Gene: Atp7b (ATPase copper transporting beta) Rattus norvegicus
Symbol: Atp7b
Name: ATPase copper transporting beta
Description: ENCODES a protein that exhibits copper ion binding; copper ion transmembrane transporter activity; zinc ion binding; INVOLVED IN cellular response to copper ion; cellular response to manganese ion; circadian rhythm; PARTICIPATES IN cisplatin drug pathway; ASSOCIATED WITH Hepatolenticular Degeneration; Breast Neoplasms (ortholog); Carcinoma (ortholog); FOUND IN apical part of cell; basolateral plasma membrane; bicellular tight junction; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; 6-propyl-2-thiouracil
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: ATPase Cu++ transporting beta polypeptide (same as Wilson disease); ATPase, Cu++ transporting, beta polypeptide; ATPase, Cu++ transporting, beta polypeptide (same as Wilson disease); copper pump 2; copper-transporting ATPase 2; Hts; PINA; PINA gene, promoter; pineal night-specific ATPase; Wd; wilson disease-associated protein homolog
Homo sapiens (human) : ATP7B (ATPase copper transporting beta)  HGNC  Alliance
Mus musculus (house mouse) : Atp7b (ATPase, Cu++ transporting, beta polypeptide)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Atp7b (ATPase copper transporting beta)
Pan paniscus (bonobo/pygmy chimpanzee) : ATP7B (ATPase copper transporting beta)
Canis lupus familiaris (dog) : ATP7B (ATPase copper transporting beta)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Atp7b (ATPase copper transporting beta)
more info ...
Allele / Splice: Atp7bhts  
Genetic Models: LEC/Hok
Is Marker For: Strains:   LEC/Tj   WKAH.LEC-Atp7bhts/Tj  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01674,865,516 - 74,944,935 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01674,495,179 - 74,575,822 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41674,607,988 - 74,680,080 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11674,608,239 - 74,679,614 (+)NCBI
Celera1667,837,288 - 67,908,140 (+)NCBICelera
Cytogenetic Map16q12.5NCBI
RH 3.4 Map16664.21RGD
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Related Rat Strains
Genetic Models
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Atp7b
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2180
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2018-03-13
Status: ACTIVE