Ahr (aryl hydrocarbon receptor) - Rat Genome Database

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Gene: Ahr (aryl hydrocarbon receptor) Rattus norvegicus
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Symbol: Ahr
Name: aryl hydrocarbon receptor
RGD ID: 2074
Description: Enables nuclear receptor activity and toxic substance binding activity. Involved in several processes, including cellular response to organic cyclic compound; negative regulation of alkaline phosphatase activity; and regulation of cellular macromolecule biosynthetic process. Located in cytosol and nucleus. Human ortholog(s) of this gene implicated in retinitis pigmentosa 85. Orthologous to human AHR (aryl hydrocarbon receptor); PARTICIPATES IN aryl hydrocarbon receptor signaling pathway; INTERACTS WITH (+)-schisandrin B; (S)-colchicine; 1,10-phenanthroline.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: ah receptor
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: Ahrem1Sage   Ahrem1Soar   Ahrem2Sage  
Genetic Models: SD-Ahrem2Sage SD-Nr1i2em1Sage Nr1i3em1Sage Ahrem1Sage SD-Ahrem1Sage SD-Ahrem1Soar
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2652,234,089 - 52,271,568 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl652,234,089 - 52,271,568 (-)Ensembl
Rnor_6.0654,963,990 - 55,001,806 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl654,963,990 - 55,001,464 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0664,589,066 - 64,624,078 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4654,205,104 - 54,240,268 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1654,206,846 - 54,243,423 (-)NCBI
Celera651,391,870 - 51,429,719 (-)NCBICelera
RH 3.4 Map6350.2RGD
Cytogenetic Map6q16NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
acanthosis nigricans  (ISO)
Adult Pancreatic Cancer  (ISO)
Animal Disease Models  (ISO)
atherosclerosis  (ISO)
atopic dermatitis  (ISO)
Atrophy  (ISO)
Behcet's disease  (ISO)
Birth Weight  (ISO)
bladder calculus  (ISO)
bone resorption disease  (ISO)
Breast Neoplasms  (ISO)
Cardiomegaly  (ISO)
Chemical and Drug Induced Liver Injury  (ISO)
Chronobiology Disorders  (ISO)
colitis  (ISO)
congenital heart disease  (ISO)
congenital nystagmus  (ISO)
contact dermatitis  (ISO)
disease of cellular proliferation  (ISO)
disease of metabolism  (ISO)
Dyslipidemias  (ISO)
Endotoxemia  (ISO)
Experimental Arthritis  (ISO)
Experimental Neoplasms  (ISO)
glucose intolerance  (ISO)
Growth Disorders  (ISO)
Hepatomegaly  (ISO)
Hyperoxia  (ISO)
Hyperpigmentation  (ISO)
hypertension  (ISO)
Hypertrophy  (ISO)
Hyperventilation  (ISO)
Inflammation  (ISO)
Insulin Resistance  (ISO)
keratosis  (ISO)
Left Ventricular Hypertrophy  (ISO)
liver cirrhosis  (ISO)
liver disease  (ISO)
Liver Neoplasms  (ISO)
lung adenocarcinoma  (ISO)
Lung Injury  (ISO)
male infertility  (ISO)
Necrosis  (ISO)
Neoplasm Invasiveness  (ISO)
Neoplasm Metastasis  (ISO)
non-alcoholic fatty liver disease  (ISO)
obesity  (ISO)
pancreatic cancer  (ISO)
peanut allergy  (ISO)
pleomorphic xanthoastrocytoma  (ISO)
pneumonia  (ISO)
Prostatic Neoplasms  (ISO)
Pruritus  (ISO)
retinitis pigmentosa 85  (ISO)
rheumatoid arthritis  (ISO)
Salmonella Infections, Animal  (ISO)
silicosis  (ISO)
splenic disease  (ISO)
Splenomegaly  (ISO)
Spontaneous Abortions  (ISO)
Stomach Neoplasms  (ISO)
Tachycardia  (ISO)
Tobacco Use Disorder  (ISO)
Ureteral Neoplasms  (ISO)
vascular disease  (ISO)
Weight Gain  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-(S)-ar-turmerone  (ISO)
(+)-schisandrin B  (EXP)
(+)-taxifolin  (ISO)
(+)-Tetrandrine  (ISO)
(-)-anisomycin  (ISO)
(-)-epigallocatechin 3-gallate  (ISO)
(S)-colchicine  (EXP,ISO)
(S)-naringenin  (ISO)
(S)-nicotine  (ISO)
(Z)-3-butylidenephthalide  (ISO)
(Z)-ligustilide  (ISO)
1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane  (ISO)
1,1,1-Trichloro-2-(4-hydroxyphenyl)-2-(4-methoxyphenyl)ethane  (ISO)
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (ISO)
1,10-phenanthroline  (EXP,ISO)
1,2,3,4,6,7,8-Heptachlorodibenzodioxin  (EXP,ISO)
1,2,3,4,6,7,8-Heptachlorodibenzofuran  (EXP,ISO)
1,2,3,4,7,8-Hexachlorodibenzodioxin  (EXP)
1,2,3,4,7,8-Hexachlorodibenzofuran  (EXP,ISO)
1,2,3,4-tetrahydroisoquinoline  (ISO)
1,2,3,6,7,8-Hexachlorodibenzodioxin  (EXP,ISO)
1,2,3,7,8-Pentachlorodibenzodioxin  (EXP,ISO)
1,2,3,7,8-Pentachlorodibenzofuran  (EXP)
1,2-benzoquinone  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
1,2-naphthoquinone  (ISO)
1,2-phenylenediamine  (ISO)
1,3-benzothiazole-2-thiol  (ISO)
1,3-dicyclohexylurea  (EXP)
1,4-benzoquinone  (ISO)
1,4-dihydroxy-2-naphthoic acid  (ISO)
1,4-naphthoquinone  (ISO)
1,7-phenanthroline  (EXP)
1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile  (ISO)
1-benzofuran  (EXP)
1-hydroxy-2-naphthoic acid  (ISO)
1-Methylfluorene  (EXP)
1-methylnaphthalene  (EXP)
1-methylphenanthrene  (EXP)
1-naphthol  (ISO)
1-naphthyl isothiocyanate  (EXP,ISO)
1-naphthylamine  (ISO)
1-nitropyrene  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
1H-indole  (ISO)
2,2',4,4',5,5'-hexabromobiphenyl  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP,ISO)
2,2',4,5-tetrachlorobiphenyl  (EXP,ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,2-(2-Chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene  (ISO)
2,3',4,4',5,5'-Hexachlorobiphenyl  (EXP,ISO)
2,3',4,4',5-Pentachlorobiphenyl  (EXP,ISO)
2,3,3',4,4',5-Hexachlorobiphenyl  (EXP,ISO)
2,3,4,3',4'-Pentachlorobiphenyl  (EXP,ISO)
2,3,4,7,8-Pentachlorodibenzofuran  (EXP,ISO)
2,3,7,8-tetrabromodibenzodioxine  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP,ISO)
2,4,6-trinitrobenzenesulfonic acid  (ISO)
2,4,6-Triphenyl-1-hexene  (ISO)
2,4-diaminotoluene  (EXP)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (EXP,ISO)
2,4-dichlorophenol  (ISO)
2,6-dimethylnaphthalene  (ISO)
2-acetamidofluorene  (ISO)
2-Amino-3-methyl-9H-pyrido[2,3-b]indole  (ISO)
2-Amino-9H-pyrido[2,3-b]indole  (ISO)
2-butan-2-yl-4-[4-[4-[4-[[2-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-1,2,4-triazol-3-one  (ISO)
2-butoxyethanol  (ISO)
2-hydroxypropanoic acid  (ISO)
2-methylnaphthalene  (EXP)
2-naphthol  (ISO)
2-nitrofluorene  (ISO)
2-tert-butylhydroquinone  (EXP,ISO)
3',5'-cyclic AMP  (EXP,ISO)
3',5'-dimethoxyflavone  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP,ISO)
3,3',4,4'-tetrachlorobiphenyl  (EXP,ISO)
3,3',5,5'-tetrabromobisphenol A  (EXP,ISO)
3,3',5-triiodo-L-thyronine  (ISO)
3,3'-Dichlorobenzidine  (EXP)
3,3'-diindolylmethane  (EXP,ISO)
3,4,5,3',4',5'-Hexachlorobiphenyl  (EXP,ISO)
3-Amino-1-methyl-5H-pyrido[4,3-b]indole  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3-methyl-3H-imidazo[4,5-f]quinolin-2-amine  (ISO)
3-methylcholanthrene  (EXP,ISO)
3-Methylchrysene  (EXP)
3-Nitrobenzanthrone  (ISO)
3-Nitrofluoranthene  (ISO)
3-Nitroperylene  (EXP)
4',5,7-trihydroxy-3'-methoxyflavone  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4,7-phenanthroline  (EXP,ISO)
4-chloro-m-cresol  (ISO)
4-nitrophenol  (EXP)
4-nonylphenol  (EXP,ISO)
4-Vinylcyclohexene  (EXP)
5-aza-2'-deoxycytidine  (ISO)
5-azacytidine  (ISO)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (EXP,ISO)
5-Nitroacenaphthene  (ISO)
6-bromoindirubin-3'-oxime  (ISO)
6-chrysenamine  (EXP,ISO)
6-Methylchrysene  (EXP)
6-Nitrochrysene  (ISO)
7,12-dimethyltetraphene  (EXP,ISO)
7-ketocholesterol  (EXP,ISO)
7-Nitrobenz[a]anthracene  (ISO)
8-Br-cAMP  (ISO)
9-Nitroanthracene  (ISO)
9H-carbazole  (EXP,ISO)
aceanthrylene  (EXP)
acenaphthene  (ISO)
Acetyleugenol  (ISO)
acetylleucyl-leucyl-norleucinal  (ISO)
acetylsalicylic acid  (EXP,ISO)
acridines  (EXP,ISO)
Actein  (ISO)
acteoside  (ISO)
actinomycin D  (ISO)
adefovir pivoxil  (ISO)
ADP  (EXP)
afimoxifene  (ISO)
aflatoxin B1  (EXP,ISO)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (EXP,ISO)
all-trans-retinol  (ISO)
alpha-naphthoflavone  (EXP,ISO)
alpha-pinene  (ISO)
alternariol  (ISO)
ammonium chloride  (EXP)
AMP-PNP  (EXP)
Androstane-3,17-diol dipropionate  (ISO)
anethole  (ISO)
angelicin  (EXP)
anilines  (ISO)
annomontine  (ISO)
anthra[1,9-cd]pyrazol-6(2H)-one  (ISO)
anthracene  (EXP,ISO)
anthraflavic acid  (ISO)
antigen  (ISO)
apigenin  (ISO)
arachidonic acid  (ISO)
Aroclor 1254  (EXP,ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (EXP,ISO)
ATP  (EXP)
atrazine  (ISO)
Aurin  (ISO)
baicalein  (ISO)
baicalin  (ISO)
benidipine  (ISO)
benzene  (ISO)
Benzo[a]fluorene  (EXP)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[a]pyrene-7,8-dione  (ISO)
benzo[b]fluoranthene  (EXP,ISO)
Benzo[b]fluorene  (EXP)
benzo[c]phenanthrene  (ISO)
benzo[e]pyrene  (EXP,ISO)
BENZO[G]CHRYSENE  (EXP)
Benzo[ghi]perylene  (EXP,ISO)
Benzo[j]fluoranthene  (EXP,ISO)
Benzo[k]fluoranthene  (EXP,ISO)
benzoates  (ISO)
benzofurans  (EXP,ISO)
benzothiazole  (ISO)
benzylamine  (ISO)
berberine  (EXP,ISO)
bergomottin  (EXP,ISO)
beta-carboline  (ISO)
beta-hexachlorocyclohexane  (ISO)
beta-naphthoflavone  (EXP,ISO)
beta-pinene  (ISO)
betalain  (ISO)
bifenthrin  (ISO)
bilirubin IXalpha  (ISO)
biochanin A  (EXP,ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
bitertanol  (ISO)
bromobenzene  (EXP)
bucladesine  (ISO)
butylated hydroxyanisole  (ISO)