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Gene: Sox9 (SRY-box transcription factor 9) Rattus norvegicus
Symbol: Sox9
Name: SRY-box transcription factor 9
RGD ID: 620474
Description: Exhibits DNA-binding transcription activator activity, RNA polymerase II-specific; bHLH transcription factor binding activity; and cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including Sertoli cell development; cAMP-mediated signaling; and cartilage development. Localizes to transcription regulator complex. Human ortholog(s) of this gene implicated in 46,XX sex reversal 2; 46,XY sex reversal 10; and campomelic dysplasia. Orthologous to human SOX9 (SRY-box transcription factor 9); INTERACTS WITH (+)-taxifolin; (S)-nicotine; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: LOC100361122; LOC363699; SRY; SRY (sex determining region Y)-box 9; SRY (sex determining region Y)-box 9 (campomelic dysplasia, autosomal sex-reversal); SRY box 9; SRY-box containing gene 9; transcription factor SOX-9
Homo sapiens (human) : SOX9 (SRY-box transcription factor 9)  HGNC  Alliance
Mus musculus (house mouse) : Sox9 (SRY (sex determining region Y)-box 9)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sox9 (SRY-box transcription factor 9)
Pan paniscus (bonobo/pygmy chimpanzee) : SOX9 (SRY-box transcription factor 9)
Canis lupus familiaris (dog) : SOX9 (SRY-box transcription factor 9)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sox9 (SRY-box transcription factor 9)
Sus scrofa (pig) : SOX9 (SRY-box transcription factor 9)
Chlorocebus sabaeus (African green monkey) : SOX9 (SRY-box transcription factor 9)
Heterocephalus glaber (naked mole-rat) : Sox9 (SRY-box transcription factor 9)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.010101,288,528 - 101,294,030 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl10101,288,489 - 101,293,379 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.010100,964,754 - 100,970,581 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.410102,392,187 - 102,394,256 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.110102,408,236 - 102,408,622 (+)NCBI
Celera1096,424,278 - 96,429,703 (+)NCBICelera
Cytogenetic Map10q32.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Sox9
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620474
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.