ankle joint diameter (CMO:0002149) 10 66978955 107211142 Rat 2303589 Bw87 Body weight QTL 87 2 body mass (VT:0001259) body weight (CMO:0000012) 10 81285008 107211142 Rat 12880396 Am13 Aortic mass QTL 13 0.001 aorta mass (VT:0002845) aorta weight to aorta length to body weight ratio (CMO:0002722) 10 90404397 107211142 Rat 12880398 Kidm67 Kidney mass QTL 67 0.001 kidney mass (VT:0002707) both kidneys wet weight to body weight ratio (CMO:0000340) 10 90404397 107211142 Rat 61387 Bp1 Blood pressure QTL 1 5.1 arterial blood pressure trait (VT:2000000) diastolic blood pressure (CMO:0000005) 10 51770177 107211142 Rat 2317039 Aia6 Adjuvant induced arthritis QTL 6 4.31 joint integrity trait (VT:0010548) right rear ankle joint diameter (CMO:0002150) 10 66978955 107211142 Rat 12880395 Cm109 Cardiac mass QTL 109 0.001 heart right ventricle mass (VT:0007033) heart right ventricle weight to body weight ratio (CMO:0000914) 10 90404397 107211142 Rat 61396 Bp9 Blood pressure QTL 9 4.8 0.0001 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 10 68420376 107211142 Rat 634320 Niddm49 Non-insulin dependent diabetes mellitus QTL 49 4.41 blood glucose amount (VT:0000188) plasma glucose level (CMO:0000042) 10 88539139 107211142 Rat 1331791 Cm31 Cardiac mass QTL 31 3.84606 heart mass (VT:0007028) heart wet weight (CMO:0000069) 10 29299504 107211142 Rat 10450498 Bp384 Blood pressure QTL 384 0.002 arterial blood pressure trait (VT:2000000) mean arterial blood pressure (CMO:0000009) 10 67750049 107211142 Rat 4889492 Pancm2 Pancreatic morphology QTL 2 3.2 pancreatic beta cell morphology trait (VT:0005217) ratio of insulin-positive cell area to total area of splenic region of pancreas (CMO:0001814) 10 76748906 107211142 Rat 6893366 Bw106 Body weight QTL 106 0.3 0.47 body mass (VT:0001259) body weight (CMO:0000012) 10 70199100 107211142 Rat 2293698 Bss43 Bone structure and strength QTL 43 5.33 0.0001 lumbar vertebra size trait (VT:0010518) lumbar vertebra cross-sectional area (CMO:0001689) 10 59209888 104209888 Rat 1576313 Pia25 Pristane induced arthritis QTL 25 joint integrity trait (VT:0010548) joint inflammation composite score (CMO:0000919) 10 96120911 104060283 Rat 631267 Cia20 Collagen induced arthritis QTL 20 3.2 joint integrity trait (VT:0010548) joint inflammation composite score (CMO:0000919) 10 23444813 104060283 Rat 1576307 Cia28 Collagen induced arthritis QTL 28 joint integrity trait (VT:0010548) joint inflammation composite score (CMO:0000919) 10 96120911 104060283 Rat 1576308 Schws1 Schwannoma susceptibility QTL 1 0.0041 nervous system integrity trait (VT:0010566) percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017) 10 40035094 102359817 Rat 631269 Cia22 Collagen induced arthritis QTL 22 8.9 joint integrity trait (VT:0010548) joint inflammation composite score (CMO:0000919) 10 40035094 104060283 Rat 631268 Cia21 Collagen induced arthritis QTL 21 3.1 joint integrity trait (VT:0010548) joint inflammation composite score (CMO:0000919) 10 14487011 104060283 Rat 631270 Cia23 Collagen induced arthritis QTL 23 3.9 joint integrity trait (VT:0010548) joint inflammation composite score (CMO:0000919) 10 40035094 104060283 Rat 2292438 Bp311 Blood pressure QTL 311 arterial blood pressure trait (VT:2000000) mean arterial blood pressure (CMO:0000009) 10 76246085 107211142 Rat 2312662 Slep8 Serum leptin concentration QTL 8 0.05 blood leptin amount (VT:0005667) serum leptin level (CMO:0000780) 10 57134272 102134272 Rat 2292436 Bp310 Blood pressure QTL 310 arterial blood pressure trait (VT:2000000) mean arterial blood pressure (CMO:0000009) 10 94759759 107211142 Rat 1600367 Mcs15 Mammary carcinoma susceptibility QTL 15 4.5 mammary gland integrity trait (VT:0010552) mammary tumor number (CMO:0000343) 10 85565469 103884409 Rat 631539 Oia6 Oil induced arthritis QTL 6 joint integrity trait (VT:0010548) joint inflammation composite score (CMO:0000919) 10 97010147 104670812 Rat 631538 Oia5 Oil induced arthritis QTL 5 joint integrity trait (VT:0010548) joint inflammation composite score (CMO:0000919) 10 87055121 107211142 Rat 61436 Cia5 Collagen induced arthritis QTL 5 4.9 joint integrity trait (VT:0010548) joint inflammation composite score (CMO:0000919) 10 91228102 104060283 Rat 1642980 Bp300 Blood pressure QTL 300 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 10 68383129 107211142 Rat 2312668 Scl65 Serum cholesterol level QTL 65 0.001 blood cholesterol amount (VT:0000180) serum total cholesterol level (CMO:0000363) 10 57134272 102134272 Rat
Click on a value in the shaded box below the category label to view a detailed expression data table for that system.
alimentary part of gastrointestinal system
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Ensembl Acc Id:
ENSRNOT00000085636 ⟹ ENSRNOP00000075248
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl 10 100,507,865 - 100,516,658 (-) Ensembl Rnor_6.0 Ensembl 10 103,817,704 - 103,826,448 (-) Ensembl
Ensembl Acc Id:
ENSRNOT00000103108 ⟹ ENSRNOP00000079013
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl 10 100,507,865 - 100,516,658 (-) Ensembl
RefSeq Acc Id:
NM_024153 ⟹ NP_077067
RefSeq Status:
PROVISIONAL
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 10 101,006,846 - 101,015,535 (-) NCBI mRatBN7.2 10 100,507,865 - 100,516,556 (-) NCBI Rnor_6.0 10 103,817,724 - 103,826,413 (-) NCBI Rnor_5.0 10 104,468,590 - 104,477,279 (+) NCBI RGSC_v3.4 10 105,342,684 - 105,351,374 (-) RGD Celera 10 99,084,255 - 99,092,947 (-) RGD
Sequence:
CGGCGGGTTGCTCTTCTCAGCCATGGCTCCTCGCTGCTGGCGCTGGTGGAGCTGGTCCGCGTGGCCTGGGGTTCGGCCGCTTCCCTCCAGGAGCACTCCGACCCCTGGCTTCTGCAAGAAGTTCTCCA
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RefSeq Acc Id:
XM_039086911 ⟹ XP_038942839
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 10 101,006,845 - 101,015,582 (-) NCBI mRatBN7.2 10 100,507,863 - 100,516,449 (-) NCBI
RefSeq Acc Id:
NP_077067 ⟸ NM_024153
- Peptide Label:
precursor
- UniProtKB:
P56522 (UniProtKB/Swiss-Prot), A6HKL4 (UniProtKB/TrEMBL), A0A8I6G2P7 (UniProtKB/TrEMBL)
- Sequence:
MAPRCWRWWSWSAWPGVRPLPSRSTPTPGFCKKFSTQETTPQICVVGSGPAGFYTAQHLLKHHTRAHVDIYEKQLVPFGLVRFGVAPDHPEVKNVINTFTQTARSDRCAFRGNVVVGRDVSVPELREA
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Ensembl Acc Id:
ENSRNOP00000075248 ⟸ ENSRNOT00000085636
RefSeq Acc Id:
XP_038942839 ⟸ XM_039086911
- Peptide Label:
isoform X1
Ensembl Acc Id:
ENSRNOP00000079013 ⟸ ENSRNOT00000103108
RGD ID: 13697881 Promoter ID: EPDNEW_R8406 Type: initiation region Name: Fdxr_1 Description: ferredoxin reductase SO ACC ID: SO:0000170 Source: EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/ ) Experiment Methods: Single-end sequencing. Position: Rat Assembly Chr Position (strand) Source Rnor_6.0 10 103,826,465 - 103,826,525 EPDNEW
Date
Current Symbol
Current Name
Previous Symbol
Previous Name
Description
Reference
Status
2004-09-10
Fdxr
ferredoxin reductase
adrenodoxin reductase
Name updated
1299863 APPROVED
2002-08-07
Fdxr
adrenodoxin reductase
Symbol and Name status set to provisional
70820 PROVISIONAL
Note Type
Note
Reference
gene_physical_interaction
binds to adrenodoxin (Ad) by ionic interaction
727285
