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Gene: Arhgdia (Rho GDP dissociation inhibitor alpha) Rattus norvegicus
Symbol: Arhgdia
Name: Rho GDP dissociation inhibitor alpha
Description: Exhibits Hsp90 protein binding activity; enzyme binding activity; and fatty acid binding activity. Involved in several processes, including cellular response to mechanical stimulus; cellular response to redox state; and regulation of cell shape. Localizes to several cellular components, including cytosol; extracellular space; and synapse. Biomarker of hypertension. Human ortholog(s) of this gene implicated in nephrotic syndrome type 8. Orthologous to human ARHGDIA (Rho GDP dissociation inhibitor alpha); PARTICIPATES IN platelet-derived growth factor signaling pathway; neurotrophic factor signaling pathway; vasopressin signaling pathway via receptor type 2; INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; bisphenol A.
Type: protein-coding
Also known as: Bles01; MGC94886; rho GDI 1; Rho GDP dissociation inhibitor (GDI) alpha; rho GDP-dissociation inhibitor 1; rho-GDI alpha
Homo sapiens (human) : ARHGDIA (Rho GDP dissociation inhibitor alpha)  HGNC  Alliance
Mus musculus (house mouse) : Arhgdia (Rho GDP dissociation inhibitor (GDI) alpha)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Arhgdia (Rho GDP dissociation inhibitor alpha)
Pan paniscus (bonobo/pygmy chimpanzee) : ARHGDIA (Rho GDP dissociation inhibitor alpha)
Canis lupus familiaris (dog) : ARHGDIA (Rho GDP dissociation inhibitor alpha)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Arhgdia (Rho GDP dissociation inhibitor alpha)
Sus scrofa (pig) : ARHGDIA (Rho GDP dissociation inhibitor alpha)
Chlorocebus sabaeus (African green monkey) : ARHGDIA (Rho GDP dissociation inhibitor alpha)
Heterocephalus glaber (naked mole-rat) : Arhgdia (Rho GDP dissociation inhibitor alpha)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.010109,754,012 - 109,757,506 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl10109,754,004 - 109,757,550 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.010109,347,156 - 109,350,645 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.410109,967,771 - 109,971,260NCBIRGSC3.4rn4RGSC3.4
Celera10104,397,938 - 104,401,427 (-)NCBICelera
Cytogenetic Map10q32.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Arhgdia
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1359547
Created: 2005-07-29
Species: Rattus norvegicus
Last Modified: 2020-09-01
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.