Slc26a11 (solute carrier family 26 member 11)

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Gene: Slc26a11 (solute carrier family 26 member 11) Rattus norvegicus

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Symbol:

Slc26a11

Name:

solute carrier family 26 member 11

RGD ID:

1306178

Description:

Predicted to enable chloride channel activity; chloride:bicarbonate antiporter activity; and sulfate transmembrane transporter activity. Predicted to be involved in sulfate transport. Predicted to be located in several cellular components, including apical plasma membrane; basolateral plasma membrane; and lysosomal membrane. Predicted to be active in plasma membrane. Orthologous to human SLC26A11 (solute carrier family 26 member 11); INTERACTS WITH bisphenol A; gentamycin; paracetamol.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC360670; sodium-independent sulfate anion transporter; solute carrier family 26 (anion exchanger), member 11; solute carrier family 26, member 11

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	SLC26A11 (solute carrier family 26 member 11)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Slc26a11 (solute carrier family 26, member 11)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Slc26a11 (solute carrier family 26 member 11)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	SLC26A11 (solute carrier family 26 member 11)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	SLC26A11 (solute carrier family 26 member 11)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Slc26a11 (solute carrier family 26 member 11)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	SLC26A11 (solute carrier family 26 member 11)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	SLC26A11 (solute carrier family 26 member 11)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Slc26a11 (solute carrier family 26 member 11)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	SLC26A11 (solute carrier family 26 member 11)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Slc26a11 (solute carrier family 26, member 11)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	slc26a11 (solute carrier family 26 member 11)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG5002	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	SUL1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	SUL2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG5404	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER\|PhylomeDB)
Drosophila melanogaster (fruit fly):	CG6125	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER\|PhylomeDB)
Drosophila melanogaster (fruit fly):	CG6928	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OrthoFinder\|PANTHER\|PhylomeDB)
Drosophila melanogaster (fruit fly):	CG7912	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG9702	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OrthoFinder\|PANTHER\|PhylomeDB)
Drosophila melanogaster (fruit fly):	CG9717	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OrthoFinder\|PANTHER\|PhylomeDB)
Drosophila melanogaster (fruit fly):	Esp	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	slc26a11	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	105,112,020 - 105,134,393 (+)	NCBI		GRCr8
mRatBN7.2	10	104,613,498 - 104,635,873 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	104,613,564 - 104,635,970 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	10	109,716,296 - 109,738,585 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	109,179,324 - 109,201,613 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	104,534,132 - 104,556,507 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	108,479,105 - 108,504,188 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	108,480,368 - 108,503,706 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	10	108,085,544 - 108,110,760 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	10	108,730,993 - 108,741,761 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	10	108,745,495 - 108,755,783 (+)	NCBI
Celera	10	103,160,454 - 103,178,345 (+)	NCBI		Celera
Cytogenetic Map	10	q32.3	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

idiopathic generalized epilepsy (ISO)

mucopolysaccharidosis (ISO)

mucopolysaccharidosis III (ISO)

mucopolysaccharidosis type IIIA (ISO)

pityriasis rubra pilaris (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

17beta-estradiol (ISO)

2-methylcholine (ISO)

3,3',5,5'-tetrabromobisphenol A (ISO)

3,4-methylenedioxymethamphetamine (ISO)

3-iodothyronamine (ISO)

4-\{[(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)carbonyl]amino\}benzoic acid (ISO)

acrolein (ISO)

alpha-pinene (ISO)

aristolochic acid A (ISO)

arsane (ISO)

arsenic atom (ISO)

benzo[a]pyrene (ISO)

benzo[b]fluoranthene (ISO)

bisphenol A (EXP,ISO)

bortezomib (ISO)

carbon nanotube (ISO)

cisplatin (ISO)

copper(II) sulfate (ISO)

coumestrol (ISO)

cyclosporin A (ISO)

DDE (ISO)

doxorubicin (ISO)

Enterolactone (ISO)

epoxiconazole (ISO)

FR900359 (ISO)

gentamycin (EXP)

iron atom (ISO)

iron(0) (ISO)

lead(0) (ISO)

ozone (ISO)

paracetamol (EXP,ISO)

PCB138 (EXP)

perfluorooctanoic acid (ISO)

resveratrol (ISO)

silver atom (ISO)

silver(0) (ISO)

sodium arsenite (ISO)

tetraphene (ISO)

valproic acid (ISO)

vitamin D (ISO)

zidovudine (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

chloride transmembrane transport (IEA)

sulfate transmembrane transport (IEA)

sulfate transport (ISO)

Cellular Component

apical plasma membrane (ISO)

basolateral plasma membrane (ISO)

endoplasmic reticulum (ISO)

Golgi apparatus (IEA,ISO)

intracellular membrane-bounded organelle (ISO)

lysosomal membrane (ISO)

membrane (ISO)

nucleoplasm (IEA,ISO)

plasma membrane (IBA,ISO)

Molecular Function

chloride channel activity (ISO)

chloride:bicarbonate antiporter activity (ISO)

monoatomic anion transmembrane transporter activity (ISO)

protein binding (ISO)

secondary active sulfate transmembrane transporter activity (IEA)

sulfate transmembrane transporter activity (IBA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
3.	GOA pipeline	RGD automated data pipeline
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12626430	PMID:19056867	PMID:20957757	PMID:25910210	PMID:37380823

Genomics

Comparative Map Data

Slc26a11
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	105,112,020 - 105,134,393 (+)	NCBI		GRCr8
mRatBN7.2	10	104,613,498 - 104,635,873 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	104,613,564 - 104,635,970 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	10	109,716,296 - 109,738,585 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	109,179,324 - 109,201,613 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	104,534,132 - 104,556,507 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	108,479,105 - 108,504,188 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	108,480,368 - 108,503,706 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	10	108,085,544 - 108,110,760 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	10	108,730,993 - 108,741,761 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	10	108,745,495 - 108,755,783 (+)	NCBI
Celera	10	103,160,454 - 103,178,345 (+)	NCBI		Celera
Cytogenetic Map	10	q32.3	NCBI

SLC26A11
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	17	80,220,427 - 80,253,500 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	17	80,219,699 - 80,253,500 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	17	78,194,226 - 78,227,299 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	17	75,808,832 - 75,841,892 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	17	75,808,857 - 75,841,892	NCBI
Celera	17	74,838,390 - 74,854,977 (+)	NCBI		Celera
Cytogenetic Map	17	q25.3	NCBI
HuRef	17	73,634,468 - 73,667,603 (+)	NCBI		HuRef
CHM1_1	17	78,280,379 - 78,313,486 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	17	81,120,848 - 81,153,937 (+)	NCBI		T2T-CHM13v2.0

Slc26a11
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	119,246,328 - 119,271,902 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	11	119,246,383 - 119,271,905 (+)	Ensembl		GRCm39 Ensembl
GRCm38	11	119,355,509 - 119,381,076 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	119,355,557 - 119,381,079 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	11	119,216,871 - 119,242,390 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	11	119,171,647 - 119,197,166 (+)	NCBI		MGSCv36	mm8
Celera	11	131,103,839 - 131,129,014 (+)	NCBI		Celera
Cytogenetic Map	11	E2	NCBI
cM Map	11	83.36	NCBI

Slc26a11
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955506	2,684,259 - 2,700,837 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955506	2,683,637 - 2,701,889 (-)	NCBI	ChiLan1.0	ChiLan1.0

SLC26A11
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	19	96,799,964 - 96,833,341 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	17	101,699,763 - 101,733,107 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	17	74,647,880 - 74,681,247 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	17	80,381,942 - 80,414,210 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	17	80,381,942 - 80,414,210 (+)	Ensembl	panpan1.1		panPan2

SLC26A11
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	9	1,522,836 - 1,539,889 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	9	1,522,833 - 1,540,118 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	9	2,162,919 - 2,180,662 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	9	2,155,371 - 2,173,145 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	9	2,155,369 - 2,173,261 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	9	2,178,818 - 2,196,554 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	9	2,304,249 - 2,322,009 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	9	2,385,468 - 2,403,234 (-)	NCBI		UU_Cfam_GSD_1.0

Slc26a11
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	2,189,355 - 2,208,139 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936594	4,203,576 - 4,223,633 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936594	4,203,892 - 4,222,740 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SLC26A11
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	12	2,220,683 - 2,242,289 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	12	2,220,679 - 2,241,802 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	12	2,171,778 - 2,192,955 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SLC26A11
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	16	72,203,264 - 72,233,360 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666077	43,506,172 - 43,539,543 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Slc26a11
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624801	9,297,206 - 9,315,830 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624801	9,297,190 - 9,315,830 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Slc26a11
180 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	56
Count of miRNA genes:	54
Interacting mature miRNAs:	56
Transcripts:	ENSRNOT00000054987
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
12880384	Cm107	Cardiac mass QTL 107		0.001	heart mass (VT:0007028)	heart wet weight to body weight ratio (CMO:0002408)		90404397	107211142	Rat
1354641	Bvd2	Brain ventricular dilatation QTL 2	6.36	0.001	brain ventricle morphology trait (VT:0000822)	hydrocephalus severity score (CMO:0001881)	10	93223816	107057807	Rat
12880385	Cm108	Cardiac mass QTL 108		0.001	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)		90404397	107211142	Rat
2303589	Bw87	Body weight QTL 87	2		body mass (VT:0001259)	body weight (CMO:0000012)	10	81285008	107211142	Rat
2317029	Aia19	Adjuvant induced arthritis QTL 19	2.98		joint integrity trait (VT:0010548)	left rear ankle joint diameter (CMO:0002149)	10	66978955	107211142	Rat
12880396	Am13	Aortic mass QTL 13		0.001	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	10	90404397	107211142	Rat
61449	Ciaa2	CIA Autoantibody QTL 2	7.1		blood autoantibody amount (VT:0003725)	calculated serum anti-type 2 collagen antibody titer (CMO:0001279)	10	63221094	107211142	Rat
12880398	Kidm67	Kidney mass QTL 67		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	10	90404397	107211142	Rat
61387	Bp1	Blood pressure QTL 1	5.1		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	10	51770177	107211142	Rat
2317039	Aia6	Adjuvant induced arthritis QTL 6	4.31		joint integrity trait (VT:0010548)	right rear ankle joint diameter (CMO:0002150)	10	66978955	107211142	Rat
1298078	Stresp5	Stress response QTL 5	2.99	0.00025	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	10	42045676	104670812	Rat
12880395	Cm109	Cardiac mass QTL 109		0.001	heart right ventricle mass (VT:0007033)	heart right ventricle weight to body weight ratio (CMO:0000914)	10	90404397	107211142	Rat
1579915	Bp280	Blood pressure QTL 280		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	90404397	107211142	Rat
61396	Bp9	Blood pressure QTL 9	4.8	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	68420376	107211142	Rat
2298548	Neuinf7	Neuroinflammation QTL 7	3.4		nervous system integrity trait (VT:0010566)	spinal cord RT1-B protein level (CMO:0002132)	10	72224939	107211142	Rat
1302404	Cia27	Collagen induced arthritis QTL 27	2.6	0.0045	joint integrity trait (VT:0010548)	experimental arthritis severity measurement (CMO:0001459)	10	76452683	107211142	Rat
634320	Niddm49	Non-insulin dependent diabetes mellitus QTL 49	4.41		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	10	88539139	107211142	Rat
2317754	Glom25	Glomerulus QTL 25	3.5		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	10	82685200	107211142	Rat
70171	Cari1	Carrageenan-induced inflammation QTL 1	4.9	0.0005	hypodermis integrity trait (VT:0010550)	inflammatory exudate volume (CMO:0001429)	10	53797385	107211142	Rat
1331791	Cm31	Cardiac mass QTL 31	3.84606		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	10	29299504	107211142	Rat
10450498	Bp384	Blood pressure QTL 384		0.002	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	67750049	107211142	Rat
4889492	Pancm2	Pancreatic morphology QTL 2	3.2		pancreatic beta cell morphology trait (VT:0005217)	ratio of insulin-positive cell area to total area of splenic region of pancreas (CMO:0001814)	10	76748906	107211142	Rat
6893366	Bw106	Body weight QTL 106	0.3	0.47	body mass (VT:0001259)	body weight (CMO:0000012)	10	70199100	107211142	Rat
10450493	Bp382	Blood pressure QTL 382		0.002	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	94759759	107211142	Rat
1578672	Bmd16	Bone mineral density QTL 16	6.2		femur mineral mass (VT:0010011)	compact volumetric bone mineral density (CMO:0001730)	10	96703043	107057807	Rat
2293646	Bss25	Bone structure and strength QTL 25	10.96	0.0001	femur morphology trait (VT:0000559)	femur cross-sectional area (CMO:0001661)	10	69738412	107211142	Rat
2313103	Bss80	Bone structure and strength QTL 80	2	0.0001	tibia strength trait (VT:1000284)	tibia midshaft endosteal cross-sectional area (CMO:0001716)	10	62057807	107057807	Rat
2303118	Mamtr7	Mammary tumor resistance QTL 7		0.003	mammary gland integrity trait (VT:0010552)	mammary tumor growth rate (CMO:0000344)	10	9658275	104670812	Rat
2300172	Bmd57	Bone mineral density QTL 57	9.8	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	10	69738412	107211142	Rat
70193	Mcs7	Mammary carcinoma susceptibility QTL 7	2.38		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	10	72224939	107211142	Rat
2313105	Bss79	Bone structure and strength QTL 79	1.8	0.0001	tibia size trait (VT:0100001)	tibia midshaft cross-sectional area (CMO:0001717)	10	62057807	107057807	Rat
61363	Oia3	Oil induced arthritis QTL 3		0.001	joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	87307617	107211142	Rat
2292438	Bp311	Blood pressure QTL 311			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	76246085	107211142	Rat
2316949	Gluco60	Glucose level QTL 60	3.7		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	10	14487011	107057807	Rat
2292436	Bp310	Blood pressure QTL 310			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	94759759	107211142	Rat
724530	Bp149	Blood pressure QTL 149		0.0001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	90627439	107211142	Rat
631539	Oia6	Oil induced arthritis QTL 6			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	97010147	104670812	Rat
1300137	Bp186	Blood pressure QTL 186	3.57		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	10	90627439	107057807	Rat
631538	Oia5	Oil induced arthritis QTL 5			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	87055121	107211142	Rat
1642980	Bp300	Blood pressure QTL 300			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	68383129	107211142	Rat
2293663	Bss33	Bone structure and strength QTL 33	9.34	0.0001	femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	10	69738412	107211142	Rat
1578663	Bss18	Bone structure and strength QTL 18	3.6		femur width (VT:1000666)	femoral neck width (CMO:0001695)	10	96703043	107057807	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	60	31

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001398807	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006220967	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006220968	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006247940	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039087531	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039087532	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039087533	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039087534	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039087535	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039087536	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473948	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000010	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000054987 ⟹ ENSRNOP00000051870

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	10	104,613,564 - 104,635,970 (+)	Ensembl
Rnor_6.0 Ensembl	10	108,480,368 - 108,503,706 (+)	Ensembl

RefSeq Acc Id:

NM_001398807 ⟹ NP_001385736

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	105,112,020 - 105,134,393 (+)	NCBI
mRatBN7.2	10	104,613,498 - 104,635,873 (+)	NCBI

RefSeq Acc Id:

XM_039087531 ⟹ XP_038943459

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	105,112,073 - 105,134,393 (+)	NCBI
mRatBN7.2	10	104,613,551 - 104,635,873 (+)	NCBI

RefSeq Acc Id:

XM_039087532 ⟹ XP_038943460

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	105,112,648 - 105,134,393 (+)	NCBI
mRatBN7.2	10	104,614,113 - 104,635,873 (+)	NCBI

RefSeq Acc Id:

XM_039087533 ⟹ XP_038943461

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	105,112,175 - 105,134,393 (+)	NCBI
mRatBN7.2	10	104,613,649 - 104,635,873 (+)	NCBI

RefSeq Acc Id:

XM_039087534 ⟹ XP_038943462

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	105,112,020 - 105,134,393 (+)	NCBI
mRatBN7.2	10	104,613,498 - 104,635,873 (+)	NCBI

RefSeq Acc Id:

XM_039087535 ⟹ XP_038943463

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	105,114,414 - 105,134,393 (+)	NCBI
mRatBN7.2	10	104,615,892 - 104,635,873 (+)	NCBI

RefSeq Acc Id:

XM_039087536 ⟹ XP_038943464

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	105,115,466 - 105,134,393 (+)	NCBI
mRatBN7.2	10	104,616,950 - 104,635,873 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001385736	(Get FASTA)	NCBI Sequence Viewer
	XP_038943459	(Get FASTA)	NCBI Sequence Viewer
	XP_038943460	(Get FASTA)	NCBI Sequence Viewer
	XP_038943461	(Get FASTA)	NCBI Sequence Viewer
	XP_038943462	(Get FASTA)	NCBI Sequence Viewer
	XP_038943463	(Get FASTA)	NCBI Sequence Viewer
	XP_038943464	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDM06789	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000051870.3

Ensembl Acc Id:

ENSRNOP00000051870 ⟸ ENSRNOT00000054987

RefSeq Acc Id:	XP_038943462 ⟸ XM_039087534
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_038943459 ⟸ XM_039087531
- Peptide Label:	isoform X1
- UniProtKB:	F1M067 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038943461 ⟸ XM_039087533
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038943460 ⟸ XM_039087532
- Peptide Label:	isoform X1
- UniProtKB:	F1M067 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038943463 ⟸ XM_039087535
- Peptide Label:	isoform X4

RefSeq Acc Id:	XP_038943464 ⟸ XM_039087536
- Peptide Label:	isoform X5

RefSeq Acc Id:	NP_001385736 ⟸ NM_001398807
- UniProtKB:	F1M067 (UniProtKB/TrEMBL)

Protein Domains

STAS

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-F1M067-F1-model_v2	AlphaFold	F1M067	1-592	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1306178	AgrOrtholog
BioCyc Gene	G2FUF-22490	BioCyc
Ensembl Genes	ENSRNOG00000030537	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000054987.3	UniProtKB/TrEMBL
Gene3D-CATH	3.30.750.24	UniProtKB/TrEMBL
InterPro	S04_transporter_CS	UniProtKB/TrEMBL
	SO4_transptr/STAS	UniProtKB/TrEMBL
	STAS_dom_sf	UniProtKB/TrEMBL
	Sul_anion_transpt	UniProtKB/TrEMBL
	Sulph_transpt	UniProtKB/TrEMBL
NCBI Gene	360670	ENTREZGENE
PANTHER	PTHR11814	UniProtKB/TrEMBL
	SODIUM-INDEPENDENT SULFATE ANION TRANSPORTER	UniProtKB/TrEMBL
Pfam	STAS	UniProtKB/TrEMBL
	Sulfate_transp	UniProtKB/TrEMBL
PhenoGen	Slc26a11	PhenoGen
PROSITE	SLC26A	UniProtKB/TrEMBL
	STAS	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000030537	RatGTEx
Superfamily-SCOP	STAS	UniProtKB/TrEMBL
UniProt	F1M067	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-02-24	Slc26a11	solute carrier family 26 member 11	Slc26a11	solute carrier family 26 (anion exchanger), member 11	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2013-08-02	Slc26a11	solute carrier family 26 (anion exchanger), member 11	Slc26a11	solute carrier family 26, member 11	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	Slc26a11	solute carrier family 26, member 11	Slc26a11_predicted	solute carrier family 26, member 11 (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Slc26a11_predicted	solute carrier family 26, member 11 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar