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Gene: Snap25 (synaptosome associated protein 25) Rattus norvegicus
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Symbol: Snap25
Name: synaptosome associated protein 25
Description: Exhibits several functions, including calcium-dependent protein binding activity; ion channel binding activity; and syntaxin-1 binding activity. Involved in several processes, including SNARE complex assembly; regulation of nervous system development; and signal release. Localizes to several cellular components, including the axonal growth cone; cytoplasm; and presynaptic membrane. Predicted to colocalize with the BLOC-1 complex and vesicle. Human ortholog(s) of this gene implicated in Down syndrome and congenital myasthenic syndrome 18. Orthologous to human SNAP25 (synaptosome associated protein 25); PARTICIPATES IN insulin secretion pathway; INTERACTS WITH 1,3-dinitrobenzene; 2,2',4,4'-Tetrabromodiphenyl ether; 2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: MGC105414; SNAP-25; SNAP-25a; SNAP-25B; SUP; super protein; Synaptosomal-accosiated protein, 25 kDa; synaptosomal-associated 25 kDa protein; synaptosomal-associated protein; synaptosomal-associated protein 25; Synaptosomal-associated protein 25 kDa; synaptosomal-associated protein, 25 kDa
Orthologs:
Homo sapiens (human) : SNAP25 (synaptosome associated protein 25)  HGNC  Alliance
Mus musculus (house mouse) : Snap25 (synaptosomal-associated protein 25)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Snap25 (synaptosome associated protein 25)
Pan paniscus (bonobo/pygmy chimpanzee) : SNAP25 (synaptosome associated protein 25)
Canis lupus familiaris (dog) : SNAP25 (synaptosome associated protein 25)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Snap25 (synaptosome associated protein 25)
Sus scrofa (pig) : SNAP25 (synaptosome associated protein 25)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly; Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.03129,697,408 - 129,788,417 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.03136,182,051 - 136,269,422 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43124,806,637 - 124,894,653 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13124,712,177 - 124,800,221 (+)NCBI
Celera3122,761,455 - 122,842,679 (+)NCBICelera
Cytogenetic Map3q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Snap25
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3728
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.