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Strain Registration

Strain: BBDR.BBDP-(D4Mit6-D4Mit7)/RhwMcwi-Il1r1em3Mcwi

Symbol: BBDR.BBDP-(D4Mit6-D4Mit7)/RhwMcwi-Il1r1em3Mcwi
Strain: BBDR.BBDP-(D4Mit6-D4Mit7)/RhwMcwi-Il1r1em3
Substrain: Mcwi
RGD ID: 6893382
Citation ID: RRID:RGD_6893382
Ontology ID: RS:0003293
Alleles: Il1r1em3Mcwi
Also Known As: BBDR.BBDP-(D4Mit6-D4Mit7)/RhwMcwi-Il1r1em3Mcwi; BBDR.BBDP-(D4Mit6-D4Mit7)/RhwMcwi-Il1r1^[em3Mcwi]
Type: mutant
Available Source: Not Available
Origination: PhysGen Knockouts
Description: This strain was produced by injecting ZFNs targeting the sequence AGCTTCATACAGCGGCtccatgTTGCAGGGGATGGAAGTC into BBDR.BBDP-(D4Mit6-D4Mit7)/RhwMcwi rat embryos. The resulting mutation is a 1-bp insertion in exon 5.
Last Known Status: Cryorecovery (as of 2017-01-26)
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2942,565,971 - 42,565,972RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.0946,962,291 - 47,038,139RGD_MAPPER_PIPELINERnor6.0
Rnor_5.0946,647,422 - 46,723,241RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.4939,434,910 - 39,473,552RGD_MAPPER_PIPELINERGSC3.4






References

References - curated
# Reference Title Reference Citation
1. Knockout rats via embryo microinjection of zinc-finger nucleases. Geurts AM, etal., Science. 2009 Jul 24;325(5939):433.
2. PhysGen Knockouts PhysGen Knockout strains
3. RGD Strain RSO annotation pipeline RGD Automated Pipelines

Region

Position Markers

Flank 1 / 1 (D4Mit6)
Rat AssemblyChrPosition (strand)Source
mRatBN7.2476,647,384 - 76,647,568 (+)MAPPER
Rnor_6.0477,307,388 - 77,307,571NCBI
Rnor_5.04141,978,848 - 141,979,031UniSTS
RGSC_v3.4475,732,943 - 75,733,127RGD
RGSC_v3.4475,732,944 - 75,733,127UniSTS
Celera471,452,122 - 71,452,305UniSTS
Cytogenetic Map4q24UniSTS

Flank 2 / 1 (D4Mit7)
Rat AssemblyChrPosition (strand)Source
mRatBN7.2478,885,890 - 78,886,189 (+)MAPPER
Rnor_6.0479,562,451 - 79,562,753RGD
Allelic Variants
Name Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Assembly
Il1r1em3Mcwi-var1 chr9 42565971 42565972 - A insertion mRatBN7.2

Additional Information


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2014-04-03 BBDR.BBDP-(D4Mit6-D4Mit7)/RhwMcwi-Il1r1em3Mcwi    BBDR.BBDP-(D4Mit6-D4Mit7)/RhwMcwi-Il1r1em3Mcwi    Symbol updated 68687 APPROVED
2014-04-03 BBDR.BBDP-(D4Mit6-D4Mit7)/RhwMcwi-Il1r1em3Mcwi    BBDR.BBDP-(D4Mit6-D4Mit7)/RhwMcwi-Il1r1em3Mcwi    Name updated 68913 APPROVED
2014-04-03 BBDR.BBDP-(D4Mit6-D4Mit7)/RhwMcwi-Il1r1em3Mcwi    BBDR.BBDP-(D4Mit6-D4Mit7)/RhwMcwi-Il1r1em3Mcwi    Symbol updated 68687 APPROVED
2014-04-03 BBDR.BBDP-(D4Mit6-D4Mit7)/RhwMcwi-Il1r1em3Mcwi    BBDR.BBDP-(D4Mit6-D4Mit7)/RhwMcwi-Il1r1em3Mcwi    Name updated 68913 APPROVED
2013-08-15 BBDR.BBDP-(D4Mit6-D4Mit7)/RhwMcwi-Il1r1em3Mcwi    BBDR.BBDP-(D4Mit6-D4Mit7)/RhwMcwi-Il1r1em3Mcwi    Name updated 68913 APPROVED
2013-08-15 BBDR.BBDP-(D4Mit6-D4Mit7)/RhwMcwi-Il1r1em3Mcwi    BBDR.BBDP-(D4Mit6-D4Mit7)/RhwMcwi-Il1r1em3Mcwi    Name updated 68913 APPROVED
2012-08-28 BBDR.BBDP-(D4Mit6-D4Mit7)/RhwMcwi-Il1r1em3Mcwi    BBDR.BBDP-(D4Mit6-D4Mit7)/RhwMcwi-Il1r1em3Mcwi    Name updated 68913 APPROVED
2012-08-28 BBDR.BBDP-(D4Mit6-D4Mit7)/RhwMcwi-Il1r1em3Mcwi    BBDR.BBDP-(D4Mit6-D4Mit7)/RhwMcwi-Il1r1em3Mcwi    Name updated 68913 APPROVED