Strain Report - Rat Genome Database

Name: F344- Il2rg em1Kyo
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Strain Registration

General

Strain: F344-Il2rg^em1Kyo

Symbol:

F344-Il2rg^em1Kyo

Strain:

F344-Il2rg^em1

Substrain:

Kyo

RGD ID:

9685625

Citation ID:

RRID:RGD_9685625

Ontology ID:

RS:0003849

Alleles:

Il2rg^em1Kyo

Previously known as:

X-SCID; NBRP Rat No: 0585; F344-Il2rgem1Kyo

Type:

mutant

Source:

National BioResource Project for the Rat in Japan

Origin:

The strain having a zinc finger nuclease-induced 660-bp deletion mutation in Il2rg gene shows severe combined immunodeficiency and grows normally under SPF condition.

Coat Color:

albino

Inbred Generations:

Last Known Status:

Cryopreserved Sperm (as of 2017-03-27)

Research Usage

Immunology

Position

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	X	66,395,330 - 66,399,026	RGD_MAPPER_PIPELINE	mRatBN7.2
Rnor_6.0	X	71,165,378 - 71,169,078	RGD_MAPPER_PIPELINE	Rnor6.0
Rnor_5.0	X	72,017,856 - 72,021,516	RGD_MAPPER_PIPELINE	Rnor5.0
RGSC_v3.4	X	89,342,055 - 89,345,715	RGD_MAPPER_PIPELINE	RGSC3.4

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

combined T cell and B cell immunodeficiency (IMP)

X-linked severe combined immunodeficiency (IMP)

References

References - curated

#	Reference Title	Reference Citation
1.	Generation of knockout rats with X-linked severe combined immunodeficiency (X-SCID) using zinc-finger nucleases.	Mashimo T, etal., PLoS One. 2010 Jan 25;5(1):e8870.
2.	Strains registered by the National Bio Resource Project for the Rat in Japan	Personal Communication with NBRP
3.	RGD Strain RSO annotation pipeline	RGD Automated Pipelines

Region

Additional Information

Nomenclature History

Date	Current Symbol	Previous Symbol	Description	Reference	Status
2015-07-14	F344-Il2rg^em1Kyo	F344-Il2rg^em1Kyo	Name updated	68913	APPROVED
2015-07-14	F344-Il2rg^em1Kyo	F344-Il2rg^em1Kyo	Name updated	68913	APPROVED
2015-01-20	F344-Il2rg^em1Kyo	F344-Il2rg^em1Kyo	Name updated	68913	APPROVED
2015-01-20	F344-Il2rg^em1Kyo	F344-Il2rg^em1Kyo	Name updated	68913	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Strain: F344-Il2rgem1Kyo

Strain: F344-Il2rg^em1Kyo