Arunc2 QTL Report (Rattus norvegicus)

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General

QTL: Arunc2 (Aerobic running capacity QTL 2) Rattus norvegicus

Symbol:

Arunc2

Name:

Aerobic running capacity QTL 2

Also known as:

Arc2

Trait:

exercise endurance trait (VT:0002332)

Measurement Type:

maximum distance run on treadmill (CMO:0001406)

LOD Score:

2.9

P Value:

Not Available

Variance:

Not Available

Inheritance Type:

dominant

Position

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_6.0	16	73,219,638 - 80,115,794	RGD_MAPPER_PIPELINE	Rnor6.0
Rnor_5.0	16	72,850,762 - 79,690,408	RGD	Rnor5.0
RGSC_v3.4	16	73,394,189 - 79,850,195	RGD	RGSC3.4
RGSC_v3.1	16	73,394,454 - 79,850,460	RGD

Cross Type:

Not Available

Strains Crossed:

COP/OlaHsd DA/OlaHsd

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation (Toggle Annotation Detail/Summary View)

Candidate Gene Status

	Acsl1 is a candidate Gene for Arunc2
	Irs2 is a candidate Gene for Arunc2
	Pdlim3 is a candidate Gene for Arunc2
	Ppif is a candidate Gene for Arunc2
	Tm2d2 is a candidate Gene for Arunc2

Phenotype Annotations

Mammalian Phenotype

Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
decreased aerobic running capacity		IAGP		619535		RGD
increased aerobic running capacity		QTM		619535		RGD

Experimental Data Annotations

Clinical Measurement

Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
maximum distance run on treadmill		IDA		619535		RGD

Experimental Condition

Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
running on inclined treadmill		IDA		619535		RGD

Measurement Method

Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
treadmill method with electric shock source and automated tracking		IDA		619535		RGD

Rat Strain

Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
COP/OlaHsd		IEA		619535		RGD
DA/OlaHsd		IEA		619535		RGD

Vertebrate Trait

Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
exercise endurance trait		IDA		619535		RGD

Phenotype Annotations

Mammalian Phenotype

decreased aerobic running capacity (IAGP)

increased aerobic running capacity (QTM)

Experimental Data Annotations

Clinical Measurement

maximum distance run on treadmill (IDA)

Experimental Condition

running on inclined treadmill (IDA)

Measurement Method

treadmill method with electric shock source and automated tracking (IDA)

Rat Strain

	COP/OlaHsd (IEA)
	DA/OlaHsd (IEA)

Vertebrate Trait

exercise endurance trait (IDA)

References - curated

1.	Lee SJ, etal., Physiol Genomics 2005 Jul 20;.
2.	Ways JA, etal., Genomics 2002 Jul;80(1):13-20.

Related QTLs

Related QTL	Description	Reference
Arunc3	interacts with	RGD:619535

Region

Genes in Region (Rnor_6.0)

The following Genes overlap with this region.

RGD ID	Symbol	Name	Chr	Start	Stop	Species
2180	Atp7b	ATPase copper transporting beta	16	74865516	74944935	Rat
3342	Plat	plasminogen activator, tissue type	16	74098263	74122897	Rat
3363	Polb	DNA polymerase beta	16	74237001	74260272	Rat
3699	Slc20a2	solute carrier family 20 member 2	16	74318287	74408030	Rat
70969	Ap3m2	adaptor related protein complex 3 subunit mu 2	16	74075842	74091230	Rat
619943	Defb1	defensin beta 1	16	75294385	75309127	Rat
619944	Defb4	defensin beta 4	16	75634598	75637789	Rat
620224	Dlgap2	DLG associated protein 2	16	79872238	80596977	Rat
621074	Sfrp1	secreted frizzled-related protein 1	16	73372007	73410777	Rat
621375	Ikbkb	inhibitor of nuclear factor kappa B kinase subunit beta	16	74177233	74230809	Rat
621577	Vdac3	voltage-dependent anion channel 3	16	74292466	74308910	Rat
621861	Angpt2	angiopoietin 2	16	75966480	76016147	Rat
628905	Spag11a	sperm associated antigen 11A	16	75666439	75668180	Rat
631437	Myom2	myomesin 2	16	79587136	79672871	Rat
727857	Np4	defensin NP-4 precursor	16	75478548	75481146	Rat
727951	Defa5	defensin alpha 5	16	75338050	75340401	Rat
1304852	Defa24	defensin alpha 24	16	75345086	75346122	Rat
1304892	Kat6a	lysine acetyltransferase 6A	16	73942669	74020750	Rat
1305103	Csmd1	CUB and Sushi multiple domains 1	16	77152823	78850222	Rat
1305825	Tpte2	transmembrane phosphoinositide 3-phosphatase and tensin homolog 2	16	74552859	74662194	Rat
1306405	Agpat5	1-acylglycerol-3-phosphate O-acyltransferase 5	16	75812837	75855996	Rat
1306998	Thsd1	thrombospondin type 1 domain containing 1	16	74680621	74712368	Rat
1307397	Gins4	GINS complex subunit 4	16	73584412	73596808	Rat
1307419	Nek3	NIMA-related kinase 3	16	74781371	74806567	Rat
1307668	Mrps31	mitochondrial ribosomal protein S31	16	74467874	74504834	Rat
1309620	Ank1	ankyrin 1	16	73681422	73912605	Rat
1309754	Vps36	vacuolar protein sorting 36 homolog	16	74719642	74743921	Rat
1310520	Gpat4	glycerol-3-phosphate acyltransferase 4	16	73615949	73649769	Rat
1311488	Slc25a15	solute carrier family 25 member 15	16	74505318	74554523	Rat
1311631	Ckap2	cytoskeleton associated protein 2	16	74752655	74779184	Rat
1359335	Xkr5	XK related 5	16	75744786	75762694	Rat
1359518	Cln8	CLN8, transmembrane ER and ERGIC protein	16	79828321	79838212	Rat
1359725	Golga7	golgin A7	16	73564172	73579389	Rat
1559811	Ccdc70	coiled-coil domain containing 70	16	74958897	74963925	Rat
1559883	Defb13	defensin beta 13	16	75027131	75028977	Rat
1560529	Defa7	defensin alpha 7	16	75414786	75415555	Rat
1560642	Mcph1	microcephalin 1	16	75904087	76110624	Rat
1560790	Defb37	defensin beta 37	16	75083173	75094963	Rat
1561378	Defb14	defensin beta 14	16	75647523	75650913	Rat
1561398	Defal1	defensin alpha-like 1	16	75366925	75367985	Rat
1561801	Defb38	defensin beta 38	16	75058572	75061804	Rat
1562293	Defa6	defensin alpha 6	16	75400781	75401655	Rat
1562518	Defb10	defensin beta 10	16	75198178	75208230	Rat
1562959	Defb33	defensin beta 33	16	75578681	75585475	Rat
1563061	Defb15	defensin beta 15	16	75105290	75107931	Rat
1563138	Defb9	defensin beta 9	16	75176307	75179090	Rat
1563172	Dkk4	dickkopf WNT signaling pathway inhibitor 4	16	74260551	74264142	Rat
1563282	Defb50	defensin beta 50	16	75249704	75262002	Rat
1563576	Kbtbd11	kelch repeat and BTB domain containing 11	16	79696395	79716129	Rat
1563630	Defb5	defensin beta 5	16	75597323	75599483	Rat
1563712	Defb40	defensin beta 40	16	75702347	75705489	Rat
1563816	Defb39	defensin beta 39	16	75042516	75046320	Rat
1564032	Defb11	defensin beta 11	16	75146200	75156555	Rat
1564555	Defa9	defensin alpha 9	16	75465710	75466604	Rat
1564725	Alg11	ALG11, alpha-1,2-mannosyltransferase	16	74854007	74866096	Rat
1564782	Defb51	defensin beta 51	16	75554852	75558974	Rat
1564879	Defb12	defensin beta 12	16	75118002	75120417	Rat
1565043	Arhgef10	Rho guanine nucleotide exchange factor 10	16	79725629	79817065	Rat
1565394	Defb52	defensin beta 52	16	75572014	75574546	Rat
1566065	Defa8	defensin alpha 8	16	75428675	75429568	Rat
1566125	Defb2	defensin beta 2	16	75227468	75241303	Rat
1583286	LOC685012	similar to heterogeneous nuclear ribonucleoprotein A3	16	73470967	73471996	Rat
1587186	Defa11	defensin alpha 11	16	75517421	75519605	Rat
1587187	Defa10	defensin alpha 10	16	75498236	75499012	Rat
1589653	RatNP-3b	defensin RatNP-3 precursor	16	75528348	75530511	Rat
1590228	LOC685740	hypothetical protein LOC685740	16	75053430	75054032	Rat
1590848	LOC364636	similar to myc induced nuclear antigen	16	79557341	79559145	Rat
1593817	Nek5	NIMA-related kinase 5	16	74809513	74851895	Rat
1597780	Nkx6-3	NK6 homeobox 3	16	73665269	73670482	Rat
2318111	Fam90a1	family with sequence similarity 90, member A1	16	75001033	75016173	Rat
2318364	Smim19	small integral membrane protein 19	16	74408085	74422070	Rat
2323116	Map1lc3b2	microtubule-associated protein 1 light chain 3 beta 2	16	75864144	75874567	Rat
2323322	LOC100359819	hypothetical protein LOC100359819	16	75458511	75459338	Rat
2323473	LOC100359767	hypothetical LOC100359767	16	75387296	75389923	Rat
2324475	Spag11bl	sperm associated antigen 11b-like	16	75145234	75148750	Rat
6485037	LOC100912990	beta-defensin 12-like	16	75109946	75110960	Rat
6498623	LOC100910418	tissue-type plasminogen activator-like	16	73745767	73763198	Rat
7505881	LOC102550761	uncharacterized LOC102550761	16	78863101	78915311	Rat
7513826	LOC102547381	uncharacterized LOC102547381	16	79721169	79725984	Rat
7516097	LOC102551088	uncharacterized LOC102551088	16	74392359	74393752	Rat
7524089	LOC102551219	uncharacterized LOC102551219	16	79816729	79817535	Rat
7539166	LOC102555020	glyceraldehyde-3-phosphate dehydrogenase-like	16	73724106	73725109	Rat
7550023	LOC102557538	uncharacterized LOC102557538	16	79732541	79741119	Rat
7561455	LOC102551149	uncharacterized LOC102551149	16	79706450	79711937	Rat
7665195	LOC102556951	uncharacterized LOC102556951	16	74071372	74075115	Rat
7666555	LOC102551183	uncharacterized LOC102551183	16	74985929	74987186	Rat
7690544	LOC102550986	serine/arginine repetitive matrix protein 1-like	16	74290286	74293169	Rat
7700141	LOC102550919	uncharacterized LOC102550919	16	79449071	79480307	Rat
7709651	LOC102551089	uncharacterized LOC102551089	16	79589592	79591704	Rat
7711557	LOC102550098	activated RNA polymerase II transcriptional coactivator p15-like	16	74650654	74651244	Rat
7712656	LOC102555283	alpha-defensin 24-like	16	75422266	75422380	Rat
7713472	LOC102549912	uncharacterized LOC102549912	16	74390750	74392384	Rat
9076410	LOC103693993	uncharacterized LOC103693993	16	73851530	73855207	Rat
9241721	LOC103693996	uncharacterized LOC103693996	16	75769426	75800150	Rat
9335848	LOC103693994	uncharacterized LOC103693994	16	73979717	73980664	Rat
9377306	LOC103693995	uncharacterized LOC103693995	16	74078195	74080929	Rat
9436659	LOC103690227	uncharacterized LOC103690227	16	79530624	79540622	Rat
9438733	LOC103693992	uncharacterized LOC103693992	16	73874689	73880778	Rat
11367158	LOC108348424	uncharacterized LOC108348424	16	76708157	76772854	Rat
11368550	LOC108348426	uncharacterized LOC108348426	16	77130114	77138640	Rat
11378360	LOC108353108	alpha-defensin 9-like	16	75394291	75394630	Rat
11403925	LOC108353087	cyclin-dependent kinase 4 pseudogene	16	78148129	78149108	Rat
11405023	LOC108353085	uncharacterized LOC108353085	16	74944232	74945964	Rat
11405117	LOC108348421	uncharacterized LOC108348421	16	74181050	74182023	Rat
11426526	LOC108348420	uncharacterized LOC108348420	16	73634326	73636348	Rat
11448278	LOC108348292	glyceraldehyde-3-phosphate dehydrogenase pseudogene	16	74144311	74145318	Rat
11452962	LOC108348423	uncharacterized LOC108348423	16	76137896	76143472	Rat
11498719	LOC108348427	heterogeneous nuclear ribonucleoprotein A3 pseudogene	16	79618652	79621247	Rat

Markers in Region (Rnor_6.0)

The following Markers overlap with this region.

RGD ID	Symbol	Expected Size	Chr	Start	Stop	Species	Match
35553	D16Rat16	172	16	76111887	76112058	Rat	region
37786	D16Rat25	141	16	75676362	75676500	Rat	region
36608	D16Rat48	150	16	80115641	80115794	Rat	region
34959	D16Rat14	162	16	75594973	75595106	Rat	region
35158	D16Rat13	157	16	78172050	78172206	Rat	region
39822	D16Rat94	227	16	78460020	78460246	Rat	region
40632	D16Rat57	228	16	73627094	73627313	Rat	region
39288	D16Rat37	214	16	75838775	75839000	Rat	region
42016	D16Arb2	72	16	76226167	76226242	Rat	region
41324	D16Rat55	166	16	76667628	76667805	Rat	region
42412	D16Rat130	232	16	78912076	78912307	Rat	region
40796	D16Rat56	221	16	73796479	73796715	Rat	region
60130	D16Got77	298	16	74815165	74815462	Rat	region
60131	D16Got81	111	16	77542415	77542522	Rat	region
45384	D16Got76	112	16	74233091	74233202	Rat	region
45385	D16Got75	200	16	75304320	75304516	Rat	region
45386	D16Got92	167	16	74173546	74173712	Rat	region
45388	D16Got78	185	16	76781834	76782018	Rat	region
45389	D16Got79	228	16	77173432	77173659	Rat	region
45390	D16Got80	93	16	76876207	76876299	Rat	region
45390	D16Got80	93	16	76480617	76480709	Rat	region
45391	D16Got82	213	16	78746085	78746297	Rat	region
45395	D16Got93	175	16	79605649	79605797	Rat	region
45397	D16Got90	124	16	79343020	79343142	Rat	region
625825	D16Got74	204	16	74233090	74233293	Rat	region
66391	D16Mco6	364	16	74173486	74173858	Rat	region
1628156	D16Wox27	182	16	75479492	75479673	Rat	region
1628354	D16Got119	129	16	76172394	76172522	Rat	region
1639032	D16Cebr2	283	16	75314962	75315244	Rat	region
1635835	D16Ulb1	174	16	76177541	76177714	Rat	region
1637695	D16Wox28	200	16	75529317	75529516	Rat	region
5038832	RH127358	207	16	74308671	74308877	Rat	region
5033913	RH140593	200	16	75825484	75825682	Rat	region
5033913	RH140593	200	16	75714713	75714911	Rat	region
5026022	RH130609	180	16	74400368	74400547	Rat	region
5026052	RH130718	198	16	74261984	74262181	Rat	region
5031422	AU048376	248	16	76106388	76106635	Rat	region
5034189	RH141704	200	16	73674719	73674918	Rat	region
5029333	RH144398	122	16	73650323	73650444	Rat	region
5032685	RH134919	189	16	77597072	77597260	Rat	region
5027355	AU041707	101	16	73649618	73649718	Rat	region
5030073	BE098027	158	16	79588971	79589128	Rat	region
5032917	RH136959	152	16	75813089	75813240	Rat	region
5033175	RH137859	166	16	74820783	74820948	Rat	region
5033213	RH137999	204	16	77460381	77460584	Rat	region
5033363	RH138560	209	16	74851511	74851719	Rat	region
5025532	RH128687	217	16	74318386	74318602	Rat	region
5030887	BF399189	131	16	76018464	76018594	Rat	region
5051849	RH94694	190	16	74943878	74944067	Rat	region
5055883	RH144058	228	16	75900934	75901161	Rat	region
5056097	RH144181	232	16	78443167	78443398	Rat	region
5058748	BF387021	181	16	75813978	75814163	Rat	region
5059870	BE103463	155	16	74778690	74778844	Rat	region
5059166	BE102937	206	16	77148987	77149192	Rat	region
5053641	RH142766	173	16	75813713	75813885	Rat	region
5053393	RH142622	191	16	76110212	76110402	Rat	region
5043434	RH130023	184	16	74719325	74719508	Rat	region
5045330	RH131116	185	16	79725761	79725945	Rat	region
5041830	RH129083	180	16	75811476	75811655	Rat	region
5048704	RH133057	197	16	74092885	74093081	Rat	region
5045560	RH131248	203	16	74230158	74230360	Rat	region
5047772	RH132520	194	16	79587213	79587406	Rat	region
5047176	RH132177	185	16	74071521	74071705	Rat	region
5039446	RH127710	219	16	79828432	79828650	Rat	region
5041924	RH129137	199	16	76015918	76016113	Rat	region
5048500	RH132939	217	16	73651842	73652060	Rat	region
5042276	RH129341	193	16	73649521	73649713	Rat	region
5042310	RH129360	185	16	76015899	76016080	Rat	region
5042238	RH129319	181	16	74856105	74856285	Rat	region
7191237	Sfrp1	779	16	73374339	73375117	Rat	region
5040288	RH128197	215	16	74098404	74098618	Rat	region
5043692	RH130172	182	16	74553074	74553255	Rat	region
5072252	RH136741	123	16	79739746	79739868	Rat	region
5076984	RH139492	211	16	75809251	75809461	Rat	region
5075874	RH138847	158	16	74541976	74542134	Rat	region
5075874	RH138847	158	16	74516186	74516344	Rat	region
5074970	RH138324	137	16	80087458	80087594	Rat	region
5076136	RH139000	127	16	73590291	73590417	Rat	region
5075614	RH138696	135	16	74227651	74227785	Rat	region
5079600	RH141094	181	16	73373449	73373629	Rat	region
5077790	RH139961	187	16	74230558	74230744	Rat	region
5077584	RH139840	213	16	74421801	74422013	Rat	region
5079856	RH141243	202	16	73372158	73372359	Rat	region
5080018	RH141335	182	16	73596529	73596710	Rat	region
5080026	RH141340	194	16	74094593	74094786	Rat	region
5078138	RH140165	205	16	74806252	74806456	Rat	region
5078416	RH140329	135	16	75809251	75809385	Rat	region
5079090	RH140730	227	16	73944127	73944353	Rat	region
5070772	RH134696	188	16	75762299	75762486	Rat	region
5080234	RH141462	198	16	74717478	74717675	Rat	region
5073358	RH137390	175	16	74345480	74345654	Rat	region
5073536	RH137493	190	16	73374394	73374593	Rat	region
5070650	RH134625	214	16	74554264	74554477	Rat	region
5071596	RH135173	210	16	73376095	73376304	Rat	region
5071812	RH135299	204	16	74857731	74857934	Rat	region
5072042	RH135431	184	16	73373779	73373972	Rat	region
5074330	RH137954	140	16	74097979	74098118	Rat	region
5071910	RH135355	193	16	74717295	74717487	Rat	region
5065054	BF405594	173	16	77825162	77825334	Rat	region
5067016	AU048015	155	16	76887535	76887689	Rat	region
5067016	AU048015	155	16	76817960	76818114	Rat	region
5067422	AU047758	118	16	74044407	74044524	Rat	region
5070105	RH94475	173	16	74098588	74098760	Rat	region
5069198	AU046655	270	16	77909201	77909464	Rat	region
5069198	AU046655	270	16	77909201	77909422	Rat	region
5065268	BE121319	155	16	75856795	75856950	Rat	region
5062226	BE106374	150	16	77156688	77156837	Rat	region
5060980	BF389634	175	16	74485980	74486154	Rat	region
5061994	BE112434	180	16	74554298	74554477	Rat	region
5060640	BE098786	160	16	74498819	74498978	Rat	region
5064258	BE120928	163	16	74123127	74123289	Rat	region
5064258	BE120928	163	16	73745362	73745524	Rat	region
5064812	BF405139	250	16	75956427	75956676	Rat	region
5082449	BE119431	162	16	75903263	75903424	Rat	region
5087644	PMC96815P1	140	16	75294492	75294631	Rat	region
5087648	PMC96815P3	175	16	75528392	75528566	Rat	region
5087652	PMC96815P5	123	16	75294512	75294634	Rat	region
5089263	AU049052	249	16	77079474	77079722	Rat	region
5089567	AU049232	225	16	77104554	77104778	Rat	region
5087646	PMC96815P2	178	16	75634615	75634792	Rat	region
5087650	PMC96815P4	123	16	75478603	75478725	Rat	region
5085461	AW533825	158	16	79774144	79774301	Rat	region
5080782	RH141778	186	16	75967825	75968010	Rat	region
5082911	BF390395	152	16	75759788	75759939	Rat	region
5083137	BF390838	158	16	74188233	74188390	Rat	region
5081677	BE117978	186	16	73370013	73370198	Rat	region
5083591	BI276346	158	16	73788574	73788731	Rat	region
5507705	UniSTS:25220	0	16	75193146	75193758	Rat	region
5505044	Myst3	249	16	74020188	74020436	Rat	region
5505046	Myst3	156	16	73943924	73944079	Rat	region
5505372	Atp7b	858	16	74906171	74907028	Rat	region
5505768	UniSTS:492990	859	16	75647680	75648538	Rat	region
5502928	Sfrp1	781	16	73374339	73375119	Rat	region
5502817	VDAC3	177	16	74302059	74303682	Rat	region

Position Markers

Flank 1: (D16Rat42)

Rat Assembly	Chr	Position (strand)	Source
Celera	16	65,511,878 - 65,512,027	UniSTS
RH 3.4 Map	16	640.0	RGD
RH 3.4 Map	16	640.0	UniSTS
RH 2.0 Map	16	768.4	RGD
SHRSP x BN Map	16	33.9399	RGD

Peak: (D16Rat55)

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	16	76,667,628 - 76,667,805	NCBI
Rnor_5.0	16	76,270,497 - 76,270,674	UniSTS
RGSC_v3.4	16	76,622,103 - 76,622,281	RGD
RGSC_v3.4	16	76,622,104 - 76,622,281	UniSTS
RGSC_v3.1	16	76,622,369 - 76,622,546	RGD
Celera	16	69,610,546 - 69,610,723	UniSTS
RH 3.4 Map	16	702.2	UniSTS
RH 3.4 Map	16	702.2	RGD
RH 2.0 Map	16	815.0	RGD
SHRSP x BN Map	16	38.59	RGD

Flank 2: (D16Rat48)

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	16	80,115,641 - 80,115,794	NCBI
Rnor_5.0	16	79,690,255 - 79,690,408	UniSTS
RGSC_v3.4	16	79,850,041 - 79,850,195	RGD
RGSC_v3.4	16	79,850,042 - 79,850,195	UniSTS
RGSC_v3.1	16	79,850,307 - 79,850,460	RGD
Celera	16	72,845,336 - 72,845,489	UniSTS
Cytogenetic Map	16	q12.5	UniSTS
RH 3.4 Map	16	730.4	RGD
RH 3.4 Map	16	730.4	UniSTS
SHRSP x BN Map	16	45.5099	UniSTS
SHRSP x BN Map	16	45.5099	RGD

QTLs in Region (Rnor_6.0)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1600378	Arunc4	Aerobic running capacity QTL 4		0.03	exercise endurance trait (VT:0002332)	maximum distance run on treadmill (CMO:0001406)	16	1090054	86162972	Rat
70215	Niddm29	Non-insulin dependent diabetes mellitus QTL 29	3.54		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	16	20755556	80316424	Rat
6903294	Stl30	Serum triglyceride level QTL 30	2.6	0.0013	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	16	28340315	73340315	Rat
1578768	Stresp22	Stress response QTL 22	2.8		thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	16	39000021	84000021	Rat
2300163	Bmd64	Bone mineral density QTL 64	5.3	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	16	41512710	86512710	Rat
2293690	Bss45	Bone structure and strength QTL 45	5.13	0.0001	lumbar vertebra morphology trait (VT:0010494)	lumbar vertebra cortical cross-sectional area (CMO:0001690)	16	41512710	86512710	Rat
7205510	Activ5	Activity QTL 5	3.78	0.00028	locomotor behavior trait (VT:0001392)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	16	46558188	90668790	Rat
7411648	Foco22	Food consumption QTL 22	15	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	16	57816357	90668790	Rat
8694429	Bw164	Body weight QTL 164	5	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	16	57816357	90668790	Rat
8694364	Abfw7	Abdominal fat weight QTL 7	12.22	0.001	visceral adipose mass (VT:0010063)	abdominal fat pad weight to body weight ratio (CMO:0000095)	16	57816357	90668790	Rat
631525	Pia14	Pristane induced arthritis QTL 14	4.4		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	16	59285775	89248943	Rat
1298527	Arunc2	Aerobic running capacity QTL 2	2.9		exercise endurance trait (VT:0002332)	maximum distance run on treadmill (CMO:0001406)	16	73219638	80115794	Rat

Additional Information

External Database Links

Database	Acc Id	Source(s)
NCBI Gene	Arunc2

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2006-04-14	Arunc2	Aerobic running capacity QTL 2	Arc2		Symbol updated	1299863	APPROVED

RGD Curation Notes

Note Type	Note	Reference
qtl_cand_genes	candidate genes RGD1306769, Pdlim3, Ppif detect differential expression in in the left ventricles of high aerobic capacity vs. low aerobic capacity strains; candidate genes Irs2, Acsl1 are members of biological networks containing differentially expressed genes	1547852
qtl_general	only male rats were used in this study	619535
qtl_general	a significant interaction was found with Arc3; rats homozygous for DA allele at both marker loci had 42% higher running distances than those homozygous for COP allele	619535

More on Arunc2
	JBrowse: rn5 rn6
	QTL Registration

RGD Object Information
RGD ID:	1298527
Created:	2004-05-14
Species:	Rattus norvegicus
Last Modified:	2006-04-14
Status:	ACTIVE

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.