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Gene: Acox1 (acyl-CoA oxidase 1) Rattus norvegicus
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Symbol: Acox1
Name: acyl-CoA oxidase 1
Description: Exhibits anion binding activity; palmitoyl-CoA oxidase activity; and protein homodimerization activity. Involved in fatty acid beta-oxidation using acyl-CoA oxidase. Localizes to the peroxisome. Human ortholog(s) of this gene implicated in peroxisomal acyl-CoA oxidase deficiency. Orthologous to human ACOX1 (acyl-CoA oxidase 1); PARTICIPATES IN alpha-linoleic acid metabolic pathway; eicosanoid signaling pathway via peroxisome proliferator-activated receptor gamma; fatty acid metabolic pathway; INTERACTS WITH (R)-lipoic acid; (RS)-amphetamine; 1-naphthyl isothiocyanate.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: aCoA; acyl-coA oxidase; acyl-CoA oxidase 1, palmitoyl; acyl-Coenzyme A oxidase 1; acyl-Coenzyme A oxidase 1, palmitoyl; AOX; palmitoyl-CoA oxidase; peroxisomal acyl-coenzyme A oxidase 1; RATACOA1
Orthologs:
Homo sapiens (human) : ACOX1 (acyl-CoA oxidase 1)  HGNC  Alliance
Mus musculus (house mouse) : Acox1 (acyl-Coenzyme A oxidase 1, palmitoyl)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Acox1 (acyl-CoA oxidase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : ACOX1 (acyl-CoA oxidase 1)
Canis lupus familiaris (dog) : ACOX1 (acyl-CoA oxidase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Acox1 (acyl-CoA oxidase 1)
Sus scrofa (pig) : ACOX1 (acyl-CoA oxidase 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.010104,724,534 - 104,748,003 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.010103,537,761 - 103,561,087 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.410106,281,977 - 106,319,382 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.110106,294,947 - 106,310,607 (-)NCBI
Celera1099,981,033 - 100,004,515 (-)NCBICelera
Cytogenetic Map10q32.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Acox1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 619757
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-06-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.