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Gene: Arhgdia (Rho GDP dissociation inhibitor alpha) Rattus norvegicus
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Symbol: Arhgdia
Name: Rho GDP dissociation inhibitor alpha
Description: Exhibits Hsp90 protein binding activity; enzyme binding activity; and fatty acid binding activity. Involved in several processes, including cellular response to mechanical stimulus; cellular response to redox state; and regulation of cell shape. Localizes to several cellular components, including the cytosol; extracellular space; and synapse. Biomarker of hypertension. Human ortholog(s) of this gene implicated in nephrotic syndrome type 8. Orthologous to human ARHGDIA (Rho GDP dissociation inhibitor alpha); PARTICIPATES IN platelet-derived growth factor signaling pathway; neurotrophic factor signaling pathway; vasopressin signaling pathway via receptor type 2; INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Bles01; MGC94886; rho GDI 1; Rho GDP dissociation inhibitor (GDI) alpha; rho GDP-dissociation inhibitor 1; rho-GDI alpha
Orthologs:
Homo sapiens (human) : ARHGDIA (Rho GDP dissociation inhibitor alpha)  HGNC  Alliance
Mus musculus (house mouse) : Arhgdia (Rho GDP dissociation inhibitor (GDI) alpha)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Arhgdia (Rho GDP dissociation inhibitor alpha)
Pan paniscus (bonobo/pygmy chimpanzee) : ARHGDIA (Rho GDP dissociation inhibitor alpha)
Canis lupus familiaris (dog) : ARHGDIA (Rho GDP dissociation inhibitor alpha)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Arhgdia (Rho GDP dissociation inhibitor alpha)
Sus scrofa (pig) : ARHGDIA (Rho GDP dissociation inhibitor alpha)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.010109,754,012 - 109,757,506 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.010109,347,156 - 109,350,645 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.410109,967,771 - 109,971,260NCBIRGSC3.4rn4RGSC3.4
Celera10104,397,938 - 104,401,427 (-)NCBICelera
Cytogenetic Map10q32.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Arhgdia
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1359547
Created: 2005-07-29
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.