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Gene: Pde6g (phosphodiesterase 6G) Rattus norvegicus
Symbol: Pde6g
Name: phosphodiesterase 6G
RGD ID: 1591130
Description: Exhibits spectrin binding activity. Predicted to be involved in activation of MAPK activity; positive regulation of G protein-coupled receptor signaling pathway; and positive regulation of epidermal growth factor receptor signaling pathway. Predicted to localize to photoreceptor outer segment membrane. Human ortholog(s) of this gene implicated in retinitis pigmentosa 57. Orthologous to human PDE6G (phosphodiesterase 6G); PARTICIPATES IN altered visual phototransduction pathway; retinitis pigmentosa pathway; visual phototransduction pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; aflatoxin B1 (ortholog).
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOC688297; phosphodiesterase 6G, cGMP-specific, rod, gamma; retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma; similar to Retinal rod rhodopsin-sensitive cGMP 3,5-cyclic phosphodiesterase gamma-subunit (GMP-PDE gamma)
Homo sapiens (human) : PDE6G (phosphodiesterase 6G)  HGNC  Alliance
Mus musculus (house mouse) : Pde6g (phosphodiesterase 6G, cGMP-specific, rod, gamma)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pde6g (phosphodiesterase 6G)
Pan paniscus (bonobo/pygmy chimpanzee) : PDE6G (phosphodiesterase 6G)
Canis lupus familiaris (dog) : PDE6G (phosphodiesterase 6G)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pde6g (phosphodiesterase 6G)
Sus scrofa (pig) : PDE6G (phosphodiesterase 6G)
Chlorocebus sabaeus (African green monkey) : PDE6G (phosphodiesterase 6G)
Heterocephalus glaber (naked mole-rat) : Pde6g (phosphodiesterase 6G)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.010109,620,499 - 109,625,214 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl10109,620,980 - 109,622,745 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.010109,214,063 - 109,219,693 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera10104,265,560 - 104,270,261 (-)NCBICelera
Cytogenetic Map10q32.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Pde6g
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1591130
Created: 2006-11-20
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.