Ahr (aryl hydrocarbon receptor) - Rat Genome Database

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Gene: Ahr (aryl hydrocarbon receptor) Rattus norvegicus
Analyze
Symbol: Ahr
Name: aryl hydrocarbon receptor
RGD ID: 2074
Description: Exhibits nuclear receptor activity and toxic substance binding activity. Involved in several processes, including cellular response to organic cyclic compound; negative regulation of alkaline phosphatase activity; and regulation of cellular macromolecule biosynthetic process. Localizes to cytosol and nucleus. Human ortholog(s) of this gene implicated in retinitis pigmentosa 85. Orthologous to human AHR (aryl hydrocarbon receptor); PARTICIPATES IN aryl hydrocarbon receptor signaling pathway; INTERACTS WITH (+)-schisandrin B; (S)-colchicine; 1,10-phenanthroline.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: ah receptor
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: Ahrem1Sage   Ahrem1Soar  
Genetic Models: SD-Nr1i2em1Sage Nr1i3em1Sage Ahrem1Sage SD-Ahrem1Sage SD-Ahrem1Soar
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2652,234,089 - 52,271,568 (-)NCBI
Rnor_6.0 Ensembl654,963,990 - 55,001,464 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0654,963,990 - 55,001,806 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0664,589,066 - 64,624,078 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4654,205,104 - 54,240,268 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1654,206,846 - 54,243,423 (-)NCBI
Celera651,391,870 - 51,429,719 (-)NCBICelera
RH 3.4 Map6350.2RGD
Cytogenetic Map6q16NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
acanthosis nigricans  (ISO)
Adult Pancreatic Cancer  (ISO)
Animal Disease Models  (ISO)
atherosclerosis  (ISO)
atopic dermatitis  (ISO)
Atrophy  (ISO)
Behcet's disease  (ISO)
Birth Weight  (ISO)
bladder calculus  (ISO)
bone resorption disease  (ISO)
Breast Neoplasms  (ISO)
Cardiomegaly  (ISO)
Chemical and Drug Induced Liver Injury  (ISO)
Chronobiology Disorders  (ISO)
colitis  (ISO)
congenital heart disease  (ISO)
congenital nystagmus  (ISO)
contact dermatitis  (ISO)
disease of cellular proliferation  (ISO)
disease of metabolism  (ISO)
Dyslipidemias  (ISO)
Endotoxemia  (ISO)
Experimental Arthritis  (ISO)
Experimental Neoplasms  (ISO)
glucose intolerance  (ISO)
Growth Disorders  (ISO)
Hepatomegaly  (ISO)
Hyperoxia  (ISO)
Hyperpigmentation  (ISO)
hypertension  (ISO)
Hypertrophy  (ISO)
Hyperventilation  (ISO)
Inflammation  (ISO)
Insulin Resistance  (ISO)
keratosis  (ISO)
Left Ventricular Hypertrophy  (ISO)
liver cirrhosis  (ISO)
liver disease  (ISO)
Liver Neoplasms  (ISO)
lung adenocarcinoma  (ISO)
Lung Injury  (ISO)
male infertility  (ISO)
Necrosis  (ISO)
Neoplasm Invasiveness  (ISO)
Neoplasm Metastasis  (ISO)
non-alcoholic fatty liver disease  (ISO)
obesity  (ISO)
pancreatic cancer  (ISO)
peanut allergy  (ISO)
pleomorphic xanthoastrocytoma  (ISO)
pneumonia  (ISO)
Prostatic Neoplasms  (ISO)
Pruritus  (ISO)
retinitis pigmentosa 85  (ISO)
rheumatoid arthritis  (ISO)
Salmonella Infections, Animal  (ISO)
silicosis  (ISO)
splenic disease  (ISO)
Splenomegaly  (ISO)
Spontaneous Abortions  (ISO)
Stomach Neoplasms  (ISO)
Tachycardia  (ISO)
Tobacco Use Disorder  (ISO)
Ureteral Neoplasms  (ISO)
vascular disease  (ISO)
Weight Gain  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-(S)-ar-turmerone  (ISO)
(+)-schisandrin B  (EXP)
(+)-taxifolin  (ISO)
(+)-Tetrandrine  (ISO)
(-)-anisomycin  (ISO)
(-)-epigallocatechin 3-gallate  (ISO)
(S)-colchicine  (EXP,ISO)
(S)-naringenin  (ISO)
(Z)-3-butylidenephthalide  (ISO)
(Z)-ligustilide  (ISO)
1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane  (ISO)
1,1,1-Trichloro-2-(4-hydroxyphenyl)-2-(4-methoxyphenyl)ethane  (ISO)
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (ISO)
1,10-phenanthroline  (EXP,ISO)
1,2,3,4,6,7,8-Heptachlorodibenzodioxin  (EXP,ISO)
1,2,3,4,6,7,8-Heptachlorodibenzofuran  (EXP,ISO)
1,2,3,4,7,8-Hexachlorodibenzodioxin  (EXP)
1,2,3,4,7,8-Hexachlorodibenzofuran  (EXP,ISO)
1,2,3,4-tetrahydroisoquinoline  (ISO)
1,2,3,6,7,8-Hexachlorodibenzodioxin  (EXP,ISO)
1,2,3,7,8-Pentachlorodibenzodioxin  (EXP,ISO)
1,2,3,7,8-Pentachlorodibenzofuran  (EXP)
1,2-benzoquinone  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
1,2-naphthoquinone  (ISO)
1,2-phenylenediamine  (ISO)
1,3-benzothiazole-2-thiol  (ISO)
1,3-dicyclohexylurea  (EXP)
1,4-benzoquinone  (ISO)
1,4-dihydroxy-2-naphthoic acid  (ISO)
1,4-naphthoquinone  (ISO)
1,7-phenanthroline  (EXP)
1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile  (ISO)
1-benzofuran  (EXP)
1-hydroxy-2-naphthoic acid  (ISO)
1-methylnaphthalene  (EXP)
1-methylphenanthrene  (EXP)
1-naphthol  (ISO)
1-naphthyl isothiocyanate  (EXP,ISO)
1-naphthylamine  (ISO)
1-nitropyrene  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
1H-indole  (ISO)
2,2',4,4',5,5'-hexabromobiphenyl  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP,ISO)
2,2',4,5-tetrachlorobiphenyl  (EXP,ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,2-(2-Chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene  (ISO)
2,3',4,4',5,5'-Hexachlorobiphenyl  (EXP,ISO)
2,3',4,4',5-Pentachlorobiphenyl  (EXP,ISO)
2,3,3',4,4',5-Hexachlorobiphenyl  (EXP,ISO)
2,3,4,3',4'-Pentachlorobiphenyl  (EXP,ISO)
2,3,4,7,8-Pentachlorodibenzofuran  (EXP,ISO)
2,3,7,8-tetrabromodibenzodioxine  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP,ISO)
2,4,6-trinitrobenzenesulfonic acid  (ISO)
2,4,6-Triphenyl-1-hexene  (ISO)
2,4-diaminotoluene  (EXP)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (EXP,ISO)
2,4-dichlorophenol  (ISO)
2,6-dimethylnaphthalene  (ISO)
2-acetamidofluorene  (ISO)
2-Amino-3-methyl-9H-pyrido[2,3-b]indole  (ISO)
2-Amino-9H-pyrido[2,3-b]indole  (ISO)
2-butan-2-yl-4-[4-[4-[4-[[2-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-1,2,4-triazol-3-one  (ISO)
2-butoxyethanol  (ISO)
2-hydroxypropanoic acid  (ISO)
2-methylnaphthalene  (EXP)
2-naphthol  (ISO)
2-nitrofluorene  (ISO)
2-tert-butylhydroquinone  (EXP,ISO)
3',5'-cyclic AMP  (EXP,ISO)
3',5'-dimethoxyflavone  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP,ISO)
3,3',4,4'-tetrachlorobiphenyl  (EXP,ISO)
3,3',5,5'-tetrabromobisphenol A  (EXP,ISO)
3,3',5-triiodo-L-thyronine  (ISO)
3,3'-Dichlorobenzidine  (EXP)
3,3'-diindolylmethane  (EXP,ISO)
3,4,5,3',4',5'-Hexachlorobiphenyl  (EXP,ISO)
3-Amino-1-methyl-5H-pyrido[4,3-b]indole  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3-methyl-3H-imidazo[4,5-f]quinolin-2-amine  (ISO)
3-methylcholanthrene  (EXP,ISO)
3-Methylchrysene  (EXP)
3-Nitrofluoranthene  (ISO)
3-Nitroperylene  (EXP)
4',5,7-trihydroxy-3'-methoxyflavone  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4,7-phenanthroline  (EXP,ISO)
4-chloro-m-cresol  (ISO)
4-nitrophenol  (EXP)
4-nonylphenol  (EXP,ISO)
4-Vinylcyclohexene  (EXP)
5-aza-2'-deoxycytidine  (ISO)
5-azacytidine  (ISO)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (EXP,ISO)
5-Nitroacenaphthene  (ISO)
6-bromoindirubin-3'-oxime  (ISO)
6-chrysenamine  (EXP,ISO)
6-Methylchrysene  (EXP)
6-Nitrochrysene  (ISO)
7,12-dimethyltetraphene  (EXP,ISO)
7-ketocholesterol  (EXP,ISO)
7-Nitrobenz[a]anthracene  (ISO)
8-Br-cAMP  (ISO)
9-Nitroanthracene  (ISO)
9H-carbazole  (EXP,ISO)
aceanthrylene  (EXP)
acenaphthene  (ISO)
Acetyleugenol  (ISO)
acetylleucyl-leucyl-norleucinal  (ISO)
acetylsalicylic acid  (EXP,ISO)
acridines  (EXP,ISO)
Actein  (ISO)
acteoside  (ISO)
actinomycin D  (ISO)
adefovir pivoxil  (ISO)
ADP  (EXP)
afimoxifene  (ISO)
aflatoxin B1  (EXP,ISO)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (EXP,ISO)
all-trans-retinol  (ISO)
alpha-naphthoflavone  (EXP,ISO)
alpha-pinene  (ISO)
alternariol  (ISO)
ammonium chloride  (EXP)
AMP-PNP  (EXP)
Androstane-3,17-diol dipropionate  (ISO)
anethole  (ISO)
angelicin  (EXP)
anilines  (ISO)
annomontine  (ISO)
anthra[1,9-cd]pyrazol-6(2H)-one  (ISO)
anthracene  (EXP,ISO)
anthraflavic acid  (ISO)
antigen  (ISO)
apigenin  (ISO)
arachidonic acid  (ISO)
Aroclor 1254  (EXP,ISO)
arsenite(3-)  (EXP,ISO)
ATP  (EXP)
atrazine  (ISO)
Aurin  (ISO)
baicalein  (ISO)
baicalin  (ISO)
benidipine  (ISO)
benzene  (ISO)
Benzo[a]fluorene  (EXP)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[a]pyrene-7,8-dione  (ISO)
benzo[b]fluoranthene  (EXP,ISO)
Benzo[b]fluorene  (EXP)
benzo[c]phenanthrene  (ISO)
benzo[e]pyrene  (EXP,ISO)
BENZO[G]CHRYSENE  (EXP)
Benzo[ghi]perylene  (EXP,ISO)
Benzo[j]fluoranthene  (EXP,ISO)
Benzo[k]fluoranthene  (EXP,ISO)
benzoates  (ISO)
benzofurans  (EXP,ISO)
benzothiazole  (ISO)
benzylamine  (ISO)
berberine  (EXP,ISO)
bergomottin  (EXP,ISO)
beta-carboline  (ISO)
beta-naphthoflavone  (EXP,ISO)
beta-pinene  (ISO)
bifenthrin  (ISO)
bilirubin IXalpha  (ISO)
biochanin A  (EXP,ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
bitertanol  (ISO)
bromobenzene  (EXP)
bucladesine  (ISO)
butylated hydroxyanisole  (ISO)
Butylbenzyl phthalate  (ISO)
C60 fullerene  (EXP)
cadmium atom  (EXP,ISO)
cadmium dichloride  (EXP,ISO)
cantharidin  (ISO)
capsaicin  (ISO)
carbamazepine  (ISO)
carbaryl  (EXP,ISO)
carbazole  (EXP,ISO)
carbendazim  (ISO)
carbon nanotube  (ISO)
Carnosol  (ISO)
carvacrol  (ISO)
carvone  (ISO)
catechol  (ISO)
chelerythrine  (ISO)
chenodeoxycholic acid  (ISO)
CHIR 99021  (ISO)
chlormequat chloride  (ISO)
chloroacetaldehyde  (ISO)
chlorohydrocarbon  (ISO)
chlorothalonil  (EXP)
chlorpromazine  (EXP)
chlorpropham  (ISO)
chlorpyrifos  (EXP,ISO)
chlorpyrifos-methyl  (ISO)
cholesterol  (ISO)
cholic acid  (ISO)
chromium atom  (ISO)
chrysazin  (ISO)
chrysene  (EXP,ISO)
chrysin  (EXP,ISO)
chrysophanol  (ISO)
cidofovir anhydrous  (ISO)
cimetidine  (ISO)
cisplatin  (ISO)
citalopram  (ISO)
clodronic acid  (ISO)
clofibrate  (EXP,ISO)
clofibric acid  (EXP)
clotrimazole  (ISO)
cobalt atom  (EXP)
cobalt dichloride  (ISO)
colforsin daropate hydrochloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) nitrate  (ISO)
copper(II) sulfate  (ISO)
crocidolite asbestos  (ISO)
Cryptotanshinone  (ISO)
CTP  (EXP)
curcumin  (ISO)
cyanidin cation  (ISO)
cycloheximide  (ISO)
Cyclopenta[cd]pyrene  (EXP)
cyclosporin A  (EXP,ISO)
Cynaropicrin  (ISO)
cypermethrin  (ISO)
cyproconazole  (EXP,ISO)
cyprodinil  (EXP,ISO)
D-glucose  (ISO)
daidzein  (ISO)
DDE  (ISO)
DDT  (ISO)
decabromodiphenyl ether  (EXP,ISO)
deoxycholic acid  (ISO)
dexamethasone  (EXP,ISO)
diazinon  (EXP)
Dibenz[a,c]anthracene  (EXP)
dibenz[a,h]anthracene  (EXP,ISO)
Dibenz[a,j]acridine  (EXP)
Dibenz[a,j]anthracene  (EXP)
dibenzo[a,l]pyrene  (EXP,ISO)
dibenzofuran  (EXP,ISO)
dibenzothiophene  (EXP)
dibutyl phthalate  (EXP,ISO)
diclofenac  (ISO)
dieldrin  (EXP,ISO)
diethofencarb  (ISO)
diethyl phthalate  (ISO)
diethylstilbestrol  (ISO)
dihydroresveratrol  (ISO)
Dihydrotanshinone I  (ISO)
Diisodecyl phthalate  (ISO)
dimethyl sulfoxide  (ISO)
dimethylarsinic acid  (ISO)
diosmin  (ISO)
dioxygen  (EXP,ISO)
diphosphoric acid  (EXP)
diuron  (EXP,ISO)
dorsomorphin  (ISO)
doxycycline  (ISO)
ellipticine  (ISO)
emodin  (ISO)
endosulfan  (EXP)
epoxiconazole  (EXP,ISO)
epoxomicin  (ISO)
Estragole  (ISO)
ethanol  (EXP,ISO)
ethylenediaminetetraacetic acid  (EXP)
eugenol  (ISO)
felodipine  (ISO)
fenofibrate  (EXP,ISO)
flavone  (ISO)
flavones  (EXP,ISO)
flavonoids  (EXP)
flavonols  (ISO)
fludioxonil  (ISO)
fluoranthene  (EXP,ISO)
fluorene  (ISO)
fluvalinate  (ISO)
folic acid  (ISO)
folpet  (ISO)
formononetin  (ISO)
fructose  (ISO)
fulvestrant  (ISO)
fumonisin B1  (EXP)
Furafylline  (ISO)
galangin  (ISO)
gallocatechin  (ISO)
gamma-hexachlorocyclohexane  (EXP)
gamma-terpinene  (ISO)
geldanamycin  (ISO)
gemfibrozil  (EXP)
genistein  (EXP,ISO)
Glu-P-1  (ISO)
Glu-P-2  (ISO)
glucose  (ISO)
glutathione  (ISO)
glyburide  (ISO)
glycitein  (ISO)
GTP  (EXP)
harman  (ISO)
harmine  (ISO)
herbimycin  (ISO)
hesperetin  (ISO)
hexachlorobenzene  (EXP,ISO)
hexadecanoic acid  (ISO)
hydrogen peroxide  (ISO)
hydroquinone  (EXP,ISO)
hyodeoxycholic acid  (ISO)
ibuprofen  (EXP)
icosanoid  (ISO)
ifosfamide  (ISO)
Indeno[1,2,3-cd]pyrene  (EXP,ISO)
indigo carmine  (ISO)
indirubin-3'-monoxime  (ISO)
indole-3-acetic acid  (ISO)
indole-3-methanol  (EXP,ISO)
indoles  (EXP,ISO)
indoxyl sulfate  (ISO)
ionomycin  (ISO)
iprodione  (EXP,ISO)
iron dextran  (ISO)
is