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Gene: SNAP25 (synaptosome associated protein 25) Homo sapiens
Symbol: SNAP25
Name: synaptosome associated protein 25
Description: Exhibits syntaxin-1 binding activity. Predicted to be involved in synaptic vesicle fusion to presynaptic active zone membrane and synaptic vesicle priming. Localizes to SNARE complex and cytoskeleton. Colocalizes with BLOC-1 complex and vesicle. Implicated in Down syndrome and congenital myasthenic syndrome 18.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: bA416N4.2; CMS18; dJ1068F16.2; FLJ23079; resistance to inhibitors of cholinesterase 4 homolog; RIC-4; RIC4; SEC9; SNAP; SNAP-25; SUP; super protein; synaptosomal-associated 25 kDa protein; synaptosomal-associated protein; synaptosomal-associated protein 25; synaptosomal-associated protein, 25kD; synaptosomal-associated protein, 25kDa; synaptosome associated protein 25kDa
Mus musculus (house mouse) : Snap25 (synaptosomal-associated protein 25)  MGI  Alliance
Rattus norvegicus (Norway rat) : Snap25 (synaptosome associated protein 25)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Snap25 (synaptosome associated protein 25)
Pan paniscus (bonobo/pygmy chimpanzee) : SNAP25 (synaptosome associated protein 25)
Canis lupus familiaris (dog) : SNAP25 (synaptosome associated protein 25)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Snap25 (synaptosome associated protein 25)
Sus scrofa (pig) : SNAP25 (synaptosome associated protein 25)
Chlorocebus sabaeus (African green monkey) : SNAP25 (synaptosome associated protein 25)
Heterocephalus glaber (naked mole-rat) : Snap25 (synaptosome associated protein 25)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl2010,218,830 - 10,307,418 (+)EnsemblGRCh38hg38GRCh38
GRCh382010,218,830 - 10,307,420 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372010,199,477 - 10,288,068 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362010,147,477 - 10,236,065 (+)NCBINCBI36hg18NCBI36
Build 342010,147,476 - 10,236,065NCBI
Celera2010,269,471 - 10,358,052 (+)NCBI
Cytogenetic Map20p12.2NCBI
HuRef2010,151,237 - 10,239,826 (+)NCBIHuRef
CHM1_12010,200,131 - 10,288,709 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on SNAP25
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 734151
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-03-31
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.