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Strain Registration

Strain: DA.F344-(D10Arb20-D10Arb22)/Arb

Symbol: DA.F344-(D10Arb20-D10Arb22)/Arb
Strain: DA.F344-(D10Arb20-D10Arb22)
Substrain: Arb
RGD ID: 631282
Citation ID: RRID:RGD_631282
Ontology ID: RS:0000209
Also Known As: DA.F344-(D10Rat37-D10Arb22)/Arb; DA.F344-(D10Arb20-D10Arb22)/Arb; DA.F344-(D10Arb20-D10Arb22); DA.F344(Cia5)
Type: congenic
Available Source: Not Available
Origination: Arthritis and Rheumatism Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, NIH, Bethesda, MD, USA
Description: This speed congenic strain contains an F344 chromsome 10 segment transferred to a DA background.
Last Known Status: Extinct
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21023,444,813 - 104,060,283RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01024,483,076 - 107,857,673RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01024,340,447 - 107,484,761RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.41024,006,429 - 24,006,612RGD_MAPPER_PIPELINERGSC3.4





Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype

Phenotype Values via PhenoMiner     Click to see Annotation Detail View
Options:  View chart  |  Download data table  |  View expanded data table


References

References - curated
# Reference Title Reference Citation
1. The non-MHC quantitative trait locus Cia5 contains three major arthritis genes that differentially regulate disease severity, pannus formation, and joint damage in collagen- and pristane-induced arthritis. Brenner M, etal., J Immunol 2005 Jun 15;174(12):7894-903.
2. Evaluation of quantitative trait loci regulating severity of mycobacterial adjuvant-induced arthritis in monocongenic and polycongenic rats: identification of a new regulatory locus on rat chromosome 10 and evidence of overlap with rheumatoid arthritis susceptibility loci. Joe B, etal., Arthritis Rheum 2002 Apr;46(4):1075-85.
3. Genetic dissection of collagen-induced arthritis in Chromosome 10 quantitative trait locus speed congenic rats: evidence for more than one regulatory locus and sex influences. Joe B, etal., Immunogenetics 2000 Sep;51(11):930-44.
4. COLLAGEN-INDUCED ARTHRITIS SEVERITY LOCI ON RAT CHROMOSOME 10 (RNO10) ALSO REGULATE DISEASE IN THREE OTHER EXPERIMENTALLY INDUCED MODELS OF ARTHRITIS Joe B., etal. 2000 Arthritis Rheum 43:S233
5. Modulation of multiple experimental arthritis models by collagen-induced arthritis quantitative trait loci isolated in congenic rat lines: different effects of non-major histocompatibility complex quantitative trait loci in males and females. Remmers EF, etal., Arthritis Rheum 2002 Aug;46(8):2225-34.
6. RGD Strain RSO annotation pipeline RGD Automated Pipelines

Region

Position Markers

Flank 1 / 1 (D10Arb20)
Rat AssemblyChrPosition (strand)Source
GRCr81023,948,641 - 23,948,818 (+)Marker Load Pipeline
mRatBN7.21023,444,813 - 23,444,992 (+)MAPPER
Rnor_6.01024,483,076 - 24,483,258NCBI
Rnor_5.01024,340,447 - 24,340,629UniSTS
RGSC_v3.41024,006,429 - 24,006,612RGD
RGSC_v3.41024,006,430 - 24,006,612UniSTS
RGSC_v3.11024,007,478 - 24,007,661RGD
Celera1023,044,707 - 23,044,873UniSTS
Cytogenetic Map10 RGD

Flank 2 / 1 (D10Arb22)
Rat AssemblyChrPosition (strand)Source
mRatBN7.210104,060,133 - 104,060,283 (+)MAPPER
Rnor_6.010107,857,524 - 107,857,673NCBI
Rnor_5.010107,484,612 - 107,484,761UniSTS
Celera10102,615,292 - 102,615,441UniSTS
Cytogenetic Map10q32.3UniSTS
Strain QTL Data
Symbol Name Trait
Aia5 Adjuvant induced arthritis QTL 5 joint integrity trait   (VT:0010548)    
Pia10 Pristane induced arthritis QTL 10 joint integrity trait   (VT:0010548)    

Additional Information

RGD Curation Notes
Note Type Note Reference
strain_life_disease Develops less severe collagen-induced arthritis than the parental DA strain. 631168

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-04-07 DA.F344-(D10Arb20-D10Arb22)/Arb    DA.F344-(D10Arb20-D10Arb22)/Arb    Name updated 68913 APPROVED
2015-04-07 DA.F344-(D10Arb20-D10Arb22)/Arb    DA.F344-(D10Arb20-D10Arb22)/Arb    Name updated 68913 APPROVED
2015-04-07 DA.F344-(D10Arb20-D10Arb22)/Arb    DA.F344-(D10Arb20-D10Arb22)/Arb    Name updated 68913 APPROVED
2015-04-07 DA.F344-(D10Arb20-D10Arb22)/Arb    DA.F344-(D10Arb20-D10Arb22)/Arb    Name updated 68913 APPROVED
2015-04-07 DA.F344-(D10Arb20-D10Arb22)/Arb    DA.F344-(D10Arb20-D10Arb22)/Arb    Name updated 68913 APPROVED
2015-04-07 DA.F344-(D10Arb20-D10Arb22)/Arb    DA.F344-(D10Arb20-D10Arb22)/Arb    Name updated 68913 APPROVED
2013-09-06 DA.F344-(D10Arb20-D10Arb22)/Arb    DA.F344-(D10Rat37-D10Arb22)/Arb    Name updated 68913 APPROVED
2013-09-06 DA.F344-(D10Arb20-D10Arb22)/Arb    DA.F344-(D10Rat37-D10Arb22)/Arb    Name updated 68913 APPROVED
2013-09-06 DA.F344-(D10Arb20-D10Arb22)/Arb    DA.F344-(D10Rat37-D10Arb22)/Arb    Symbol updated 68687 APPROVED
2013-09-06 DA.F344-(D10Arb20-D10Arb22)/Arb    DA.F344-(D10Rat37-D10Arb22)/Arb    Symbol updated 68687 APPROVED
2013-05-20 DA.F344-(D10Rat37-D10Arb22)/Arb    DA.F344-(D10Rat37-D10Arb22)    Symbol updated 68687 APPROVED
2013-05-20 DA.F344-(D10Rat37-D10Arb22)/Arb    DA.F344-(D10Rat37-D10Arb22)    Name updated 68913 APPROVED
2013-05-20 DA.F344-(D10Rat37-D10Arb22)/Arb    DA.F344-(D10Rat37-D10Arb22)    Symbol updated 68687 APPROVED
2013-05-20 DA.F344-(D10Rat37-D10Arb22)/Arb    DA.F344-(D10Rat37-D10Arb22)    Name updated 68913 APPROVED