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Gene: MIR21 (microRNA 21) Homo sapiens
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Symbol: MIR21
Name: microRNA 21
RGD ID: 1349265
Description: Predicted to have mRNA 3'-UTR binding activity and mRNA binding activity involved in posttranscriptional gene silencing. Predicted to be involved in several processes, including cellular response to cytokine stimulus; cellular response to dexamethasone stimulus; and regulation of gene expression. Predicted to localize to RISC complex. Biomarker of artery disease (multiple); chronic lymphocytic leukemia; hepatobiliary system cancer (multiple); and primary biliary cholangitis.
Type: ncrna
RefSeq Status: PROVISIONAL
Also known as: hsa-mir-21; miR-21; MIRN21; miRNA21
Orthologs:
Mus musculus (house mouse) : Mir21a (microRNA 21a)  MGI
Rattus norvegicus (Norway rat) : Mir21 (microRNA 21)  Alliance
Canis lupus familiaris (dog) : MIR21 (microRNA mir-21)
Sus scrofa (pig) : MIR21 (microRNA mir-21)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1759,841,266 - 59,841,337 (+)EnsemblGRCh38hg38GRCh38
GRCh381759,841,266 - 59,841,337 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371757,918,627 - 57,918,698 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361755,273,408 - 55,273,479 (+)NCBINCBI36hg18NCBI36
Celera1754,382,140 - 54,382,211 (+)NCBI
Cytogenetic Map17q23.1NCBI
HuRef1753,291,116 - 53,291,187 (+)NCBIHuRef
CHM1_11757,982,648 - 57,982,719 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Clinical Variants

Additional Information

External Database Links
 
More on MIR21
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1349265
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-10-06
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.