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Gene: Stx1a (syntaxin 1A) Rattus norvegicus
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Symbol: Stx1a
Name: syntaxin 1A
Description: Exhibits several functions, including ATP-dependent protein binding activity; ion channel binding activity; and protein binding activity, bridging. Involved in several processes, including SNARE complex assembly; positive regulation of secretion by cell; and synaptic vesicle exocytosis. Localizes to several cellular components, including the actomyosin; cytoplasm; and presynaptic membrane. Colocalizes with the voltage-gated potassium channel complex. Human ortholog(s) of this gene implicated in Creutzfeldt-Jakob disease and Hirschsprung's disease. Orthologous to human STX1A (syntaxin 1A); PARTICIPATES IN insulin secretion pathway; INTERACTS WITH (RS)-amphetamine; (S)-amphetamine; ammonium chloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: neuron-specific antigen HPC-1; P35A; synaptotagmin-associated 35 kDa protein; syntaxin 1 a; syntaxin 1 A (brain); syntaxin 1A (brain); syntaxin 1A (brain)-like; syntaxin-1A
Orthologs:
Homo sapiens (human) : STX1A (syntaxin 1A)  HGNC  Alliance
Mus musculus (house mouse) : Stx1a (syntaxin 1A (brain))  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Stx1a (syntaxin 1A)
Pan paniscus (bonobo/pygmy chimpanzee) : STX1A (syntaxin 1A)
Canis lupus familiaris (dog) : STX1A (syntaxin 1A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Stx1a (syntaxin 1A)
more info ...
Is Marker For: Strains:   BB/OK  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01224,682,050 - 24,710,002 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01226,682,320 - 26,710,272 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41222,737,112 - 22,765,064 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1223,405,260 - 23,432,900 (-)NCBICelera
Cytogenetic Map12q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Related Rat Strains
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Stx1a
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 69430
Created: 2001-11-27
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.