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Gene: Ets1 (ETS proto-oncogene 1, transcription factor) Rattus norvegicus
Symbol: Ets1
Name: ETS proto-oncogene 1, transcription factor
Description: Exhibits histone acetyltransferase binding activity and sequence-specific DNA binding activity. Involved in several processes, including angiogenesis involved in wound healing; diencephalon development; and estrous cycle. Localizes to nucleus. Human ortholog(s) of this gene implicated in type 1 diabetes mellitus. Orthologous to human ETS1 (ETS proto-oncogene 1, transcription factor); PARTICIPATES IN altered p53 signaling pathway; hypoxia inducible factor pathway; interleukin-4 signaling pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 3,3',4,4',5-pentachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Ets avian erythroblastosis virus E2 oncogene homolog 1 (tumor progression locus 1); Ets-1; Etsoncb; MGC124638; p54; protein C-ets-1; Tpl1; v-ets avian erythroblastosis virus E26 oncogene homolog 1; v-ets erythroblastosis virus E26 oncogene homolog 1
Homo sapiens (human) : ETS1 (ETS proto-oncogene 1, transcription factor)  HGNC  Alliance
Mus musculus (house mouse) : Ets1 (E26 avian leukemia oncogene 1, 5' domain)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ets1 (ETS proto-oncogene 1, transcription factor)
Pan paniscus (bonobo/pygmy chimpanzee) : ETS1 (ETS proto-oncogene 1, transcription factor)
Canis lupus familiaris (dog) : ETS1 (ETS proto-oncogene 1, transcription factor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ets1 (ETS proto-oncogene 1, transcription factor)
Sus scrofa (pig) : ETS1 (ETS proto-oncogene 1, transcription factor)
Chlorocebus sabaeus (African green monkey) : ETS1 (ETS proto-oncogene 1, transcription factor)
Heterocephalus glaber (naked mole-rat) : Ets1 (ETS proto-oncogene 1, transcription factor)
more info ...
Allele / Splice: Ets1em1Mcwi  
Genetic Models: SS-Ets1em1Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0833,756,634 - 33,879,625 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl833,816,386 - 33,879,625 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0833,798,598 - 33,921,593 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4832,481,694 - 32,545,237 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1832,490,458 - 32,553,970 (+)NCBI
Celera832,555,513 - 32,617,691 (+)NCBICelera
Cytogenetic Map8q21NCBI
RH 3.4 Map8268.3RGD
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Ets1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2583
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-07-28
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.