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Strain Registration

Strain: SS.MNS-(D10M11Mit119-D10Mit11)/Jr

Symbol: SS.MNS-(D10M11Mit119-D10Mit11)/Jr
Strain: SS.MNS-(D10M11Mit119-D10Mit11)
Substrain: Jr
RGD ID: 631587
Citation ID: RRID:RGD_631587
Ontology ID: RS:0000892
Alleles: Ace
Previously known as: SS/Jr.MNS-(D10Mco1-D10Mco6)/Mco; S.M(10b); S.MNS(10b); SS.MNS-(D10M11Mit119-D10Mit11)/Jr; Chr 10 congenic
Type: congenic
Source: Medical College of Ohio, Toledo
Origin: This congenic strain is derived by introgressing a desired region of chr 10 from MNS to the SS/Jr recipient.
Last Known Status: Unknown
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21066,743,655 - 98,003,205RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01069,123,603 - 101,482,600RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01068,786,307 - 101,157,704RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.41069,986,912 - 102,587,587RGD_MAPPER_PIPELINERGSC3.4





Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype

Phenotype Values via PhenoMiner     Click to see Annotation Detail View
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References

References - curated
# Reference Title Reference Citation
1. Linkage map and congenic strains to localize blood pressure QTL on rat chromosome 10. Dukhanina OI, etal., Mamm Genome 1997 Apr;8(4):229-35.
2. Two linked blood pressure quantitative trait loci on chromosome 10 defined by dahl rat congenic strains. Garrett MR, etal., Hypertension 2001 Oct;38(4):779-85.
3. Construction of a double congenic strain to prove an epistatic interaction on blood pressure between rat chromosomes 2 and 10. Rapp JP, etal., J Clin Invest 1998 Apr 15;101(8):1591-5.
4. RGD Strain RSO annotation pipeline RGD Automated Pipelines

Region

Position Markers

Flank 1 / 1 (D10Mco1)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21066,743,655 - 66,743,848 (+)MAPPER
Rnor_6.01069,123,603 - 69,123,793NCBI
Rnor_5.01068,786,307 - 68,786,497UniSTS
RGSC_v3.41069,986,912 - 69,987,103RGD
RGSC_v3.41069,986,913 - 69,987,103UniSTS
RGSC_v3.11070,000,535 - 70,000,726RGD
Celera1065,692,716 - 65,692,906UniSTS
Cytogenetic Map10q26UniSTS

Flank 2 / 1 (D10Mco6)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21098,003,019 - 98,003,205 (+)MAPPER
Rnor_6.010101,482,415 - 101,482,600NCBI
Rnor_5.010101,157,519 - 101,157,704UniSTS
RGSC_v3.410102,587,401 - 102,587,587RGD
RGSC_v3.410102,587,402 - 102,587,587UniSTS
RGSC_v3.110102,601,771 - 102,601,957RGD
Celera1096,621,286 - 96,621,471UniSTS
Cytogenetic Map10 RGD
Strain QTL Data
Symbol Name Trait
Bp249 Blood pressure QTL 249 arterial blood pressure trait   (VT:2000000)    

Additional Information

RGD Curation Notes
Note Type Note Reference
strain_characteristics Contains 31 cM segment from D10MCo6 to D10Mco1 that localizes a blood pressure QTL. 619626
strain_life_disease The blood pressure is significantly reduced approximately by 40mm of Hg along with lower body weight and heart weight. 619626