Nptx1 (neuronal pentraxin 1) - Rat Genome Database

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Gene: Nptx1 (neuronal pentraxin 1) Rattus norvegicus
Analyze
Symbol: Nptx1
Name: neuronal pentraxin 1
RGD ID: 628894
Description: Predicted to enable metal ion binding activity. Involved in several processes, including mitochondrial fragmentation involved in apoptotic process; neurotransmitter receptor localization to postsynaptic specialization membrane; and postsynaptic density assembly. Is active in glutamatergic synapse and synaptic cleft. Human ortholog(s) of this gene implicated in autosomal dominant cerebellar ataxia. Orthologous to human NPTX1 (neuronal pentraxin 1); INTERACTS WITH (S)-colchicine; 1,2,4-trimethylbenzene; 1,3,5-trinitro-1,3,5-triazinane.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 47 kDa taipoxin-binding protein; LOC360249; neuronal pentraxin I; neuronal pentraxin-1; NP-I; NP1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr810105,309,578 - 105,318,829 (-)NCBIGRCr8
mRatBN7.210104,811,107 - 104,820,358 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl10104,811,403 - 104,820,367 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx10109,914,282 - 109,923,567 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.010109,377,316 - 109,386,601 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.010104,731,702 - 104,740,953 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.010108,682,637 - 108,691,592 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl10108,682,638 - 108,691,367 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.010108,286,989 - 108,295,944 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.410108,918,661 - 108,927,616 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera10103,356,568 - 103,365,489 (-)NCBICelera
Cytogenetic Map10q32.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Nptx1Ratgenetic disease  ISONPTX1 (Homo sapiens)8554872ClinVar Annotator: match by term: Inborn genetic diseasesClinVarPMID:25741868 more ...
Nptx1RatSpinocerebellar Ataxia 50  ISONPTX1 (Homo sapiens)8554872ClinVar Annotator: match by term: Spinocerebellar ataxia 50ClinVarPMID:25741868 more ...
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Nptx1RatSpinocerebellar Ataxia 50  ISONPTX1 (Homo sapiens)7240710 OMIM 

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Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Nptx1Rat(S)-colchicine increases expressionEXP 6480464Colchicine results in increased expression of NPTX1 mRNACTDPMID:18255150
Nptx1Rat1,2,4-trimethylbenzene increases expressionEXP 6480464pseudocumene results in increased expression of NPTX1 proteinCTDPMID:17337753
Nptx1Rat1,3,5-trinitro-1,3,5-triazinane decreases expressionEXP 6480464cyclonite results in decreased expression of NPTX1 mRNACTDPMID:25559034
Nptx1Rat17beta-estradiol increases expressionISONPTX1 (Homo sapiens)6480464Estradiol results in increased expression of NPTX1 mRNACTDPMID:31614463
Nptx1Rat2,2',4,4',5,5'-hexachlorobiphenyl multiple interactionsISONptx1 (Mus musculus)6480464[2 more ...CTDPMID:25510870
Nptx1Rat2,2',5,5'-tetrachlorobiphenyl multiple interactionsISONptx1 (Mus musculus)6480464[2 more ...CTDPMID:25510870
Nptx1Rat2,2',5,5'-tetrachlorobiphenyl decreases expressionISONPTX1 (Homo sapiens)64804642 more ...CTDPMID:36804509
Nptx1Rat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISONptx1 (Mus musculus)6480464[TIPARP gene mutant form results in increased susceptibility to Tetrachlorodibenzodioxin] which results in increased expression of NPTX1 mRNA and AHR protein affects the reaction [Tetrachlorodibenzodioxin results in increased expression of NPTX1 mRNA]CTDPMID:16214954 and PMID:25975270
Nptx1Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionISONptx1 (Mus musculus)6480464Tetrachlorodibenzodioxin results in increased expression of NPTX1 mRNACTDPMID:16214954 more ...
Nptx1Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISONptx1 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of NPTX1 mRNACTDPMID:26377647
Nptx1Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionISONPTX1 (Homo sapiens)6480464Tetrachlorodibenzodioxin results in increased expression of NPTX1 mRNACTDPMID:22262711 and PMID:25445724
Nptx1Rat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISONPTX1 (Homo sapiens)6480464AHR gene SNP affects the reaction [Tetrachlorodibenzodioxin results in increased expression of NPTX1 mRNA]CTDPMID:25445724
Nptx1Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of NPTX1 mRNACTDPMID:22808131 more ...
Nptx1Rat2,3,7,8-Tetrachlorodibenzofuran decreases expressionEXP 64804642 more ...CTDPMID:32109520
Nptx1Rat2,4-dibromophenyl 2,4,5-tribromophenyl ether increases expressionISONPTX1 (Homo sapiens)64804642 more ...CTDPMID:26705709
Nptx1Rat3,3',4,4',5-pentachlorobiphenyl increases expressionISONPTX1 (Homo sapiens)64804643 more ...CTDPMID:22262711
Nptx1Rat3,3',5,5'-tetrabromobisphenol A decreases expressionISONPTX1 (Homo sapiens)6480464tetrabromobisphenol A results in decreased expression of NPTX1 mRNACTDPMID:33476716
Nptx1Rat4,4'-sulfonyldiphenol increases expressionISONptx1 (Mus musculus)6480464bisphenol S results in increased expression of NPTX1 mRNACTDPMID:30951980
Nptx1Rat4,4'-sulfonyldiphenol affects methylationISONptx1 (Mus musculus)6480464bisphenol S affects the methylation of NPTX1 geneCTDPMID:31683443
Nptx1Rat5-aza-2'-deoxycytidine affects expressionISONPTX1 (Homo sapiens)6480464Decitabine affects the expression of NPTX1 mRNACTDPMID:23300844

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Biological Process
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Cellular Component
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Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Nptx1Ratcytoplasmic vesicle located_inIEAUniProtKB-KW:KW-09681600115GO_REF:0000043UniProtGO_REF:0000043
Nptx1Ratendoplasmic reticulum located_inIEAUniProtKB-SubCell:SL-00951600115GO_REF:0000044UniProtGO_REF:0000044
Nptx1Ratendoplasmic reticulum located_inIEAUniProtKB-KW:KW-02561600115GO_REF:0000043UniProtGO_REF:0000043
Nptx1Ratextracellular region located_inIEAUniProtKB-SubCell:SL-02431600115GO_REF:0000044UniProtGO_REF:0000044
Nptx1Ratextracellular region located_inIEAUniProtKB-KW:KW-09641600115GO_REF:0000043UniProtGO_REF:0000043
Nptx1Ratglutamatergic synapse is_active_inIMP 13702141PMID:29024665SynGO 
Nptx1Ratglutamatergic synapse is_active_inIEAUniProtKB:Q15818 and ensembl:ENSP000003075491600115GO_REF:0000107EnsemblGO_REF:0000107
Nptx1Ratglutamatergic synapse is_active_inIDA 13702141PMID:29024665SynGO 
Nptx1Ratglutamatergic synapse is_active_inISONPTX1 (Homo sapiens)1624291 PMID:27986928RGDPMID:27986928
Nptx1Ratglutamatergic synapse is_active_inEXP 13702141PMID:29024665SynGO 
Nptx1Ratsynaptic cleft is_active_inIDA 13702141PMID:29024665SynGO 
Nptx1Rattransport vesicle located_inIEAUniProtKB-SubCell:SL-02441600115GO_REF:0000044UniProtGO_REF:0000044
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Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Nptx1Ratmetal ion binding enablesIEAUniProtKB-KW:KW-04791600115GO_REF:0000043UniProtGO_REF:0000043


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#
Reference Title
Reference Citation
1. NP1 regulates neuronal activity-dependent accumulation of BAX in mitochondria and mitochondrial dynamics. Clayton KB, etal., J Neurosci. 2012 Jan 25;32(4):1453-66.
2. Astrocyte-Secreted Glypican 4 Regulates Release of Neuronal Pentraxin 1 from Axons to Induce Functional Synapse Formation. Farhy-Tselnicker I, etal., Neuron. 2017 Oct 11;96(2):428-445.e13. doi: 10.1016/j.neuron.2017.09.053.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. GOA pipeline RGD automated data pipeline
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Neuronal pentraxin, a secreted protein with homology to acute phase proteins of the immune system. Schlimgen AK, etal., Neuron 1995 Mar;14(3):519-26.
9. Modulation of Neuronal Pentraxin 1 Expression in Rat Pancreatic beta-Cells Submitted to Chronic Glucotoxic Stress. Schvartz D, etal., Mol Cell Proteomics. 2012 Aug;11(8):244-54. Epub 2012 Mar 16.
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PMID:10748068   PMID:15115814   PMID:16763034   PMID:22956834   PMID:27986928   PMID:32357304   PMID:34142698  



Nptx1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr810105,309,578 - 105,318,829 (-)NCBIGRCr8
mRatBN7.210104,811,107 - 104,820,358 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl10104,811,403 - 104,820,367 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx10109,914,282 - 109,923,567 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.010109,377,316 - 109,386,601 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.010104,731,702 - 104,740,953 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.010108,682,637 - 108,691,592 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl10108,682,638 - 108,691,367 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.010108,286,989 - 108,295,944 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.410108,918,661 - 108,927,616 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera10103,356,568 - 103,365,489 (-)NCBICelera
Cytogenetic Map10q32.3NCBI
NPTX1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381780,466,834 - 80,476,607 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1780,466,834 - 80,477,843 (-)EnsemblGRCh38hg38GRCh38
GRCh371778,440,634 - 78,450,407 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361776,055,228 - 76,064,999 (-)NCBINCBI36Build 36hg18NCBI36
Build 341776,055,227 - 76,064,999NCBI
Celera1775,069,005 - 75,078,529 (-)NCBICelera
Cytogenetic Map17q25.3NCBI
HuRef1773,878,650 - 73,888,424 (-)NCBIHuRef
CHM1_11778,526,902 - 78,536,673 (-)NCBICHM1_1
T2T-CHM13v2.01781,368,723 - 81,378,497 (-)NCBIT2T-CHM13v2.0
Nptx1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911119,429,545 - 119,438,646 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl11119,429,545 - 119,438,579 (-)EnsemblGRCm39 Ensembl
GRCm3811119,538,719 - 119,547,820 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11119,538,719 - 119,547,753 (-)EnsemblGRCm38mm10GRCm38
MGSCv3711119,400,033 - 119,409,134 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3611119,355,462 - 119,363,915 (-)NCBIMGSCv36mm8
Celera11131,286,494 - 131,295,595 (-)NCBICelera
Cytogenetic Map11E2NCBI
cM Map1183.95NCBI
Nptx1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555062,447,109 - 2,456,965 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555062,447,429 - 2,456,612 (+)NCBIChiLan1.0ChiLan1.0
NPTX1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21997,048,221 - 97,057,994 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan117101,948,062 - 101,957,835 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01774,896,150 - 74,905,917 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11780,629,443 - 80,638,376 (-)NCBIpanpan1.1PanPan1.1panPan2
NPTX1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.191,388,728 - 1,398,115 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl91,388,407 - 1,399,390 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha92,006,248 - 2,015,635 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.091,998,099 - 2,007,496 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl91,998,127 - 2,007,488 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.192,021,740 - 2,031,119 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.092,147,267 - 2,156,623 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.092,228,148 - 2,237,541 (+)NCBIUU_Cfam_GSD_1.0
Nptx1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244056022,027,566 - 2,038,459 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365944,373,473 - 4,384,461 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365944,373,500 - 4,384,394 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NPTX1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl122,036,810 - 2,046,193 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1122,036,727 - 2,046,202 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2121,938,606 - 1,948,101 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NPTX1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11672,438,728 - 72,449,205 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1672,439,482 - 72,449,139 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607743,751,846 - 43,761,582 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nptx1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248019,628,882 - 9,637,859 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248019,628,878 - 9,637,869 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Nptx1
24 total Variants

Predicted Target Of
Summary Value
Count of predictions:48
Count of miRNA genes:45
Interacting mature miRNAs:48
Transcripts:ENSRNOT00000005067
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 40 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
7387312Bw125Body weight QTL 12530.0047retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight (CMO:0000356)1064890616107211142Rat
12880384Cm107Cardiac mass QTL 1070.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)90404397107211142Rat
12880385Cm108Cardiac mass QTL 1080.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)90404397107211142Rat
1354641Bvd2Brain ventricular dilatation QTL 26.360.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)1093223816107057807Rat
2317029Aia19Adjuvant induced arthritis QTL 192.98joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)1066978955107211142Rat
2303589Bw87Body weight QTL 872body mass (VT:0001259)body weight (CMO:0000012)1081285008107211142Rat
12880396Am13Aortic mass QTL 130.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)1090404397107211142Rat
61449Ciaa2CIA Autoantibody QTL 27.1blood autoantibody amount (VT:0003725)calculated serum anti-type 2 collagen antibody titer (CMO:0001279)1063221094107211142Rat
12880398Kidm67Kidney mass QTL 670.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)1090404397107211142Rat
61387Bp1Blood pressure QTL 15.1arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)1051770177107211142Rat

1 to 10 of 40 rows
Nptx1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.210104,811,149 - 104,811,263 (+)MAPPERmRatBN7.2
Rnor_6.010108,682,384 - 108,682,497NCBIRnor6.0
Rnor_5.010108,286,736 - 108,286,849UniSTSRnor5.0
RGSC_v3.410108,918,408 - 108,918,521UniSTSRGSC3.4
Celera10103,356,315 - 103,356,428UniSTS
Cytogenetic Map10q32.3UniSTS
RH143293  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.210104,811,580 - 104,811,721 (+)MAPPERmRatBN7.2
Rnor_6.010108,682,815 - 108,682,955NCBIRnor6.0
Rnor_5.010108,287,167 - 108,287,307UniSTSRnor5.0
RGSC_v3.410108,918,839 - 108,918,979UniSTSRGSC3.4
Celera10103,356,746 - 103,356,886UniSTS
Cytogenetic Map10q32.3UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 45 113 62 61 30 25 30 6 185 93 93 45 60 31


RefSeq Transcripts NM_153735 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH473948 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000005067   ⟹   ENSRNOP00000005067
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl10104,811,403 - 104,820,367 (-)Ensembl
Rnor_6.0 Ensembl10108,682,638 - 108,691,367 (-)Ensembl
RefSeq Acc Id: NM_153735   ⟹   NP_714957
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr810105,309,578 - 105,318,829 (-)NCBI
mRatBN7.210104,811,107 - 104,820,358 (-)NCBI
Rnor_6.010108,682,637 - 108,691,592 (-)NCBI
Rnor_5.010108,286,989 - 108,295,944 (-)NCBI
RGSC_v3.410108,918,661 - 108,927,616 (-)RGD
Celera10103,356,568 - 103,365,489 (-)RGD
Sequence:
Protein RefSeqs NP_714957 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDM06797 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000005067
  ENSRNOP00000005067.6
GenBank Protein P47971 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_714957   ⟸   NM_153735
- Peptide Label: precursor
- UniProtKB: P47971 (UniProtKB/Swiss-Prot),   A6HL92 (UniProtKB/TrEMBL),   A0A0H2UHC1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000005067   ⟸   ENSRNOT00000005067
Pentraxin (PTX)

Name Modeler Protein Id AA Range Protein Structure
AF-P47971-F1-model_v2 AlphaFold P47971 1-432 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 24 of 24 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-22477 BioCyc
Ensembl Genes ENSRNOG00000003741 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000005067 ENTREZGENE
  ENSRNOT00000005067.7 UniProtKB/Swiss-Prot
Gene3D-CATH 2.60.120.200 UniProtKB/Swiss-Prot
InterPro ConA-like_dom_sf UniProtKB/Swiss-Prot
  Neuronal_Pentraxin_Related UniProtKB/Swiss-Prot
  Pentaxin_CS UniProtKB/Swiss-Prot
  Pentraxin-related UniProtKB/Swiss-Prot
KEGG Report rno:266777 UniProtKB/Swiss-Prot
NCBI Gene 266777 ENTREZGENE
PANTHER NEURONAL PENTRAXIN-1 UniProtKB/Swiss-Prot
  PENTRAXIN UniProtKB/Swiss-Prot
Pfam Pentaxin UniProtKB/Swiss-Prot
PhenoGen Nptx1 PhenoGen
PRINTS PENTAXIN UniProtKB/Swiss-Prot
PROSITE PTX_1 UniProtKB/Swiss-Prot
  PTX_2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000003741 RatGTEx
SMART PTX UniProtKB/Swiss-Prot
Superfamily-SCOP SSF49899 UniProtKB/Swiss-Prot
UniProt A0A0H2UHC1 ENTREZGENE, UniProtKB/TrEMBL
  A6HL92 ENTREZGENE, UniProtKB/TrEMBL
  NPTX1_RAT UniProtKB/Swiss-Prot, ENTREZGENE
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Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-03-22 Nptx1  neuronal pentraxin 1  Nptx1  neuronal pentraxin I  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-01-19 Nptx1  neuronal pentraxin I  Nptx1  neuronal pentraxin 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-02-23 Nptx1  neuronal pentraxin 1  Nptx1_predicted  neuronal pentraxin 1 (predicted)  Data merged from RGD:1310581 737654 APPROVED
2005-01-20 Nptx1  neuronal pentraxin 1      Symbol and Name status set to approved 1299863 APPROVED
2005-01-12 Nptx1_predicted  neuronal pentraxin 1 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL
2003-02-27 Nptx1  neuronal pentraxin 1      Symbol and Name status set to provisional 70820 PROVISIONAL

Note Type Note Reference
gene_expression expressed in neurons of cerebellum, hippocampus, and cerebral cortex 729007