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Gene: Ets1 (ETS proto-oncogene 1, transcription factor) Rattus norvegicus
Symbol: Ets1
Name: ETS proto-oncogene 1, transcription factor
Description: Exhibits histone acetyltransferase binding activity and sequence-specific DNA binding activity. Involved in several processes, including angiogenesis involved in wound healing; diencephalon development; and estrous cycle. Localizes to the nucleus. Human ortholog(s) of this gene implicated in type 1 diabetes mellitus. Orthologous to human ETS1 (ETS proto-oncogene 1, transcription factor); PARTICIPATES IN altered p53 signaling pathway; hypoxia inducible factor pathway; interleukin-4 signaling pathway; INTERACTS WITH (RS)-amphetamine; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1-naphthyl isothiocyanate.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Ets avian erythroblastosis virus E2 oncogene homolog 1 (tumor progression locus 1); Ets-1; Etsoncb; MGC124638; p54; protein C-ets-1; Tpl1; v-ets avian erythroblastosis virus E26 oncogene homolog 1; v-ets erythroblastosis virus E26 oncogene homolog 1
Homo sapiens (human) : ETS1 (ETS proto-oncogene 1, transcription factor)  HGNC  Alliance
Mus musculus (house mouse) : Ets1 (E26 avian leukemia oncogene 1, 5' domain)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ets1 (ETS proto-oncogene 1, transcription factor)
Pan paniscus (bonobo/pygmy chimpanzee) : ETS1 (ETS proto-oncogene 1, transcription factor)
Canis lupus familiaris (dog) : ETS1 (ETS proto-oncogene 1, transcription factor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ets1 (ETS proto-oncogene 1, transcription factor)
Sus scrofa (pig) : ETS1 (ETS proto-oncogene 1, transcription factor)
more info ...
Allele / Splice: Ets1em1Mcwi  
Genetic Models: SS-Ets1em1Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0833,756,634 - 33,879,625 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0833,798,598 - 33,921,593 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4832,481,694 - 32,545,237 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1832,490,458 - 32,553,970 (+)NCBI
Celera832,555,513 - 32,617,691 (+)NCBICelera
Cytogenetic Map8q21NCBI
RH 3.4 Map8268.3RGD
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
More on Ets1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2583
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.