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Gene: Srsf2 (serine and arginine rich splicing factor 2) Rattus norvegicus
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Symbol: Srsf2
Name: serine and arginine rich splicing factor 2
Description: Exhibits protein kinase C binding activity. Involved in mitotic cell cycle and response to vitamin E. Localizes to the interchromatin granule and nuclear speck. Human ortholog(s) of this gene implicated in acute myeloid leukemia and myelodysplastic syndrome. Orthologous to human SRSF2 (serine and arginine rich splicing factor 2); PARTICIPATES IN spliceosome pathway; INTERACTS WITH (+)-alpha-tocopherol; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: MGC73009; SC-35; serine/arginine-rich splicing factor 2; Sfrs2; similar to splicing factor, arginine/serine-rich 2; splicing component, 35 kDa; splicing factor SC35; splicing factor, arginine/serine-rich 2; splicing factor, arginine/serine-rich 2 (SC-35)
Orthologs:
Homo sapiens (human) : SRSF2 (serine and arginine rich splicing factor 2)  HGNC  Alliance
Mus musculus (house mouse) : Srsf2 (serine and arginine-rich splicing factor 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Srsf2 (serine and arginine rich splicing factor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : SRSF2 (serine and arginine rich splicing factor 2)
Canis lupus familiaris (dog) : SRSF2 (serine and arginine rich splicing factor 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Srsf2 (serine and arginine rich splicing factor 2)
Sus scrofa (pig) : SRSF2 (serine and arginine rich splicing factor 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.010105,792,779 - 105,795,986 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.010105,451,332 - 105,454,538 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.410106,954,365 - 106,956,807 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.110106,968,870 - 106,971,311 (-)NCBI
Celera10100,620,618 - 100,623,797 (-)NCBICelera
Cytogenetic Map10q32.2NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Srsf2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1359422
Created: 2005-07-29
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.