Gene: Rhbdf2 (rhomboid 5 homolog 2) Rattus norvegicus
Symbol: Rhbdf2
Name: rhomboid 5 homolog 2
Description: INVOLVED IN negative regulation of protein secretion (ortholog); ASSOCIATED WITH Keratosis Palmoplantaris with Esophageal Cancer (ortholog); nonepidermolytic palmoplantar keratoderma (ortholog); FOUND IN endoplasmic reticulum membrane (ortholog); plasma membrane (ortholog); INTERACTS WITH 2,2',5,5'-tetrachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: inactive rhomboid protein 2; LOC303690; Rhbdl6; rhomboid 5 homolog 2 (Drosophila); rhomboid family member 2; rhomboid, veinlet-like 6; rhomboid, veinlet-like 6 (Drosophila)
Homo sapiens (human) : RHBDF2 (rhomboid 5 homolog 2)  HGNC  Alliance
Mus musculus (house mouse) : Rhbdf2 (rhomboid 5 homolog 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rhbdf2 (rhomboid 5 homolog 2)
Pan paniscus (bonobo/pygmy chimpanzee) : RHBDF2 (rhomboid 5 homolog 2)
Canis lupus familiaris (dog) : RHBDF2 (rhomboid 5 homolog 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rhbdf2 (rhomboid 5 homolog 2)
Sus scrofa (pig) : RHBDF2 (rhomboid 5 homolog 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.010105,573,759 - 105,600,885 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.010105,236,674 - 105,263,865 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.410106,715,043 - 106,742,198 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.110106,730,311 - 106,738,841 (-)NCBI
Celera10100,405,281 - 100,431,892 (-)NCBICelera
Cytogenetic Map10q32.2NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Rhbdf2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1309699
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-01-30
Status: ACTIVE