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Gene: Plk2 (polo-like kinase 2) Rattus norvegicus
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Symbol: Plk2
Name: polo-like kinase 2
Description: Exhibits protein serine/threonine kinase activity. Involved in several processes, including Rap protein signal transduction; negative regulation of dendritic spine development; and regulation of synaptic plasticity. Localizes to the dendrite. Orthologous to human PLK2 (polo like kinase 2); INTERACTS WITH (+)-schisandrin B; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1,2-dimethylhydrazine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: PLK-2; polo-like kinase 1; polo-like kinase 2 (Drosophila); serine/threonine-protein kinase PLK2; serine/threonine-protein kinase SNK; serum-inducible kinase; Snk
Orthologs:
Homo sapiens (human) : PLK2 (polo like kinase 2)  HGNC  Alliance
Mus musculus (house mouse) : Plk2 (polo like kinase 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Plk2 (polo like kinase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : PLK2 (polo like kinase 2)
Canis lupus familiaris (dog) : PLK2 (polo like kinase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Plk2 (polo like kinase 2)
Sus scrofa (pig) : PLK2 (polo like kinase 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0241,911,143 - 41,916,901 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0260,970,300 - 60,976,058 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4241,800,745 - 41,806,503 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1241,721,113 - 41,726,872 (+)NCBI
Celera237,785,007 - 37,790,765 (+)NCBICelera
Cytogenetic Map2q14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Plk2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620760
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.