Gene: Hgs (hepatocyte growth factor-regulated tyrosine kinase substrate) Rattus norvegicus
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Symbol: Hgs
Name: hepatocyte growth factor-regulated tyrosine kinase substrate
Description: ENCODES a protein that exhibits identical protein binding (ortholog); protein domain specific binding (ortholog); ubiquitin-dependent protein binding (ortholog); INVOLVED IN endosome to lysosome transport; membrane invagination (ortholog); negative regulation of angiogenesis (ortholog); PARTICIPATES IN autophagy pathway; vascular endothelial growth factor signaling pathway; endocytosis pathway; FOUND IN cytosol; membrane; secretory granule; INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; bisphenol A
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: HGF-regulated tyrosine kinase substrate; Hrs; SNAP-25-interacting protein Hrs-2
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.010109,638,944 - 109,657,460 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.010109,232,509 - 109,250,728 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.410109,861,289 - 109,869,587 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.110109,875,792 - 109,883,652 (+)NCBI
Celera10104,283,857 - 104,301,769 (+)NCBICelera
Cytogenetic Map10q32.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Hgs
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 69225
Created: 2001-11-14
Species: Rattus norvegicus
Last Modified: 2019-01-30
Status: ACTIVE