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Gene: Cntnap2 (contactin associated protein 2) Rattus norvegicus
Symbol: Cntnap2
Name: contactin associated protein 2
Description: Exhibits ion channel binding activity and protease binding activity. Predicted to be involved in several processes, including nervous system development; protein localization to juxtaparanode region of axon; and vocal learning. Localizes to several cellular components, including main axon; neuronal cell body; and synaptic membrane. Used to study visual epilepsy. Human ortholog(s) of this gene implicated in several diseases, including Pitt-Hopkins syndrome; autism spectrum disorder (multiple); communication disorder (multiple); cortical dysplasia-focal epilepsy syndrome; and social phobia. Orthologous to human CNTNAP2 (contactin associated protein 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; tetrachloromethane.
Type: protein-coding
RefSeq Status: MODEL
Also known as: contactin associated protein-like 2; contactin-associated protein-like 2; LOC100364190; LOC362355; LOC500105; LOW QUALITY PROTEIN: contactin-associated protein-like 2; mKIAA0868 protein-like; similar to contactin associated protein-like 2 isoform a
Homo sapiens (human) : CNTNAP2 (contactin associated protein 2)  HGNC  Alliance
Mus musculus (house mouse) : Cntnap2 (contactin associated protein-like 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cntnap2 (contactin associated protein 2)
Pan paniscus (bonobo/pygmy chimpanzee) : CNTNAP2 (contactin associated protein 2)
Canis lupus familiaris (dog) : CNTNAP2 (contactin associated protein 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cntnap2 (contactin associated protein 2)
Sus scrofa (pig) : CNTNAP2 (contactin associated protein 2)
Chlorocebus sabaeus (African green monkey) : CNTNAP2 (contactin associated protein 2)
Heterocephalus glaber (naked mole-rat) : Cntnap2 (contactin associated protein 2)
more info ...
Allele / Splice: Cntnap2em1Sage  
Genetic Models: SD-Cntnap2em1Sage
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0474,700,539 - 77,025,463 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04140,006,078 - 140,855,979 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.04141,164,125 - 141,697,964 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4474,277,978 - 75,440,178 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1475,661,775 - 75,716,308 (+)NCBI
Celera468,984,397 - 71,173,021 (+)NCBICelera
Cytogenetic Map4q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models



Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Cntnap2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1307076
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-07-28
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.