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GENE - TERM ANNOTATION REPORT

RGD ID: 2493
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ace
Name: angiotensin I converting enzyme
Acc ID: DOID:0050855
Term: renal fibrosis
Definition: A kidney disease that is characterized by progressive detrimental connective tissue deposition of the kidney parenchyma leading to deterioration of renal function. (DO)
Definition Source(s): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2776335/ "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
AcetreatmentIMP 12879403RGD  
Ace ISOACE (Homo sapiens)8158033RGDprotein:decreased expression:renal medulla, renal cortex, brush border epithelial cell (human) 
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