Ahr (aryl hydrocarbon receptor) - Rat Genome Database

Name: Ahr
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

	Submit Data \| Help \| Video Tutorials \| News \| Publications \| Download \| REST API \| Citing RGD \| Contact
	Search RGD Grant Resources Citing RGD About Us Contact Us Genes QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) (beta) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) RatMine GViewer (Genome Viewer) Overgo Probe Designer Aging & Age-Related Disease Cancer Cardiovascular Disease COVID-19 Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease Find Models new Genetic Models Autism Models PhenoMiner (Quantitative Phenotypes) Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes GERRC (Gene Editing Rat Resource Center) Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive Pathways Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Poster Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
	Advanced Search (OLGA)

Gene: Ahr (aryl hydrocarbon receptor) Rattus norvegicus

Analyze

Symbol:

Ahr

Name:

aryl hydrocarbon receptor

RGD ID:

2074

Description:

Enables nuclear receptor activity and toxic substance binding activity. Involved in several processes, including cellular response to organic cyclic compound; negative regulation of alkaline phosphatase activity; and regulation of nucleobase-containing compound metabolic process. Located in cytosol and nucleus. Human ortholog(s) of this gene implicated in retinitis pigmentosa 85. Orthologous to human AHR (aryl hydrocarbon receptor); PARTICIPATES IN aryl hydrocarbon receptor signaling pathway; INTERACTS WITH (+)-schisandrin B; (S)-colchicine; 1,10-phenanthroline.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

ah receptor

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	AHR (aryl hydrocarbon receptor)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Ahr (aryl-hydrocarbon receptor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Ahr (aryl hydrocarbon receptor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	AHR (aryl hydrocarbon receptor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	AHR (aryl hydrocarbon receptor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Ahr (aryl hydrocarbon receptor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	AHR (aryl hydrocarbon receptor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	AHR (aryl hydrocarbon receptor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Ahr (aryl hydrocarbon receptor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Mus musculus (house mouse):	Ahr (aryl-hydrocarbon receptor)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	AHR (aryl hydrocarbon receptor)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	ahr1b (aryl hydrocarbon receptor 1b)	Alliance	DIOPT (InParanoid\|OrthoInspector\|PANTHER\|SonicParanoid)
Danio rerio (zebrafish):	ahr1a (aryl hydrocarbon receptor 1a)	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER\|PhylomeDB)
Caenorhabditis elegans (roundworm):	ahr-1	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	ss	Alliance	DIOPT (Ensembl Compara\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Allele / Splice:

Ahr^em1Sage Ahr^em1Soar Ahr^em2Sage

Genetic Models:

SD-Ahr^em2Sage SD-Nr1i2^em1Sage Nr1i3^em1Sage Ahr^em1Sage SD-Ahr^em1Sage SD-Ahr^em1Soar

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	6	52,234,089 - 52,271,568 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	52,234,089 - 52,271,568 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	6	52,513,201 - 52,550,666 (-)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	6	52,828,075 - 52,865,540 (-)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	6	52,285,311 - 52,322,845 (-)	NCBI	Rnor_WKY
Rnor_6.0	6	54,963,990 - 55,001,806 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	54,963,990 - 55,001,464 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	6	64,589,066 - 64,624,078 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	6	54,205,104 - 54,240,268 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	6	54,206,846 - 54,243,423 (-)	NCBI
Celera	6	51,391,870 - 51,429,719 (-)	NCBI		Celera
RH 3.4 Map	6	350.2	RGD
Cytogenetic Map	6	q16	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

acanthosis nigricans (ISO)

Adult Pancreatic Cancer (ISO)

Animal Disease Models (ISO)

atherosclerosis (ISO)

atopic dermatitis (ISO)

Atrophy (ISO)

Behcet's disease (ISO)

Birth Weight (ISO)

bladder calculus (ISO)

bone resorption disease (ISO)

Breast Neoplasms (ISO)

Cardiomegaly (ISO)

Chemical and Drug Induced Liver Injury (ISO)

Chronobiology Disorders (ISO)

colitis (ISO)

congenital heart disease (ISO)

congenital nystagmus (ISO)

contact dermatitis (ISO)

disease of cellular proliferation (ISO)

disease of metabolism (ISO)

Dyslipidemias (ISO)

Endotoxemia (ISO)

Experimental Arthritis (ISO)

Experimental Neoplasms (ISO)

glucose intolerance (ISO)

Growth Disorders (ISO)

Hepatomegaly (ISO)

Hyperoxia (ISO)

Hyperpigmentation (ISO)

hypertension (ISO)

Hypertrophy (ISO)

Hyperventilation (ISO)

hypoglycemia (ISO)

Inflammation (ISO)

Insulin Resistance (ISO)

keratosis (ISO)

Left Ventricular Hypertrophy (ISO)

liver cirrhosis (ISO)

liver disease (ISO)

Liver Neoplasms (ISO)

lung adenocarcinoma (ISO)

Lung Injury (ISO)

male infertility (ISO)

Necrosis (ISO)

Neoplasm Invasiveness (ISO)

Neoplasm Metastasis (ISO)

non-alcoholic fatty liver disease (ISO)

obesity (ISO)

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations

Mammalian Phenotype

Send us a Message

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations

Mammalian Phenotype